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Lista de obras de Themistocles L Assimes

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

artículo científico publicado en 2015

A genome-wide scan for circulating vascular adhesion protein-1 (VAP-1) levels: MACROD2 as a potential transcriptional regulator of adipogenesis

artículo científico publicado en 2018

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

artículo científico publicado en 2021

A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

artículo científico publicado en 2007

A systems biology framework identifies molecular underpinnings of coronary heart disease

artículo científico publicado en 2013

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

artículo científico publicado en 2011

Age at incident treatment of hypertension and risk of cancer: a population study

artículo científico

Age-related somatic structural changes in the nuclear genome of human blood cells

artículo científico publicado en 2012

An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies

artículo científico publicado en 2010

An epigenetic biomarker of aging for lifespan and healthspan

artículo científico publicado en 2018

An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease

artículo científico publicado en 2016

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

artículo científico publicado en 2019

Association Between Heart Failure and Postoperative Mortality Among Patients Undergoing Ambulatory Noncardiac Surgery

artículo científico publicado en 2019

Association analyses based on false discovery rate implicate new loci for coronary artery disease ⬇️

artículo científico

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels

artículo científico publicado en 2017

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

artículo científico publicado en 2011

Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis

artículo científico publicado en 2013

Association of APOL1 Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program

artículo científico publicado en 2019

Association of Left Ventricular Ejection Fraction and Symptoms With Mortality After Elective Noncardiac Surgery Among Patients With Heart Failure

scientific article published on 01 February 2019

Associations among multiple markers and complex disease: models, algorithms, and applications

artículo científico publicado en 2008

Associations between a Genetic Risk Score for Clinical CAD and Early Stage Lesions in the Coronary Artery and the Aorta

artículo científico publicado en 2016

Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry

artículo científico publicado en 2021

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease

scientific article published on 19 August 2019

Breastfeeding Duration and the Risk of Coronary Artery Disease ⬇️

scientific article published on 05 December 2018

Call to action: cardiovascular disease in Asian Americans: a science advisory from the American Heart Association

artículo científico publicado en 2010

Cardiac outcomes occurred more frequently with PCI than CABG or medical therapy in coronary artery disease.

artículo científico publicado en 2004

Cardioinformatics: the nexus of bioinformatics and precision cardiology

scientific article published on 04 December 2019

Central obesity is important but not essential component of the metabolic syndrome for predicting diabetes mellitus in a hypertensive family-based cohort. Results from the Stanford Asia-pacific program for hypertension and insulin resistance (SAPPHI

artículo científico publicado en 2012

Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci

artículo científico publicado en 2015

Characterizing the admixed African ancestry of African Americans

artículo científico publicado en 2009

Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction

artículo científico publicado en 2020

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

artículo científico publicado en 2021

Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community

artículo científico publicado en 2015

Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart disease

artículo científico publicado en 2007

Clinical interpretation and implications of whole-genome sequencing

artículo científico publicado en 2014

Clonal hematopoiesis associated with epigenetic aging and clinical outcomes

artículo científico publicado en 2021

Coffee consumption is associated with DNA methylation levels of human blood

artículo científico publicado en 2017

Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease

artículo científico publicado en 2008

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Comprehensive Investigation of Circulating Biomarkers and their Causal Role in Atherosclerosis-related Risk Factors and Clinical Events

artículo científico publicado en 2020

Contemporary Considerations for Constructing a Genetic Risk Score: An Empirical Approach.

artículo científico publicado en 2015

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation

artículo científico publicado en 2014

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

artículo científico publicado en 2015

Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

scientific article published on 19 April 2020

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

artículo científico publicado en 2017

DNA methylation GrimAge strongly predicts lifespan and healthspan

DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative

artículo científico publicado en 2015

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

artículo científico publicado en 2016

DNA methylation-based estimator of telomere length

artículo científico publicado en 2019

DNA methylation-based measures of biological age: meta-analysis predicting time to death

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

artículo científico publicado en 2010

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

artículo científico publicado en 2010

Detecting clinically meaningful biomarkers with repeated measurements: An illustration with electronic health records

artículo científico publicado en 2015

Digital ischemia

artículo científico publicado en 2008

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

artículo científico publicado en 2020

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study

scientific article published on 01 August 2018

Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus

artículo científico publicado en 2013

Dissecting the causal genetic mechanisms of coronary heart disease

artículo científico

Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses

artículo científico publicado en 2015

Effect of Common Genetic Variants of Growth Arrest-Specific 6 Gene on Insulin Resistance, Obesity and Type 2 Diabetes in an Asian Population

artículo científico publicado en 2015

Effects of Genetic Variants Associated with Familial Hypercholesterolemia on Low-Density Lipoprotein-Cholesterol Levels and Cardiovascular Outcomes in the Million Veteran Program

artículo científico publicado en 2018

Epigenetic Aging and Immune Senescence in Women With Insomnia Symptoms: Findings From the Women's Health Initiative Study

artículo científico publicado en 2016

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

artículo científico publicado en 2017

Epigenome-wide Association Study of Diet Quality in the Women's Health Initiative (OR31-06-19)

Epigenome-wide association study of diet quality in the Women's Health Initiative and TwinsUK cohort

artículo científico publicado en 2020

Erratum to: Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

artículo científico publicado en 2020

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort.

artículo científico publicado en 2018

Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study

artículo científico publicado en 2012

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

artículo científico publicado en 2014

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

artículo científico publicado en 2008

Family History of Heart Disease

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

artículo científico publicado en 2017

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci

artículo científico publicado en 2016

GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

artículo científico publicado en 2018

Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans

artículo científico publicado en 2016

Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

scientific article published on 28 September 2020

Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk ⬇️

artículo científico publicado el 11 de marzo de 2013

Genetic Risk Scores in Premature Coronary Artery Disease: Still Only One Piece of the Prevention Puzzle

artículo científico publicado en 2018

Genetic analysis for a shared biological basis between migraine and coronary artery disease

artículo científico publicado en 2015

Genetic cardiovascular risk prediction: are we already there?

Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes risk but not coronary artery disease

scientific article published on 24 August 2020

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

artículo científico publicado en 2012

Genetic evidence for causal relationships between age at natural menopause and the risk of ageing-associated adverse health outcomes

artículo científico publicado en 2022

Genetic evidence of assortative mating in humans

scholarly article

Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits

artículo científico publicado en 2022

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic susceptibility to peripheral arterial disease: a dark corner in vascular biology

artículo científico publicado en 2007

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

artículo científico publicado en 2013

Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk

artículo científico publicado en 2015

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association

artículo científico publicado en 2013

Genetics of 35 blood and urine biomarkers in the UK Biobank

Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium

artículo científico publicado en 2016

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

artículo científico publicado en 2018

Genetics: Implications for Prevention and Management of Coronary Artery Disease

artículo científico publicado en 2016

Genome-Wide Association Studies of Coronary Artery Disease: Recent Progress and Challenges Ahead

scientific article published on 18 July 2018

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

scientific article published on 01 November 2019

Genome-wide association study of peripheral artery disease in the Million Veteran Program

scientific article published on 08 July 2019

Genome-wide linkage analysis and regional fine mapping identified variants in the RYR3 gene as a novel quantitative trait locus for circulating adiponectin in Chinese population

artículo científico publicado en 2016

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genotyping Array Design and Data Quality Control in the Million Veteran Program

artículo científico publicado en 2020

Harmonizing Genetic Ancestry and Self-identified Race/Ethnicity in Genome-wide Association Studies

artículo científico publicado en 2019

HeartBioPortal

scientific article published on 16 April 2019

Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe Study

artículo científico publicado en 2007

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias ⬇️

artículo científico publicado el 21 de febrero de 2012

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Hypermetabolic macrophages in rheumatoid arthritis and coronary artery disease due to glycogen synthase kinase 3b inactivation.

artículo científico publicado en 2018

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

artículo científico publicado en 2016

Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion

artículo científico publicado en 2019

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

artículo científico publicado en 2011

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

artículo científico publicado en 2017

Immortal person time bias in pharmacoepidemiological studies of antihypertensive drugs

artículo científico publicado en 2011

Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study

artículo científico publicado en 2017

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

artículo científico publicado en 2013

Imputation of coding variants in African Americans: better performance using data from the exome sequencing project

artículo científico publicado en 2013

Inactivating mutations in NPC1L1 and protection from coronary heart disease

artículo científico publicado en 2014

Inhaled corticosteroid use in asthma and the prevention of myocardial infarction

artículo científico

Insulin resistance: regression and clustering

artículo científico publicado en 2014

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

artículo científico publicado en 2016

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

artículo científico publicado en 2014

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

artículo científico publicado en 2010

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

artículo científico publicado en 2011

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

Lean body mass and risk of incident atrial fibrillation in post-menopausal women

artículo científico publicado en 2015

Leukocyte Telomere Length and Risks of Incident Coronary Heart Disease and Mortality in a Racially Diverse Population of Postmenopausal Women

artículo científico publicado en 2015

Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study

artículo científico publicado en 2020

Leukocyte telomere length, T cell composition and DNA methylation age.

artículo científico publicado en 2017

Leveraging Multi-ethnic Evidence for Risk Assessment of Quantitative Traits in Minority Populations

artículo científico publicado en 2017

Leveraging Multi-ethnic Evidence for Risk Assessment of Quantitative Traits in Minority Populations

artículo científico publicado en 2017

Leveraging information from genetic risk scores of coronary atherosclerosis

artículo científico publicado en 2017

Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

artículo científico publicado en 2019

Leveraging population admixture to characterize the heritability of complex traits

artículo científico publicado en 2014

Long-term use of angiotensin receptor blockers and the risk of cancer ⬇️

artículo científico publicado en 2012

Long-term use of antihypertensive drugs and risk of cancer

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

artículo científico publicado en 2014

Low lifetime recreational activity is a risk factor for peripheral arterial disease

artículo científico publicado en 2011

Making the Most out of Mendel's Laws in Complex Coronary Artery Disease

artículo científico publicado en 2018

Measurement of insulin-mediated glucose uptake: direct comparison of the modified insulin suppression test and the euglycemic, hyperinsulinemic clamp

artículo científico publicado en 2012

Melanoma risk prediction using a multilocus genetic risk score in the Women's Health Initiative cohort.

artículo científico publicado en 2018

Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease

scientific article published on 27 August 2020

Menopause accelerates biological aging

artículo científico publicado en 2016

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

artículo científico publicado en 2014

Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation

scientific article published on 14 June 2019

Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study

artículo científico publicado en 2020

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

artículo científico publicado en 2014

Near-term prediction of sudden cardiac death in older hemodialysis patients using electronic health records

scientific article published on 31 October 2013

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Obesity, physical activity, and their interaction in incident atrial fibrillation in postmenopausal women

artículo científico publicado en 2014

PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort

artículo científico publicado en 2020

Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease

article

Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset

artículo científico publicado en 2013

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

artículo científico publicado en 2011

Randomized trial of personal genomics for preventive cardiology: design and challenges

artículo científico publicado en 2012

Sex differences in the prevalence of peripheral artery disease in patients undergoing coronary catheterization

artículo científico

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants

artículo científico publicado en 2014

Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

artículo científico publicado en 2014

Study of exonic variation identifies incremental information regarding lipid-related and coronary heart disease genes

artículo científico publicado en 2014

Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course

artículo científico publicado en 2015

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

scientific article published on 28 April 2008

Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

artículo científico publicado en 2015

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Project Baseline Health Study: a step towards a broader mission to map human health

scientific article published on 05 June 2020

The associations of leptin, adiponectin and resistin with incident atrial fibrillation in women

artículo científico publicado en 2016

The combination of 9p21.3 genotype and biomarker profile improves a peripheral artery disease risk prediction model

artículo científico publicado en 2013

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

artículo científico publicado en 2016

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

artículo científico publicado en 2016

The power of genetic diversity in genome-wide association studies of lipids

The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study

artículo científico publicado en 2020

The relationship of lipoprotein(a), C-reactive protein and homocysteine with metabolic syndrome in South Asians

article

The role of epigenetic aging in education and racial/ethnic mortality disparities among older U.S. Women

artículo científico publicado en 2019

The shared allelic architecture of adiponectin levels and coronary artery disease ⬇️

artículo científico publicado el 22 de abril de 2013

The use of perioperative corticosteroids in craniomaxillofacial surgery

artículo científico

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population

artículo científico publicado en 2013

Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci

artículo científico publicado en 2017

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

artículo científico publicado en 2013

Transcriptomic signatures across human tissues identify functional rare genetic variation

artículo científico publicado en 2020

Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank: Observational and Mendelian Randomization Analyses

scientific article published on 03 February 2020

Use of Medicare data to identify coronary heart disease outcomes in the Women's Health Initiative.

artículo científico publicado en 2014

Use of venlafaxine compared with other antidepressants and the risk of sudden cardiac death or near death: a nested case-control study

artículo científico publicado en 2010

Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program

artículo científico publicado en 2020

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

artículo científico publicado en 2014

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