Lista de obras - Michael R Barnes - Dominio Público Uruguay

A 3-(3-hydroxyphenyl)propionic acid catabolic pathway in Rhodococcus globerulus PWD1: cloning and characterization of the hpp operon ⬇️

artículo científico publicado el 1 de octubre de 1997

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.

artículo científico publicado en 2014

A COMT gene haplotype associated with methamphetamine abuse.

artículo científico publicado en 2011

A mega-analysis of genome-wide association studies for major depressive disorder

artículo científico publicado en 2012

A short primer on the functional analysis of copy number variation for biomedical scientists

artículo científico publicado en 2010

ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation

scientific article published on 15 January 2011

Advances in blood pressure genomics

artículo científico

An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection

artículo científico publicado en 2016

Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation

artículo científico publicado en 2016

Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma

article

Bioinformatics for dermatology - why we should learn about code.

artículo científico publicado en 2017

C20orf9-003 (ACI-1), a gene localized on chromosome 20q13.12 encoding for a 49 kD cytoplasmic protein with a putative nucleotide binding site

artículo científico publicado en 2004

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

artículo científico publicado en 2007

Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery

artículo científico publicado en 2016

Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes

artículo científico publicado en 2012

Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.

artículo científico publicado en 2017

Correlation of protein and gene expression profiles of inflammatory proteins after endotoxin challenge in human subjects.

artículo científico publicado en 2005

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Disruption of the neurexin 1 gene is associated with schizophrenia

artículo científico publicado en 2009

Drug discovery in the extracellular matrix

artículo científico publicado en 2008

Enhanced Energetic State and Protection from Oxidative Stress in Human Myoblasts Overexpressing BMI1.

artículo científico publicado en 2017

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

artículo científico publicado en 2021

Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates

scientific article published on 18 September 2020

Erratum: Whole-genome sequence-based analysis of thyroid function

artículo científico publicado en 2015

Establishing an Academic–Industrial Stratified Medicine Consortium: Psoriasis Stratification to Optimize Relevant Therapy

artículo científico publicado en 2015

Evaluation of splenic switch off in a tertiary imaging centre: validation and assessment of utility

artículo científico

Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

artículo científico

Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland

artículo científico publicado en 2001

Feasibility of real-time capture of routine clinical data in the electronic health record: a hospital-based, observational service-evaluation study.

artículo científico publicado en 2018

Frizzled proteins constitute a novel family of G protein-coupled receptors, most closely related to the secretin family

artículo científico publicado en 1998

FrzB-2: a human secreted frizzled-related protein with a potential role in chondrocyte apoptosis.

artículo científico publicado en 2000

Gene Ranking of RNA-Seq Data via Discriminant Non-Negative Matrix Factorization.

artículo científico publicado en 2015

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

artículo científico publicado en 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

artículo científico publicado en 2014

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

artículo científico publicado en 2015

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

artículo científico publicado en 2013

Genetic variation analysis for biomedical researchers: a primer

scientific article published on January 2010

Genome-wide association analysis of copy number variation in recurrent depressive disorder.

artículo científico publicado en 2011

Genome-wide association study of major recurrent depression in the U.K. population

artículo científico publicado en 2010

Genome-wide pharmacogenetics of antidepressant response in the GENDEP project

artículo científico publicado en 2010

Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

artículo científico publicado en 2016

Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualization of genome wide association studies

artículo científico publicado en 2008

Health and population effects of rare gene knockouts in adult humans with related parents

artículo científico publicado en 2016

Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design

artículo científico publicado en 2016

IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty

artículo científico publicado en 2016

Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity

artículo científico publicado en 2002

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

artículo científico publicado en 2015

Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery

artículo científico publicado en 2009

M3C: Monte Carlo reference-based consensus clustering

scientific article published on 04 February 2020

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

artículo científico publicado en 2016

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Navigating the HapMap

artículo científico publicado en 2006

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

scientific article published on 13 March 2009

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

artículo científico publicado en 2014

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder

artículo científico publicado en 2015

Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.

artículo científico publicado en 2007

Precision phenotyping, panomics, and system-level bioinformatics to delineate complex biologies of atherosclerosis: rationale and design of the "Genetic Loci and the Burden of Atherosclerotic Lesions" study

artículo científico publicado en 2014

Psychiatric genetics in silico: databases and tools for psychiatric geneticists

artículo científico publicado en 2002

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

RNA sequencing and machine learning as molecular scalpels

scientific article published on 01 July 2018

Reply to Rational drug repositioning by medical genetics

artículo científico publicado en 2013

Research Techniques Made Simple: Bioinformatics for Genome-Scale Biology

artículo científico

Risk in drug trials

artículo científico publicado en 2006

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

scientific article published on 19 May 2022

Role for WNT16B in human epidermal keratinocyte proliferation and differentiation

artículo científico publicado en 2007

Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment

artículo científico publicado en 2016

SNP and mutation data on the web - hidden treasures for uncovering

artículo científico publicado en 2002

Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study

artículo científico publicado en 2017

Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo

artículo científico publicado en 2015

Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants.

artículo científico publicado en 2015

Specific loss of connexin 26 expression in ductal sweat gland epithelium associated with the deletion mutation del(GJB6-D13S1830).

artículo científico publicado en 2005

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

scientific article published on 05 December 2019

The RA-MAP Consortium: a working model for academia-industry collaboration. ⬇️

artículo científico publicado en 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression

artículo científico publicado en 2007

Tissue restricted expression of two human Frzbs in preadipocytes and pancreas

artículo científico publicado en 1998

Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia

artículo científico publicado en 2011

Two variants of the C-reactive protein gene are associated with risk of pre-eclampsia in an American Indian population

artículo científico publicado en 2013

Use of genome-wide association studies for drug repositioning

Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis

artículo científico publicado en 2011

Whole-genome sequence-based analysis of thyroid function.

artículo científico publicado en 2015

visxhclust: An R Shiny package for visual exploration of hierarchical clustering

scientific article published on 05 February 2022

Lista de obras de Michael R Barnes

A 3-(3-hydroxyphenyl)propionic acid catabolic pathway in Rhodococcus globerulus PWD1: cloning and characterization of the hpp operon ⬇️

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.

A COMT gene haplotype associated with methamphetamine abuse.

A mega-analysis of genome-wide association studies for major depressive disorder

A short primer on the functional analysis of copy number variation for biomedical scientists

ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation

Advances in blood pressure genomics

An ectopically expressed serum miRNA signature is prognostic, diagnostic, and biologically related to liver allograft rejection

Artesunate Protects Against the Organ Injury and Dysfunction Induced by Severe Hemorrhage and Resuscitation

Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma

Bioinformatics for dermatology - why we should learn about code.

C20orf9-003 (ACI-1), a gene localized on chromosome 20q13.12 encoding for a 49 kD cytoplasmic protein with a putative nucleotide binding site

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery

Common genetic variants and gene-expression changes associated with bipolar disorder are over-represented in brain signaling pathway genes

Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.

Correlation of protein and gene expression profiles of inflammatory proteins after endotoxin challenge in human subjects.

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Disruption of the neurexin 1 gene is associated with schizophrenia

Drug discovery in the extracellular matrix

Enhanced Energetic State and Protection from Oxidative Stress in Human Myoblasts Overexpressing BMI1.

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates

Erratum: Whole-genome sequence-based analysis of thyroid function

Establishing an Academic–Industrial Stratified Medicine Consortium: Psoriasis Stratification to Optimize Relevant Therapy

Evaluation of splenic switch off in a tertiary imaging centre: validation and assessment of utility

Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland

Feasibility of real-time capture of routine clinical data in the electronic health record: a hospital-based, observational service-evaluation study.

Frizzled proteins constitute a novel family of G protein-coupled receptors, most closely related to the secretin family

FrzB-2: a human secreted frizzled-related protein with a potential role in chondrocyte apoptosis.

Gene Ranking of RNA-Seq Data via Discriminant Non-Negative Matrix Factorization.

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Genetic variation analysis for biomedical researchers: a primer

Genome-wide association analysis of copy number variation in recurrent depressive disorder.

Genome-wide association study of major recurrent depression in the U.K. population

Genome-wide pharmacogenetics of antidepressant response in the GENDEP project

Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

Goldsurfer2 (Gs2): a comprehensive tool for the analysis and visualization of genome wide association studies

Health and population effects of rare gene knockouts in adult humans with related parents

Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design

IGSF10 mutations dysregulate gonadotropin-releasing hormone neuronal migration resulting in delayed puberty

Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Lowering industry firewalls: pre-competitive informatics initiatives in drug discovery

M3C: Monte Carlo reference-based consensus clustering

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

Navigating the HapMap

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder

Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.

Precision phenotyping, panomics, and system-level bioinformatics to delineate complex biologies of atherosclerosis: rationale and design of the "Genetic Loci and the Burden of Atherosclerotic Lesions" study

Psychiatric genetics in silico: databases and tools for psychiatric geneticists

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

RNA sequencing and machine learning as molecular scalpels

Reply to Rational drug repositioning by medical genetics

Research Techniques Made Simple: Bioinformatics for Genome-Scale Biology

Risk in drug trials

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

Role for WNT16B in human epidermal keratinocyte proliferation and differentiation

Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment

SNP and mutation data on the web - hidden treasures for uncovering

Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study

Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo

Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants.

Specific loss of connexin 26 expression in ductal sweat gland epithelium associated with the deletion mutation del(GJB6-D13S1830).

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

The RA-MAP Consortium: a working model for academia-industry collaboration. ⬇️

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals