Lista de obras - Liesbeth Vandenput - Dominio Público Uruguay

A decade of FRAX: how has it changed the management of osteoporosis?

scientific article published on 11 February 2020

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

artículo científico publicado en 2012

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A semiparametric Bayesian approach for structural equation models

artículo científico publicado en 2010

ACE inhibitor use was associated with lower serum dehydroepiandrosterone concentrations in older men

artículo científico publicado en 2010

An aged rat model of partial androgen deficiency: prevention of both loss of bone and lean body mass by low-dose androgen replacement

artículo científico publicado en 2000

Androgens and Bone

Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men.

artículo científico publicado en 2007

Androgens and osteoporosis.

artículo científico publicado en 2000

Assessment of gene-by-sex interaction effect on bone mineral density

artículo científico publicado en 2012

Association of SRD5A2 variants and serum androstane-3alpha,17beta-diol glucuronide concentration in Chinese elderly men.

artículo científico publicado en 2010

Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men.

artículo científico publicado en 2009

BMD-Related Genetic Risk Scores Predict Site-Specific Fractures as Well as Trabecular and Cortical Bone Microstructure

scientific article published on 01 April 2020

Bone and muscle protective potential of the prostate-sparing synthetic androgen 7alpha-methyl-19-nortestosterone: evidence from the aged orchidectomized male rat model

artículo científico publicado en 2005

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

artículo científico publicado en 2017

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

artículo científico publicado en 2013

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

artículo científico publicado en 2010

Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer

artículo científico publicado en 2008

Comparisons of immunoassay and mass spectrometry measurements of serum estradiol levels and their influence on clinical association studies in men.

artículo científico publicado en 2013

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

DHEA and mortality: what is the nature of the association?

artículo científico publicado en 2014

Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.

artículo científico publicado en 2014

Disentangling the genetics of lean mass

article

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

artículo científico publicado en 2014

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

artículo científico publicado en 2011

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Estrogens as regulators of bone health in men.

scientific article published on 16 June 2009

Evidence for geographical and racial variation in serum sex steroid levels in older men.

artículo científico publicado en 2010

Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone

scientific journal article

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men

artículo científico publicado en 2019

Genetic Determinants of Circulating Estrogen Levels, and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

artículo científico publicado en 2018

Genetic determinants of serum testosterone concentrations in men.

artículo científico publicado en 2011

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

artículo científico publicado en 2013

Genetic evidence of assortative mating in humans

article

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.

artículo científico publicado en 2008

Genetics of endocrine disorders in the era of genome-wide association studies.

artículo científico publicado en 2013

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone

artículo científico publicado en 2010

Genome-wide association studies on serum sex steroid levels

artículo científico

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

artículo científico publicado en 2014

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

artículo científico publicado en 2018

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

artículo científico publicado en 2012

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

artículo científico publicado en 2016

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men

artículo científico publicado en 2015

High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden

artículo científico publicado en 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Hydroxysteroid (17β)-dehydrogenase 1-deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production

artículo científico publicado en 2015

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Limited clinical utility of a genetic risk score for the prediction of fracture risk in elderly subjects

artículo científico publicado en 2015

Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study.

artículo científico publicado en 2011

Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study

scholarly article by Claes Ohlsson et al published 30 March 2017 in Journal of Bone and Mineral Research

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study

artículo científico publicado en 2017

Low serum levels of dehydroepiandrosterone sulfate predict all-cause and cardiovascular mortality in elderly Swedish men.

artículo científico publicado en 2010

Low serum testosterone and estradiol predict mortality in elderly men.

artículo científico publicado en 2009

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

artículo científico publicado en 2017

Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry

artículo científico publicado en 2015

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels

artículo científico publicado en 2014

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

artículo científico publicado en 2012

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

artículo científico publicado en 2019

Multi-ethnic fine-mapping of 14 central adiposity loci

artículo científico publicado en 2014

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

artículo científico publicado en 2016

OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.

artículo científico publicado en 2010

Older men with low serum IGF-1 have an increased risk of incident fractures: the MrOS Sweden study

artículo científico publicado en 2011

Older men with low serum estradiol and high serum SHBG have an increased risk of fractures

artículo científico publicado en 2008

Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter

artículo científico publicado en 2009

Preventing osteoporotic fractures with antiresorptive therapy: implications of microarchitectural changes

artículo científico publicado en 2004

Pubertal timing and adult fracture risk in men: A population-based cohort study

scientific article published on 02 December 2019

Quality control and conduct of genome-wide association meta-analyses

artículo científico publicado en 2014

Reply

Reversing sex steroid deficiency and optimizing skeletal development in the adolescent with gonadal failure

artículo científico publicado en 2005

Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model

artículo científico publicado en 2004

SHBGGene Promoter Polymorphisms in Men Are Associated with Serum Sex Hormone-Binding Globulin, Androgen and Androgen Metabolite Levels, and Hip Bone Mineral Density

artículo científico publicado en 2006

Serum estradiol associates with blood hemoglobin in elderly men: the MrOS Sweden study

artículo científico publicado en 2014

Serum estradiol is associated with lean mass in elderly Swedish men.

artículo científico publicado en 2010

Serum estradiol levels are inversely associated with cortical porosity in older men.

artículo científico publicado en 2014

Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men.

artículo científico publicado en 2007

Sex steroid actions in male bone

artículo científico publicado en 2014

Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y).

artículo científico publicado en 2007

Sex steroid metabolism in the regulation of bone health in men.

artículo científico publicado en 2010

Sex steroids and bone health in men.

artículo científico publicado en 2012

Sex steroids and bone health in older Chinese men

artículo científico publicado en 2011

Skeletal effects of estrogen deficiency as induced by an aromatase inhibitor in an aged male rat model

article

Sleep Duration and Disturbances Were Associated With Testosterone Level, Muscle Mass, and Muscle Strength--A Cross-Sectional Study in 1274 Older Men.

artículo científico publicado en 2015

Testosterone but not estradiol level is positively related to muscle strength and physical performance independent of muscle mass: a cross-sectional study in 1489 older men

scholarly article by Tung Wai Auyeung et al published May 2011 in European Journal of Endocrinology

Testosterone prevents orchidectomy-induced bone loss in estrogen receptor-alpha knockout mice

artículo científico publicado en 2001

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Uridine Diphosphate Glucuronosyltransferase 2B15 D85Y and 2B17 Deletion Polymorphisms Predict the Glucuronidation Pattern of Androgens and Fat Mass in Men

The estrogen receptor ligand ICI 182,780 does not impair the bone-sparing effects of testosterone in the young orchidectomized rat model

artículo científico publicado en 2002

The gut microbiota is a major regulator of androgen metabolism in intestinal contents

artículo científico publicado en 2019

The role of IGF-1 for fracture risk in men.

artículo científico publicado en 2012

The role of estrogens for male bone health

artículo científico publicado en 2009

Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan

Use of age-dependent FRAX-based intervention thresholds for Singapore

scientific article published on 22 July 2020

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

artículo científico publicado en 2012

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

artículo científico publicado en 2015

Lista de obras de Liesbeth Vandenput

A decade of FRAX: how has it changed the management of osteoporosis?

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

A semiparametric Bayesian approach for structural equation models

ACE inhibitor use was associated with lower serum dehydroepiandrosterone concentrations in older men

An aged rat model of partial androgen deficiency: prevention of both loss of bone and lean body mass by low-dose androgen replacement

Androgens and Bone

Androgens and glucuronidated androgen metabolites are associated with metabolic risk factors in men.

Androgens and osteoporosis.

Assessment of gene-by-sex interaction effect on bone mineral density

Association of SRD5A2 variants and serum androstane-3alpha,17beta-diol glucuronide concentration in Chinese elderly men.

Association of genetic variations in aromatase gene with serum estrogen and estrogen/testosterone ratio in Chinese elderly men.

BMD-Related Genetic Risk Scores Predict Site-Specific Fractures as Well as Trabecular and Cortical Bone Microstructure

Bone and muscle protective potential of the prostate-sparing synthetic androgen 7alpha-methyl-19-nortestosterone: evidence from the aged orchidectomized male rat model

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer

Comparisons of immunoassay and mass spectrometry measurements of serum estradiol levels and their influence on clinical association studies in men.

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

DHEA and mortality: what is the nature of the association?

Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart disease events in elderly men.

Disentangling the genetics of lean mass

Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT.

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Estrogens as regulators of bone health in men.

Evidence for geographical and racial variation in serum sex steroid levels in older men.

Evidence from the aged orchidectomized male rat model that 17beta-estradiol is a more effective bone-sparing and anabolic agent than 5alpha-dihydrotestosterone

Evidence of a Causal Effect of Estradiol on Fracture Risk in Men

Genetic Determinants of Circulating Estrogen Levels, and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

Genetic determinants of serum testosterone concentrations in men.

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

Genetic evidence of assortative mating in humans

Genetic studies of body mass index yield new insights for obesity biology

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Genetic variations in sex steroid-related genes as predictors of serum estrogen levels in men.

Genetics of endocrine disorders in the era of genome-wide association studies.

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone

Genome-wide association studies on serum sex steroid levels

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men

High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Hydroxysteroid (17β)-dehydrogenase 1-deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Limited clinical utility of a genetic risk score for the prediction of fracture risk in elderly subjects

Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study.

Low Serum DHEAS Predicts Increased Fracture Risk in Older Men: The MrOS Sweden Study

Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study

Low serum levels of dehydroepiandrosterone sulfate predict all-cause and cardiovascular mortality in elderly Swedish men.

Low serum testosterone and estradiol predict mortality in elderly men.

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

Measurement of a Comprehensive Sex Steroid Profile in Rodent Serum by High-Sensitive Gas Chromatography-Tandem Mass Spectrometry

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

Multi-ethnic fine-mapping of 14 central adiposity loci

New genetic loci link adipose and insulin biology to body fat distribution

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.

Older men with low serum IGF-1 have an increased risk of incident fractures: the MrOS Sweden study

Older men with low serum estradiol and high serum SHBG have an increased risk of fractures

Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter