Filtros de búsqueda

Lista de obras de Ignacio A Romero

3D Reconstruction of the Neurovascular Unit Reveals Differential Loss of Cholinergic Innervation in the Cortex and Hippocampus of the Adult Mouse Brain

artículo científico publicado en 2019

A multi-system approach assessing the interaction of anticonvulsants with P-gp

artículo científico publicado en 2013

A novel vascular targeting strategy for brain-derived endothelial cells using a TCR mimic antibody.

artículo científico publicado en 2010

A recombinant inhibitory isoform of vascular endothelial growth factor164/165 aggravates ischemic brain damage in a mouse model of focal cerebral ischemia

artículo científico publicado en 2013

A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions.

artículo científico publicado en 2015

ABC and SLC transporter expression and proton oligopeptide transporter (POT) mediated permeation across the human blood--brain barrier cell line, hCMEC/D3 [corrected]

artículo científico publicado en 2010

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers.

artículo científico publicado en 2017

Action of transcription factors in the control of transferrin receptor expression in human brain endothelium

artículo científico publicado en 2006

Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca2+ influx through cyclic nucleotide-gated channels

artículo científico publicado en 2017

Age-Associated mRNA and miRNA Expression Changes in the Blood-Brain Barrier

scientific article published on 25 June 2019

Age-associated changes in the blood-brain barrier: comparative studies in human and mouse

artículo científico publicado en 2017

Alteration of blood-brain barrier integrity by retroviral infection

artículo científico publicado en 2008

Amyloid-beta-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation.

artículo científico publicado en 2009

Anin VitroStudy ofm-Dinitrobenzene Toxicity on the Cellular Components of the Blood–Brain Barrier, Astrocytes and Endothelial Cells

article

Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.

artículo científico publicado en 2015

BBB on chip: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function.

artículo científico publicado en 2013

Blood-brain barrier-specific properties of a human adult brain endothelial cell line

artículo científico publicado en 2005

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation

artículo científico publicado en 2014

CCL2 binding is CCR2 independent in primary adult human astrocytes

artículo científico publicado en 2011

CCL2 disrupts the adherens junction: implications for neuroinflammation ⬇️

artículo científico publicado el 28 de mayo de 2012

CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro

article

Cannabidiol Enhances the Passage of Lipid Nanocapsules across the Blood-Brain Barrier Both in Vitro and in Vivo

scientific article published on 22 March 2019

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

artículo científico publicado en 2012

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice

artículo científico publicado en 2018

Cerebrospinal fluid dynamics modulation by diet and cytokines in rats

scientific article published on 10 February 2020

Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells

artículo científico publicado en 2003

Characterizing the pathotype of neonatal meningitis causing Escherichia coli (NMEC).

artículo científico publicado en 2015

Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.

artículo científico publicado en 2008

Chemokine transport across human vascular endothelial cells.

artículo científico publicado en 2007

Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

artículo científico publicado en 2001

Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation.

artículo científico publicado en 2017

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

artículo científico publicado en 2017

Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3

artículo científico publicado en 2013

Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models

artículo científico publicado en 2011

Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.

artículo científico publicado en 2014

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

artículo científico publicado en 2008

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier

artículo científico publicado en 2015

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C

artículo científico publicado en 2014

Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development.

artículo científico publicado en 2015

Early metabolic changes during m-dinitrobenzene neurotoxicity and the possible role of oxidative stress

artículo científico publicado en 1995

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown

artículo científico publicado en 2010

Expression and localization of claudins-3 and -12 in transformed human brain endothelium

artículo científico publicado en 2012

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.

artículo científico publicado en 2008

Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment

artículo científico publicado en 2009

Expression of chemokines and their receptors by human brain endothelium: implications for multiple sclerosis.

artículo científico publicado en 2009

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.

artículo científico publicado en 2008

Ezrin and moesin co-localise with ICAM-1 in brain endothelial cells but are not directly associated

artículo científico publicado en 2002

F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: effects of cyclic AMP and astrocytic factors

artículo científico publicado en 1997

Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro

artículo científico publicado en 2011

Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro

artículo científico publicado en 2013

Hepatitis C virus infects the endothelial cells of the blood-brain barrier

artículo científico publicado en 2011

High-Density Lipoproteins Limit Neutrophil-Induced Damage to the Blood–Brain Barrier in Vitro ⬇️

artículo científico publicado el 9 de enero de 2013

Human brain endothelial cells are responsive to adenosine receptor activation ⬇️

artículo científico publicado el 17 de febrero de 2011

Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells

artículo científico publicado en 2008

Identification of an essential endogenous regulator of blood–brain barrier integrity, and its pathological and therapeutic implications ⬇️

artículo científico publicado el 31 de diciembre de 2012

Identification of peptide ligands for targeting to the blood-brain barrier

artículo científico publicado en 2010

Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies

artículo científico publicado en 2007

Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier

artículo científico publicado en 2012

Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4.

artículo científico publicado en 2015

Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors

artículo científico publicado en 2015

In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.

artículo científico publicado en 2016

Lamotrigine is a substrate for OCT1 in brain endothelial cells

artículo científico publicado en 2011

Localization and mobility of glucose-coated gold nanoparticles within the brain.

artículo científico publicado en 2016

Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis

artículo científico publicado en 2017

Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.

artículo científico publicado en 2009

Metabolic and permeability changes caused by thiamine deficiency in immortalized rat brain microvessel endothelial cells

artículo científico publicado en 1997

Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells

artículo científico publicado en 2009

Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells

artículo científico publicado en 2016

MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium

artículo científico publicado en 2017

MicroRNA-155 contributes to shear-resistant leukocyte adhesion to human brain endothelium in vitro

artículo científico publicado en 2016

MicroRNA-155 negatively affects blood–brain barrier function during neuroinflammation

artículo científico publicado en 2014

MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis.

artículo científico publicado en 2013

Microparticles in multiple sclerosis and clinically isolated syndrome: effect on endothelial barrier function

artículo científico publicado en 2014

Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies

artículo científico publicado en 2009

Molecular cytogenetic characterization of the human cerebral microvessel endothelial cell line hCMEC/D3.

artículo científico publicado en 2009

Nanoparticle formulation improves the anticonvulsant effect of clonazepam on the pentylenetetrazole-induced seizures: behavior and electroencephalogram.

artículo científico publicado en 2014

Oxidative stress affects the junctional integrity of retinal pigment epithelial cells.

artículo científico publicado en 2004

P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta

artículo científico publicado en 2009

PPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer's disease: in vitro and in vivo studies

artículo científico publicado en 2018

Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles

artículo científico publicado en 2013

Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line

artículo científico publicado en 2009

Permeability of PEGylated immunoarsonoliposomes through in vitro blood brain barrier-medulloblastoma co-culture models for brain tumor therapy

artículo científico publicado en 2014

Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123.

artículo científico publicado en 2009

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier

artículo científico publicado en 2016

Protective effect of the multitarget compound DPH-4 on human SSAO/VAP-1-expressing hCMEC/D3 cells under oxygen-glucose deprivation conditions: an in vitro experimental model of cerebral ischaemia.

artículo científico publicado en 2015

Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3

artículo científico publicado en 2011

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

artículo científico publicado en 2007

Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation

artículo científico publicado en 2016

Regulation of cerebral endothelial cell morphology by extracellular calcium

artículo científico publicado en 2007

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

artículo científico publicado en 2009

Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells

artículo científico publicado en 2012

Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability.

artículo científico publicado en 2003

Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis.

artículo científico publicado en 2015

Signaling mechanism of extracellular RNA in endothelial cells

artículo científico publicado en 2009

Solid lipid nanoparticles as a vehicle for brain-targeted drug delivery: two new strategies of functionalization with apolipoprotein E.

artículo científico publicado en 2015

Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis

artículo científico publicado en 2013

Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS.

artículo científico publicado en 2013

Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia

artículo científico publicado en 2013

The association of statins plus LDL receptor-targeted liposome-encapsulated doxorubicin increases in vitro drug delivery across blood-brain barrier cells.

artículo científico publicado en 2012

The blood-brain barrier in multiple sclerosis: microRNAs as key regulators.

artículo científico publicado en 2015

The hCMEC/D3 cell line as a model of the human blood brain barrier

artículo científico

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

artículo científico publicado en 2008

The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine

artículo científico publicado en 2012

The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family

artículo científico publicado en 2014

The role of perivascular innervation and neurally mediated vasoreactivity in the pathophysiology of Alzheimer's disease.

artículo científico publicado en 2017

The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood-brain barrier: evidence for involvement of breast cancer resistance protein

artículo científico publicado en 2011

Toxic effects of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alanine

artículo científico publicado en 1998

Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro

artículo científico publicado en 2012

Transcriptional control of occludin expression in vascular endothelia: regulation by Sp3 and YY1.

artículo científico publicado en 2009

Transcriptional control of the multi-drug transporter ABCB1 by transcription factor Sp3 in different human tissues

artículo científico publicado en 2012

Transendothelial permeability changes induced by free radicals in an in vitro model of the blood-brain barrier

artículo científico publicado en 1999

Transport of Gold Nanoparticles by Vascular Endothelium from Different Human Tissues

artículo científico publicado en 2016

Transporting therapeutics across the blood-brain barrier

artículo científico publicado en 1996

Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?

artículo científico publicado en 2016

Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium ⬇️

artículo científico publicado el 18 de diciembre de 2010

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

artículo científico publicado en 2009

Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line

artículo científico publicado en 2010

[EXPRESS] Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infra-orbital blood-nerve barrier following chronic constriction injury?

artículo científico publicado en 2017

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda