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Lista de obras de Jürgen Burhenne

A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA.

artículo científico publicado en 2011

A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions.

artículo científico publicado en 2013

Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas

artículo científico publicado en 2011

Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy

artículo científico publicado en 2006

An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids

artículo científico publicado en 2020

Analysis of methylene blue in human urine by capillary electrophoresis

artículo científico publicado en 2005

Aprepitant, granisetron, and dexamethasone for prevention of chemotherapy-induced nausea and vomiting after high-dose melphalan in autologous transplantation for multiple myeloma: results of a randomized, placebo-controlled phase III trial

artículo científico publicado en 2014

Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics

artículo científico publicado en 2004

Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent.

artículo científico publicado en 2009

CYP2C19 genotype is a major factor contributing to the highly variable pharmacokinetics of voriconazole

artículo científico publicado en 2008

CYP2C9 polymorphism is not a major determinant of bosentan exposure in healthy volunteers.

artículo científico publicado en 2013

CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores

scientific article published on January 2014

CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir

artículo científico publicado en 2007

Cation exchange resins as pharmaceutical carriers for methylene blue: binding and release

artículo científico publicado en 2007

Cellular pharmacokinetic/pharmacodynamic relationship of platinum cytostatics in head and neck squamous cell carcinoma evaluated by liquid chromatography coupled to tandem mass spectrometry

artículo científico publicado en 2011

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters

artículo científico publicado en 2014

Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers

artículo científico publicado en 2014

Clinical feasibility of dried blood spots: Analytics, validation, and applications.

artículo científico publicado en 2016

Comparative Bioavailability of the Microemulsion Formulation of Cyclosporine (Neoral) With a Generic Dispersion Formulation (Cicloral) in Young Healthy Male Volunteers

scientific article published on 01 June 2006

Concentration effect relationship of CYP3A inhibition by ritonavir in humans.

artículo científico publicado en 2013

Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction

artículo científico publicado en 2003

Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m).

artículo científico publicado en 2005

Daily honey consumption does not change CYP3A activity in humans

artículo científico publicado en 2010

Detection of RNA modifications.

artículo científico publicado en 2010

Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using A limited sampling strategy

artículo científico publicado en 2011

Development of capillary electrophoresis methods for the analysis of fluoroquinolones and application to the study of the influence of humic substances on their photodegradation in aqueous phase

article

Disease-associated QT-shortage versus quinine associated QT-prolongation: age dependent ECG-effects in Ghanaian children with severe malaria

artículo científico publicado en 2014

Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

artículo científico publicado en 2002

Dried Blood Spot Technique for the Monitoring of Ambrisentan, Bosentan, Sildenafil, and Tadalafil in Patients with Pulmonary Arterial Hypertension

artículo científico publicado en 2015

Dried-Blood-Spot Technique to Monitor Direct Oral Anticoagulants: Clinical Validation of a UPLC-MS/MS-Based Assay

artículo científico publicado en 2018

Drug interaction of efavirenz and midazolam: efavirenz activates the CYP3A-mediated midazolam 1'-hydroxylation in vitro

artículo científico publicado en 2012

Efavirenz treatment and false-positive results in benzodiazepine screening tests.

artículo científico publicado en 2009

Effect of Rifampicin and CYP2B6 Genotype on Long-Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

article

Effect of simultaneous induction and inhibition of CYP3A by St John's Wort and ritonavir on CYP3A activity

artículo científico publicado en 2009

Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity

artículo científico publicado en 2012

Efficacy of methylene blue monotherapy in semi-immune adults with uncomplicated falciparum malaria: a controlled trial in Burkina Faso

artículo científico publicado en 2010

Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma

artículo científico publicado en 2007

Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling

artículo científico publicado en 2010

Fetal calf sera can distort cell-based luminescent proteasome assays through heat-resistant chymotrypsin-like activity

artículo científico publicado en 2014

Fluvoxamine affects sildenafil kinetics and dynamics

artículo científico publicado en 2005

HRGC-ECD and HRGC-NICI SIM quantification of toxaphene residues in selected marine organism by environmentally relevant chlorobornanes as standard

article by Li Xu et al published January 1994 in Chemosphere

High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome.

artículo científico publicado en 2018

High absolute bioavailability of methylene blue given as an aqueous oral formulation

artículo científico publicado en 2008

High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

article

Highly sensitive determination of saquinavir in biological samples using liquid chromatography-tandem mass spectrometry

artículo científico publicado en 2003

In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins

artículo científico publicado en 2005

Induction of voriconazole metabolism by rifampin in a patient with acute myeloid leukemia: importance of interdisciplinary communication to prevent treatment errors with complex medications.

artículo científico publicado en 2007

Influence of St. Johnâ s wort on the steadystate pharmacokinetics and metabolism of bosentan

artículo científico publicado en 2014

Influence of lipid lowering fibrates on P-glycoprotein activity in vitro.

artículo científico publicado en 2004

Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells

artículo científico publicado en 2012

Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.

artículo científico publicado en 2013

Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients

artículo científico publicado en 2017

Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? The HIV-TB pharmagene study

artículo científico publicado en 2015

Isolation and characterization of environmental relevant single toxaphene components

Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults

artículo científico publicado en 2014

Liposomal sphingomyelin influences the cellular lipid profile of human lymphoblastic leukemia cells without effect on P-glycoprotein activity.

artículo científico publicado en 2013

Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania

artículo científico publicado en 2012

Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients

artículo científico publicado en 2016

Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients

artículo científico publicado en 2010

Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

artículo científico publicado en 2011

Marked differences in the prevalence of chloroquine resistance between urban and rural communities in Burkina Faso

artículo científico publicado en 2007

Methylene blue for malaria in Africa: results from a dose-finding study in combination with chloroquine

artículo científico publicado en 2006

Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans

artículo científico publicado en 2015

Modulators of very low voriconazole concentrations in routine therapeutic drug monitoring.

artículo científico publicado en 2011

Monitoring of lopinavir and ritonavir in peripheral blood mononuclear cells, plasma, and ultrafiltrate using a selective and highly sensitive LC/MS/MS assay

artículo científico

No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment.

artículo científico publicado en 2010

Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics

artículo científico publicado en 2005

Oral contraception does not alter single dose saquinavir pharmacokinetics in women

artículo científico publicado en 2004

Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients

artículo científico publicado en 2011

Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients

artículo científico publicado en 2012

Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40.

artículo científico publicado en 2003

Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment

artículo científico publicado en 2014

Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria

artículo científico publicado en 2004

Pharmacokinetics of sulfobutylether-beta-cyclodextrin and voriconazole in patients with end-stage renal failure during treatment with two hemodialysis systems and hemodiafiltration

artículo científico publicado en 2010

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype

artículo científico publicado en 2009

Pharmacokinetics, tissue concentrations, and safety of the antifungal agent voriconazole in chickens

artículo científico publicado en 2008

Polar photodegradation products of quinolones determined by HPLC/MS/MS

article published in 1999

Poor solubility limiting significance of in-vitro studies with HIV protease inhibitors

artículo científico publicado en 2002

Potent cytochrome P450 2C19 genotype–related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir

scientific article published on 03 July 2006

Pre-systemic Elimination of Tilidine: Localization and Consequences for the Formation of the Active Metabolite Nortilidine

Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study

artículo científico publicado en 2016

Prolonged-Release Tacrolimus Is Less Susceptible to Interaction With the Strong CYP3A Inhibitor Voriconazole in Healthy Volunteers

scientific article published on 10 July 2019

Quantification of cationic anti-malaria agent methylene blue in different human biological matrices using cation exchange chromatography coupled to tandem mass spectrometry

artículo científico publicado en 2008

Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry.

artículo científico publicado en 2012

Quantification of microdosed oral yohimbine and its major metabolite in human plasma in the picogram range

scientific article published on 14 August 2019

Quantification of retinoid concentrations in human serum and brain tumor tissues

artículo científico publicado en 2012

Quantification of vorinostat and its main metabolites in plasma and intracellular vorinostat in PBMCs by liquid chromatography coupled to tandem mass spectrometry and its relation to histone deacetylase activity in human blood

article published in 2014

Rapid and Sensitive Drug Quantification in Tissue Sections Using Matrix Assisted Laser Desorption Ionization-Ion Mobility-Mass Spectrometry Profiling

scientific article published on 23 January 2020

Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI-IM-MS/MS Assay

artículo científico publicado en 2020

Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity

artículo científico publicado en 2013

Reduction of saquinavir exposure by coadministration of loperamide: a two-way pharmacokinetic interaction

artículo científico publicado en 2004

Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma

artículo científico publicado en 2015

Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement

artículo científico publicado en 2001

Rivaroxaban and macitentan can be co-administered without dose adjustment but the combination of rivaroxaban and St. John´s Wort should be avoided

artículo científico publicado en 2018

Safety of the combination of chloroquine and methylene blue in healthy adult men with G6PD deficiency from rural Burkina Faso

artículo científico publicado en 2005

Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841]

artículo científico publicado en 2005

Safety of voriconazole in a patient with CYP2C9*2/CYP2C9*2 genotype.

artículo científico publicado en 2006

Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure

artículo científico publicado en 2011

Simultaneous determination of hypericin and hyperforin in human plasma with liquid chromatography-tandem mass spectrometry

artículo científico publicado en 2004

Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

Steady-state pharmacokinetics and metabolism of voriconazole in patients.

artículo científico publicado en 2013

Structure elucidation of the three most important toxaphene congeners by X-ray analysis

Structure of the toxaphene compound 2,5-endo,6-exo,8,9,9,10,10-octachlorobornene-2: a temperature-dependent formation of two rotamers

artículo científico publicado en 2005

Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers

artículo científico publicado en 2004

Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease: two case reports

artículo científico publicado en 2014

Successful treatment with voriconazole of Aspergillus brain abscess in a boy with medulloblastoma

artículo científico publicado en 2007

Sulphobutylether-beta-cyclodextrin accumulation in critically ill patients with acute kidney injury treated with intravenous voriconazole under extended daily dialysis

artículo científico publicado en 2010

Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity

artículo científico publicado en 2014

The NK₁ receptor antagonist aprepitant does not alter the pharmacokinetics of high-dose melphalan chemotherapy in patients with multiple myeloma.

artículo científico publicado en 2010

The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers - An in vitro and in vivo comparison.

artículo científico publicado en 2016

The effect of induction of CYP3A4 by St John's wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype

artículo científico publicado en 2014

The role of biotic and abiotic degradation processes during the formation of typical toxaphene peak patterns in aquatic biota

scientific article published on 01 August 1999

Theoretical consideration of the structural variety in the toxaphene mixture taking into account recent experimental results

Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters

artículo científico publicado en 2013

Turquoise to dark green organs at autopsy

artículo científico publicado en 2009

Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry after chlorzoxazone microdosing.

artículo científico publicado en 2016

Undeclared exposure to St. John's Wort in hospitalized patients

artículo científico publicado en 2004

Voriconazole brain tissue levels in rhinocerebral aspergillosis in a successfully treated young woman

artículo científico publicado en 2006

Voriconazole concentration in human aqueous humor and plasma during topical or combined topical and systemic administration for fungal keratitis

artículo científico publicado en 2006