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Lista de obras de Larry Norton

1st International consensus guidelines for advanced breast cancer (ABC 1).

artículo científico

21-Gene recurrence score and locoregional recurrence in lymph node-negative, estrogen receptor-positive breast cancer

artículo científico

5-year results of dose-intensive sequential adjuvant chemotherapy for women with high-risk node-positive breast cancer: A phase II study

artículo científico publicado en 1999

A CXCL1 paracrine network links cancer chemoresistance and metastasis

artículo científico publicado en 2012

A Phase I Study of Cetuximab/Paclitaxel in Patients with Advanced-Stage Breast Cancer

artículo científico publicado en 2006

A Pilot Study of Dose-Dense Paclitaxel With Trastuzumab and Lapatinib for Node-negative HER2-Overexpressed Breast Cancer

artículo científico publicado en 2015

A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling

artículo científico publicado en 2016

A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer

artículo científico publicado en 2016

A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment

artículo científico publicado en 2004

A feasibility study of bevacizumab plus dose-dense doxorubicin-cyclophosphamide (AC) followed by nanoparticle albumin-bound paclitaxel in early-stage breast cancer

artículo científico publicado en 2011

A phase I study of dasatinib and weekly paclitaxel for metastatic breast cancer

artículo científico publicado en 2011

A phase I-II study of intensive-dose adriamycin for advanced breast cancer

artículo científico publicado en 1987

A phase II trial of erlotinib in combination with bevacizumab in patients with metastatic breast cancer

artículo científico publicado en 2008

A phase II trial of extracorporeal plasma immunoadsorption of patient plasma with prosorba columns for treating metastatic breast cancer ⬇️

artículo científico publicado el 15 de abril de 1995

A phase II trial of gemcitabine in patients with metastatic breast cancer previously treated with an anthracycline and taxane.

artículo científico publicado en 2005

A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer.

artículo científico publicado en 2005

A pilot study of dose-dense adjuvant paclitaxel without growth factor support for women with early breast carcinoma

article

A pilot study of interpersonal psychotherapy by telephone with cancer patients and their partners

artículo científico publicado en 2000

A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer

artículo científico publicado en 2003

A tool for predicting breast carcinoma mortality in women who do not receive adjuvant therapy.

artículo científico publicado en 2004

Abstract 3282: Determination of cancer susceptibility in probands with breast and ovarian cancer

article published in 2014

Acquired resistance to crizotinib from a mutation in CD74-ROS1.

artículo científico publicado en 2013

Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer

artículo científico publicado en 2005

Adjuvant chemotherapy in older women with early-stage breast cancer

artículo científico publicado en 2009

Adjuvant drug therapy for operable breast cancer.

artículo científico publicado en 1996

Adjuvant trastuzumab with chemotherapy is effective in women with small, node-negative, HER2-positive breast cancer

Advances in managing breast cancer: a clinical update

artículo científico publicado en 2014

American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

artículo científico publicado en 2007

An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis

artículo científico publicado en 2017

An experimental analysis of classically conditioned nausea during cancer chemotherapy

artículo científico publicado el 1 de noviembre de 1992

An immunotherapeutic approach to treatment of breast cancer: focus on trastuzumab plus paclitaxel. Breast Cancer Medicine Service

artículo científico publicado en 2000

An intensive sequenced adjuvant chemotherapy regimen for breast cancer

scientific article published on 01 January 1993

Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping

artículo científico publicado en 2008

Antibody and CD8+ T cell responses against HER2/neu required for tumor eradication after DNA immunization with a Flt-3 ligand fusion vaccine

artículo científico publicado en 2007

Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies

scientific article published on 01 August 1993

Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: a clinic-based series

artículo científico publicado en 2005

Arterial thrombosis associated with adjuvant chemotherapy for breast carcinoma: a Cancer and Leukemia Group B Study

scientific article published on 01 November 1989

Assessment of molecular markers of clinical sensitivity to single-agent taxane therapy for metastatic breast cancer

artículo científico publicado en 2002

Association between bone mineral density and incidence of breast cancer

artículo científico publicado en 2013

Association of Angiogenesis in Lymph Node Metastases With Outcome of Breast Cancer

artículo científico publicado en 2000

Association of angiogenesis and disease outcome in node-positive breast cancer patients treated with adjuvant cyclophosphamide, doxorubicin, and fluorouracil: a Cancer and Leukemia Group B correlative science study from protocols 8541/8869.

artículo científico publicado en 2002

BRCA-associated breast cancer in young women ⬇️

artículo científico publicado el 1 de mayo de 1998

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations

artículo científico publicado en 2014

Biomarkers That Predict Sensitivity to Heat Shock Protein 90 Inhibitors

artículo científico publicado en 2015

Breast cancer methylomes establish an epigenomic foundation for metastasis

artículo científico publicado en 2011

Breast cancer survivors are at an increased risk for osteoporotic fractures not explained by lower BMD: a retrospective analysis

artículo científico publicado en 2015

Breast cancer tumor size, nodal status, and prognosis: biology trumps anatomy

artículo científico publicado en 2011

Breast carcinoma with 21-gene recurrence score lower than 18: rate of locoregional recurrence in a large series with clinical follow-up

artículo científico publicado en 2018

Breast carcinoma with an Oncotype Dx recurrence score <18: Rate of distant metastases in a large series with clinical follow-up

artículo científico publicado en 2016

Breast conservation therapy for invasive breast cancer in Ashkenazi women with BRCA gene founder mutations.

artículo científico

Can we really use retrospective subset analyses and surveillance, epidemiology, and end results data to drive clinical practice?

artículo científico publicado en 2012

Cancer stem cells, EMT, and seeding: a rose is a rose is a rose?

artículo científico publicado el 1 de enero de 2011

Cancer stem cells, self-seeding, and decremented exponential growth: theoretical and clinical implications.

artículo científico publicado en 2008

Capecitabine dosing is not yet optimized for breast cancer

artículo científico publicado en 2010

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.

artículo científico

Carboplatin and etoposide in metastatic breast cancer

scientific article published on 01 April 1995

Cardiac Surveillance Guidelines for Trastuzumab-Containing Therapy in Early-Stage Breast Cancer: Getting to the Heart of the Matter

artículo científico publicado en 2016

Change in cycle 1 to cycle 2 haematological counts predicts toxicity in older patients with breast cancer receiving adjuvant chemotherapy

artículo científico publicado en 2005

Changing indications for surgery in patients with stage IV breast cancer: a current perspective

artículo científico publicado en 2008

Choosing the best trastuzumab-based adjuvant chemotherapy regimen: should we abandon anthracyclines?

artículo científico publicado en 2012

Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B Study 8662.

artículo científico publicado en 2001

Clinical cardiotoxicity of esorubicin (4'-deoxydoxorubicin,DxDx): prospective studies with serial gated heart scans and reports of selected cases. A Cancer and Leukemia Group B report

artículo científico publicado en 1990

Clinical implications of cancer self-seeding

artículo científico publicado en 2011

Cold thermal injury from cold caps used for the prevention of chemotherapy-induced alopecia

artículo científico publicado en 2016

Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study

artículo científico publicado en 2007

Comparison of HER2 status by fluorescence in situ hybridization and immunohistochemistry to predict benefit from dose escalation of adjuvant doxorubicin-based therapy in node-positive breast cancer patients

artículo científico publicado en 2005

Comparison of doxorubicin and cyclophosphamide versus single-agent paclitaxel as adjuvant therapy for breast cancer in women with 0 to 3 positive axillary nodes: CALGB 40101 (Alliance).

artículo científico publicado en 2014

Conceptual and practical implications of breast tissue geometry: toward a more effective, less toxic therapy

artículo científico publicado en 2005

Conditioned emotional distress in women receiving chemotherapy for breast cancer

artículo científico publicado en 1995

Current management of lesions associated with an increased risk of breast cancer

artículo científico publicado en 2015

Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.

artículo científico publicado en 2002

Cytokeratin-positive cells in sentinel lymph nodes in breast cancer are not random events

DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors

article

Decreased gastrointestinal toxicity associated with a novel capecitabine schedule (7 days on and 7 days off): a systematic review

artículo científico

Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy

artículo científico publicado en 2016

Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations

artículo científico publicado en 2000

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss

artículo científico publicado en 2015

Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors

artículo científico publicado en 2015

Discussion

Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer

artículo científico publicado en 2017

Dose and dose intensity of adjuvant chemotherapy for stage II, node-positive breast carcinoma

artículo científico publicado en 1994

Dose dense cyclophosphamide, methotrexate, fluorouracil is feasible at 14-day intervals: a pilot study of every-14-day dosing as adjuvant therapy for breast cancer

artículo científico publicado en 2010

Dose-Dense Chemotherapy With Trastuzumab Is an Appropriate Option

Dose-dense adjuvant Doxorubicin and cyclophosphamide is not associated with frequent short-term changes in left ventricular ejection fraction

artículo científico publicado en 2009

Dose-dense adjuvant chemotherapy for primary breast cancer

artículo científico publicado en 2005

Dose-dense chemotherapy for breast cancer: what does the future hold?

scientific article published on June 2010

Dose-dense doxorubicin and cyclophosphamide followed by weekly paclitaxel with trastuzumab and lapatinib in HER2/neu-overexpressed/amplified breast cancer is not feasible because of excessive diarrhea

artículo científico publicado en 2010

Dose-dense therapy with paclitaxel via weekly 1-hour infusion: preliminary experience in the treatment of metastatic breast cancer.

artículo científico publicado en 1997

Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer

artículo científico publicado en 1998

Dose-escalation of filgrastim does not improve efficacy: clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide follow

artículo científico publicado en 2008

Dose-intensity, dose-escalation, and dose-density in the adjuvant chemotherapy of primary, operable breast cancer

artículo científico publicado en 2001

Doxorubicin followed by sequential paclitaxel and cyclophosphamide versus concurrent paclitaxel and cyclophosphamide: 5-year results of a phase II randomized trial of adjuvant dose-dense chemotherapy for women with node-positive breast carcinoma

artículo científico publicado en 2001

Duration of letrozole treatment and outcomes in the placebo-controlled NCIC CTG MA.17 extended adjuvant therapy trial

article

E6. Can an international consensus meeting change the future of advanced breast cancer patients? Highlights from ABC1 Consensus Meeting

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2).

artículo científico publicado en 2014

ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)†

artículo científico publicado en 2014

Effect of Addition of Adjuvant Paclitaxel on Radiotherapy Delivery and Locoregional Control of Node-Positive Breast Cancer: Cancer and Leukemia Group B 9344

article

Effect of adjuvant breast cancer chemotherapy on cognitive function from the older patient's perspective

artículo científico publicado en 2006

Effect of creatinine clearance on patterns of toxicity in older patients receiving adjuvant chemotherapy for breast cancer

artículo científico publicado en 2005

Efficacy of Letrozole Extended Adjuvant Therapy According to Estrogen Receptor and Progesterone Receptor Status of the Primary Tumor: National Cancer Institute of Canada Clinical Trials Group MA.17

article

Epoetin alfa: to give or not to give

artículo científico publicado en 2013

Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer

artículo científico publicado en 2006

Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis

artículo científico publicado en 2000

Expression of WT1, CA 125, and GCDFP-15 as Useful Markers in the Differential Diagnosis of Primary Ovarian Carcinomas Versus Metastatic Breast Cancer to the Ovary

article

Expression of osteoprotegerin (OPG), TNF related apoptosis inducing ligand (TRAIL), and receptor activator of nuclear factor kappaB ligand (RANKL) in human breast tumours

artículo científico publicado en 2006

Factors affecting the mobilization of primitive and committed hematopoietic progenitors into the peripheral blood of cancer patients

artículo científico publicado en 1994

Factors influencing prognosis in node-negative breast carcinoma: analysis of 767 T1N0M0/T2N0M0 patients with long-term follow-up

scientific article published on 01 November 1993

Factors influencing treatment patterns of breast cancer patients age 75 and older

artículo científico publicado en 2003

Failure of higher-dose paclitaxel to improve outcome in patients with metastatic breast cancer: cancer and leukemia group B trial 9342.

artículo científico publicado en 2004

Feasibility trial of letrozole in combination with bevacizumab in patients with metastatic breast cancer

scientific article published on 19 October 2009

Fifteen-year median follow-up results after neoadjuvant doxorubicin, followed by mastectomy, followed by adjuvant cyclophosphamide, methotrexate, and fluorouracil (CMF) followed by radiation for stage III breast cancer: a phase II trial (CALGB 8944)

artículo científico publicado en 2009

First-in-Human Trial of Epichaperome-Targeted Positron Emission Tomography in Cancer Patients

scientific article published on 04 May 2020

Focus on breast cancer

artículo científico publicado en 2002

Formation of food aversions in cancer patients receiving repeated infusions of chemotherapy.

artículo científico publicado en 1993

Fractional SIR Epidemiological Models

artículo científico publicado en 2020

Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families

artículo científico publicado en 1996

Frequent mutational activation of the PI3K-AKT pathway in trastuzumab-resistant breast cancer

artículo científico publicado en 2012

Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast Cancers and Their Metastases

artículo científico publicado en 2017

Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology

artículo científico publicado en 2016

Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family

artículo científico publicado en 2016

Genetic analysis of uterine adenosarcomas and phyllodes tumors of the breast

artículo científico publicado en 2017

Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant

article

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

artículo científico publicado en 2008

Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast

artículo científico publicado en 2017

Genomic landscape of adenoid cystic carcinoma of the breast

artículo científico publicado en 2015

Germline BRCA mutations denote a clinicopathologic subset of prostate cancer

artículo científico publicado en 2010

Germline BRCA1 185delAG mutations in Jewish women with breast cancer

scientific article published on 01 June 1996

HER-2/neu and p53 expression versus tamoxifen resistance in estrogen receptor-positive, node-positive breast cancer

artículo científico publicado en 2000

HER2 and Response to Paclitaxel in Node-Positive Breast Cancer

article

HER2 overexpression and paclitaxel sensitivity in breast cancer: therapeutic implications

artículo científico publicado en 1997

HSP90 inhibition is effective in breast cancer: a phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on trastuzumab.

artículo científico publicado en 2011

Heterogenic loss of the wild-type BRCA allele in human breast tumorigenesis

artículo científico publicado en 2007

High-dose chemotherapy for breast cancer: "how do you know?"

artículo científico publicado en 2001

High-dose chemotherapy of breast cancer.

artículo científico publicado en 1995

High-dose chemotherapy of breast cancer: Current status and developmental strategies ⬇️

artículo científico publicado el 1 de enero de 1995

High-dose versus standard chemotherapy in metastatic breast cancer: comparison of Cancer and Leukemia Group B trials with data from the Autologous Blood and Marrow Transplant Registry

artículo científico publicado en 2002

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

artículo científico publicado en 2014

Hyperglycemic complications associated with adjuvant chemotherapy of breast cancer. A cancer and leukemia group B (CALGB) study

scientific article published on 01 December 1986

Id4 protein is highly expressed in triple-negative breast carcinomas: possible implications for BRCA1 downregulation

artículo científico publicado en 2012

Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21.

artículo científico publicado en 2007

Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial

artículo científico publicado en 2001

Immunohistochemical detection of HER2/neu in patients with axillary lymph node negative breast carcinoma. A study of epidemiologic risk factors, histologic features, and prognosis

artículo científico publicado en 1995

Immunohistochemical detection of cathepsin D in T2N0M0 breast carcinoma

scientific article published on 01 February 1994

Immunophenotype of intraductal carcinoma

scientific article published on 01 January 1996

Impact of high-dose chemotherapy on the ability to deliver subsequent local-regional radiotherapy for breast cancer: analysis of Cancer and Leukemia Group B Protocol 9082.

artículo científico publicado en 2009

Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer.

artículo científico publicado en 2003

In Reply:

In Reply:

article published in 2003

Incidence of chemotherapy-induced, long-term amenorrhea in patients with breast carcinoma age 40 years and younger after adjuvant anthracycline and taxane

artículo científico publicado en 2005

Increased Dose Density Is Feasible: A Pilot Study of Adjuvant Epirubicin and Cyclophosphamide followed by Paclitaxel, at 10- or 11-Day Intervals with Filgrastim Support in Women with Breast Cancer

article

Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B.

artículo científico publicado en 2008

Inhibitors of HSP90 block p95-HER2 signaling in Trastuzumab-resistant tumors and suppress their growth

artículo científico publicado en 2009

Intent-to-treat analysis of the placebo-controlled trial of letrozole for extended adjuvant therapy in early breast cancer: NCIC CTG MA.17.

artículo científico publicado en 2008

Interleukin-6, multidrug resistance protein-1 expression and response to paclitaxel in women with metastatic breast cancer: results of cancer and leukemia group B trial 159806

article

Intra-tumor genetic heterogeneity and alternative driver genetic alterations in breast cancers with heterogeneous HER2 gene amplification

artículo científico publicado en 2015

Intracystic papillary carcinoma of the breast: An in situ or invasive tumor? Results of immunohistochemical analysis and clinical follow-up

artículo científico publicado en 2011

Is cancer a disease of self-seeding?

JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors

artículo científico publicado en 2016

Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen

artículo científico publicado en 2008

Latent bone metastasis in breast cancer tied to Src-dependent survival signals

artículo científico publicado en 2009

Living with metastatic breast cancer: a qualitative analysis of physical, psychological, and social sequelae

artículo científico publicado en 2013

Localization of breast cancer susceptibility loci by genome-wide SNP linkage disequilibrium mapping

article published in 2005

Long-term adjustment of survivors of early-stage breast carcinoma, 20 years after adjuvant chemotherapy

artículo científico publicado en 2003

Long-term cardiac safety and outcomes of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel and trastuzumab with and without lapatinib in patients with early breast cancer

artículo científico publicado en 2013

Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors

scientific article published in Nature Communications

Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer

artículo científico publicado en 2004

MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB-NFIB fusion gene

artículo científico publicado en 2017

Massively parallel sequencing analysis of synchronous fibroepithelial lesions supports the concept of progression from fibroadenoma to phyllodes tumor

artículo científico publicado en 2016

Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression

artículo científico publicado en 2015

Matched T cell repertoire analysis of peripheral blood and tumor-infiltrating lymphocytes (TILs) in early stage breast cancer (ESBC) patients (pts) treated with pre-operative cryoablation (cryo) and/or Ipilimumab (Ipi).

artículo científico publicado en 2014

Memorial Sloan-Kettering Cancer Center experience with paclitaxel in the treatment of breast cancer.

artículo científico publicado en 1995

Memorial Sloan-Kettering Cancer Center experience with paclitaxel in the treatment of breast cancer: from advanced disease to adjuvant therapy.

artículo científico publicado en 1995

Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival

artículo científico publicado en 2014

Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .

artículo científico publicado en 2014

MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer

artículo científico publicado en 2011

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

artículo científico publicado en 2000

Modulation of Hsp90 function by ansamycins sensitizes breast cancer cells to chemotherapy-induced apoptosis in an RB- and schedule-dependent manner. See: E. A. Sausville, Combining cytotoxics and 17-allylamino, 17-demethoxygeldanamycin: sequence and

artículo científico publicado en 2001

Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact

artículo científico publicado en 2017

Multifocal/Multicentric Ipsilateral Invasive Breast Carcinomas with Similar Histology: Is Multigene Testing of All Individual Foci Necessary?

artículo científico publicado en 2018

N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties

artículo científico publicado en 2013

Nasal Septum Perforation in a Bevacizumab-Treated Patient with Metastatic Breast Cancer

Natural history of more than 20 years of node-positive primary breast carcinoma treated with cyclophosphamide, methotrexate, and fluorouracil-based adjuvant chemotherapy: a study by the Cancer and Leukemia Group B.

artículo científico publicado en 2003

Ninety-six-hour paclitaxel infusion after progression during short taxane exposure: a phase II pharmacokinetic and pharmacodynamic study in metastatic breast cancer

scientific article published on 01 June 1996

Novel patterns of genome rearrangement and their association with survival in breast cancer

artículo científico publicado en 2006

Occult Axillary Node Metastases in Breast Cancer Are Prognostically Significant: Results in 368 Node-Negative Patients With 20-Year Follow-Up

article by Lee K. Tan et al published 10 April 2008 in Journal of Clinical Oncology

Optimization of conditions for ex vivo expansion of CD34+ cells from patients with stage IV breast cancer ⬇️

artículo científico publicado el 15 de noviembre de 1994

Optimizing chemotherapy dose and schedule by Norton-Simon mathematical modeling

artículo científico publicado en 2010

Oral gossypol in the treatment of patients with refractory metastatic breast cancer: a phase I/II clinical trial.

artículo científico publicado en 2001

Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers

artículo científico publicado en 2002

PAM50 gene signatures and breast cancer prognosis with adjuvant anthracycline- and taxane-based chemotherapy: correlative analysis of C9741 (Alliance).

artículo científico publicado en 2016

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

artículo científico publicado en 2017

Paclitaxel for breast cancer: the Memorial Sloan-Kettering Cancer Center experience.

artículo científico publicado en 1997

Pathologic Complete Response with Neoadjuvant Doxorubicin and Cyclophosphamide Followed by Paclitaxel with Trastuzumab and Pertuzumab in Patients with HER2-Positive Early Stage Breast Cancer: A Single Center Experience

artículo científico publicado en 2017

Patterns of toxicity in older patients with breast cancer receiving adjuvant chemotherapy

artículo científico publicado en 2005

Pharmacokinetics and tolerability of exemestane in combination with raloxifene in postmenopausal women with a history of breast cancer

artículo científico publicado en 2007

Pharmacokinetics and toxicity of weekly docetaxel in older patients

artículo científico publicado en 2006

Phase 2 trial of a novel capecitabine dosing schedule in combination with bevacizumab for patients with metastatic breast cancer.

artículo científico publicado en 2011

Phase I and pharmacologic study of paclitaxel administered weekly in patients with relapsed ovarian cancer

scientific article published on 01 January 1997

Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.

artículo científico publicado en 2000

Phase I study of a novel capecitabine schedule based on the Norton-Simon mathematical model in patients with metastatic breast cancer

artículo científico publicado en 2008

Phase I study of a third-generation selective estrogen receptor modulator, LY353381.HCL, in metastatic breast cancer

artículo científico publicado en 2001

Phase I study of escalating doses of edatrexate in combination with paclitaxel in patients with metastatic breast cancer

artículo científico publicado en 1999

Phase I trial of granulocyte-macrophage colony-stimulating factor plus high-dose cyclophosphamide given every 2 weeks: a Cancer and Leukemia Group B study

scientific article published on 01 August 1993

Phase II Study of Paclitaxel and Dasatinib in Metastatic Breast Cancer.

artículo científico publicado en 2018

Phase II and pharmacologic study of docetaxel as initial chemotherapy for metastatic breast cancer

artículo científico publicado en 1996

Phase II study of celecoxib and trastuzumab in metastatic breast cancer patients who have progressed after prior trastuzumab-based treatments.

artículo científico publicado en 2004

Phase II study of feasibility of dose-dense FEC followed by alternating weekly taxanes in high-risk, four or more node-positive breast cancer

artículo científico publicado en 2004

Phase II study of paclitaxel given once per week along with trastuzumab and pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer

artículo científico publicado en 2014

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

artículo científico publicado en 1996

Phase II trial of a novel capecitabine dosing schedule in combination with lapatinib for the treatment of patients with HER2-positive metastatic breast cancer.

artículo científico publicado en 2011

Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer

artículo científico publicado en 2011

Phase III double-blind, placebo-controlled, prospective randomized trial of adjuvant tamoxifen vs. tamoxifen and fenretinide in postmenopausal women with positive receptors (EB193): an intergroup trial coordinated by the Eastern Cooperative Oncology

artículo científico publicado en 2010

Phase III study of cyclophosphamide, doxorubicin, and fluorouracil (CAF) plus leucovorin versus CAF for metastatic breast cancer: Cancer and Leukemia Group B 9140.

artículo científico publicado en 2003

Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer

artículo científico

Postsurgical adjuvant chemotherapy of stage II breast carcinoma with or without crossover to a non-cross-resistant regimen: a Cancer and Leukemia Group B study

artículo científico publicado en 1996

Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy

artículo científico publicado en 2011

Pre-operative immunotherapy with tumor cryoablation (cryo) plus ipilimumab (ipi) induces potentially favorable systemic and intratumoral immune effects in early stage breast cancer (ESBC) patients

artículo científico publicado en 2015

Prediction of prognosis in primary breast cancer by detection of a high molecular weight mucin-like antigen using monoclonal antibodies DF3, F36/22, and CU18: a Cancer and Leukemia Group B study

artículo científico publicado en 1991

Predictive factor for the response to adjuvant therapy with emphasis in breast cancer

artículo científico publicado en 2001

Preliminary experience with paclitaxel (Taxol) plus recombinant human granulocyte colony-stimulating factor in the treatment of breast cancer

artículo científico publicado el 1 de agosto de 1993

Prognostic Impact of 21-Gene Recurrence Score in Patients With Stage IV Breast Cancer: TBCRC 013

artículo científico publicado en 2016

Prolonged dose-dense epirubicin and cyclophosphamide followed by paclitaxel in breast cancer is feasible.

artículo científico publicado en 2008

Prospective Exploratory Analysis of the Association Between Tumor Response, Quality of Life, and Expenditures Among Patients Receiving Paclitaxel Monotherapy for Refractory Metastatic Breast Cancer

article

Prospective, randomized comparison of high-dose chemotherapy with stem-cell support versus intermediate-dose chemotherapy after surgery and adjuvant chemotherapy in women with high-risk primary breast cancer: a report of CALGB 9082, SWOG 9114, and N

artículo científico publicado en 2005

Psychological symptoms and disease-free and overall survival in women with stage II breast cancer. Cancer and Leukemia Group B.

artículo científico publicado en 1996

Racial differences in clinical outcomes from metastatic breast cancer: a pooled analysis of CALGB 9342 and 9840--Cancer and Leukemia Group B.

artículo científico publicado en 2008

Radiation pneumonitis in breast cancer patients treated with taxanes: does sequential radiation therapy lower the risk?

artículo científico publicado en 2005

Randomised trial of expressive writing for distressed metastatic breast cancer patients

artículo científico publicado en 2011

Randomized Phase III Trial of Weekly Compared With Every-3-Weeks Paclitaxel for Metastatic Breast Cancer, With Trastuzumab for all HER-2 Overexpressors and Random Assignment to Trastuzumab or Not in HER-2 Nonoverexpressors: Final Results of Cancer an

article

Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and Leu

article

Randomized Trial of Standard Adjuvant Chemotherapy Regimens Versus Capecitabine in Older Women With Early Breast Cancer: 10-Year Update of the CALGB 49907 Trial

artículo científico publicado en 2019

Randomized phase II trial of weekly vs. every 2 weeks vs. every 3 weeks nanoparticle albumin-bound paclitaxel with bevacizumab as first-line chemotherapy for metastatic breast cancer

artículo científico publicado en 2013

Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17.

artículo científico publicado en 2005

Rare de novo germline copy-number variation in testicular cancer

artículo científico publicado en 2012

Re: "We may be lost, but we're sure makin' good time"

scientific article published on 01 January 1994

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts ⬇️

artículo científico publicado el 1 de julio de 1998

Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer

artículo científico publicado en 1996

Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas

artículo científico publicado en 2018

Refining the origins of breast cancer

scientific article published on 01 December 1995

Reply to S. Mahesh

artículo científico

Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation

artículo científico publicado en 2003

Response to dual HER2 blockade in a patient with HER3-mutant metastatic breast cancer

artículo científico publicado en 2015

Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation-Negative Hereditary Breast Cancer Families

artículo científico publicado en 2005

Risk-Reducing Salpingo-Oophorectomy in Women With a BRCA1 or BRCA2 Mutation

Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study

artículo científico publicado en 2008

Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation

artículo científico publicado en 2002

Road Map to Safe and Well-Designed De-escalation Trials of Systemic Adjuvant Therapy for Solid Tumors

artículo científico publicado en 2020

Role of anthracyclines in the treatment of early breast cancer

artículo científico publicado en 2009

SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers

artículo científico publicado en 2008

Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642.

artículo científico publicado en 1999

Screening chest imaging studies are not effective in the follow-up of breast cancer patients.

artículo científico publicado en 2003

Self-seeding in cancer

artículo científico

Sequential adjuvant therapy: the Memorial Sloan-Kettering Cancer Center experience

artículo científico publicado en 1996

Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate

article

Serum metabolomic profiles evaluated after surgery may identify patients with oestrogen receptor negative early breast cancer at increased risk of disease recurrence. Results from a retrospective study

artículo científico publicado en 2014

Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia

artículo científico publicado en 2003

Simultaneous dose escalation and schedule intensification of carboplatin-based chemotherapy using peripheral blood progenitor cells and filgrastim: a phase I trial.

artículo científico publicado en 1994

Six cycles of doxorubicin and cyclophosphamide or Paclitaxel are not superior to four cycles as adjuvant chemotherapy for breast cancer in women with zero to three positive axillary nodes: Cancer and Leukemia Group B 40101.

artículo científico publicado en 2012

Slug promotes survival during metastasis through suppression of Puma-mediated apoptosis

artículo científico publicado en 2014

Social support as a buffer to the psychological impact of stressful life events in women with breast cancer

article

Somatic mutations in leukocytes infiltrating primary breast cancers

artículo científico publicado en 2015

Sources of anticipatory emotional distress in women receiving chemotherapy for breast cancer.

artículo científico publicado en 1995

Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte Carlo mathematical model.

artículo científico publicado en 2013

Subcutaneously Administered Recombinant Human Interleukin-2 and Interferon Alfa-2a for Advanced Breast Cancer: A Phase II study of the Cancer and Leukemia Group B (CALGB 9041)

scientific article published on 01 January 2004

TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition

artículo científico publicado en 2013

TNF is a key cytokine mediating neutrophil cytotoxic activity in breast cancer patients

artículo científico publicado en 2016

Taxol (paclitaxel) plus recombinant human granulocyte colony-stimulating factor in the treatment of metastatic breast cancer

artículo científico publicado en 1994

The 21-Gene Recurrence Score in Male Breast Cancer

artículo científico publicado en 2018

The 21-gene recurrence score in special histologic subtypes of breast cancer with favorable prognosis

artículo científico publicado en 2017

The 6q22.33 locus and breast cancer susceptibility

artículo científico publicado en 2009

The AURORA initiative for metastatic breast cancer

artículo científico publicado en 2014

The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women

artículo científico publicado en 1999

The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women: Results From the MORE Randomized Trial

The Epidermal Growth Factor Receptor Modulates the Interaction of E-cadherin with the Actin Cytoskeleton ⬇️

artículo científico publicado el 10 de abril de 1998

The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis

artículo científico publicado en 2013

The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers

artículo científico publicado en 2018

The Landscape of Somatic Genetic Alterations in Metaplastic Breast Carcinomas

artículo científico publicado en 2017

The MORE trial: multiple outcomes for raloxifene evaluation--breast cancer as a secondary end point: implications for prevention.

artículo científico publicado en 2001

The NHL-15 protocol for aggressive non-Hodgkin's lymphomas: a sequential dose-dense, dose-intense regimen of doxorubicin, vincristine and high-dose cyclophosphamide

artículo científico publicado en 2004

The Norton-Simon hypothesis: designing more effective and less toxic chemotherapeutic regimens

artículo científico publicado en 2006

The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%

The concept of mathematically optimised dose-scheduling as applied to the adjuvant chemotherapy of primary breast cancer: theory and recent results

article by Larry Norton published January 2008 in EJC supplements

The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation

artículo científico publicado en 1999

The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study

artículo científico publicado en 2014

The genetic landscape of breast carcinomas with neuroendocrine differentiation

artículo científico publicado en 2016

The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study

artículo científico publicado en 2015

The safety of dose-dense doxorubicin and cyclophosphamide followed by paclitaxel with trastuzumab in HER-2/neu overexpressed/amplified breast cancer.

artículo científico publicado en 2008

Theoretical concepts and the emerging role of taxanes in adjuvant therapy

artículo científico publicado en 2001

Therapeutic leukapheresis for hyperleukocytosis in acute myelocytic leukemia

artículo científico publicado en 1983

Timing of radiotherapy in the treatment of early-stage breast cancer

artículo científico publicado en 1993

Toxicity of Older and Younger Patients Treated With Adjuvant Chemotherapy for Node-Positive Breast Cancer: The Cancer and Leukemia Group B Experience

article

Translating mathematical modeling of tumor growth patterns into novel therapeutic approaches for breast cancer

artículo científico

Trimetrexate in untreated and previously treated patients with metastatic breast cancer: A cancer and leukemia group b study ⬇️

artículo científico publicado el 1 de enero de 1991

Troponin I and C-Reactive Protein Are Commonly Detected in Patients with Breast Cancer Treated with Dose-Dense Chemotherapy Incorporating Trastuzumab and Lapatinib

Tumor entrained neutrophils inhibit seeding in the premetastatic lung

artículo científico publicado en 2011

Tumor marker utility grading system: a framework to evaluate clinical utility of tumor markers

artículo científico publicado en 1996

Tumor self-seeding by circulating cancer cells

artículo científico publicado en 2009

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

artículo científico publicado en 2001

Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21.

artículo científico publicado en 2000

Weekly paclitaxel with trastuzumab and pertuzumab in patients with HER2-overexpressing metastatic breast cancer: overall survival and updated progression-free survival results from a phase II study

artículo científico publicado en 2016

Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification.

artículo científico publicado en 2001

Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples

artículo científico publicado en 2017

p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis

artículo científico publicado en 2012

p53 Expression in node-positive breast cancer patients: results from the Cancer and Leukemia Group B 9344 Trial (159905).

artículo científico publicado en 2011

p53 in node-negative breast carcinoma: an immunohistochemical study of epidemiologic risk factors, histologic features, and prognosis

artículo científico publicado en 1995

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