Lista de obras - Paolo Manunta - Dominio Público Uruguay

A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.

artículo científico publicado en 2013

A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia

artículo científico publicado en 2015

A new antihypertensive agent that antagonizes the prohypertensive effect of endogenous ouabain and adducin

artículo científico publicado en 2006

A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain

artículo científico publicado en 2014

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

ACE and α-Adducin Polymorphism as Markers of Individual Response to Diuretic Therapy

article

ADDing a piece to the puzzle of cognition in schizophrenia.

artículo científico publicado en 2015

Adducin in essential hypertension

artículo científico publicado en 1998

Adducin polymorphisms and the treatment of hypertension

artículo científico publicado en 2007

Adducin, Renal Intermediate Phenotypes, and Hypertension

Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies

artículo científico publicado en 2010

Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients.

artículo científico publicado en 1998

Angiotensin-converting enzyme I/D and alpha-adducin Gly460Trp polymorphisms: from angiotensin-converting enzyme activity to cardiovascular outcome

artículo científico publicado en 2007

Are Retinal Microvascular Phenotypes Associated With the 1675G/A Polymorphism in the Angiotensin II Type-2 Receptor Gene?

article

Are the new single nucleotide polymorphisms (SNPs) relevant for hypertensive populations?

artículo científico publicado en 2002

Arterial properties in relation to genetic variation in alpha-adducin and the renin-angiotensin system in a White population

artículo científico publicado en 2008

Arterial properties in relation to genetic variations in the adducin subunits in a white population

artículo científico publicado en 2008

Association Between Arterial Properties and Renal Sodium Handling in a General Population

article

Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.

artículo científico publicado en 2006

Association of echocardiographic left ventricular structure with the ACE D/I polymorphism: a meta-analysis

artículo científico publicado en 2011

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Beta-adducin and sodium-calcium exchanger 1 gene variants are associated with systemic lupus erythematosus and lupus nephritis

scientific article published on 05 June 2015

Cardiac glycosides and cardiomyopathy

artículo científico publicado en 2006

Changes in mass and energy transfer between the canopy and the atmosphere: model development and testing with a free-air CO2 enrichment (FACE) experiment

artículo científico publicado en 2002

Clinical impact of adducin polymorphism

artículo científico publicado en 2009

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension

artículo científico publicado en 2007

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

artículo científico publicado en 2013

Coronary risk in relation to genetic variation in MEOX2 and TCF15 in a Flemish population

artículo científico publicado en 2015

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

artículo científico publicado en 2014

Deciphering Variability of PKD1 and PKD2 in an Italian Cohort of 643 Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD).

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Different effects of marinobufagenin and endogenous ouabain

artículo científico publicado en 2004

Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity

artículo científico publicado en 2008

Efficacy and tolerability of doxazosin alone or in combination with chlorthalidone in essential hypertension

Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases

article

Endogenous Ouabain: An Old Cardiotonic Steroid as a New Biomarker of Heart Failure and a Predictor of Mortality after Cardiac Surgery.

artículo científico publicado en 2015

Endogenous cardiotonic steroids in kidney failure: a review and an hypothesis

artículo científico publicado en 2015

Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension

artículo científico publicado en 2016

Endogenous ouabain and cardiomyopathy in dialysis patients

artículo científico publicado en 2007

Endogenous ouabain and hemodynamic and left ventricular geometric patterns in essential hypertension

scientific article published on 01 January 2001

Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension

artículo científico publicado en 2011

Endogenous ouabain in Ménière's disease.

artículo científico publicado en 2010

Endogenous ouabain in cardiovascular function and disease

artículo científico publicado en 2009

Endogenous ouabain in renal Na(+) handling and related diseases

artículo científico publicado en 2010

Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis

artículo científico publicado en 1996

Endogenous ouabain: a link between sodium intake and hypertension

artículo científico publicado en 2011

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.

artículo científico publicado en 2011

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

artículo científico publicado en 2017

Genetic burden of common variants in progressive and bout-onset multiple sclerosis

artículo científico publicado en 2013

Genetic evidence of assortative mating in humans

scholarly article

Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci.

artículo científico publicado en 2017

Genetics of essential hypertension: from families to genes

artículo científico publicado en 2002

Genetics of ion homeostasis in Ménière's Disease.

artículo científico publicado en 2016

Genetics of primary hypertension: the clinical impact of adducin polymorphisms.

artículo científico publicado en 2010

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

artículo científico publicado en 2016

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

artículo científico publicado en 2011

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

artículo científico publicado en 2013

Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers.

artículo científico publicado en 2002

Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.

artículo científico publicado en 2008

Heat wave hazard classification and risk assessment using artificial intelligence fuzzy logic

artículo científico publicado en 2013

Hypertension in High School Students: Genetic and Environmental Factors: The HYGEF Study

scientific article published on 25 November 2019

Immunoreactive endogenous ouabain primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels

article

Inactive Matrix Gla Protein Is Causally Related to Adverse Health Outcomes

article

Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathy

article

Ion Channels and Transporters in Inflammation: Special Focus on TRP Channels and TRPC6

Klotho Gene in Human Salt-Sensitive Hypertension

scientific article published on 28 January 2020

Lanosterol Synthase Gene Polymorphisms and Changes in Endogenous Ouabain in the Response to Low Sodium Intake.

artículo científico publicado en 2015

Lanosterol Synthase Genetic Variants, Endogenous Ouabain, and Both Acute and Chronic Kidney Injury

artículo científico publicado en 2019

Left ventricular geometry and endogenous ouabain in a Flemish population

article

Left ventricular radial function associated with genetic variation in the cGMP-dependent protein kinase.

artículo científico publicado en 2013

Left ventricular structure and function in relation to steroid biosynthesis genes in a white population.

artículo científico publicado en 2012

Low-salt diet and diuretic effect on blood pressure and organ damage

artículo científico publicado en 2004

MPO antibody-positive vasculitis in a patient with psoriatic arthritis and gold-induced membranous glomerulonephritis

artículo científico publicado en 1998

Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin

artículo científico publicado en 2011

MicroRNA 193b-3p as a predictive biomarker of chronic kidney disease in patients undergoing radical nephrectomy for renal cell carcinoma.

artículo científico publicado en 2016

Na+, kidney, hypertension and genes

article

OASIS-HT: design of a pharmacogenomic dose-finding study

artículo científico publicado en 2005

Ouabain Contributes to Kidney Damage in a Rat Model of Renal Ischemia-Reperfusion Injury

artículo científico publicado en 2016

Ouabain-like factor: is this the natriuretic hormone?

artículo científico publicado en 2000

Personalized Therapy of Hypertension: the Past and the Future

artículo científico publicado en 2016

Pharmacogenomics and pharmacogenetics of hypertension: update and perspectives--the adducin paradigm

artículo científico publicado en 2006

Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice

artículo científico publicado en 2020

Physiological Interaction Between α-Adducin and WNK1-NEDD4L Pathways on Sodium-Related Blood Pressure Regulation

Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension

artículo científico publicado en 1997

Polymorphisms, Hypertension and Thiazide Diuretics ⬇️

artículo científico publicado el 1 de noviembre de 2011

Predicting acute kidney injury: current status and future challenges

artículo científico

Preoperative endogenous ouabain predicts acute kidney injury in cardiac surgery patients

scientific article published on March 2013

Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1.

artículo científico publicado en 2017

Quantitative proteomics reveals novel therapeutic and diagnostic markers in hypertension.

artículo científico publicado en 2014

Recognition of markers of response to potassium-canrenoate in essential hypertension

artículo científico publicado en 1995

Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension.

artículo científico publicado en 2008

Reply: "Comment on: Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases" ⬇️

artículo científico

Role of the adducin family genes in human essential hypertension

artículo científico publicado en 2005

Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain

artículo científico publicado en 2014

SIK1 localizes with nephrin in glomerular podocytes and its polymorphism predicts kidney injury.

artículo científico publicado en 2014

Salt Sensitivity: Challenging and Controversial Phenotype of Primary Hypertension

artículo científico publicado en 2016

Salt intake and depletion increase circulating levels of endogenous ouabain in normal men.

artículo científico publicado en 2006

Salt, endogenous ouabain and blood pressure interactions in the general population

artículo científico publicado en 2003

Steroid biosynthesis and renal excretion in human essential hypertension: association with blood pressure and endogenous ouabain.

artículo científico publicado en 2009

Synergistic effect of α-adducin and ACE genes causes blood pressure changes with body sodium and volume expansion

article

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

artículo científico publicado en 2015

TRPC6 gene variants and neuropsychiatric lupus.

artículo científico publicado en 2015

Target sequencing, cell experiments, and a population study establish endothelial nitric oxide synthase (eNOS) gene as hypertension susceptibility gene

artículo científico publicado en 2013

Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach

artículo científico publicado en 2006

The -665 C>T polymorphism in the eNOS gene predicts cardiovascular mortality and morbidity in white Europeans

artículo científico publicado en 2014

The TRPC6 intronic polymorphism, associated with the risk of neurological disorders in systemic lupus erythematous, influences immune cell function

artículo científico publicado en 2018

The clinical pathway for hypertensive patient of local health unit, hospitals and general practitioners, the Milan experience

artículo científico publicado en 2011

The endogenous ouabain: molecular basis of its role in hypertension and cardiovascular complications

artículo científico publicado en 2005

The risk of nephrolithiasis is causally related to inactive matrix Gla protein, a marker of vitamin K status: a Mendelian randomization study in a Flemish population

artículo científico publicado en 2017

The role of adducin in hypertension

The young girl with renovascular hypertension of unknown origin

artículo científico publicado en 1997

Urinary neutrophil gelatinase-associated lipocalin time course during cardiac surgery.

artículo científico publicado en 2015

Xanthine oxidase gene variants and their association with blood pressure and incident hypertension: a population study

artículo científico publicado en 2016

[Psychological Assessment of a sample of women with ADPKD: quality of life, body image, anxiety and depression]

scientific article published on 01 April 2019

alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy

artículo científico publicado en 2009

cGMP-dependent protein kinase 1 polymorphisms underlie renal sodium handling impairment

artículo científico publicado en 2013

Lista de obras de Paolo Manunta

A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.

A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia

A new antihypertensive agent that antagonizes the prohypertensive effect of endogenous ouabain and adducin

A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

ACE and α-Adducin Polymorphism as Markers of Individual Response to Diuretic Therapy

ADDing a piece to the puzzle of cognition in schizophrenia.

Adducin in essential hypertension

Adducin polymorphisms and the treatment of hypertension

Adducin, Renal Intermediate Phenotypes, and Hypertension

Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies

Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients.

Angiotensin-converting enzyme I/D and alpha-adducin Gly460Trp polymorphisms: from angiotensin-converting enzyme activity to cardiovascular outcome

Are Retinal Microvascular Phenotypes Associated With the 1675G/A Polymorphism in the Angiotensin II Type-2 Receptor Gene?

Are the new single nucleotide polymorphisms (SNPs) relevant for hypertensive populations?

Arterial properties in relation to genetic variation in alpha-adducin and the renin-angiotensin system in a White population

Arterial properties in relation to genetic variations in the adducin subunits in a white population

Association Between Arterial Properties and Renal Sodium Handling in a General Population

Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension.

Association of echocardiographic left ventricular structure with the ACE D/I polymorphism: a meta-analysis

Associations of autozygosity with a broad range of human phenotypes

Beta-adducin and sodium-calcium exchanger 1 gene variants are associated with systemic lupus erythematosus and lupus nephritis

Cardiac glycosides and cardiomyopathy

Changes in mass and energy transfer between the canopy and the atmosphere: model development and testing with a free-air CO2 enrichment (FACE) experiment

Clinical impact of adducin polymorphism

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension

Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

Coronary risk in relation to genetic variation in MEOX2 and TCF15 in a Flemish population

Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Deciphering Variability of PKD1 and PKD2 in an Italian Cohort of 643 Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD).

Defining the role of common variation in the genomic and biological architecture of adult human height

Different effects of marinobufagenin and endogenous ouabain

Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity

Efficacy and tolerability of doxazosin alone or in combination with chlorthalidone in essential hypertension

Endogenous Ouabain and Related Genes in the Translation from Hypertension to Renal Diseases

Endogenous Ouabain: An Old Cardiotonic Steroid as a New Biomarker of Heart Failure and a Predictor of Mortality after Cardiac Surgery.

Endogenous cardiotonic steroids in kidney failure: a review and an hypothesis

Endogenous ouabain and aldosterone are coelevated in the circulation of patients with essential hypertension

Endogenous ouabain and cardiomyopathy in dialysis patients

Endogenous ouabain and hemodynamic and left ventricular geometric patterns in essential hypertension

Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension

Endogenous ouabain in Ménière's disease.

Endogenous ouabain in cardiovascular function and disease

Endogenous ouabain in renal Na(+) handling and related diseases

Endogenous ouabain, sodium balance and blood pressure: a review and a hypothesis

Endogenous ouabain: a link between sodium intake and hypertension

Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

Genetic burden of common variants in progressive and bout-onset multiple sclerosis

Genetic evidence of assortative mating in humans

Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci.

Genetics of essential hypertension: from families to genes

Genetics of ion homeostasis in Ménière's Disease.

Genetics of primary hypertension: the clinical impact of adducin polymorphisms.

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers.

Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.

Heat wave hazard classification and risk assessment using artificial intelligence fuzzy logic

Hypertension in High School Students: Genetic and Environmental Factors: The HYGEF Study

Immunoreactive endogenous ouabain primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels

Inactive Matrix Gla Protein Is Causally Related to Adverse Health Outcomes

Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathy

Ion Channels and Transporters in Inflammation: Special Focus on TRP Channels and TRPC6

Klotho Gene in Human Salt-Sensitive Hypertension

Lanosterol Synthase Gene Polymorphisms and Changes in Endogenous Ouabain in the Response to Low Sodium Intake.

Lanosterol Synthase Genetic Variants, Endogenous Ouabain, and Both Acute and Chronic Kidney Injury

Left ventricular geometry and endogenous ouabain in a Flemish population

Left ventricular radial function associated with genetic variation in the cGMP-dependent protein kinase.

Left ventricular structure and function in relation to steroid biosynthesis genes in a white population.

Low-salt diet and diuretic effect on blood pressure and organ damage

MPO antibody-positive vasculitis in a patient with psoriatic arthritis and gold-induced membranous glomerulonephritis

Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin

MicroRNA 193b-3p as a predictive biomarker of chronic kidney disease in patients undergoing radical nephrectomy for renal cell carcinoma.

Na+, kidney, hypertension and genes

OASIS-HT: design of a pharmacogenomic dose-finding study

Ouabain Contributes to Kidney Damage in a Rat Model of Renal Ischemia-Reperfusion Injury