Lista de obras - Mario Chiariello - Dominio Público Uruguay

Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy

artículo científico publicado en 2018

Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene.

artículo científico publicado en 2006

Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex

artículo científico publicado en 1999

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B.

artículo científico publicado en 2017

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier

artículo científico publicado en 2017

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells

artículo científico publicado en 2015

Cloning and expression analysis of the murine Rab7 cDNA.

artículo científico publicado en 1995

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

artículo científico publicado en 2017

Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2 ⬇️

artículo científico publicado el 6 de mayo de 2013

Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693.

artículo científico publicado en 2014

EGFR-Targeted Magnetic Nanovectors Recognize, in Vivo, Head and Neck Squamous Cells Carcinoma-Derived Tumors.

artículo científico publicado en 2017

Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity.

artículo científico publicado en 2010

Genetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog.

artículo científico publicado en 1998

Growth factor transduction pathways: paradigm of anti-neoplastic targeted therapy

artículo científico publicado en 2014

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction

artículo científico publicado en 2020

Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma

artículo científico publicado en 2016

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

artículo científico

Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).

artículo científico publicado en 1999

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process

artículo científico publicado en 2018

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

artículo científico publicado en 2015

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors.

artículo científico publicado en 2016

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins ⬇️

artículo científico publicado el 4 de septiembre de 2012

Molecular cloning and expression analysis of the human Rab7 GTP-ase complementary deoxyribonucleic acid

scientific journal article

Molecular insights to the bioactive form of BV02, a reference inhibitor of 14-3-3σ protein-protein interactions

artículo científico publicado en 2015

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

artículo científico publicado en 2000

NCOA4 Deficiency Impairs Systemic Iron Homeostasis

artículo científico publicado en 2016

One drug for two targets: Biological evaluation of antiretroviral agents endowed with antiproliferative activity

artículo científico publicado en 2017

Plasmin-Binding Tripeptide-Decorated Liposomes Loading Pyrazolo[3,4-d]pyrimidines for Targeting Hepatocellular Carcinoma

artículo científico publicado en 2018

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

artículo científico publicado en 2017

Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.

artículo científico publicado en 2017

Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cells

scientific journal article

Regulation of c-myc expression by PDGF through Rho GTPases.

artículo científico publicado en 2001

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.

artículo científico publicado en 2001

Regulation of mitogen-activated protein kinases by G-protein-coupled receptors

artículo científico publicado en 2002

Role of the small GTPase Rab7 in the late endocytic pathway.

artículo científico publicado en 1997

Selective transcription and cellular proliferation induced by PDGF require histone deacetylase activity

artículo científico publicado en 2006

Straightforward synthesis of a novel ring-fused pyrazole-lactam and in vitro cytotoxic activity on cancer cell lines.

artículo científico publicado en 2016

Structure prediction and validation of the ERK8 kinase domain

artículo científico publicado en 2013

Surface chemistry and entrapment of magnesium nanoparticles into polymeric micelles: a highly biocompatible tool for photothermal therapy

artículo científico publicado en 2014

The platelet-derived growth factor controls c-myc expression through a JNK- and AP-1-dependent signaling pathway.

artículo científico publicado en 2003

The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.

artículo científico publicado en 2004

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

artículo científico publicado en 1995

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Mario Chiariello

Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy

Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene.

Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B.

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier

Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells

Cloning and expression analysis of the murine Rab7 cDNA.

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2 ⬇️

Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693.

EGFR-Targeted Magnetic Nanovectors Recognize, in Vivo, Head and Neck Squamous Cells Carcinoma-Derived Tumors.

Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity.

Genetic mapping of the mouse Rab7 gene and pseudogene and of the human RAB7 homolog.

Growth factor transduction pathways: paradigm of anti-neoplastic targeted therapy

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction

Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors.

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins ⬇️

Molecular cloning and expression analysis of the human Rab7 GTP-ase complementary deoxyribonucleic acid

Molecular insights to the bioactive form of BV02, a reference inhibitor of 14-3-3σ protein-protein interactions

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

NCOA4 Deficiency Impairs Systemic Iron Homeostasis

One drug for two targets: Biological evaluation of antiretroviral agents endowed with antiproliferative activity

Plasmin-Binding Tripeptide-Decorated Liposomes Loading Pyrazolo[3,4-d]pyrimidines for Targeting Hepatocellular Carcinoma

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

Pyrazolo[3,4-d]pyrimidines-loaded human serum albumin (HSA) nanoparticles: Preparation, characterization and cytotoxicity evaluation against neuroblastoma cell line.

Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cells

Regulation of c-myc expression by PDGF through Rho GTPases.

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.

Regulation of mitogen-activated protein kinases by G-protein-coupled receptors

Role of the small GTPase Rab7 in the late endocytic pathway.

Selective transcription and cellular proliferation induced by PDGF require histone deacetylase activity

Straightforward synthesis of a novel ring-fused pyrazole-lactam and in vitro cytotoxic activity on cancer cell lines.

Structure prediction and validation of the ERK8 kinase domain

Surface chemistry and entrapment of magnesium nanoparticles into polymeric micelles: a highly biocompatible tool for photothermal therapy

The platelet-derived growth factor controls c-myc expression through a JNK- and AP-1-dependent signaling pathway.

The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)