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Lista de obras de James F. Wilson

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Selection Operator for Summary Association Statistics Reveals Allelic Heterogeneity of Complex Traits

artículo científico publicado en 2017

A Y chromosome census of the British Isles

artículo científico publicado en 2003

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A combined long-range phasing and long haplotype imputation method to impute phase for SNP genotypes ⬇️

artículo científico publicado el 10 de marzo de 2011

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

artículo científico publicado en 2011

A general approach for haplotype phasing across the full spectrum of relatedness

artículo científico publicado en 2014

A genetic atlas of human admixture history

artículo científico

A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals

artículo científico publicado en 2017

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

artículo científico publicado en 2012

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project

artículo científico publicado en 2009

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

artículo científico publicado en 2011

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

artículo científico publicado en 2015

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level

artículo científico publicado en 2010

A new prevalence study of multiple sclerosis in Orkney, Shetland and Aberdeen city

artículo científico publicado en 2012

A predominantly indigenous paternal heritage for the Austronesian-speaking peoples of insular Southeast Asia and Oceania.

artículo científico publicado en 2001

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

artículo científico publicado en 2016

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

Abundant pleiotropy in human complex diseases and traits.

artículo científico publicado en 2011

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

artículo científico publicado en 2016

An actionable KCNH2 Long QT Syndrome variant detected by sequence and haplotype analysis in a population research cohort

scientific article published on 29 July 2019

An atlas of genetic scores to predict multi-omic traits

scientific article published on 29 March 2023

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

artículo científico publicado en 2013

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

artículo científico publicado en 2011

Association of Medication with the Human Plasma N-Glycome

artículo científico publicado en 2012

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

artículo científico publicado en 2013

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

artículo científico publicado en 2014

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of ‘Relative corticosterone deficiency’ with genetic variation in CYP17A1 and metabolic syndrome features

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

artículo científico

Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

artículo científico publicado en 2018

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Author Correction: The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland.

artículo científico publicado en 2018

Autoantibodies to osteoprotegerin are associated with increased bone resorption in rheumatoid arthritis

artículo científico publicado en 2015

Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study

artículo científico publicado en 2020

Bayesian association scan reveals loci associated with human lifespan and linked biomarkers

artículo científico publicado en 2017

Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome

artículo científico publicado en 2010

Biological, clinical and population relevance of 95 loci for blood lipids

artículo científico publicado en 2010

Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

artículo científico publicado en 2013

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates

artículo científico publicado en 2011

Chronotype and sleep duration: the influence of season of assessment

artículo científico publicado en 2014

Coffee Consumption and Kidney Function: A Mendelian Randomization Study

artículo científico publicado en 2019

Common variants associated with plasma triglycerides and risk for coronary artery disease

artículo científico publicado en 2013

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

artículo científico publicado en 2010

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Common variants in Mendelian kidney disease genes and their association with renal function

artículo científico publicado en 2013

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

scientific article published on 24 October 2008

Comparative assessment of methods for estimating individual genome-wide homozygosity-by-descent from human genomic data

artículo científico publicado en 2010

Comparison of participant information and informed consent forms of five European studies in genetic isolated populations

artículo científico publicado en 2010

Copy number variation across European populations

artículo científico publicado en 2011

Correction to: Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

artículo científico publicado en 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.

artículo científico publicado en 2018

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

scientific article published on 19 December 2013

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Determinants of retinal microvascular features and their relationships in two European populations.

artículo científico publicado en 2017

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

artículo científico publicado en 2012

Discovery and refinement of loci associated with lipid levels

artículo científico publicado en 2013

Disentangling the genetics of lean mass

article

Does inbreeding affect N-glycosylation of human plasma proteins?

artículo científico publicado en 2011

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

artículo científico publicado en 2019

Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

artículo científico

Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Estrogens regulate glycosylation of IgG in women and men

artículo científico publicado en 2017

Evaluation of bioelectrical impedance analysis for identifying overweight individuals at increased cardiometabolic risk: a cross-sectional study

artículo científico publicado en 2014

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

artículo científico publicado en 2017

Evidence of inbreeding depression on human height

artículo científico publicado en 2012

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

artículo científico publicado en 2017

Extensive female-mediated gene flow from sub-Saharan Africa into near eastern Arab populations

artículo científico publicado en 2003

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

Farming, Foreign Holidays, and Vitamin D in Orkney

artículo científico publicado en 2016

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

artículo científico publicado en 2015

Founding mothers of Jewish communities: geographically separated Jewish groups were independently founded by very few female ancestors

artículo científico publicado en 2002

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

artículo científico publicado en 2018

GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

artículo científico publicado en 2017

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

artículo científico publicado en 2013

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

article

Genes predict village of origin in rural Europe

artículo científico publicado en 2010

Genetic Correlations Between Diabetes and Glaucoma: An Analysis of Continuous and Dichotomous Phenotypes

artículo científico publicado en 2019

Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

artículo científico publicado en 2012

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of circulating lipid levels

artículo científico publicado en 2011

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic determinants of circulating sphingolipid concentrations in European populations

scientific article published on 02 October 2009

Genetic evidence of assortative mating in humans

article

Genetic insights into biological mechanisms governing human ovarian ageing

artículo científico publicado en 2021

Genetic mechanisms of critical illness in Covid-19

scientific article published on 11 December 2020

Genetic mechanisms of critical illness in Covid-19

artículo científico publicado en 2020

Genetic predictors of fibrin D-dimer levels in healthy adults

artículo científico publicado en 2011

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants in RBFOX3 are associated with sleep latency

artículo científico publicado en 2016

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

artículo científico publicado en 2011

Genetic variants linked to education predict longevity

artículo científico publicado en 2016

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

artículo científico publicado en 2011

Genetic variation within the Y chromosome is not associated with histological characteristics of the atherosclerotic carotid artery or aneurysmal wall

artículo científico publicado en 2017

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

artículo científico publicado en 2015

Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin

artículo científico publicado en 2014

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.

artículo científico publicado en 2016

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

artículo científico publicado en 2016

Genome-wide analysis of epistasis in body mass index using multiple human populations

artículo científico publicado en 2012

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

artículo científico publicado en 2014

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

artículo científico publicado en 2017

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

artículo científico publicado en 2013

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

artículo científico publicado en 2013

Genome-wide association analyses in >119,000 individuals identifies thirteen morningness and two sleep duration loci

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

artículo científico publicado en 2022

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

artículo científico publicado en 2019

Genome-wide association analysis identifies multiple loci related to resting heart rate

artículo científico publicado en 2010

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association and functional follow-up reveals new loci for kidney function

artículo científico publicado en 2012

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

artículo científico publicado en 2011

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

artículo científico publicado en 2018

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

artículo científico publicado en 2014

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

artículo científico publicado en 2014

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide association study identifies five loci associated with lung function

artículo científico publicado en 2010

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

artículo científico publicado en 2012

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

artículo científico publicado en 2011

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

artículo científico publicado en 2018

Genome-wide association uncovers shared genetic effects among personality traits and mood states

artículo científico publicado en 2012

Genome-wide associations for birth weight and correlations with adult disease

artículo científico publicado en 2016

Genome-wide homozygosity and multiple sclerosis in Orkney and Shetland Islanders

artículo científico publicado en 2011

Genome-wide linkage analysis of serum creatinine in three isolated European populations.

artículo científico publicado en 2009

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

artículo científico publicado en 2013

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

artículo científico publicado en 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

artículo científico publicado en 2012

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

artículo científico publicado en 2017

Genome-wide meta-analysis of common variant differences between men and women

artículo científico publicado en 2012

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci

artículo científico publicado en 2014

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

artículo científico publicado en 2017

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

artículo científico publicado en 2014

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

artículo científico publicado en 2014

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

artículo científico publicado en 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

artículo científico publicado en 2017

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

artículo científico publicado en 2020

Genomic insights into the origin of farming in the ancient Near East

artículo científico publicado en 2016

Genomic insights into the population structure and history of the Irish Travellers

artículo científico publicado en 2017

Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models

artículo científico publicado en 2015

Genomic runs of homozygosity record population history and consanguinity

artículo científico publicado en 2010

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation

artículo científico publicado en 2010

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

Global variability of the human IgG glycome ⬇️

artículo científico publicado en 2020

Glycans are a novel biomarker of chronological and biological ages

artículo científico publicado en 2013

Glycomics meets lipidomics—associations of N-glycans with classical lipids, glycerophospholipids, and sphingolipids in three European populations

artículo científico publicado en 2011

Glycosylation Alterations in Multiple Sclerosis Show Increased Proinflammatory Potential

artículo científico publicado en 2020

Glycosylation Profile of Immunoglobulin G Is Cross-Sectionally Associated With Cardiovascular Disease Risk Score and Subclinical Atherosclerosis in Two Independent Cohorts.

artículo científico publicado en 2018

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

artículo científico publicado en 2020

Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory

artículo científico publicado en 2014

High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations

artículo científico publicado en 2011

Homozygous loss-of-function variants in European cosmopolitan and isolate populations

artículo científico publicado en 2015

Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome

artículo científico publicado en 2013

Hundreds of variants clustered in genomic loci and biological pathways affect human height

artículo científico publicado en 2010

Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density

artículo científico publicado en 2017

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

artículo científico publicado en 2013

Identity-by-descent-based phasing and imputation in founder populations using graphical models

artículo científico publicado en 2011

IgG N-Glycosylation Galactose Incorporation Ratios for the Monitoring of Classical Galactosaemia

artículo científico publicado en 2015

IgG glycan patterns are associated with type 2 diabetes in independent European populations

artículo científico publicado en 2017

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

artículo científico publicado en 2017

Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies

artículo científico publicado en 2013

Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

artículo científico publicado en 2017

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions

scientific article published on 25 November 2019

Inference of identity by descent in population isolates and optimal sequencing studies

scientific article published on 30 January 2013

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

artículo científico publicado en 2012

Integrative pathway genomics of lung function and airflow obstruction

artículo científico publicado en 2015

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

artículo científico publicado en 2016

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

artículo científico publicado en 2017

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

artículo científico publicado en 2012

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

artículo científico publicado en 2015

Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits

artículo científico publicado en 2022

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

artículo científico publicado en 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

artículo científico publicado en 2012

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

artículo científico publicado en 2015

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

artículo científico publicado en 2018

Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene

artículo científico publicado en 2009

Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits

artículo científico publicado en 2020

Lipidomics, Atrial Conduction, and Body Mass Index

scientific article published on 15 July 2019

Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies

artículo científico publicado en 2013

Localising loci underlying complex trait variation using Regional Genomic Relationship Mapping

artículo científico publicado en 2012

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

artículo científico publicado en 2013

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

scientific article published in Nature Communications

Low-frequency variation inTP53has large effects on head circumference and intracranial volume

Mapping the serum proteome to neurological diseases using whole genome sequencing

artículo científico publicado en 2021

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

artículo científico publicado en 2019

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

artículo científico publicado en 2012

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

artículo científico publicado en 2010

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

artículo científico publicado en 2010

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

artículo científico publicado en 2009

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

artículo científico publicado en 2016

Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

artículo científico publicado en 2015

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

artículo científico publicado en 2015

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

artículo científico publicado en 2011

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

artículo científico publicado en 2013

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

artículo científico publicado en 2011

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

artículo científico publicado en 2013

Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels

artículo científico publicado en 2010

Modulation of genetic associations with serum urate levels by body-mass-index in humans

artículo científico publicado en 2015

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

artículo científico publicado en 2015

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

scientific article published on 21 May 2020

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

scientific article published on 27 November 2019

Multicohort analysis of the maternal age effect on recombination

artículo científico publicado en 2015

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

artículo científico publicado en 2013

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

artículo científico publicado en 2017

Multivariate genomic scan implicates novel loci and haem metabolism in human ageing

artículo científico publicado en 2020

Mutations in HNF1A result in marked alterations of plasma glycan profile

artículo científico publicado en 2012

Negative effect of vitamin D on kidney function: a Mendelian randomization study.

artículo científico publicado en 2018

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

scientific article published on 29 July 2019

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

artículo científico publicado en 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

artículo científico publicado en 2017

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

artículo científico publicado en 2012

New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.

artículo científico publicado en 2010

New loci associated with kidney function and chronic kidney disease

artículo científico publicado en 2010

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

artículo científico publicado en 2013

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

artículo científico publicado en 2014

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

artículo científico publicado en 2017

Novel Genetic Locus Influencing Retinal Venular Tortuosity Is Also Associated With Risk of Coronary Artery Disease

scientific article published on 10 October 2019

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

artículo científico publicado en 2010

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

artículo científico publicado en 2019

Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study

artículo científico publicado en 2012

Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults

Population genetic structure of variable drug response

artículo científico publicado en 2001

Population structure and genome-wide patterns of variation in Ireland and Britain

artículo científico publicado en 2010

Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16.

artículo científico publicado en 2005

Prevalence and clinical prediction of osteoporosis in a contemporary cohort of patients with rheumatoid arthritis

artículo científico publicado en 2014

Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies

artículo científico publicado en 2020

Proteome-by-phenome Mendelian Randomisation detects 38 proteins with causal roles in human diseases and traits

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

artículo científico publicado en 2019

Quantifying the increase in average human heterozygosity due to urbanisation

artículo científico publicado en 2008

Rare Deep-Rooting Y Chromosome Lineages in Humans: Lessons for Phylogeography ⬇️

artículo científico publicado el 1 de septiembre de 2003

Recent genomic heritage in Scotland

artículo científico publicado en 2015

Regional variation in the incidence rate and sex ratio of multiple sclerosis in Scotland 2010-2017: findings from the Scottish Multiple Sclerosis Register

scientific article published on 11 June 2019

Reply to 'Misestimation of heritability and prediction accuracy of male-pattern baldness'.

artículo científico publicado en 2018

Resolving the ancestry of Austronesian-speaking populations

artículo científico publicado en 2016

Runs of homozygosity do not influence survival to old age.

artículo científico publicado en 2011

Runs of homozygosity in European populations

artículo científico publicado en 2008

Runs of homozygosity: windows into population history and trait architecture.

artículo científico publicado en 2018

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

scientific journal article

Sequencing and analysis of an Irish human genome

artículo científico publicado en 2010

Sequencing of high-complexity DNA pools for identification of nucleotide and structural variants in regions associated with complex traits

artículo científico publicado en 2011

Serum metabolomic profiles associated with subclinical and clinical cardiovascular phenotypes in people with type 2 diabetes

artículo científico publicado en 2022

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

artículo científico publicado en 2013

Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene

artículo científico publicado en 2009

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

artículo científico publicado en 2015

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

artículo científico publicado en 2012

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

artículo científico publicado en 2018

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

artículo científico publicado en 2019

The Association Between Glycosylation of Immunoglobulin G and Hypertension: A Multiple Ethnic Cross-Sectional Study

scientific article published on April 2016

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland

artículo científico publicado en 2017

The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape

artículo científico publicado en 2015

The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape.

artículo científico publicado en 2015

The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis

artículo científico publicado en 2010

The association between galactosylation of immunoglobulin G and body mass index.

artículo científico publicado en 2013

The case for launch of an international DNA-based birth cohort study

artículo científico publicado en 2011

The genetic landscape of Scotland and the Isles

artículo científico publicado en 2019

The genetic structure of the world's first farmers

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269

artículo científico publicado en 2012

The power of genetic diversity in genome-wide association studies of lipids

The power of regional heritability analysis for rare and common variant detection: simulations and application to eye biometrical traits

artículo científico publicado en 2013

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

artículo científico publicado en 2010

Trends in disease incidence and survival and their effect on mortality in Scotland: nationwide cohort study of linked hospital admission and death records 2001-2016

scientific article published on 25 March 2020

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

artículo científico publicado en 2010

Uncovering networks from genome-wide association studies via circular genomic permutation

artículo científico publicado en 2012

Variants associated with expression have sex-differential effects on lung function

artículo científico publicado en 2020

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

artículo científico publicado en 2010

Variants in STAT5B Associate with Serum TC and LDL-C Levels

article published in 2011

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

artículo científico publicado en 2016

Weighted functional linear regression models for gene-based association analysis.

artículo científico publicado en 2018

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