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Lista de obras de Mark E. Hahn

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptotic cell death and cytochrome P4501A expression in developing Fundulus heteroclitus embryos

artículo científico publicado en 2001

A fish hepatoma cell line (PLHC-1) as a tool to study cytotoxicity and CYP1A induction properties of cellulose and wood chip extracts

artículo científico publicado en 1998

A ligand for the aryl hydrocarbon receptor isolated from lung

artículo científico publicado en 2002

A reverse transcription-polymerase chain reaction (RT-PCR) approach for cloning Ah receptors from diverse vertebrate species: Partial sequence of an Ah receptor from the teleost Fundulus heteroclitus

article published in 1996

AHR1B, a new functional aryl hydrocarbon receptor in zebrafish: tandem arrangement of ahr1b and ahr2 genes

artículo científico publicado en 2005

Alan Poland, MS, MD: 1940-2020 Poisons as Probes of Biological Function

scientific article published on 21 December 2020

Amino acid sequence of the ligand-binding domain of the aryl hydrocarbon receptor 1 predicts sensitivity of wild birds to effects of dioxin-like compounds

artículo científico publicado en 2012

An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2015

An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone binding.

artículo científico publicado en 2001

Aryl hydrocarbon receptor (AHR) in the cnidarian Nematostella vectensis: comparative expression, protein interactions, and ligand binding

artículo científico publicado en 2013

Aryl hydrocarbon receptor function in early vertebrates:

artículo científico publicado en 1998

Aryl hydrocarbon receptor polymorphisms and dioxin resistance in Atlantic killifish (Fundulus heteroclitus).

artículo científico publicado en 2004

Aryl hydrocarbon receptors: diversity and evolution

artículo científico publicado en 2002

Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs)

scientific journal article

Biochemical warfare on the reef: the role of glutathione transferases in consumer tolerance of dietary prostaglandins

artículo científico publicado en 2010

Biological activity and physicochemical parameters of marine halogenated natural products 2,3,3',4,4',5,5'-heptachloro-1'-methyl-1,2'-bipyrrole and 2,4,6-tribromoanisole.

artículo científico publicado en 2005

Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner

artículo científico publicado en 2016

Biomarkers and bioassays for detecting dioxin-like compounds in the marine environment

artículo científico publicado en 2002

Blubber morphology in wild bottlenose dolphins (Tursiops truncatus) from the Southeastern United States: Influence of geographic location, age class, and reproductive state

artículo científico publicado en 2008

Brominated flame retardants and organochlorine contaminants in winter flounder, harp and hooded seals, and North Atlantic right whales from the Northwest Atlantic Ocean

artículo científico publicado en 2010

Burnt Plastic (Pyroplastic) from the M/V <i>X-Press Pearl</i> Ship Fire and Plastic Spill Contain Compounds That Activate Endocrine and Metabolism-Related Human and Fish Transcription Factors

artículo científico publicado en 2024

CHRONIC RETENE EXPOSURE CAUSES SUSTAINED INDUCTION OF CYP1A ACTIVITY AND PROTEIN IN RAINBOW TROUT (ONCORHYNCHUS MYKISS)

article by Nuno M. Fragoso et al published 1998 in Environmental Toxicology and Chemistry

Casting a wide net: use of diverse model organisms to advance toxicology

artículo científico publicado en 2020

Catalytic and Immunochemical Characterization of Hepatic Microsomal Cytochromes P450 in Beluga Whale (Delphinapterus leucas)

scientific article published on 01 May 1994

Chapter 7 Xenobiotic receptors in fish: Structural and functional diversity and evolutionary insights

scientific article published in 2005

Characterization of the Aryl Hydrocarbon Receptor (AhR) Pathway in Anabas testudineus and Mechanistic Exploration of the Reduced Sensitivity of AhR2a

artículo científico publicado en 2019

Cloning and analysis of the CYP1A promoter from the atlantic killifish (Fundulus heteroclitus).

artículo científico publicado en 2004

Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor

artículo científico publicado en 2013

Comparison of two bioassays, a fish liver cell line (PLHC-1) and a midge (Chironomus riparius), in monitoring freshwater sediments

Cytochrome P450 diversity and induction by gorgonian allelochemicals in the marine gastropod Cyphoma gibbosum

artículo científico publicado en 2010

Cytochrome P4501A induction and inhibition by 3,3′,4,4′-tetrachlorobiphenyl in an Ah receptor-containing fish hepatoma cell line (PLHC-1)

scholarly article by Mark E. Hahn et al published August 1993 in Aquatic Toxicology

Cytochrome P4501A induction and porphyrin accumulation in PLHC-1 fish cells exposed to sediment and oil shale extracts

artículo científico publicado en 2000

Cytochrome P4501A induction in avian hepatocyte cultures: a promising approach for predicting the sensitivity of avian species to toxic effects of halogenated aromatic hydrocarbons

artículo científico publicado en 1996

Cytochrome P4501A1 expression, polychlorinated biphenyls and hydroxylated metabolites, and adipocyte size of bottlenose dolphins from the Southeast United States

artículo científico publicado en 2007

Cytochromes P450 (CYP) in the Poeciliopsis lucida hepatocellular carcinoma cell line (PLHC-1): dose- and time-dependent glucocorticoid potentiation of CYP1A induction without induction of CYP3A.

artículo científico publicado en 1996

Delayed effects of developmental exposure to low levels of the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB126) on adult zebrafish behavior

artículo científico publicado en 2015

Determination of individual porphyrins in rodent urine using high-performance liquid chromatography following clean-up by anion-exchange chromatography

scientific article published on 01 February 1991

Developing tools for risk assessment in protected species: Relative potencies inferred from competitive binding of halogenated aromatic hydrocarbons to aryl hydrocarbon receptors from beluga (Delphinapterus leucas) and mouse

artículo científico publicado en 2010

Development and characterization of polyclonal antibodies against the aryl hydrocarbon receptor protein family (AHR1, AHR2, and AHR repressor) of Atlantic killifish Fundulus heteroclitus

artículo científico publicado en 2005

Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model

artículo científico publicado en 2008

Developmental Exposure to Domoic Acid Disrupts Startle Response Behavior and Circuitry in Zebrafish

artículo científico publicado en 2021

Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in zebrafish (Danio rerio)

scientific article published on 01 February 2019

Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish

artículo científico publicado en 2013

Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio

artículo científico publicado en 2013

Differential sensitivity to pro-oxidant exposure in two populations of killifish (Fundulus heteroclitus)

artículo científico publicado en 2013

Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2009

Divergent Forms of Pyroplastic: Lessons Learned from the M/V X-Press Pearl Ship Fire

Diversity as Opportunity: Insights from 600 Million Years of AHR Evolution

Duplicate aryl hydrocarbon receptor repressor genes (ahrr1 and ahrr2) in the zebrafish Danio rerio: structure, function, evolution, and AHR-dependent regulation in vivo

artículo científico publicado en 2005

Editor’s Note

Effect of hexachlorobenzene on the specific binding of 2,3,7,8,-TCDD to the hepatic receptor

Effects of ortho- and non-ortho-substituted polychlorinated biphenyl congeners on the hepatic monooxygenase system in scup (Stenotomus chrysops)

artículo científico publicado en 1989

Effects of short-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on microRNA expression in zebrafish embryos

artículo científico publicado en 2012

Estrogen receptor-related receptors in the killifish Fundulus heteroclitus: diversity, expression, and estrogen responsiveness

artículo científico publicado en 2006

Estrogen responses in killifish (Fundulus heteroclitus) from polluted and unpolluted environments are site- and gene-specific

artículo científico publicado en 2010

Evolutionary concepts can benefit both fundamental research and applied research in toxicology (A comment on Brady et al. 2017)

Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories

artículo científico publicado en 2003

Expression of P-glycoprotein in killifish (Fundulus heteroclitus) exposed to environmental xenobiotics

artículo científico publicado en 2002

Fire and Oil Led to Complex Mixtures of PAHs on Burnt and Unburnt Plastic during the M/V <i>X-Press Pearl</i> Disaster

artículo científico publicado en 2023

Fish Models in Toxicology

scientific article published on 01 January 2007

Functional Characterization and Evolutionary History of Two Aryl Hydrocarbon Receptor Isoforms (AhR1 and AhR2) from Avian Species

artículo científico publicado en 2007

Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio)

artículo científico publicado en 2013

Functional characterization of two AH receptors in the marine fish, Fundulus heteroclitus: TCDD and DNA binding and tissue-specific expression

Functional diversity of vertebrate ARNT proteins: identification of ARNT2 as the predominant form of ARNT in the marine teleost, Fundulus heteroclitus

artículo científico

Functional properties of the four Atlantic salmon (Salmo salar) aryl hydrocarbon receptor type 2 (AHR2) isoforms

artículo científico publicado en 2007

Fundulus as the premier teleost model in environmental biology: opportunities for new insights using genomics

artículo científico publicado en 2007

Gene knockdown by morpholino-modified oligonucleotides in the zebrafish (Danio rerio) model: applications for developmental toxicology

artículo científico publicado en 2012

Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists

artículo científico publicado en 2010

Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats

artículo científico publicado en 2014

Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo

artículo científico publicado en 2013

Gonadal feminization and halogenated environmental contaminants in common terns (Sterna hirundo): evidence that ovotestes in male embryos do not persist to the prefledgling stage

artículo científico publicado en 2003

Halogenated aromatic hydrocarbon-mediated porphyrin accumulation and induction of cytochrome P4501A in chicken embryo hepatocytes

artículo científico publicado en 1997

Identification and functional characterization of hypoxia-inducible factor 2alpha from the estuarine teleost, Fundulus heteroclitus: interaction of HIF-2alpha with two ARNT2 splice variants

artículo científico publicado en 2002

Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production.

artículo científico publicado en 2014

Immunohistochemical localization of environmentally induced cytochrome P450IA1 in multiple organs of the marine teleost Stenotomus chrysops (Scup).

artículo científico publicado en 1991

In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo

artículo científico publicado en 2014

Induction of CYP1A and porphyrin accumulation in fish hepatoma cells (PLHC-1) exposed to sediment or water from a PCB-contaminated lake (Lake Kernaala, Finland)

article

Induction of cytochrome P-450E (P-450IA1) by 2,3,7,8-tetrachlorodibenzofuran (2,3,7,8-TCDF) in the marine fish scup (Stenotomus chrysops)

Integrating Monitoring and Genetic Methods To Infer Historical Risks of PCBs and DDE to Common and Roseate Terns Nesting Near the New Bedford Harbor Superfund Site (Massachusetts, USA).

artículo científico publicado en 2016

Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein

artículo científico publicado en 2009

Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro and in vivo,

scientific article published in 1989

Interaction of hexachlorobenzene with the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro and in vivo. Evidence that hexachlorobenzene is a weak Ah receptor agonist

artículo científico publicado en 1989

Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species

artículo científico publicado en 2008

Knockdown of a zebrafish aryl hydrocarbon receptor repressor (AHRRa) affects expression of genes related to photoreceptor development and hematopoiesis

artículo científico publicado en 2014

Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): characterization of the Ah receptor and the role of CYP1A inhibition

artículo científico publicado en 1998

Mechanistic basis of resistance to PCBs in Atlantic tomcod from the Hudson River

artículo científico publicado en 2011

Mechanistic research in aquatic toxicology: Perspectives and future directions ⬇️

artículo científico publicado el 12 de junio de 2011

Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a

artículo científico publicado en 2020

Molecular characterization and tissue-specific expression of the aryl hydrocarbon receptor in the Beluga, Delphinapterus leucas

Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family ⬇️

artículo científico publicado el 9 de diciembre de 1997

NATURALLY PRODUCED HALOGENATED DIMETHYL BIPYRROLES BIND TO THE ARYL HYDROCARBON RECEPTOR AND INDUCE CYTOCHROME P4501A AND PORPHYRIN ACCUMULATION IN CHICKEN EMBRYO HEPATOCYTES

Naturally occurring marine brominated indoles are aryl hydrocarbon receptor ligands/agonists

artículo científico publicado en 2015

Neuroanatomy of the subadult and fetal brain of the Atlantic white-sided dolphin (Lagenorhynchus acutus) from in situ magnetic resonance images

artículo científico publicado en 2007

Nrf2 and Nrf2-related proteins in development and developmental toxicity: Insights from studies in zebrafish (Danio rerio)

artículo científico publicado en 2015

Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).

artículo científico publicado en 2011

Organohalogen contaminants and metabolites in cerebrospinal fluid and cerebellum gray matter in short-beaked common dolphins and Atlantic white-sided dolphins from the western North Atlantic

artículo científico publicado en 2009

Photoaffinity Labeling of the Ah Receptor: Phylogenetic Survey of Diverse Vertebrate and Invertebrate Species

article

Phylogenetic distribution of the Ah receptor in non-mammalian species: implications for dioxin toxicity and Ah receptor evolution

scholarly article by Mark E. Hahn & John J. Stegeman published October 1992 in Chemosphere

Proteomic identification, cDNA cloning and enzymatic activity of glutathione S-transferases from the generalist marine gastropod, Cyphoma gibbosum

artículo científico publicado en 2008

RAPID ASSESSMENT OF INDUCED CYTOCHROME P4501A PROTEIN AND CATALYTIC ACTIVITY IN FISH HEPATOMA CELLS GROWN IN MULTIWELL PLATES: RESPONSE TO TCDD, TCDF, AND TWO PLANAR PCBS

Reduced cytochrome P4501A activity and recovery from oxidative stress during subchronic benzo[a]pyrene and benzo[e]pyrene treatment of rainbow trout

artículo científico publicado en 2011

Regulation of Ahr signaling by Nrf2 during development: Effects of Nrf2a deficiency on PCB126 embryotoxicity in zebrafish (Danio rerio)

artículo científico publicado en 2015

Regulation of Cytochrome P4501A1 in Teleosts: Sustained Induction of CYP1A1 mRNA, Protein, and Catalytic Activity by 2,3,7,8-Tetrachlorodibenzofuran in the Marine Fish Stenotomus chrysops

artículo científico publicado en 1994

Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor

artículo científico publicado en 2008

Regulation of pregnane-X-receptor, CYP3A and P-glycoprotein genes in the PCB-resistant killifish (Fundulus heteroclitus) population from New Bedford Harbor

artículo científico publicado en 2014

Regulatory interactions among three members of the vertebrate aryl hydrocarbon receptor family: AHR repressor, AHR1, and AHR2.

artículo científico publicado en 2001

Relationships among the cell cycle, cell proliferation, and aryl hydrocarbon receptor expression in PLHC-1 cells

artículo científico publicado en 2002

Relative Contributions of Affinity and Intrinsic Efficacy to Aryl Hydrocarbon Receptor Ligand Potency

artículo científico publicado en 2000

Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator

artículo científico publicado en 2008

Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3',4,4',5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2007

Role of DNA methylation of AHR1 and AHR2 promoters in differential sensitivity to PCBs in Atlantic Killifish, Fundulus heteroclitus

artículo científico publicado en 2010

Sequence and In Vitro Function of Chicken, Ring-Necked Pheasant, and Japanese Quail AHR1 Predict In Vivo Sensitivity to Dioxins

artículo científico publicado en 2012

Sequence and functional characterization of hypoxia-inducible factors, HIF1α, HIF2αa, and HIF3α, from the estuarine fish, Fundulus heteroclitus

artículo científico publicado en 2016

Serum withdrawal leads to reduced aryl hydrocarbon receptor expression and loss of cytochrome P4501A inducibility in PLHC-1 cells

artículo científico publicado en 2002

Species-specific relative AHR1 binding affinities of 2,3,4,7,8-pentachlorodibenzofuran explain avian species differences in its relative potency

artículo científico publicado en 2014

Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis

artículo científico publicado en 2013

Structural and Functional Diversification of AHRs during Metazoan Evolution

Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus).

artículo científico publicado en 2014

The African coelacanth genome provides insights into tetrapod evolution

artículo científico publicado en 2013

The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model

artículo científico publicado en 2020

The Ah receptor in marine animals: phylogenetic distribution and relationship to cytochrome P4501A inducibility

scholarly article by Mark E. Hahn et al published January 1992 in Marine Environmental Research

The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factor

artículo científico publicado en 2009

The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells

artículo científico publicado en 2005

The aryl hydrocarbon receptor in early vertebrates

The aryl hydrocarbon receptor: A comparative perspective

artículo científico publicado en 1998

The evolution of aryl hydrocarbon signaling proteins: diversity of ARNT isoforms among fish species.

artículo científico publicado en 2000

The genome of the sea urchin Strongylocentrotus purpuratus

artículo científico publicado en 2006

The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish ⬇️

artículo científico publicado en 2016

The liver transcriptome of suckermouth armoured catfish (Pterygoplichthys anisitsi, Loricariidae): Identification of expansions in defensome gene families

artículo científico publicado en 2017

The molecular basis for differential dioxin sensitivity in birds: role of the aryl hydrocarbon receptor

artículo científico publicado en 2006

The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals

artículo científico publicado en 2010

The role of polycyclic aromatic hydrocarbon metabolism in dimethylbenz[a]anthracene-induced pre-B lymphocyte apoptosis.

artículo científico publicado en 1999

The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2014

The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish

artículo científico publicado en 2009

The zebrafish (Danio rerio) aryl hydrocarbon receptor type 1 is a novel vertebrate receptor

artículo científico publicado en 2002

Towards molecular understanding of species differences in dioxin sensitivity: initial characterization of Ah receptor cDNAs in birds and an amphibian

artículo científico publicado en 2000

Transcriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site

artículo científico publicado en 2011

Two forms of aryl hydrocarbon receptor type 2 in rainbow trout (Oncorhynchus mykiss). Evidence for differential expression and enhancer specificity.

artículo científico publicado en 1999

Two zebrafish alcohol dehydrogenases share common ancestry with mammalian class I, II, IV, and V alcohol dehydrogenase genes but have distinct functional characteristics

artículo científico publicado en 2004

Uptake of waterborne 3,3′,4,4′-tetrachlorobiphenyl and organ and cell-specific induction of cytochrome P4501A in adult and larval fathead minnow Pimephales promelas

Uroporphyrin accumulation associated with cytochrome P4501A induction in fish hepatoma cells exposed to aryl hydrocarbon receptor agonists, including 2,3,7,8-tetrachlorodibenzo-p-dioxin and planar chlorobiphenyls

artículo científico publicado en 1996

Volumetric neuroimaging of the atlantic white-sided dolphin (Lagenorhynchus acutus) brain from in situ magnetic resonance images

artículo científico publicado en 2008

When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Fundulus heteroclitus) populations.

artículo científico publicado en 2017

cDNA cloning and characterization of an aryl hydrocarbon receptor from the harbor seal (Phoca vitulina): a biomarker of dioxin susceptibility?

artículo científico publicado en 2002

cDNA cloning of an aryl hydrocarbon receptor from Baikal seals (Phoca sibirica).

artículo científico publicado en 2002

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