Lista de obras - Glen M. Boyle - Dominio Público Uruguay

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

artículo científico publicado en 2011

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

artículo científico publicado en 2020

Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes

artículo científico publicado en 2021

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.

artículo científico publicado en 2014

Alpha B-Crystallin, a New Independent Marker for Poor Prognosis in Head and Neck Cancer

article

Androgens alter the heterogeneity of small extracellular vesicles and the small RNA cargo in prostate cancer

artículo científico publicado en 2021

Anti-Fibrotic Potential of Tomentosenol A, a Constituent of Cerumen from the Australian Native Stingless Bee, Tetragonula carbonaria

artículo científico publicado en 2022

Antiproliferative and phenotype-transforming antitumor agents derived from cysteine.

artículo científico publicado en 2004

Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death

artículo científico publicado en 2004

Autologous T-cell therapy for cytomegalovirus as a consolidative treatment for recurrent glioblastoma.

artículo científico publicado en 2014

Autophagy is required for stem cell mobilization by G-CSF.

artículo científico publicado en 2015

BRN2 expression increases anoikis resistance in melanoma

artículo científico publicado en 2020

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon

artículo científico publicado en 2019

Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian Aplidium caelestis ⬇️

artículo científico publicado en 2010

Characterization of the Melanoma miRNAome by Deep Sequencing

artículo científico publicado en 2010

Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities

artículo científico publicado en 2008

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

artículo científico publicado en 2018

Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.

artículo científico publicado en 2011

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement

scientific article published on 25 January 2019

Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid.

artículo científico publicado en 2006

EBC-232 and 323: A Structural Conundrum Necessitating Unification of Five In Silico Prediction and Elucidation Methods

scientific article published on 30 August 2020

Effect of novel marine nutraceuticals on IL-1α-mediated TNF-α release from UVB-irradiated human melanocyte-derived cells.

artículo científico publicado en 2011

Evidence for an alternatively spliced MITF exon 2 variant.

artículo científico publicado en 2013

Expression of p53 tumor suppressor protein in sun-exposed skin and associations with sunscreen use and time spent outdoors: a community-based study

artículo científico publicado en 2006

Expression profiling correlates with treatment response in women with advanced serous epithelial ovarian cancer

artículo científico publicado en 2006

Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer

artículo científico publicado en 2009

Furofuran lignans from the Simpson Desert species Eremophila macdonnellii.

artículo científico publicado en 2017

Gene expression profiling in melanoma identifies novel downstream effectors of p14ARF.

artículo científico publicado en 2007

Gene-expression profiling reveals distinct expression patterns for Classic versus Variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma

artículo científico publicado en 2004

H-cadherin expression reduces invasion of malignant melanoma

artículo científico publicado en 2009

Head and neck cancer: past, present and future.

artículo científico publicado en 2006

Histone deacetylase inhibitors and malignant melanoma.

artículo científico publicado en 2005

Histopathological features of clinical perineural invasion of cutaneous squamous cell carcinoma of the head and neck and the potential implications for treatment.

artículo científico publicado en 2013

IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate

artículo científico publicado en 2016

Induction of metallothionein in human skin by routine exposure to sunlight: evidence for a systemic response and enhanced induction at certain body sites

artículo científico publicado en 2003

Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway.

artículo científico publicado en 2006

Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes

article

Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse models ⬇️

artículo científico publicado en 2014

Is Apaf-1 expression frequently abrogated in melanoma?

article

Is alpha-B crystallin an independent marker for prognosis in lung cancer?

artículo científico publicado en 2013

Isoflavonoid photoprotection in mouse and human skin is dependent on metallothionein

artículo científico publicado en 2006

Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5)beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma

artículo científico publicado en 2010

Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian Dysphania Species That Suggests a Putative Biogenetic Link to Zerumbone

scientific article published on 17 April 2020

Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer

artículo científico publicado en 2018

Kunitz type protease inhibitor from the canine tapeworm as a potential therapeutic for melanoma

artículo científico publicado en 2019

Loss of T-cadherin (CDH-13) regulates AKT signaling and desensitizes cells to apoptosis in melanoma

artículo científico publicado en 2013

MITF and BRN2 contribute to metastatic growth after dissemination of melanoma

artículo científico publicado en 2017

Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity

artículo científico publicado en 2008

Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cells

artículo científico publicado en 2015

Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor.

artículo científico publicado en 2011

Microarray expression profiling in melanoma reveals a BRAF mutation signature.

artículo científico publicado en 2004

Microarrays and epidemiology: not the beginning of the end but the end of the beginning...

artículo científico publicado en 2007

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

artículo científico publicado en 2014

Molecular introduction to head and neck cancer (HNSCC) carcinogenesis.

artículo científico publicado en 2004

Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo

artículo científico publicado en 2014

NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.

artículo científico publicado en 2010

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

artículo científico publicado en 2017

Neural cell adhesion molecule expression: no correlation with perineural invasion in cutaneous squamous cell carcinoma of the head and neck.

artículo científico publicado en 2009

New cysteine derivatives with antiproliferative activity on melanoma cells.

artículo científico publicado en 2006

Novel markers for poor prognosis in head and neck cancer.

artículo científico publicado en 2005

Novel mouse model for simulating microsurgical tumor excision with facial nerve preservation

artículo científico publicado en 2015

Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis.

artículo científico publicado en 2007

Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival

artículo científico publicado en 2006

PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.

artículo científico publicado en 2008

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment

artículo científico publicado en 2013

Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp. ⬇️

artículo científico publicado en 2010

Plasticity of melanoma in vivo: murine lesions resulting from Trp53, but not Cdk4 or Arf deregulation, display neural transdifferentiation.

artículo científico publicado en 2013

Potent antimalarial activity of histone deacetylase inhibitor analogues.

artículo científico publicado en 2008

Potential molecular targets for inhibiting bone invasion by oral squamous cell carcinoma: a review of mechanisms.

artículo científico

Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response

artículo científico publicado en 2017

Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma

artículo científico publicado en 2002

REST negatively and ISGF3 positively regulate the human STAT1 gene in melanoma.

artículo científico publicado en 2013

Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion

artículo científico publicado en 2022

Reduced alphaB-crystallin staining in perineural invasion of head and neck cutaneous squamous cell carcinoma

scientific article published on March 2010

Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies.

artículo científico publicado en 2003

SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages

scientific article published on 27 August 2019

Serum omega-3 and omega-6 fatty acids and cutaneous p53 expression in an Australian population

artículo científico publicado en 2011

Spatiotemporal Characterization of the Cellular and Molecular Contributors to Liver Fibrosis in a Murine Hepatotoxic-Injury Model.

artículo científico publicado en 2016

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

artículo científico publicado en 2017

Surfactant protein expression in human skin: evidence and implications.

artículo científico publicado en 2006

Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti-Cancer Activity

artículo científico publicado en 2020

Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis.

artículo científico publicado en 2017

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.

artículo científico publicado en 2015

The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

artículo científico publicado en 2017

The Complement C3a Receptor Contributes to Melanoma Tumorigenesis by Inhibiting Neutrophil and CD4+ T Cell Responses.

artículo científico publicado en 2016

The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement

scientific article published on 01 July 2019

The human genome and gene expression profiling.

artículo científico publicado en 2006

The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.

artículo científico publicado en 2009

Therapy for metastatic melanoma: an overview and update

artículo científico publicado en 2011

Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation

artículo científico publicado en 2010

Transcriptional responses of human melanocytes to solar UV

article

Type I interferons suppress CD4⁺ T-cell-dependent parasite control during blood-stage Plasmodium infection

artículo científico publicado en 2011

UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages.

artículo científico publicado en 2013

Use of kinase inhibitors against schistosomes to improve and broaden praziquantel efficacy

artículo científico publicado en 2020

Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.

artículo científico publicado en 2016

miR-514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma.

artículo científico publicado en 2015

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation

artículo científico publicado en 2010

Lista de obras de Glen M. Boyle

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

ASC modulates CTL cytotoxicity and transplant outcome independent of the inflammasome

Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.

Alpha B-Crystallin, a New Independent Marker for Poor Prognosis in Head and Neck Cancer

Androgens alter the heterogeneity of small extracellular vesicles and the small RNA cargo in prostate cancer

Anti-Fibrotic Potential of Tomentosenol A, a Constituent of Cerumen from the Australian Native Stingless Bee, Tetragonula carbonaria

Antiproliferative and phenotype-transforming antitumor agents derived from cysteine.

Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death

Autologous T-cell therapy for cytomegalovirus as a consolidative treatment for recurrent glioblastoma.

Autophagy is required for stem cell mobilization by G-CSF.

BRN2 expression increases anoikis resistance in melanoma

Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon

Caelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian Aplidium caelestis ⬇️

Characterization of the Melanoma miRNAome by Deep Sequencing

Common strategies to prevent and modulate experimental cerebral malaria in mouse strains with different susceptibilities

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement

Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid.

EBC-232 and 323: A Structural Conundrum Necessitating Unification of Five In Silico Prediction and Elucidation Methods

Effect of novel marine nutraceuticals on IL-1α-mediated TNF-α release from UVB-irradiated human melanocyte-derived cells.

Evidence for an alternatively spliced MITF exon 2 variant.

Expression of p53 tumor suppressor protein in sun-exposed skin and associations with sunscreen use and time spent outdoors: a community-based study

Expression profiling correlates with treatment response in women with advanced serous epithelial ovarian cancer

Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer

Furofuran lignans from the Simpson Desert species Eremophila macdonnellii.

Gene expression profiling in melanoma identifies novel downstream effectors of p14ARF.

Gene-expression profiling reveals distinct expression patterns for Classic versus Variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma

H-cadherin expression reduces invasion of malignant melanoma

Head and neck cancer: past, present and future.

Histone deacetylase inhibitors and malignant melanoma.

Histopathological features of clinical perineural invasion of cutaneous squamous cell carcinoma of the head and neck and the potential implications for treatment.

IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate

Induction of metallothionein in human skin by routine exposure to sunlight: evidence for a systemic response and enhanced induction at certain body sites

Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway.

Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes

Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse models ⬇️

Is Apaf-1 expression frequently abrogated in melanoma?

Is alpha-B crystallin an independent marker for prognosis in lung cancer?

Isoflavonoid photoprotection in mouse and human skin is dependent on metallothionein

Kallikrein-related peptidase 7 promotes multicellular aggregation via the alpha(5)beta(1) integrin pathway and paclitaxel chemoresistance in serous epithelial ovarian carcinoma

Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian Dysphania Species That Suggests a Putative Biogenetic Link to Zerumbone

Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer

Kunitz type protease inhibitor from the canine tapeworm as a potential therapeutic for melanoma

Loss of T-cadherin (CDH-13) regulates AKT signaling and desensitizes cells to apoptosis in melanoma

MITF and BRN2 contribute to metastatic growth after dissemination of melanoma

Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity

Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cells

Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor.

Microarray expression profiling in melanoma reveals a BRAF mutation signature.

Microarrays and epidemiology: not the beginning of the end but the end of the beginning...

Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10

Molecular introduction to head and neck cancer (HNSCC) carcinogenesis.

Multimodal polymer nanoparticles with combined 19F magnetic resonance and optical detection for tunable, targeted, multimodal imaging in vivo

NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

Neural cell adhesion molecule expression: no correlation with perineural invasion in cutaneous squamous cell carcinoma of the head and neck.

New cysteine derivatives with antiproliferative activity on melanoma cells.

Novel markers for poor prognosis in head and neck cancer.

Novel mouse model for simulating microsurgical tumor excision with facial nerve preservation

Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis.

Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival

PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.

Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment

Pestalactams A-C: novel caprolactams from the endophytic fungus Pestalotiopsis sp. ⬇️

Plasticity of melanoma in vivo: murine lesions resulting from Trp53, but not Cdk4 or Arf deregulation, display neural transdifferentiation.

Potent antimalarial activity of histone deacetylase inhibitor analogues.

Potential molecular targets for inhibiting bone invasion by oral squamous cell carcinoma: a review of mechanisms.

Pre-emptive and therapeutic adoptive immunotherapy for nasopharyngeal carcinoma: Phenotype and effector function of T cells impact on clinical response

Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma

REST negatively and ISGF3 positively regulate the human STAT1 gene in melanoma.

Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion

Reduced alphaB-crystallin staining in perineural invasion of head and neck cutaneous squamous cell carcinoma

Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies.

SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages

Serum omega-3 and omega-6 fatty acids and cutaneous p53 expression in an Australian population

Spatiotemporal Characterization of the Cellular and Molecular Contributors to Liver Fibrosis in a Murine Hepatotoxic-Injury Model.

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.