Lista de obras - Moosa Mohammadi - Dominio Público Uruguay

A Conserved Allosteric Pathway in Tyrosine Kinase Regulation

scientific article published on 13 June 2019

A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23

artículo científico publicado en 2019

A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

artículo científico publicado en 2007

A crystallographic snapshot of tyrosine trans-phosphorylation in action

artículo científico publicado en 2008

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis

artículo científico publicado en 2007

A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration

artículo científico publicado en 2017

A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

artículo científico publicado en 2005

A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1

artículo científico publicado en 2005

A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination.

artículo científico publicado en 2018

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1 ⬇️

artículo científico publicado el 1 de octubre de 1991

Aggregation-induced activation of the epidermal growth factor receptor protein tyrosine kinase

artículo científico publicado en 1993

Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization

artículo científico publicado en 2005

Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23

artículo científico publicado en 2005

Arterial klotho expression and FGF23 effects on vascular calcification and function

artículo científico publicado en 2013

Autoregulatory mechanisms in protein-tyrosine kinases

artículo científico publicado en 1998

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

artículo científico publicado en 2007

Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities

artículo científico publicado en 2004

Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding.

artículo científico publicado en 2014

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases ⬇️

artículo científico publicado el 5 de abril de 1991

Compositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexes

artículo científico publicado en 2009

Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations.

artículo científico publicado en 2014

Conversion of a paracrine fibroblast growth factor into an endocrine fibroblast growth factor

artículo científico publicado en 2012

Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations

artículo científico publicado en 2013

Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels

artículo científico publicado en 2009

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

artículo científico publicado en 1998

Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition

artículo científico publicado en 2001

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

artículo científico publicado en 2000

Curtailing FGF19's mitogenicity by suppressing its receptor dimerization ability

artículo científico publicado en 2020

DFG-out mode of inhibition by an irreversible type-1 inhibitor capable of overcoming gate-keeper mutations in FGF receptors

artículo científico publicado en 2014

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

artículo científico publicado en 2008

Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors

artículo científico publicado en 2014

Different tyrosine autophosphorylation requirements in fibroblast growth factor receptor-1 mediate urokinase-type plasminogen activator induction and mitogenesis

artículo científico

Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis

artículo científico publicado en 2009

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

artículo científico publicado en 2007

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

artículo científico publicado en 2017

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

artículo científico publicado en 2007

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

artículo científico publicado en 2014

Erratum: Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

artículo científico publicado en 2015

Exploring mechanisms of FGF signalling through the lens of structural biology ⬇️

artículo científico publicado el 13 de febrero de 2013

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis

artículo científico publicado en 2008

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

artículo científico publicado en 2009

FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice

artículo científico publicado en 2015

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway

artículo científico publicado en 2012

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

artículo científico publicado en 2009

FGF23 promotes renal calcium reabsorption through the TRPV5 channel

scientific journal article

FGF23 regulates renal sodium handling and blood pressure

article by O. Andrukhova et al published December 2012 in Bone

FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.

artículo científico publicado en 2013

Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism

artículo científico publicado en 2018

Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs

artículo científico publicado en 2003

Fibroblast growth factor 1 ameliorates diabetic nephropathy by an anti-inflammatory mechanism

artículo científico publicado en 2017

Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury

artículo científico publicado en 2016

Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ.

artículo científico publicado en 2012

Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: EFFECTS ON EMBRYO SURVIVAL.

artículo científico publicado en 2016

Frequency of Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism.

artículo científico publicado en 2009

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

artículo científico publicado en 2007

Generation of recombinant cytoplasmic domain of epidermal growth factor receptor with intrinsic protein tyrosine kinase activity

artículo científico publicado en 1990

Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia

artículo científico publicado en 2012

Genetic testing facilitates prepubertal diagnosis of congenital hypogonadotropic hypogonadism.

artículo científico publicado en 2017

Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels

artículo científico publicado en 2009

Grb2, a double-edged sword of receptor tyrosine kinase signaling

artículo científico publicado en 2012

Hedgehogs like it sweet, too.

artículo científico publicado en 2006

Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix

artículo científico publicado en 2009

Identification of phosphopeptides by MALDI Q-TOF MS in positive and negative ion modes after methyl esterification

artículo científico publicado en 2005

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

artículo científico publicado en 1996

Impaired FGF signaling contributes to cleft lip and palate

artículo científico publicado en 2007

Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism ⬇️

scientific article published on 09 October 2009

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

artículo científico publicado en 2008

Induction of urokinase-type plasminogen activator by fibroblast growth factor (FGF)-2 is dependent on expression of FGF receptors and does not require activation of phospholipase Cgamma1

artículo científico publicado en 1996

Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.

artículo científico

Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia

artículo científico publicado en 2018

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.

artículo científico publicado en 2008

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

artículo científico publicado en 2004

Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.

artículo científico

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

artículo científico publicado en 2009

KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism

artículo científico publicado en 2017

Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly

artículo científico publicado en 2004

Klotho coreceptors inhibit signaling by paracrine fibroblast growth factor 8 subfamily ligands

artículo científico publicado en 2012

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma

artículo científico publicado en 2009

Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation

scientific article published on 20 January 2020

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

artículo científico publicado en 2007

Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology

artículo científico publicado en 2013

Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

artículo científico publicado en 2013

Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes

artículo científico publicado en 2006

Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

artículo científico publicado en 2006

Nonsense mutations in FGF8 gene causing different degrees of human gonadotropin-releasing deficiency.

artículo científico publicado en 2010

Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases

scientific article published on 17 October 2019

Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion

artículo científico publicado en 2013

Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1

artículo científico publicado en 2012

Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis

artículo científico publicado en 1992

Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells

artículo científico publicado en 1994

Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice

artículo científico publicado en 2011

Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity

artículo científico publicado en 2003

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

artículo científico publicado en 2006

Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis

artículo científico publicado en 1995

Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

artículo científico publicado en 2017

Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4

scientific journal article

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

artículo científico publicado en 2010

Role of SH2-containing proteins in cellular signaling by receptor tyrosine kinases

artículo científico publicado el 1 de enero de 1992

SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma

artículo científico publicado en 1992

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

artículo científico publicado en 2000

Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes

artículo científico publicado en 1995

Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous beta-catenin

artículo científico publicado en 2008

Structural Biology of the FGF7 Subfamily

scientific article published on 12 February 2019

Structural Mimicry of A-Loop Tyrosine Phosphorylation by a Pathogenic FGF Receptor 3 Mutation

artículo científico publicado en 2013

Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

artículo científico publicado en 2003

Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain

artículo científico publicado en 2005

Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome

artículo científico publicado en 2001

Structural basis for fibroblast growth factor receptor activation

artículo científico publicado en 2005

Structure-based mutational analyses in FGF7 identify new residues involved in specific interaction with FGFR2IIIb

artículo científico publicado en 2003

The FGF family: biology, pathophysiology and therapy

artículo científico publicado en 2009

The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition

artículo científico publicado en 2012

The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody

artículo científico publicado en 2014

The parathyroid is a target organ for FGF23 in rats

scientific journal article

The structural biology of the FGF19 subfamily

artículo científico publicado en 2012

Therapeutic Effects of FGF23 c-tail Fc in a Murine Preclinical Model of X-Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption

artículo científico publicado en 2017

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

artículo científico publicado en 2007

Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ

artículo científico publicado en 2015

Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase Cγ

scholarly article by Zhifeng Huang published in January 2016

Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex

artículo científico publicado en 2014

Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability

artículo científico publicado en 2017

Understanding the molecular basis of Apert syndrome

artículo científico publicado en 2005

Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies

artículo científico publicado en 2012

α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling

artículo científico publicado en 2018

β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.

artículo científico publicado en 2017

Lista de obras de Moosa Mohammadi

A Conserved Allosteric Pathway in Tyrosine Kinase Regulation

A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23

A Molecular Brake in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

A crystallographic snapshot of tyrosine trans-phosphorylation in action

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis

A novel fibroblast growth factor-1 ligand with reduced heparin binding protects the heart against ischemia-reperfusion injury in the presence of heparin co-administration

A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1

A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination.

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1 ⬇️

Aggregation-induced activation of the epidermal growth factor receptor protein tyrosine kinase

Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization

Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23

Arterial klotho expression and FGF23 effects on vascular calcification and function

Autoregulatory mechanisms in protein-tyrosine kinases

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities

Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding.

Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases ⬇️

Compositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexes

Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations.

Conversion of a paracrine fibroblast growth factor into an endocrine fibroblast growth factor

Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations

Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

Curtailing FGF19's mitogenicity by suppressing its receptor dimerization ability

DFG-out mode of inhibition by an irreversible type-1 inhibitor capable of overcoming gate-keeper mutations in FGF receptors

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice

Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors

Different tyrosine autophosphorylation requirements in fibroblast growth factor receptor-1 mediate urokinase-type plasminogen activator induction and mitogenesis

Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

Erratum: Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

Exploring mechanisms of FGF signalling through the lens of structural biology ⬇️

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

FGF23 promotes renal calcium reabsorption through the TRPV5 channel

FGF23 regulates renal sodium handling and blood pressure

FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.

Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism

Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs

Fibroblast growth factor 1 ameliorates diabetic nephropathy by an anti-inflammatory mechanism

Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury

Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ.

Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: EFFECTS ON EMBRYO SURVIVAL.

Frequency of Impaired Fibroblast Growth Factor Receptor 1 Signaling as a Cause of Normosmic Idiopathic Hypogonadotropic Hypogonadism.

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

Generation of recombinant cytoplasmic domain of epidermal growth factor receptor with intrinsic protein tyrosine kinase activity

Genetic overlap in Kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia

Genetic testing facilitates prepubertal diagnosis of congenital hypogonadotropic hypogonadism.

Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels

Grb2, a double-edged sword of receptor tyrosine kinase signaling

Hedgehogs like it sweet, too.

Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix

Identification of phosphopeptides by MALDI Q-TOF MS in positive and negative ion modes after methyl esterification

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

Impaired FGF signaling contributes to cleft lip and palate

Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism ⬇️

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

Induction of urokinase-type plasminogen activator by fibroblast growth factor (FGF)-2 is dependent on expression of FGF receptors and does not require activation of phospholipase Cgamma1

Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.

Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism

Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly

Klotho coreceptors inhibit signaling by paracrine fibroblast growth factor 8 subfamily ligands

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma