Lista de obras - Simon C Lovell - Dominio Público Uruguay

Ab initio construction of polypeptide fragments: efficient generation of accurate, representative ensembles

artículo científico publicado en 2003

Abrogation of HMX1 function causes rare oculoauricular syndrome associated with congenital cataract, anterior segment dysgenesis, and retinal dystrophy

artículo científico publicado en 2015

Agnathia-otocephaly complex and asymmetric velopharyngeal insufficiency due to an in-frame duplication in OTX2.

artículo científico publicado en 2015

All duplicates are not equal: the difference between small-scale and genome duplication

artículo científico publicado en 2007

Alternative splicing and protein interaction data sets

artículo científico publicado en 2013

An algorithm for predicting protein-protein interaction sites: Abnormally exposed amino acid residues and secondary structure elements

artículo científico publicado en 2006

An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network

artículo científico publicado en 2007

An integrated view of molecular coevolution in protein-protein interactions

artículo científico publicado en 2010

Analysis of genetic interaction networks shows that alternatively spliced genes are highly versatile

artículo científico publicado en 2013

Analysis of synthetic lethality reveals genetic interactions between the GTPase Snu114p and snRNAs in the catalytic core of the Saccharomyces cerevisiae spliceosome

artículo científico publicado en 2009

Andante: reducing side-chain rotamer search space during comparative modeling using environment-specific substitution probabilities

artículo científico publicado en 2007

Are non‐functional, unfolded proteins (‘junk proteins’) common in the genome? ⬇️

artículo científico publicado el 20 de noviembre de 2003

Artefacts and biases affecting the evaluation of scoring functions on decoy sets for protein structure prediction.

artículo científico publicado en 2009

Binding interface change and cryptic variation in the evolution of protein-protein interactions.

artículo científico publicado en 2016

Bioinformatics: from molecules to systems. A discussion meeting held at The Royal Society on 4 and 5 April 2005.

artículo científico publicado en 2005

CHORAL: a differential geometry approach to the prediction of the cores of protein structures

artículo científico publicado en 2005

Characterization and prediction of haploinsufficiency using systems-level gene properties in yeast

artículo científico publicado en 2013

Characterization of protein-protein interaction interfaces from a single species

artículo científico publicado en 2011

Constraints from protein structure and intra-molecular coevolution influence the fitness of HIV-1 recombinants.

artículo científico publicado en 2014

Constraints on HIV-1 diversity from protein structure

artículo científico publicado en 2010

Cooperativity in Bacillus stearothermophilus pyruvate kinase

Correlation of microsynteny conservation and disease gene distribution in mammalian genomes

artículo científico publicado en 2009

Covariation Is a Poor Measure of Molecular Coevolution.

artículo científico publicado en 2015

Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics

artículo científico publicado en 2003

Cyclic AMP potentiates receptor-stimulated phosphoinositide hydrolysis in human neuroepithelioma cells

artículo científico publicado en 1992

Determining the evolutionary history of gene families

artículo científico publicado en 2011

Distinguishing structural and functional restraints in evolution in order to identify interaction sites

artículo científico publicado en 2004

Diversification at transcription factor binding sites within a species and the implications for environmental adaptation

artículo científico publicado en 2011

DupliPHY-Web: a web server for DupliPHY and DupliPHY-ML.

artículo científico publicado en 2014

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains

artículo científico publicado en 2007

Ebolavirus is evolving but not changing: No evidence for functional change in EBOV from 1976 to the 2014 outbreak.

artículo científico publicado en 2015

Erbb2 is required for cardiac atrial electrical activity during development

artículo científico publicado en 2014

Evolution in protein interaction networks: co-evolution, rewiring and the role of duplication

artículo científico publicado en 2009

Evolvability of Yeast Protein–Protein Interaction Interfaces

scientific article published on 01 April 2012

Gene duplication and environmental adaptation within yeast populations

artículo científico publicado en 2010

Generating, Maintaining, and Exploiting Diversity in a Memetic Algorithm for Protein Structure Prediction.

artículo científico publicado en 2016

Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

artículo científico publicado en 2004

Inferring gene family histories in yeast identifies lineage specific expansions

artículo científico publicado en 2014

Interactions between Kar2p and its nucleotide exchange factors Sil1p and Lhs1p are mechanistically distinct

artículo científico publicado en 2010

Modular biological function is most effectively captured by combining molecular interaction data types

artículo científico publicado en 2013

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

artículo científico publicado en 2012

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

artículo científico publicado en 2012

Mutations in non-acid patch residues disrupt H2A.Z's association with chromatin through multiple mechanisms.

artículo científico publicado en 2013

Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability

artículo científico publicado en 2013

Properties of polyproline II, a secondary structure element implicated in protein-protein interactions

artículo científico publicado en 2005

Protein interactions from complexes: a structural perspective

artículo científico publicado en 2006

Protein-protein interaction networks and biology--what's the connection?

artículo científico publicado en 2008

Quantitative analysis and prediction of curvature in leucine-rich repeat proteins

artículo científico publicado en 2009

Rapid functional and evolutionary changes follow gene duplication in yeast.

artículo científico publicado en 2017

Secondary structure assignment that accurately reflects physical and evolutionary characteristics.

artículo científico publicado en 2005

Sequence-structure homology recognition by iterative alignment refinement and comparative modeling.

artículo científico publicado en 2001

Sequencing and characterisation of rearrangements in three S. pastorianus strains reveals the presence of chimeric genes and gives evidence of breakpoint reuse

artículo científico publicado en 2014

Specificity in protein interactions and its relationship with sequence diversity and coevolution

artículo científico publicado en 2007

Structure validation by Calpha geometry: phi,psi and Cbeta deviation

artículo científico publicado en 2003

Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature

artículo científico publicado en 2011

The dual role of fragments in fragment-assembly methods for de novo protein structure prediction

artículo científico publicado en 2011

The effect of sequence evolution on protein structural divergence.

artículo científico publicado en 2009

The leucine-rich repeat structure.

artículo científico publicado en 2008

The origins of the evolutionary signal used to predict protein-protein interactions

artículo científico publicado en 2012

The role of protein interactions in mediating essentiality and synthetic lethality

artículo científico publicado en 2013

The role of small in-frame insertions/deletions in inherited eye disorders and how structural modelling can help estimate their pathogenicity.

artículo científico publicado en 2016

Toward a detailed understanding of search trajectories in fragment assembly approaches to protein structure prediction

artículo científico publicado en 2016

Using knowledge of protein structural constraints to predict the evolution of HIV-1.

artículo científico publicado en 2011

Lista de obras de Simon C Lovell

Ab initio construction of polypeptide fragments: efficient generation of accurate, representative ensembles

Abrogation of HMX1 function causes rare oculoauricular syndrome associated with congenital cataract, anterior segment dysgenesis, and retinal dystrophy

Agnathia-otocephaly complex and asymmetric velopharyngeal insufficiency due to an in-frame duplication in OTX2.

All duplicates are not equal: the difference between small-scale and genome duplication

Alternative splicing and protein interaction data sets

An algorithm for predicting protein-protein interaction sites: Abnormally exposed amino acid residues and secondary structure elements

An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network

An integrated view of molecular coevolution in protein-protein interactions

Analysis of genetic interaction networks shows that alternatively spliced genes are highly versatile

Analysis of synthetic lethality reveals genetic interactions between the GTPase Snu114p and snRNAs in the catalytic core of the Saccharomyces cerevisiae spliceosome

Andante: reducing side-chain rotamer search space during comparative modeling using environment-specific substitution probabilities

Are non‐functional, unfolded proteins (‘junk proteins’) common in the genome? ⬇️

Artefacts and biases affecting the evaluation of scoring functions on decoy sets for protein structure prediction.

Binding interface change and cryptic variation in the evolution of protein-protein interactions.

Bioinformatics: from molecules to systems. A discussion meeting held at The Royal Society on 4 and 5 April 2005.

CHORAL: a differential geometry approach to the prediction of the cores of protein structures

Characterization and prediction of haploinsufficiency using systems-level gene properties in yeast

Characterization of protein-protein interaction interfaces from a single species

Constraints from protein structure and intra-molecular coevolution influence the fitness of HIV-1 recombinants.

Constraints on HIV-1 diversity from protein structure

Cooperativity in Bacillus stearothermophilus pyruvate kinase

Correlation of microsynteny conservation and disease gene distribution in mammalian genomes

Covariation Is a Poor Measure of Molecular Coevolution.

Crystal structures of engrailed homeodomain mutants: implications for stability and dynamics

Cyclic AMP potentiates receptor-stimulated phosphoinositide hydrolysis in human neuroepithelioma cells

Determining the evolutionary history of gene families

Distinguishing structural and functional restraints in evolution in order to identify interaction sites

Diversification at transcription factor binding sites within a species and the implications for environmental adaptation

DupliPHY-Web: a web server for DupliPHY and DupliPHY-ML.

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains

Ebolavirus is evolving but not changing: No evidence for functional change in EBOV from 1976 to the 2014 outbreak.

Erbb2 is required for cardiac atrial electrical activity during development

Evolution in protein interaction networks: co-evolution, rewiring and the role of duplication

Evolvability of Yeast Protein–Protein Interaction Interfaces

Gene duplication and environmental adaptation within yeast populations

Generating, Maintaining, and Exploiting Diversity in a Memetic Algorithm for Protein Structure Prediction.

Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

Inferring gene family histories in yeast identifies lineage specific expansions

Interactions between Kar2p and its nucleotide exchange factors Sil1p and Lhs1p are mechanistically distinct

Modular biological function is most effectively captured by combining molecular interaction data types

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

Mutations in non-acid patch residues disrupt H2A.Z's association with chromatin through multiple mechanisms.

Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability

Properties of polyproline II, a secondary structure element implicated in protein-protein interactions

Protein interactions from complexes: a structural perspective

Protein-protein interaction networks and biology--what's the connection?

Quantitative analysis and prediction of curvature in leucine-rich repeat proteins

Rapid functional and evolutionary changes follow gene duplication in yeast.

Secondary structure assignment that accurately reflects physical and evolutionary characteristics.

Sequence-structure homology recognition by iterative alignment refinement and comparative modeling.

Sequencing and characterisation of rearrangements in three S. pastorianus strains reveals the presence of chimeric genes and gives evidence of breakpoint reuse

Specificity in protein interactions and its relationship with sequence diversity and coevolution

Structure validation by Calpha geometry: phi,psi and Cbeta deviation

Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature

The dual role of fragments in fragment-assembly methods for de novo protein structure prediction

The effect of sequence evolution on protein structural divergence.

The leucine-rich repeat structure.

The origins of the evolutionary signal used to predict protein-protein interactions

The role of protein interactions in mediating essentiality and synthetic lethality

The role of small in-frame insertions/deletions in inherited eye disorders and how structural modelling can help estimate their pathogenicity.

Toward a detailed understanding of search trajectories in fragment assembly approaches to protein structure prediction

Using knowledge of protein structural constraints to predict the evolution of HIV-1.