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Lista de obras de Cristen J. Willer

A first stage genome-wide screen for regions shared identical-by-descent in hutterite families with multiple sclerosis

artículo científico publicado en 2008

A genome scan for genes underlying adult body size differences between Central African hunter-gatherers and farmers

scientific article published on 14 July 2018

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide scan in forty large pedigrees with multiple sclerosis

artículo científico publicado en 2007

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

artículo científico publicado en 2021

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

Accurate local-ancestry inference in exome-sequenced admixed individuals via off-target sequence reads

artículo científico publicado en 2013

An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group

artículo científico publicado en 2004

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

artículo científico publicado en 2010

Association between microchimerism and multiple sclerosis in Canadian twins.

artículo científico publicado en 2006

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

artículo científico publicado en 2014

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

artículo científico publicado en 2019

Author Correction: Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

artículo científico publicado en 2020

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

artículo científico publicado en 2020

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

scientific article published on 30 July 2018

Biological and clinical insights from genetics of insomnia symptoms

scientific article published on 25 February 2019

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

artículo científico publicado en 2021

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Coding variants in and increase risk of atrial fibrillation

scientific article published on 12 June 2018

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 30 loci contribute to polygenic dyslipidemia

artículo científico publicado en 2009

Common variants in the GDF5-UQCC region are associated with variation in human height

artículo científico publicado en 2008

Common variants near MC4R are associated with fat mass, weight and risk of obesity

artículo científico publicado en 2008

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals

artículo científico publicado en 2011

Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance

artículo científico publicado en 2005

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

artículo científico publicado en 2009

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

artículo científico publicado en 2018

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

artículo científico publicado en 2020

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

artículo científico publicado en 2014

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

artículo científico publicado en 2018

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis

artículo científico publicado en 2001

Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

artículo científico publicado en 2017

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

artículo científico publicado en 2020

Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese

artículo científico publicado en 2015

Exome-wide association study of plasma lipids in >300,000 individuals

artículo científico publicado en 2017

Exploring and visualizing large-scale genetic associations by using PheWeb

artículo científico publicado en 2020

Finding genes and variants for lipid levels after genome-wide association analysis

artículo científico publicado en 2012

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

artículo científico publicado en 2020

Genetic evidence of assortative mating in humans

article

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

artículo científico publicado en 2018

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

artículo científico publicado en 2022

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic susceptibility to MS: a second stage analysis in Canadian MS families

artículo científico publicado en 2001

Genetically determined height and coronary artery disease

artículo científico publicado en 2015

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

artículo científico publicado en 2018

Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

artículo científico publicado en 2017

Genome-wide analysis yields new loci associating with aortic valve stenosis

artículo científico publicado en 2018

Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes

artículo científico publicado en 2019

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

artículo científico publicado en 2009

Genome-wide association study identifies eight loci associated with blood pressure

artículo científico publicado en 2009

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

artículo científico publicado en 2020

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomic inflation factors under polygenic inheritance

artículo científico publicado en 2011

Genotype imputation

artículo científico publicado en 2009

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels.

artículo científico publicado en 2017

Large-scale association analysis identifies new risk loci for coronary artery disease

artículo científico publicado en 2012

LocusZoom: regional visualization of genome-wide association scan results

artículo científico publicado en 2010

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

artículo científico publicado en 2014

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

artículo científico publicado en 2020

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

artículo científico publicado en 2010

Maternal - offspring HLA-DRB1 compatibility in multiple sclerosis

artículo científico publicado en 2005

Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

artículo científico publicado en 2020

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of gene-level tests for rare variant association

artículo científico publicado en 2013

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

artículo científico publicado en 2008

Microchimerism in autoimmunity and transplantation: potential relevance to multiple sclerosis

artículo científico publicado en 2002

Multiple sclerosis susceptibility and the X chromosome.

artículo científico publicado en 2007

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

artículo científico publicado en 2008

No large-effect low-frequency coding variation found for myocardial infarction

artículo científico publicado en 2014

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parent-of-origin effect in multiple sclerosis: observations in half-siblings

artículo científico publicado en 2004

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

artículo científico publicado en 2012

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

artículo científico publicado en 2016

Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease

artículo científico publicado en 2017

Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve

artículo científico publicado en 2017

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

artículo científico publicado en 2018

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

artículo científico publicado en 2018

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations

artículo científico publicado en 2007

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations

Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts

scientific article published on 18 May 2020

Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes

artículo científico publicado en 2007

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

artículo científico publicado en 2019

Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis

scientific article published on 23 April 2019

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

artículo científico publicado en 2009

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

artículo científico publicado en 2017

Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

artículo científico publicado en 2014

TCR beta polymorphisms and multiple sclerosis

artículo científico publicado en 2004

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The power of genetic diversity in genome-wide association studies of lipids

The power of meta-analysis in genome-wide association studies

artículo científico publicado en 2013

Timing of birth and risk of multiple sclerosis: population based study

artículo científico publicado en 2004

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Twin concordance and sibling recurrence rates in multiple sclerosis.

artículo científico publicado en 2003

Use of a Polygenic Risk Score Improves Prediction of Myocardial Injury after Non-cardiac Surgery

artículo científico publicado en 2020

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

artículo científico publicado en 2008

Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.

artículo científico publicado en 2014

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

artículo científico publicado en 2014

WikiGWA: an open platform for collecting and using genome-wide association results

artículo científico publicado en 2013

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