Lista de obras - Michiel Vermeulen - Dominio Público Uruguay

A CDK-mediated phosphorylation switch of disordered protein condensation

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

artículo científico publicado en 2021

A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein

artículo científico publicado en 2011

A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. ⬇️

artículo científico publicado en 2017

A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth

scientific journal article

A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation

artículo científico publicado en 2013

A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin

artículo científico

A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics.

artículo científico publicado en 2012

A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels

artículo científico publicado en 2013

Active DNA demethylation at enhancers during the vertebrate phylotypic period

artículo científico publicado en 2016

An Interaction Landscape of Ubiquitin Signaling

artículo científico publicado en 2017

An in vitro assay to study the recruitment and substrate specificity of chromatin modifying enzymes

artículo científico publicado en 2004

An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations

artículo científico publicado en 2015

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event

artículo científico publicado en 2015

Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder

artículo científico publicado en 2021

Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation

artículo científico publicado en 2007

BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

artículo científico publicado en 2019

CBFB-MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia.

artículo científico publicado en 2013

CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1

article

CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.

artículo científico publicado en 2010

Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.

artículo científico publicado en 2013

Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiae

artículo científico publicado en 2005

Characterizing Protein-Protein Interactions Using Mass Spectrometry: Challenges and Opportunities

artículo científico publicado en 2016

Chromosomal instability by mutations in the novel minor spliceosome component CENATAC

artículo científico publicado en 2021

Click-MS: Tagless Protein Enrichment Using Bioorthogonal Chemistry for Quantitative Proteomics

artículo científico publicado en 2016

DNA methylation: old dog, new tricks?

scientific article published on 01 November 2014

Developmental biology. A Me6Age for pluripotency

artículo científico publicado en 2015

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives

artículo científico publicado en 2013

EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer

artículo científico publicado en 2019

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells

scientific article published on 26 August 2019

Epigenetics and the prognosis of hepatocellular carcinoma

artículo científico publicado en 2012

Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling

artículo científico publicado en 2015

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 ⬇️

artículo científico publicado en 2017

Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs.

artículo científico publicado en 2014

Global profiling of protein-DNA and protein-nucleosome binding affinities using quantitative mass spectrometry.

artículo científico publicado en 2018

Grasping trimethylation of histone H3 at lysine 4.

artículo científico publicado en 2010

High confidence determination of specific protein-protein interactions using quantitative mass spectrometry

artículo científico publicado en 2008

High-throughput identification of human SNPs affecting regulatory element activity

scientific article published on 28 June 2019

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression.

artículo científico publicado en 2014

Histone propionylation is a mark of active chromatin

artículo científico publicado en 2017

Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader

artículo científico publicado en 2021

Identifying Chromatin Readers Using a SILAC-Based Histone Peptide Pull-Down Approach

Identifying Readers for (hydroxy)methylated DNA Using Quantitative Interaction Proteomics: Advances and Challenges Ahead

artículo científico publicado en 2019

Identifying nuclear protein-protein interactions using GFP affinity purification and SILAC-based quantitative mass spectrometry

artículo científico publicado en 2014

Identifying specific protein-DNA interactions using SILAC-based quantitative proteomics.

artículo científico publicado en 2013

Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells.

artículo científico publicado en 2018

In need of good neighbours: transcription factors require local DNA hypomethylation for target binding

artículo científico publicado en 2016

In vitro targeting reveals intrinsic histone tail specificity of the Sin3/histone deacetylase and N-CoR/SMRT corepressor complexes

artículo científico publicado en 2004

In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions

artículo científico publicado en 2014

Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response

artículo científico publicado en 2014

Induction and suppression of NF-κB signalling by a DNA virus of

scientific article published on 17 January 2019

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX

artículo científico publicado en 2014

Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction

artículo científico publicado en 2022

Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency

scientific article published on 21 November 2018

Integrative multi-omics analysis of intestinal organoid differentiation.

artículo científico publicado en 2018

Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

artículo científico publicado en 2008

Locus-specific chromatin isolation

scientific article published on 29 January 2020

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

artículo científico publicado en 2006

MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain

artículo científico publicado en 2014

MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding

artículo científico publicado en 2018

Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

scientific article published on 30 September 2019

Making the most of methylation

artículo científico publicado en 2013

Mass Spectrometry-Based Absolute Quantification of Single Xenopus Embryo Proteomes

Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma

artículo científico publicado en 2020

MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation

artículo científico publicado en 2012

Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements

artículo científico publicado en 2019

Molecular characterization of Sin3 PAH-domain interactor specificity and identification of PAH partners

artículo científico publicado en 2006

Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets

scientific article published on 17 January 2019

Multivalent engagement of TFIID to nucleosomes

artículo científico publicado en 2013

Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD

scientific journal article

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis.

artículo científico publicado en 2017

NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells

scientific article published in Nature Communications

Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila

artículo científico publicado en 2006

Nucleosome-interacting proteins regulated by DNA and histone methylation

artículo científico publicado en 2010

Off-the-shelf proximity biotinylation for interaction proteomics

artículo científico publicado en 2021

PAQMAN: Protein-nucleic acid affinity quantification by MAss spectrometry in nuclear extracts

scientific article published on 16 December 2019

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

artículo científico publicado en 2019

Perspective on unraveling the versatility of 'co-repressor' complexes.

artículo científico

Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis

artículo científico publicado en 2017

Phosphorylation of histone H3 Thr-45 is linked to apoptosis

artículo científico publicado en 2009

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

artículo científico publicado en 2019

Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding

artículo científico publicado en 2012

Proteome-wide identification of ubiquitin interactions using UbIA-MS.

artículo científico publicado en 2018

Proteomic landscape of the primary somatosensory cortex upon sensory deprivation.

artículo científico publicado en 2017

Publisher Correction: Locus-specific chromatin isolation

artículo científico publicado en 2020

Purification and enrichment of specific chromatin loci

scientific article published on 09 March 2020

Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation

scientific article published on 17 October 2019

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes

artículo científico publicado en 2013

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers

artículo científico publicado en 2010

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

artículo científico publicado en 2010

Quantitative proteomics for epigenetics.

artículo científico publicado en 2010

Quantitative proteomics: a tool to assess cell differentiation

artículo científico publicado en 2009

RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer

artículo científico publicado en 2020

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131

artículo científico publicado en 2016

Redox-dependent control of FOXO/DAF-16 by transportin-1.

artículo científico publicado en 2013

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage

artículo científico publicado en 2010

Research Highlights: Highlights from the latest articles on epigenetics in tumorigenesis

Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer

artículo científico publicado en 2021

SDHD Promoter Mutations Ablate GABP Transcription Factor Binding in Melanoma.

artículo científico publicado en 2017

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

artículo científico publicado en 2014

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

artículo científico publicado en 2021

Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex

artículo científico publicado en 2016

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

artículo científico publicado en 2007

Single-Cell DNA Methylation Profiling: Technologies and Biological Applications

artículo científico publicado en 2018

Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay

scientific article published on 30 May 2019

Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

artículo científico publicado en 2018

Splicing and Chromatin Factors Jointly Regulate Epidermal Differentiation

artículo científico publicado en 2018

Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics

artículo científico publicado en 2012

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.

artículo científico publicado en 2018

Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma

article

Targeted discovery tools: proteomics and chromatin immunoprecipitation-on-chip

artículo científico publicado en 2005

Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.

artículo científico publicado en 2014

The Complexity of PRC2 Subcomplexes

artículo científico publicado en 2019

The HDAC inhibitor SAHA regulates CBX2 stability via a SUMO-triggered ubiquitin-mediated pathway in leukemia.

artículo científico publicado en 2018

The Mad1-Sin3B interaction involves a novel helical fold

artículo científico publicado en 2000

The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules

artículo científico publicado en 2016

The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment

scientific article published on 29 April 2019

The Pluripotency Regulator PRDM14 Requires Hematopoietic Regulator CBFA2T3 to Initiate Leukemia in Mice

scientific article published on 23 April 2019

The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes

scientific article published on 01 March 2019

The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

scientific journal article

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation

artículo científico publicado en 2016

The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA

artículo científico publicado en 2020

The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy

scientific article published on 28 October 2019

The interactome of a family of potential methyltransferases in HeLa cells

artículo científico publicado en 2019

Towards cracking the epigenetic code using a combination of high-throughput epigenomics and quantitative mass spectrometry-based proteomics

artículo científico publicado en 2011

Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics

artículo científico publicado en 2015

Two chromatin remodeling activities cooperate during activation of hormone responsive promoters

artículo científico publicado en 2009

ZBTB2 reads unmethylated CpG island promoters and regulates embryonic stem cell differentiation

artículo científico publicado en 2018

ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage.

artículo científico publicado en 2016

Lista de obras de Michiel Vermeulen

A CDK-mediated phosphorylation switch of disordered protein condensation

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

A SILAC-based screen for Methyl-CpG binding proteins identifies RBP-J as a DNA methylation and sequence-specific binding protein

A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. ⬇️

A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth

A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation

A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin

A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics.

A novel microscopy-based high-throughput screening method to identify proteins that regulate global histone modification levels

Active DNA demethylation at enhancers during the vertebrate phylotypic period

An Interaction Landscape of Ubiquitin Signaling

An in vitro assay to study the recruitment and substrate specificity of chromatin modifying enzymes

An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event

Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder

Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation

BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

CBFB-MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia.

CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1

CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.

Cdyl, a new partner of the inactive X chromosome and potential reader of H3K27me3 and H3K9me2.

Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiae

Characterizing Protein-Protein Interactions Using Mass Spectrometry: Challenges and Opportunities

Chromosomal instability by mutations in the novel minor spliceosome component CENATAC

Click-MS: Tagless Protein Enrichment Using Bioorthogonal Chemistry for Quantitative Proteomics

DNA methylation: old dog, new tricks?

Developmental biology. A Me6Age for pluripotency

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives

EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer

EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells

Epigenetics and the prognosis of hepatocellular carcinoma

Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148 ⬇️

Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs.

Global profiling of protein-DNA and protein-nucleosome binding affinities using quantitative mass spectrometry.

Grasping trimethylation of histone H3 at lysine 4.

High confidence determination of specific protein-protein interactions using quantitative mass spectrometry

High-throughput identification of human SNPs affecting regulatory element activity

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression.

Histone propionylation is a mark of active chromatin

Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader

Identifying Chromatin Readers Using a SILAC-Based Histone Peptide Pull-Down Approach

Identifying Readers for (hydroxy)methylated DNA Using Quantitative Interaction Proteomics: Advances and Challenges Ahead

Identifying nuclear protein-protein interactions using GFP affinity purification and SILAC-based quantitative mass spectrometry

Identifying specific protein-DNA interactions using SILAC-based quantitative proteomics.

Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells.

In need of good neighbours: transcription factors require local DNA hypomethylation for target binding

In vitro targeting reveals intrinsic histone tail specificity of the Sin3/histone deacetylase and N-CoR/SMRT corepressor complexes

In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions

Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response

Induction and suppression of NF-κB signalling by a DNA virus of

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX

Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction

Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency

Integrative multi-omics analysis of intestinal organoid differentiation.

Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

Locus-specific chromatin isolation

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain

MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding

Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

Making the most of methylation

Mass Spectrometry-Based Absolute Quantification of Single Xenopus Embryo Proteomes

Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma

MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation

Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements

Molecular characterization of Sin3 PAH-domain interactor specificity and identification of PAH partners

Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets

Multivalent engagement of TFIID to nucleosomes

Myeloid transforming protein Evi1 interacts with methyl-CpG binding domain protein 3 and inhibits in vitro histone deacetylation by Mbd3/Mi-2/NuRD

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis.

NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells

Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila

Nucleosome-interacting proteins regulated by DNA and histone methylation

Off-the-shelf proximity biotinylation for interaction proteomics

PAQMAN: Protein-nucleic acid affinity quantification by MAss spectrometry in nuclear extracts

PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation

Perspective on unraveling the versatility of 'co-repressor' complexes.

Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis