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Lista de obras de Fredrik Karpe

A "futile cycle" induced by thiazolidinediones in human adipose tissue?

artículo científico publicado en 2003

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels

article

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

artículo científico publicado en 2007

A common variant in the FTO locus is associated with waist-hip ratio in Indian adolescents

artículo científico publicado en 2013

A decrease in cardiovascular risk factors in healthy 40-year-old Swedish men between 1980-1983 and 1991-1992.

artículo científico publicado en 1996

A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia

artículo científico publicado en 2000

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice

artículo científico publicado en 2008

ADRB2 Arg16Gly polymorphism in the LARGE trial

artículo científico publicado en 2010

Absence of birth-weight lowering effect of ADCY5 and near CCNL, but association of impaired glucose-insulin homeostasis with ADCY5 in Asian Indians

artículo científico publicado en 2011

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway

artículo científico publicado en 1996

Activation of coagulation factor VII during alimentary lipemia.

artículo científico publicado en 1994

Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.

artículo científico publicado en 2007

Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes.

artículo científico

Adipose tissue fatty acid metabolism and cardiovascular disease

artículo científico publicado en 2005

Adipose tissue fatty acid metabolism in insulin-resistant men

scholarly article by A. S. T. Bickerton et al published 1 August 2008 in Diabetologia

Adipose tissue fatty acid metabolism in insulin-resistant men.

artículo científico publicado en 2008

Adipose tissue function in the insulin-resistance syndrome

artículo científico publicado en 2005

Adipose tissue: a key target for diabetes pathophysiology and treatment?

artículo científico publicado en 2007

Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation

article published in 1998

Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men.

artículo científico publicado en 1999

Alterations of VLDL composition during alimentary lipemia

artículo científico publicado en 1997

An atlas of G-protein coupled receptor expression and function in human subcutaneous adipose tissue

artículo científico

Analysis of the frequency and spectrum of mutations recognised to cause familial hypercholesterolaemia in routine clinical practice in a UK specialist hospital lipid clinic

artículo científico publicado en 2013

Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans.

artículo científico publicado en 2006

Apolipoprotein B-48

scientific article published on 01 January 1996

Apolipoprotein M can discriminate HNF1A-MODY from Type 1 diabetes

artículo científico publicado en 2013

Assessing association between protein truncating variants and quantitative traits

artículo científico publicado en 2013

Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations

artículo científico publicado en 2010

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association of adipose tissue blood flow with fat depot sizes and adipokines in women

artículo científico publicado en 2011

Association of insulin and insulin propeptides with an atherogenic lipoprotein phenotype

artículo científico publicado en 1995

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome

artículo científico publicado en 2008

Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts.

artículo científico publicado en 2019

Associations of Variants inFTOand NearMC4RWith Obesity Traits in South Asian Indians

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

article

Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes.

artículo científico publicado en 2014

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers

artículo científico publicado en 2014

Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy.

artículo científico publicado en 2005

Chylomicron production as a feature of atherogenic lipoproteins

artículo científico publicado el 1 de agosto de 2012

Chylomicron-Derived Fatty Acid Spillover in Adipose Tissue: A Signature of Metabolic Health?

artículo científico publicado en 2017

Chylomicron/chylomicron remnant turnover in humans: evidence for margination of chylomicrons and poor conversion of larger to smaller chylomicron remnants

artículo científico publicado en 1997

Circulating MicroRNAs: What Is Their Relevance?

Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man.

artículo científico publicado en 2009

Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans

artículo científico publicado el 1 de noviembre de 1997

Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes

artículo científico publicado en 2012

Cohort Profile: The Oxford Biobank

artículo científico publicado en 2017

Common variants near MC4R are associated with fat mass, weight and risk of obesity

artículo científico publicado en 2008

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

artículo científico publicado en 2008

Common variation in the gene for apolipoprotein B modulates postprandial lipoprotein metabolism: a hypothesis generating study

artículo científico publicado en 1995

Comparative protein profiling of serum and plasma using an antibody suspension bead array approach

artículo científico publicado en 2010

Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk

artículo científico publicado en 2017

Composition of human low density lipoprotein: effects of postprandial triglyceride-rich lipoproteins, lipoprotein lipase, hepatic lipase and cholesteryl ester transfer protein

artículo científico publicado en 1993

Comprehensive human adipose tissue mRNA and microRNA endogenous control selection for quantitative real-time-PCR normalization

artículo científico publicado en 2010

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans

artículo científico publicado en 2009

Coupling of metabolism and cardiovascular responses

article

DNA methylation of genes in adipose tissue.

artículo científico publicado en 2010

Determinants of VLDL-triglycerides production

artículo científico publicado en 2012

Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE

scientific article published on 01 July 1994

Development of an arterio-venous difference method to study the metabolic physiology of the femoral adipose tissue depot

artículo científico publicado en 2010

Dietary fat and insulin sensitivity

artículo científico publicado en 2010

Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state

artículo científico publicado en 2006

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma

artículo científico publicado el 1 de julio de 1998

Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate.

artículo científico publicado en 2008

Differences in postprandial concentrations of very-low-density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease

artículo científico publicado en 1999

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications

artículo científico publicado en 2014

Distribution of PCB congeners, DDE, hexachlorobenzene, and methylsulfonyl metabolites of PCB and DDE among various fractions of human blood plasma

artículo científico publicado en 1999

Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?

artículo científico publicado en 2010

Dyslipoproteinemic changes in borderline hypertension

artículo científico publicado en 1994

Dysregulation of subcutaneous adipose tissue blood flow in overweight postmenopausal women

artículo científico publicado en 2010

Effects of Peroxisome Proliferator-Activated Receptor-α and -γ Agonists on 11β-Hydroxysteroid Dehydrogenase Type 1 in Subcutaneous Adipose Tissue in Men

artículo científico publicado en 2007

Effects of Recombinant Apolipoprotein A-I Milano on Aortic Atherosclerosis in Apolipoprotein E–Deficient Mice

artículo científico publicado el 3 de marzo de 1998

Effects of a cardioselective beta-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk

artículo científico publicado en 1998

Effects of acute administration of doxazosin on fasting and postprandial haemodynamics and lipid metabolism in healthy subjects

artículo científico publicado en 2002

Effects of atorvastatin on postprandial plasma lipoproteins in postinfarction patients with combined hyperlipidaemia

artículo científico publicado en 2002

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach

artículo científico publicado en 2012

Effects of insulin on adipose tissue blood flow in man.

artículo científico publicado en 2002

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells

Elevated levels of factor VII activity in the postprandial state: effect of the factor VII Arg-Gln polymorphism

artículo científico publicado en 1994

Endogenous triglyceride-rich lipoproteins accumulate in rat plasma when competing with a chylomicron-like triglyceride emulsion for a common lipolytic pathway.

artículo científico publicado en 1995

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2018

European Lipoprotein Club: Report of the 27th ELC Annual Conference, Tutzing, 6–9 September 2004

European Lipoprotein Club: Report of the 28th ELC Annual Conference, Tutzing, 12–15 September 2005

European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006.

artículo científico publicado en 2007

European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007.

artículo científico publicado en 2008

European Lipoprotein Club: report of the 26th ELC Annual Conference, Tutzing, 8-11 September 2003.

artículo científico publicado en 2004

Exercise prevents the accumulation of triglyceride-rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet

artículo científico publicado en 2001

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

FTO genetic variants and risk of obesity and type 2 diabetes: a meta-analysis of 28,394 Indians

artículo científico publicado en 2013

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

artículo científico publicado en 2015

Failure to increase postprandial blood flow in subcutaneous adipose tissue is associated with tissue resistance to adrenergic stimulation

artículo científico publicado en 2011

Familial hypercholesterolaemia

artículo científico publicado en 2012

Fasted to fed trafficking of Fatty acids in human adipose tissue reveals a novel regulatory step for enhanced fat storage

artículo científico publicado en 2009

Fatty acid metabolism in patients with PPARgamma mutations

artículo científico publicado en 2008

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation

artículo científico publicado en 2014

Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased.

artículo científico publicado en 2007

Fatty acids, obesity, and insulin resistance: time for a reevaluation

artículo científico publicado en 2011

Femoral adipose tissue may accumulate the fat that has been recycled as VLDL and nonesterified fatty acids

artículo científico publicado en 2010

Functional characterization of 4 polymorphisms in promoter region of hepatic lipase gene

artículo científico publicado en 2000

Genetic evidence of assortative mating in humans

scholarly article

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomics of Adipose Tissue

Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome

artículo científico publicado en 2008

Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome

artículo científico publicado en 2007

Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans

artículo científico publicado en 2012

Gluteofemoral body fat as a determinant of metabolic health.

artículo científico publicado en 2010

Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?

artículo científico publicado en 2010

HDLs and alimentary lipemia. Studies in men with previous myocardial infarction at a young age.

artículo científico publicado en 1993

Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism

scientific article published on 01 March 2020

High-density lipoprotein: Relations to metabolic parameters and severity of coronary artery disease

artículo científico publicado en 1996

Human adipose tissue blood flow and micromanipulation of human subcutaneous blood flow

artículo científico publicado en 2008

Human intestinal alkaline phosphatase--release to the blood is linked to lipid absorption, but removal from the blood is not linked to lipoprotein clearance

artículo científico publicado en 1993

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma

artículo científico publicado en 2003

Hyperlipidaemia and cardiovascular disease: nonantilipolytic effects of nicotinic acid in adipose tissue

artículo científico publicado en 2010

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

artículo científico publicado en 2015

Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity

artículo científico publicado en 2002

In vitro and in vivo lipolysis of plasma triglycerides increases the resistance to oxidative modification of low-density lipoproteins

artículo científico publicado en 2003

In vivo demonstration in humans that large postprandial triglyceride-rich lipoproteins activate coagulation factor VII through the intrinsic coagulation pathway

artículo científico publicado en 1996

Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis

artículo científico publicado en 2011

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.

artículo científico publicado en 2003

Influence of dietary fats on pancreatic phospholipids of chronically ethanol-treated rats

scientific article published on 01 September 1988

Insulin and non-esterified fatty acid relations to alimentary lipaemia and plasma concentrations of postprandial triglyceride-rich lipoproteins in healthy middle-aged men.

artículo científico publicado en 2000

Insulin resistance by adiponectin deficiency: is the action in skeletal muscle?

artículo científico publicado en 2013

Insulin sensitisation affects lipoprotein lipase transport in type 2 diabetes: role of adipose tissue and skeletal muscle in response to rosiglitazone

article

Integrative physiology of human adipose tissue

scientific article published on 01 August 2003

Interaction between specific fatty acids, GLP-1 and insulin secretion in humans

artículo científico publicado en 2002

Interactions amongst insulin, lipoproteins and haemostatic function relevant to coronary heart disease.

artículo científico publicado en 1994

Is there something special about palmitoleate?

artículo científico publicado en 2013

LDL particle size distribution is associated with carotid intima-media thickness in healthy 50-year-old men.

artículo científico publicado en 1999

LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion.

artículo científico publicado en 2015

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

artículo científico publicado en 2023

Lipoprotein lipase in plasma after an oral fat load: relation to free fatty acids

artículo científico publicado el 1 de julio de 1992

Lipoprotein lipase mass and activity in plasma and their increase after heparin are separate parameters with different relations to plasma lipoproteins

artículo científico publicado en 1995

Lipoprotein lipase transport in plasma: role of muscle and adipose tissues in regulation of plasma lipoprotein lipase concentrations.

artículo científico publicado en 1998

Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein

artículo científico publicado en 1988

Low frequency and rare coding variation contributes to multiple sclerosis risk

Lower resting and total energy expenditure in postmenopausal compared with premenopausal women matched for abdominal obesity

artículo científico publicado en 2014

Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men.

artículo científico publicado en 1998

Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo

artículo científico publicado en 2012

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Metabolic signatures of human adipose tissue hypoxia in obesity

artículo científico publicado en 2012

Metabolism of triglyceride-rich lipoproteins during alimentary lipemia

artículo científico publicado en 1993

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven

artículo científico publicado en 2011

MicroRNAs in adipose tissue: their role in adipogenesis and obesity

artículo científico publicado en 2012

Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles

artículo científico publicado en 2005

Monitoring adipose tissue blood flow in man: a comparison between the 133xenon washout method and microdialysis

artículo científico publicado el 1 de enero de 2002

More than meets the eye: the ACCORD trial and use of statin-fibrate combination in type 2 diabetes mellitus

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

artículo científico publicado en 2016

Nitric oxide and beta-adrenergic stimulation are major regulators of preprandial and postprandial subcutaneous adipose tissue blood flow in humans

artículo científico publicado en 2003

Novel experimental protocol to increase specific plasma nonesterified fatty acids in humans

artículo científico publicado en 2002

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Obesity--On or Off?

artículo científico publicado en 2016

Oscillations of fatty acid and glycerol release from human subcutaneous adipose tissue in vivo

artículo científico publicado en 2005

PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function

artículo científico publicado en 2009

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

PTEN mutations as a cause of constitutive insulin sensitivity and obesity.

artículo científico publicado en 2012

Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding

artículo científico publicado en 2008

Perioperative insulin and glucose infusion maintains normal insulin sensitivity after surgery.

artículo científico publicado en 1998

Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men.

artículo científico publicado en 2003

Physical activity and exercise in the regulation of human adipose tissue physiology

artículo científico

Plasma leptin is influenced by diet composition and exercise

article

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men.

artículo científico publicado en 2002

Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis

artículo científico publicado en 2002

Postprandial lipemia--effect of lipid-lowering drugs

artículo científico publicado en 2002

Postprandial lipoprotein metabolism and atherosclerosis

scientific article published on 01 June 1995

Postprandial lipoprotein metabolism and atherosclerosis.

artículo científico publicado en 1999

Postprandial lipoproteins and progression of coronary atherosclerosis

artículo científico publicado en 1994

Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene

artículo científico publicado en 2002

Preferential uptake of dietary Fatty acids in adipose tissue and muscle in the postprandial period

artículo científico publicado en 2007

Prevalence, incidence and predictors of cardiovascular risk factors: longitudinal data from rural and urban South India and comparison with global data

scientific article published on 01 October 2020

Proneness to formation of tight and rigid fibrin gel structures in men with myocardial infarction at a young age

scientific article published on 01 October 1996

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Proteomic analysis of human adipose tissue after rosiglitazone treatment shows coordinated changes to promote glucose uptake

artículo científico publicado en 2009

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry.

artículo científico publicado en 2011

Quantification of postprandial triglyceride-rich lipoproteins in healthy men by retinyl ester labeling and simultaneous measurement of apolipoproteins B-48 and B-100.

artículo científico publicado en 1995

RANTES release by human adipose tissue in vivo and evidence for depot-specific differences

artículo científico publicado en 2009

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo

artículo científico publicado en 2012

Reduced oxidation of dietary fat after a short term high-carbohydrate diet

artículo científico publicado en 2008

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

artículo científico publicado en 2018

Regional fat depot masses are influenced by protein-coding gene variants

article

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

artículo científico publicado en 2013

Regulation of human metabolism by hypoxia-inducible factor

artículo científico publicado en 2010

Regulation of human subcutaneous adipose tissue blood flow

artículo científico

Regulation of subcutaneous adipose tissue blood flow is related to measures of vascular and autonomic function

artículo científico publicado en 2010

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

artículo científico publicado en 2018

Relationship of tissue factor pathway inhibitor activity to plasma lipoproteins and myocardial infarction at a young age.

artículo científico publicado en 1994

Relationships of low density lipoprotein subfractions to angiographically defined coronary artery disease in young survivors of myocardial infarction

artículo científico publicado en 1991

Relationships of thrombosis and fibrinolysis to atherosclerosis.

artículo científico publicado en 1994

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides

artículo científico publicado en 2001

Remnant-like lipoprotein particle cholesterol concentration and progression of coronary and vein-graft atherosclerosis in response to gemfibrozil treatment

artículo científico publicado en 2001

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

artículo científico publicado en 2008

Removal of triacylglycerols from chylomicrons and VLDL by capillary beds: the basis of lipoprotein remnant formation.

artículo científico publicado en 2007

Republished review: Triglycerides and atherogenic dyslipidaemia: extending treatment beyond statins in the high-risk cardiovascular patient

artículo científico publicado el 1 de noviembre de 2011

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

artículo científico publicado en 2016

Response to Janiszewski et al

Risk of Fatal Stroke in Patients With Treated Familial Hypercholesterolemia

artículo científico publicado en 2003

Role of developmental transcription factors in white, brown and beige adipose tissues.

artículo científico publicado en 2015

Rosiglitazone decreases postprandial production of acylation stimulating protein in type 2 diabetics

artículo científico publicado en 2007

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma

artículo científico publicado en 2005

Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period.

artículo científico publicado en 2003

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

artículo científico publicado en 2017

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Short-term hypocaloric nutrition but not bed rest decrease insulin sensitivity and IGF-I bioavailability in healthy subjects: the importance of glucagon

artículo científico publicado en 1997

Structural and functional properties of deep abdominal subcutaneous adipose tissue explain its association with insulin resistance and cardiovascular risk in men.

artículo científico publicado en 2013

Studies on the lecithin: cholesterol acyltransferase substrate properties of HDL as determined by its subclass distribution analysed by gradient gel electrophoresis

artículo científico publicado en 1990

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides

artículo científico publicado en 2018

Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling.

artículo científico publicado en 2009

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The antidiabetogenic effect of GLP-1 is maintained during a 7-day treatment period and improves diabetic dyslipoproteinemia in NIDDM patients

artículo científico publicado en 1996

The contribution of splanchnic fat to VLDL triglyceride is greater in insulin-resistant than insulin-sensitive men and women: studies in the postprandial state

artículo científico publicado en 2007

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease

artículo científico publicado en 2011

The effects of APOE on the functional architecture of the resting brain

artículo científico publicado en 2011

The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes

artículo científico publicado en 2004

The genetic architecture of type 2 diabetes

artículo científico publicado en 2016

The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank

artículo científico publicado en 2005

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease

artículo científico publicado en 2004

The minor allele of the missense polymorphism Ser251Pro in perilipin 2 (PLIN2) disrupts an α-helix, affects lipolysis, and is associated with reduced plasma triglyceride concentration in humans

artículo científico publicado en 2013

The nicotinic acid receptor--a new mechanism for an old drug

artículo científico publicado en 2004

The power of genetic diversity in genome-wide association studies of lipids

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

artículo científico publicado en 2013

Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia

artículo científico publicado en 2007

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Transcriptional control of human adipose tissue blood flow

artículo científico publicado en 2009

Transient triglyceridemia decreases vascular reactivity in young, healthy men without risk factors for coronary heart disease

artículo científico publicado en 1997

Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro

artículo científico publicado el 1 de febrero de 1998

Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Tr

artículo científico publicado en 1998

Triglycerides and atherogenic dyslipidaemia: extending treatment beyond statins in the high-risk cardiovascular patient

artículo científico publicado el 1 de marzo de 2011

Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans

artículo científico publicado en 2004

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

artículo científico publicado en 2013

Using a new socioepidemiological questionnaire to analyse associations between intergenerational upward social mobility and body fat distribution: a pilot study with the Oxford BioBank cohort

artículo científico publicado en 2020

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index

artículo científico publicado en 2002

Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis

scientific article published on 19 November 2007

Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia

article

Weight Gain and Height Growth during Infancy, Childhood, and Adolescence as Predictors of Adult Cardiovascular Risk

artículo científico publicado en 2016

Whole exome sequencing of familial hypercholesterolaemia patients negative for LDLR/APOB/PCSK9 mutations

artículo científico publicado en 2014

Why, when and how should hypertriglyceridemia be treated in the high-risk cardiovascular patient?

artículo científico publicado el 1 de agosto de 2011

Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

artículo científico publicado en 2011

[Can cholesterol lowering treatment have unwanted effects?]

artículo científico publicado en 1991

[Low cholesterol level--symptom of a disease?]

scientific article published on 01 December 1988