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Lista de obras de Sharon Lewin

A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?

artículo científico publicado en 2016

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals

artículo científico publicado en 2017

A cautionary tale: fatal lactic acidosis complicating nucleoside analogue and metformin therapy

artículo científico publicado en 2003

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

artículo científico publicado en 2013

A cure for HIV: where we've been, and where we're headed

artículo científico publicado en 2013

A new way of measuring apoptosis by absolute quantitation of inter-nucleosomally fragmented genomic DNA.

artículo científico publicado en 2012

A novel, rapid method to detect infectious HIV-1 from plasma of persons infected with HIV-1.

artículo científico publicado en 2010

A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibodies, (PE)HRG214, in HIV-1-infected individuals

artículo científico publicado en 2004

A randomized trial of combination hepatitis B therapy in HIV/HBV coinfected antiretroviral naïve individuals in Thailand

artículo científico publicado en 2008

A systematic review of T-cell epitopes in hepatitis B virus: identification, genotypic variation and relevance to antiviral therapeutics.

artículo científico publicado en 2008

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

artículo científico publicado en 2014

Age-dependent changes in T cell homeostasis and SIV load in sooty mangabeys

artículo científico publicado en 2000

Altering cell death pathways as an approach to cure HIV infection

artículo científico publicado en 2013

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

artículo científico publicado en 2013

Analysis of clinical HIV-1 strains with resistance to maraviroc reveals strain-specific resistance mutations, variable degrees of resistance, and minimal cross-resistance to other CCR5 antagonists.

artículo científico publicado en 2017

Analysis of hepatitis B viral load decline under potent therapy: complex decay profiles observed.

artículo científico publicado en 2001

Antenatal screening practice for infectious diseases by general practitioners in Australia

artículo científico publicado en 2009

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy

artículo científico publicado en 2016

Antibody and B-cell responses may control circulating lipopolysaccharide in patients with HIV infection

artículo científico publicado en 2011

Assessment of HBV flare in a randomized clinical trial in HIV/HBV coinfected subjects initiating HBV-active antiretroviral therapy in Thailand

artículo científico publicado en 2012

Associations between surface markers on blood monocytes and carotid atherosclerosis in HIV-positive individuals.

artículo científico publicado en 2013

Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy

artículo científico publicado en 2010

Barriers and strategies to achieve a cure for HIV

article

Biological determinants of immune reconstitution in HIV-infected patients receiving antiretroviral therapy: the role of interleukin 7 and interleukin 7 receptor α and microbial translocation.

artículo científico publicado en 2010

Biomarkers of immune dysfunction following combination antiretroviral therapy for HIV infection

artículo científico publicado en 2011

Biomarkers of inflammation and coagulation are associated with mortality and hepatitis flares in persons coinfected with HIV and hepatitis viruses

artículo científico publicado en 2013

Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy

artículo científico publicado en 2010

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

artículo científico publicado en 2020

Broad activation of latent HIV-1 in vivo

artículo científico publicado en 2016

CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency

artículo científico publicado en 2007

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.

artículo científico publicado en 2016

CD4+ T cell signatures in HIV infection

scientific article published on 01 August 2019

CD4+ T-Cell Deficiency in HIV Patients Responding to Antiretroviral Therapy Is Associated With Increased Expression of Interferon-Stimulated Genes in CD4+ T Cells

artículo científico publicado en 2011

CNS-specific regulatory elements in brain-derived HIV-1 strains affect responses to latency-reversing agents with implications for cure strategies

artículo científico publicado en 2015

CXCL-10, interleukin-12 and interleukin-21 are not immunological predictors of HBeAg seroconversion in HIV-1-HBV coinfection following HBV-active antiretroviral therapy

artículo científico publicado en 2014

CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles

artículo científico publicado en 2016

Cancer therapies in HIV cure research

artículo científico publicado en 2016

Changes in mitochondrial DNA in peripheral blood mononuclear cells from HIV-infected patients with lipoatrophy randomized to receive abacavir

artículo científico publicado en 2004

Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy

artículo científico publicado en 2006

Chemokine levels and chemokine receptor expression in the blood and the cerebrospinal fluid of HIV-infected patients with cryptococcal meningitis and cryptococcosis-associated immune reconstitution inflammatory syndrome

artículo científico publicado en 2013

Chronic hepatitis B infection and pregnancy

artículo científico

Circulating heat shock protein 60 levels are elevated in HIV patients and are reduced by anti-retroviral therapy

artículo científico publicado en 2012

Clinical and mycological predictors of cryptococcosis-associated immune reconstitution inflammatory syndrome

artículo científico publicado en 2013

Clinical and virological predictors of hepatic flares in pregnant women with chronic hepatitis B.

artículo científico publicado en 2014

Clinical predictors of immune reconstitution following combination antiretroviral therapy in patients from the Australian HIV Observational Database

artículo científico publicado en 2011

Coinfection of hepatic cell lines with human immunodeficiency virus and hepatitis B virus leads to an increase in intracellular hepatitis B surface antigen

artículo científico publicado en 2010

Combination HBV therapy is linked to greater HBV DNA suppression in a cohort of lamivudine-experienced HIV/HBV coinfected individuals

artículo científico publicado en 2009

Combination Immune Checkpoint Blockade to Reverse HIV Latency

scientific article published on 27 January 2020

Comparison of Etests and Vitek 2 ® to broth microdilution for the susceptibility testing of Cryptococcus neoformans

artículo científico publicado en 2014

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

artículo científico publicado en 2013

Comparison of real-time PCR assays for monitoring serum hepatitis B virus DNA levels during antiviral therapy

artículo científico publicado en 2006

Comparison of sequence analysis and a novel discriminatory real-time PCR assay for detection and quantification of Lamivudine-resistant hepatitis B virus strains.

artículo científico publicado en 2004

Compartmentalization of innate immune responses in the central nervous system during cryptococcal meningitis/HIV coinfection

artículo científico publicado en 2014

Correction: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission

artículo científico publicado en 2016

Cryptococcosis-IRIS is associated with lower cryptococcus-specific IFN-γ responses before antiretroviral therapy but not higher T-cell responses during therapy

artículo científico publicado en 2013

Cytomegalovirus Reactivation Is Associated with Increased Risk of Late-Onset Invasive Fungal Disease after Allogeneic Hematopoietic Stem Cell Transplantation: A Multicenter Study in the Current Era of Viral Load Monitoring

artículo científico publicado en 2017

Decline in serum 25 hydroxyvitamin D levels in HIV-HBV-coinfected patients after long-term antiretroviral therapy

artículo científico publicado en 2013

Decreased NK Cell FcRgamma in HIV-1 infected individuals receiving combination antiretroviral therapy: a cross sectional study

artículo científico publicado en 2010

Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance

artículo científico publicado en 2008

Developing research priorities for Australia's response to infectious disease emergencies

article

Differential dynamics of donor DC and non-DC peripheral blood mononuclear cell microchimerism in lung transplantation.

artículo científico publicado en 2009

Differential expression of CD163 on monocyte subsets in healthy and HIV-1 infected individuals.

artículo científico publicado en 2011

Disseminated histoplasmosis: successful maintenance therapy with oral fluconazole

scientific article published on 01 February 1995

Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

artículo científico publicado en 1999

Early events of HIV-1 infection: can signaling be the next therapeutic target?

artículo científico publicado en 2011

Early experience with antimicrobial stewardship ward rounds at a tertiary referral hospital

artículo científico publicado en 2012

Ebola and HIV: managing febrile times

artículo científico publicado en 2014

Editorial: HIV and lipopolysaccharide: double trouble in the liver

article

Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma

artículo científico publicado en 2015

Effects of HIV-1 infection in vitro on transendothelial migration by monocytes and monocyte-derived macrophages.

artículo científico publicado en 2009

Effects of long-term tenofovir-based combination antiretroviral therapy in HIV-hepatitis B virus coinfection on persistent hepatitis B virus viremia and the role of hepatitis B virus quasispecies diversity.

artículo científico publicado en 2016

Efficacy of tenofovir disoproxil fumarate/emtricitabine compared with emtricitabine alone in antiretroviral-naive HIV-HBV coinfection in Thailand

artículo científico publicado en 2010

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.

artículo científico publicado en 2017

Enhanced replicative capacity and pathogenicity of HIV-1 isolated from individuals infected with drug-resistant virus and declining CD4+ T-cell counts

artículo científico publicado en 2005

Enrichment of gut-derived Fusobacterium is associated with suboptimal immune recovery in HIV-infected individuals

artículo científico publicado en 2018

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.

artículo científico publicado en 2013

Entry of HIV in primary human resting CD4(+) T cells pretreated with the chemokine CCL19.

artículo científico publicado en 2014

Erratum to: HIV integration sites in latently infected cell lines: evidence of ongoing replication

artículo científico publicado en 2017

Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.

artículo científico publicado en 2010

Ethics and hepatitis B cure research.

artículo científico publicado en 2016

Ethics of ART interruption after stem-cell transplantation

artículo científico publicado en 2016

Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy.

artículo científico publicado en 2014

Experiences and expectations of participants completing an HIV cure focused clinical trial

artículo científico publicado en 2015

Exposure to dideoxynucleosides is reflected in lowered mitochondrial DNA in subcutaneous fat.

artículo científico publicado en 2002

Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells

artículo científico publicado en 2011

Extremely prolonged HIV seroconversion associated with an MHC haplotype carrying disease susceptibility genes for antibody deficiency disorders

article

Factors associated with elevated ALT in an international HIV/HBV co-infected cohort on long-term HAART

artículo científico publicado en 2011

Fatal acute varicella-zoster virus hemorrhagic meningomyelitis with necrotizing vasculitis in an HIV-infected patient

artículo científico publicado en 2009

Finding a cure for HIV: much work to do.

artículo científico publicado en 2014

Finding a cure for HIV: will it ever be achievable?

artículo científico publicado en 2011

Future directions in the treatment of HIV-HBV coinfection

artículo científico publicado en 2009

Gender Differences in Emerging Infectious Diseases

Genetic polymorphisms in the CD14 gene are associated with monocyte activation and carotid intima-media thickness in HIV-infected patients on antiretroviral therapy

artículo científico publicado en 2016

Getting the "Kill" into "Shock and Kill": Strategies to Eliminate Latent HIV.

artículo científico publicado en 2018

Graves' disease during immune reconstitution after highly active antiretroviral therapy for HIV infection: evidence of thymic dysfunction

artículo científico publicado en 2004

HBV mutations in untreated HIV-HBV co-infection using genomic length sequencing

artículo científico publicado en 2010

HDAC inhibitors in HIV.

artículo científico publicado en 2011

HIV Infection and TLR Signalling in the Liver

artículo científico publicado en 2012

HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days--Implications for HIV Remission

artículo científico publicado en 2015

HIV Reservoirs and Strategies for Eradication

artículo científico publicado el 1 de marzo de 2012

HIV and aging: an overview of an emerging issue

artículo científico publicado en 2011

HIV and co-infections

artículo científico publicado en 2013

HIV cure and eradication: how will we get from the laboratory to effective clinical trials?

artículo científico publicado en 2011

HIV cure research: print and online media reporting in Australia

artículo científico publicado en 2017

HIV infection: epidemiology, pathogenesis, treatment, and prevention

artículo científico publicado en 2014

HIV inhibits early signal transduction events triggered by CD16 cross-linking on NK cells, which are important for antibody-dependent cellular cytotoxicity

artículo científico publicado en 2010

HIV integration and the establishment of latency in CCL19-treated resting CD4(+) T cells require activation of NF-κB.

artículo científico publicado en 2016

HIV integration sites and implications for maintenance of the reservoir

artículo científico publicado en 2017

HIV integration sites in latently infected cell lines: evidence of ongoing replication.

artículo científico publicado en 2017

HIV latency reversing agents act through Tat post translational modifications.

artículo científico publicado en 2018

HIV persistence: chemokines and their signalling pathways.

artículo científico publicado en 2012

HIV replication is associated with increased severity of liver biopsy changes in HIV-HBV and HIV-HCV co-infection.

artículo científico publicado en 2012

HIV research in Australia: linking basic research findings with clinical and public health outcomes

artículo científico publicado en 2006

HIV-1 DNA and mRNA concentrations are similar in peripheral blood monocytes and alveolar macrophages in HIV-1-infected individuals

article

HIV-1 cell entry and advances in viral entry inhibitor therapy

artículo científico publicado en 2003

HIV-1 down-modulates gamma signaling chain of Fc gamma R in human macrophages: a possible mechanism for inhibition of phagocytosis

artículo científico publicado en 2002

HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategies

artículo científico publicado en 2014

HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism

artículo científico publicado en 2011

HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry

artículo científico publicado en 2011

HIV-hepatitis B virus co-infection: epidemiology, pathogenesis, and treatment.

artículo científico publicado en 2017

HealthMap: a cluster randomised trial of interactive health plans and self-management support to prevent coronary heart disease in people with HIV.

artículo científico publicado en 2016

Hepatitis B and Delta virus are prevalent but often subclinical co-infections among HIV infected patients in Guinea-Bissau, West Africa: a cross-sectional study

artículo científico publicado en 2014

Hepatitis B treatment: rational combination chemotherapy based on viral kinetic and animal model studies.

artículo científico publicado en 2002

Hepatitis C Virus (HCV) Clearance After Treatment With Direct-Acting Antivirals in Human Immunodeficiency Virus (HIV)-HCV Coinfection Modulates Systemic Immune Activation and HIV Transcription on Antiretroviral Therapy

scientific article published on 02 April 2020

Hepatitis C prevalence among HIV-infected patients in Guinea-Bissau: a descriptive cross-sectional study

artículo científico publicado en 2014

Hepatitis virus immune restoration disease of the liver

artículo científico publicado en 2008

Highly reproducible transient transfections for the study of hepatitis B virus replication based on an internal GFP reporter system

artículo científico publicado en 2004

Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy

artículo científico publicado en 2017

Human cytomegalovirus (CMV)-specific CD8+ T cell responses are reduced in HIV-infected individuals with a history of CMV disease despite CD4+ T cell recovery

artículo científico publicado en 2007

Human immunodeficiency virus infection and the liver

artículo científico publicado en 2012

Human thymic dendritic cells: regulators of T cell development in health and HIV-1 infection

artículo científico publicado en 2007

Identification of a novel hepatitis B virus precore/core deletion mutant in HIV/hepatitis B virus co-infected individuals

artículo científico publicado en 2007

Identification of lineage relationships and novel markers of blood and skin human dendritic cells

artículo científico publicado en 2012

Identifying Cytomegalovirus Complications Using the Quantiferon-CMV Assay After Allogeneic Hematopoietic Stem Cell Transplantation

artículo científico publicado en 2017

Identifying Key Drivers of the Impact of an HIV Cure Intervention in Sub-Saharan Africa

artículo científico publicado en 2016

Immune Monitoring for CMV in Transplantation.

artículo científico publicado en 2018

Immune checkpoint blockade in infectious diseases

artículo científico publicado en 2017

Immune recovery uveitis in an HIV-negative individual†

article

Immune restoration diseases reflect diverse immunopathological mechanisms

scientific article published on October 2009

Immunity in young adult survivors of childhood leukemia is similar to the elderly rather than age-matched controls: Role of cytomegalovirus

artículo científico publicado en 2016

Immunological and Virological Failure after Antiretroviral Therapy Is Associated with Enhanced Peripheral and Thymic Pathogenicity

scholarly article by Ajantha Solomon et al published 15 June 2003 in Journal of Infectious Diseases

Immunopathogenesis of hepatic flare in HIV/hepatitis B virus (HBV)-coinfected individuals after the initiation of HBV-active antiretroviral therapy

artículo científico publicado en 2009

Immunopathogenesis of hepatitis B virus infection

artículo científico publicado en 2006

Immunopathogenesis: role of innate and adaptive immune responses

artículo científico publicado en 2006

Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals

artículo científico publicado en 2017

Impact of alemtuzumab on HIV persistence in an HIV-infected individual on antiretroviral therapy with Sezary syndrome.

artículo científico publicado en 2017

Impact of antiretroviral therapy (ART) timing on chronic immune activation/inflammation and end-organ damage

artículo científico publicado en 2015

Impaired quality of the hepatitis B virus (HBV)-specific T-cell response in human immunodeficiency virus type 1-HBV coinfection

artículo científico publicado en 2009

In memoriam: Professor David Cooper (1949 to 2018).

artículo científico publicado en 2018

In vitro replication phenotype of a novel (-1G) hepatitis B virus variant associated with HIV co-infection

artículo científico publicado en 2012

Incidence of putative HIV superinfection and sexual practices among HIV-infected men who have sex with men.

artículo científico publicado en 2008

Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection

artículo científico publicado en 2014

Increased intrahepatic apoptosis but reduced immune activation in HIV-HBV co-infected patients with advanced immunosuppression

artículo científico publicado en 2011

Individuals with HIV-1 Subtype C Infection and Cryptococcal Meningitis Exhibit Viral Genetic Intermixing of HIV-1 Between Plasma and Cerebrospinal Fluid and a High Prevalence of CXCR4-Using Variants.

artículo científico publicado en 2018

Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging

artículo científico publicado en 2013

Integrated immune dynamics define correlates of COVID-19 severity and antibody responses

artículo científico publicado en 2021

Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4+ T-cell response: a randomized controlled trial

artículo científico publicado en 2011

International AIDS Society global scientific strategy: towards an HIV cure 2016.

scientific article published on 11 July 2016

Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection

artículo científico publicado en 2020

Is Australia prepared for the next pandemic?

artículo científico publicado en 2017

Is specific HIV eradication from the brain possible or needed?

artículo científico

Limitations of dual-fluorescent HIV reporter viruses in a model of pre-activation latency

scientific article published on 01 December 2019

Lipopolysaccharide, immune activation, and liver abnormalities in HIV/hepatitis B virus (HBV)-coinfected individuals receiving HBV-active combination antiretroviral therapy

artículo científico publicado en 2014

Liver Fibrosis Regression Measured by Transient Elastography in Human Immunodeficiency Virus (HIV)-Hepatitis B Virus (HBV)-Coinfected Individuals on Long-Term HBV-Active Combination Antiretroviral Therapy

artículo científico publicado en 2016

Low T-Cell Responses to Mitogen Stimulation Predicts Poor Survival in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

artículo científico publicado en 2017

Major health impact of accelerated aging in young HIV-infected individuals on antiretroviral therapy

artículo científico publicado en 2017

Measuring recent thymic emigrants in blood of normal and HIV-1-infected individuals before and after effective therapy

artículo científico publicado en 1999

Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection

artículo científico publicado en 2017

Modeling of Antilatency Treatment in HIV: What Is the Optimal Duration of Antiretroviral Therapy-Free HIV Remission?

artículo científico publicado en 2017

Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days

artículo científico publicado en 2016

Modeling the Effects of Vorinostat In Vivo Reveals both Transient and Delayed HIV Transcriptional Activation and Minimal Killing of Latently Infected Cells

artículo científico publicado en 2015

Modulation of the CCR5 Receptor/Ligand Axis by Seminal Plasma and the Utility of In Vitro versus In Vivo Models

artículo científico publicado en 2019

Molecular Gymnastics: Mechanisms of HIV-1 Resistance to CCR5 Antagonists and Impact on Virus Phenotypes

artículo científico

Myeloid Dendritic Cells Induce HIV Latency in Proliferating CD4 T Cells

article

Myeloid dendritic cells induce HIV-1 latency in non-proliferating CD4+ T cells

artículo científico publicado en 2013

Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty

artículo científico publicado en 2003

No adverse safety or virological changes 2 years following vorinostat in HIV-infected individuals on antiretroviral therapy

artículo científico publicado en 2017

No difference in the rate of change in telomere length or telomerase activity in HIV-infected patients after three years of darunavir/ritonavir with and without nucleoside analogues in the MONET trial

artículo científico publicado en 2014

No increase in hepatitis B virus (HBV)-specific CD8+ T cells in patients with HIV-1-HBV coinfections following HBV-active highly active antiretroviral therapy

artículo científico publicado en 2010

Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection

artículo científico publicado en 2000

Note from the Editors

artículo científico publicado en 2017

Novel sensitive real-time PCR for quantification of bacterial 16S rRNA genes in plasma of HIV-infected patients as a marker for microbial translocation

artículo científico publicado en 2011

Ongoing Clinical Trials of Human Immunodeficiency Virus Latency-Reversing and Immunomodulatory Agents

artículo científico publicado en 2016

Outcomes following detection of low level plasma HIV RNA in HIV-infected patients previously virologically suppressed on antiretroviral therapy: a retrospective observational study

artículo científico publicado en 2017

PD-1 blockade potentiates HIV latency reversal ex vivo in CD4 T cells from ART-suppressed individuals

article

PD-1 expression in HIV-specific CD8+ T-cells prior to antiretroviral therapy is associated with HIV persistence

article

Paediatric HIV infection: the potential for cure

artículo científico publicado en 2016

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

artículo científico publicado en 2014

Paraneoplastic myasthenia gravis correlates with generation of mature naive CD4+ T cells in thymomas

scientific article published on 01 July 2002

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

artículo científico publicado en 2007

Patterns and causes of suboptimal response to tenofovir-based therapy in individuals coinfected with HIV and hepatitis B virus

artículo científico publicado en 2013

Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy

artículo científico publicado en 2022

Perceptions of HIV cure research among people living with HIV in Australia

artículo científico publicado en 2018

Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy

artículo científico publicado en 2016

Persistent immune activation in chronic HIV infection: do any interventions work?

artículo científico publicado en 2013

Pharmacy adherence measures to assess adherence to antiretroviral therapy: review of the literature and implications for treatment monitoring

artículo científico publicado en 2011

Pharmacy and self-report adherence measures to predict virological outcomes for patients on free antiretroviral therapy in Tamil Nadu, India

artículo científico publicado en 2013

Phase 1 single dose studies to optimize the pharmacokinetics of DG17, a novel HIV-protease inhibitor pro-drug, using sodium bicarbonate and ritonavir

artículo científico publicado en 2008

Plasma But Not Cerebrospinal Fluid Interleukin 7 and Interleukin 5 Levels Pre-Antiretroviral Therapy Commencement Predict Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome

artículo científico publicado en 2017

Plasma levels of soluble CD14 independently predict mortality in HIV infection

artículo científico publicado en 2011

Pneumocystis carinii pneumonia after cessation of secondary prophylaxis in a patient on highly active antiretroviral therapy with a CD4 cell count greater than 200/mm3.

artículo científico publicado en 2001

Polymorphisms in the CD14 and TLR4 genes independently predict CD4+ T-cell recovery in HIV-infected individuals on antiretroviral therapy

artículo científico publicado en 2016

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase 2b Trial

article

Population pharmacokinetics of tenofovir in HIV/HBV co-infected patients

artículo científico publicado en 2015

Post-treatment control in an adult with perinatally acquired HIV following cessation of antiretroviral therapy.

artículo científico publicado en 2017

Preferential infection of dendritic cells during human immunodeficiency virus type 1 infection of blood leukocytes.

artículo científico publicado en 2006

Preliminary assessment of Treponema pallidum-specific IgM antibody detection and a new rapid point-of-care assay for the diagnosis of syphilis in human immunodeficiency virus-1-infected patients

artículo científico publicado en 2010

Prevalence and characterization of lamivudine-resistant hepatitis B virus mutations in HIV-HBV co-infected individuals

artículo científico publicado en 2003

Programmed cell death-1 contributes to the establishment and maintenance of HIV-1 latency

article

Prolonged use of tenofovir in HIV/hepatitis B virus (HBV)-coinfected individuals does not lead to HBV polymerase mutations and is associated with persistence of lamivudine HBV polymerase mutations.

artículo científico publicado en 2009

Quantification of mitochondrial DNA in peripheral blood mononuclear cells and subcutaneous fat using real-time polymerase chain reaction

artículo científico publicado en 2001

Quantifying Adaptive and Innate Immune Responses in HIV-Infected Participants Using a Novel High Throughput Assay

artículo científico publicado en 2016

Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy

artículo científico publicado en 1999

Quantitative HBsAg and HBeAg predict hepatitis B seroconversion after initiation of HAART in HIV-HBV coinfected individuals

artículo científico publicado en 2013

Reduced hepatitis B virus (HBV)-specific CD4+ T-cell responses in human immunodeficiency virus type 1-HBV-coinfected individuals receiving HBV-active antiretroviral therapy

artículo científico publicado en 2005

Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein

artículo científico publicado en 2007

Relationship between Measures of HIV Reactivation and Decline of the Latent Reservoir under Latency-Reversing Agents.

artículo científico publicado en 2017

Relationship of Human Immunodeficiency Virus Viral Load in Cerebrospinal Fluid and Plasma in Patients Co-infected With Cryptococcal Meningitis

artículo científico publicado en 2017

Relative significance of different pathways of immune reconstitution in HIV type 1 infection as estimated by mathematical modeling

artículo científico publicado en 2001

Replication of Hepatitis B Virus and Pathogenesis of Disease

Restoration of replication phenotype of lamivudine-resistant hepatitis B virus mutants by compensatory changes in the "fingers" subdomain of the viral polymerase selected as a consequence of mutations in the overlapping S gene

artículo científico publicado en 2002

Serum hepatitis B surface antigen and hepatitis B e antigen titers: disease phase influences correlation with viral load and intrahepatic hepatitis B virus markers

artículo científico publicado en 2010

Severe hepatitis and prolonged hepatitis B virus-specific CD8 T-cell response after selection of hepatitis B virus YMDD variant in an HIV/hepatitis B virus-co-infected patient

artículo científico publicado en 2004

Sexual transmission of HIV and the law: an Australian medical consensus statement.

artículo científico publicado en 2016

Sexually transmissible infection and HIV management among men who have sex with men with and without HIV: survey of medical practitioners who are members of the Australasian Society for HIV Medicine

article

Shocking HIV out of hiding: where are we with clinical trials of latency reversing agents?

artículo científico publicado en 2016

Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41.

artículo científico publicado en 2014

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study

artículo científico publicado en 2015

Splenectomy associated changes in IgM memory B cells in an adult spleen registry cohort.

artículo científico publicado en 2011

Strategies for an HIV cure: progress and challenges

article

Substantial improvements in performance indicators achieved in a peripheral blood mononuclear cell cryopreservation quality assurance program using single donor samples

artículo científico publicado en 2006

Suppurative thyroiditis due to Nocardia asteroides

artículo científico publicado en 1993

TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection

artículo científico publicado en 2019

Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation

artículo científico publicado en 2013

Targets for intervention to improve virological outcomes for patients receiving free antiretroviral therapy in Tamil Nadu, India

artículo científico publicado en 2013

Ten years of highly active antiretroviral therapy for HIV infection

artículo científico publicado en 2007

The "work" of women when considering and using interventions to reduce mother-to-child transmission (MTCT) of HIV.

artículo científico publicado en 2009

The CD14 C-260T single nucleotide polymorphism (SNP) modulates monocyte/macrophage activation in treated HIV-infected individuals

artículo científico publicado en 2015

The CD16+ Monocyte Subset Is More Permissive to Infection and Preferentially Harbors HIV-1 In Vivo

article

The Sydney Declaration: a call to scale up research

artículo científico publicado en 2007

The anti-HIV activity of entecavir: a multicentre evaluation of lamivudine-experienced and lamivudine-naive patients

artículo científico publicado en 2008

The effect of antiretroviral intensification with dolutegravir on residual virus replication in HIV-infected individuals: a randomised, placebo-controlled, double-blind trial

The end of AIDS: HIV infection as a chronic disease

artículo científico publicado en 2013

The end of HIV: Still a very long way to go, but progress continues

artículo científico publicado en 2017

The evidence for a change in antenatal HIV screening policy in Australia.

artículo científico publicado en 2006

The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets

artículo científico publicado en 2013

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells.

artículo científico publicado en 2009

The pathogenesis of liver disease in the setting of HIV-hepatitis B virus coinfection.

artículo científico publicado en 2009

The pathway to establishing HIV latency is critical to how latency is maintained and reversed.

artículo científico publicado en 2018

The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection.

artículo científico publicado en 2007

The role of SNPs in the α-chain of the IL-7R gene in CD4+ T-cell recovery in HIV-infected African patients receiving suppressive cART.

artículo científico publicado en 2011

The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4(+) T-cells

artículo científico publicado en 2015

The role of bronchoscopy in the diagnosis and treatment of pulmonary disease in HIV-infected patients

article

The role of naïve T-cells in HIV-1 pathogenesis: an emerging key player

artículo científico

The search for an HIV cure: tackling latent infection

artículo científico

The testis and epididymis are productively infected by SIV and SHIV in juvenile macaques during the post-acute stage of infection

artículo científico publicado en 2007

Thymic function in severely immunodeficient HIV type 1-infected patients receiving stable and effective antiretroviral therapy

artículo científico publicado en 2006

Thymic plasmacytoid dendritic cells are susceptible to productive HIV-1 infection and efficiently transfer R5 HIV-1 to thymocytes in vitro

artículo científico publicado en 2011

Towards a cure for HIV--are we making progress?

artículo científico publicado en 2014

Towards a cure for human immunodeficiency virus

artículo científico publicado en 2018

Towards an HIV cure: a global scientific strategy

artículo científico publicado en 2012

Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells

artículo científico publicado en 2016

Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome

artículo científico publicado en 2005

Understanding Factors That Modulate the Establishment of HIV Latency in Resting CD4+ T-Cells In Vitro

artículo científico publicado en 2016

Use of real-time PCR and molecular beacons to detect virus replication in human immunodeficiency virus type 1-infected individuals on prolonged effective antiretroviral therapy

artículo científico publicado en 1999

Variable uptake of recommended interventions to reduce mother-to-child transmission of HIV in Australia, 1982-2005.

artículo científico publicado en 2008

Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease.

artículo científico publicado en 2011

Viral dynamics of hepatitis B virus DNA in human immunodeficiency virus-1-hepatitis B virus coinfected individuals: similar effectiveness of lamivudine, tenofovir, or combination therapy

artículo científico publicado en 2009

Virologic determinants of success after structured treatment interruptions of antiretrovirals in acute HIV-1 infection.

artículo científico publicado en 2008

Virologically suppressed HIV patients show activation of NK cells and persistent innate immune activation.

artículo científico publicado en 2012

Voices of biotech

artículo científico publicado en 2016

What are the barriers to offering HIV testing in an antenatal setting? A national study of obstetricians

artículo científico publicado en 2007