Lista de obras - Mark D Hulett - Dominio Público Uruguay

A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4

scientific article published on 16 July 2019

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

artículo científico publicado en 2015

Access to the Parent Tetrakis(pyridine)gold(III) Trication, Facile Formation of Rare Au(III) Terminal Hydroxides, and Preliminary Studies of Biological Properties

artículo científico publicado en 2016

Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death

artículo científico publicado en 2019

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization

artículo científico publicado en 2016

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer

artículo científico publicado en 2008

Cell surface expression of a peptide encoded by the unrearranged TCR-Vbeta8.2 gene.

artículo científico publicado en 2005

Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation

artículo científico publicado en 2007

Characterization of FcR Ig-binding sites and epitope mapping

artículo científico

Chimeric Fc receptors identify functional domains of the murine high affinity receptor for IgG.

artículo científico publicado en 1991

Chimeric Fc receptors identify immunoglobulin-binding regions in human Fc gamma RII and Fc epsilon RI.

artículo científico publicado en 1993

Cloning and characterization of a mouse homologue of the human haematopoietic cell-specific four-transmembrane gene HTm4

scientific journal article

Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5'-flanking sequences

artículo científico publicado en 1995

Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.

artículo científico publicado en 1996

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

artículo científico publicado en 1999

Combating Human Pathogens and Cancer by Targeting Phosphoinositides and Their Metabolism

artículo científico publicado en 2019

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

artículo científico publicado en 2013

Convergent evolution of defensin sequence, structure and function ⬇️

artículo científico publicado en 2016

Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa

artículo científico publicado en 1999

Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1.

artículo científico publicado en 2011

Defining the morphologic features and products of cell disassembly during apoptosis.

artículo científico publicado en 2017

Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis

scientific article published on 01 December 2019

Determining the contents and cell origins of apoptotic bodies by flow cytometry

artículo científico publicado en 2017

Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

artículo científico publicado en 2012

Divalent metal binding by histidine-rich glycoprotein differentially regulates higher order oligomerisation and proteolytic processing.

artículo científico publicado en 2016

Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two

artículo científico publicado en 2000

Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells.

artículo científico publicado en 2005

Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis

artículo científico publicado en 2018

Expression of recombinant soluble Fc epsilon RI: function and tissue distribution studies

artículo científico publicado en 1995

Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1

Fc gamma receptors: gene structure and receptor function

artículo científico publicado en 1992

Fine Structure Analysis of Interaction of FcεRI with IgE

artículo científico publicado en 1999

Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn2+ in Settings of Tissue Injury

artículo científico publicado en 2017

Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes

scientific article published on 04 December 2018

Heparanase and the hallmarks of cancer

scientific article published on 30 November 2020

Heparanase: a key enzyme involved in cell invasion

artículo científico publicado en 2001

Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions

artículo científico publicado en 2010

Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelation

artículo científico publicado en 2004

Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake.

artículo científico publicado en 2010

Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via Fc RI on phagocytes

artículo científico publicado en 2010

Histidine-rich glycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis

artículo científico publicado en 2005

Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems

artículo científico publicado en 2005

Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma

artículo científico publicado en 2011

Human HPA endoglycosidase heparanase. Map position 4q21.3.

artículo científico publicado en 1999

Human mast cell line-1 (HMC-1) cells transfected with FcεRIα are sensitive to IgE/antigen-mediated stimulation demonstrating selectivity towards cytokine production

artículo científico publicado en 2011

Human β-defensin 2 kills through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization

artículo científico publicado en 2018

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation.

artículo científico publicado en 2015

ICAM-1-dependent pathways regulate colonic eosinophilic inflammation.

artículo científico publicado en 2006

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

artículo científico publicado en 2000

Identification of residues in the first domain of human Fc alpha receptor essential for interaction with IgA

artículo científico publicado en 1999

Identification of the IgG binding site of the human low affinity receptor for IgG Fc gamma RII. Enhancement and ablation of binding by site-directed mutagenesis.

artículo científico

Identification of the immunoglobulin binding regions (IBR) of Fc gamma RII and Fc epsilon RI.

artículo científico publicado en 1992

Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process.

artículo científico publicado en 2003

Importance of phosphoinositide binding by human β-defensin 3 for Akt-dependent cytokine induction

artículo científico publicado en 2017

Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting

artículo científico publicado en 2017

Isolation, Tissue Distribution, and Chromosomal Localization of a Novel Testis-Specific Human Four-Transmembrane Gene Related to CD20 and FcϵRI-β

article

Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression

artículo científico publicado en 2019

Luminescent iridium(iii) complexes of N-heterocyclic carbene ligands prepared using the 'click reaction'

scientific article published on 01 July 2019

Mapping epitopes of human Fc gamma RII (CDw32) with monoclonal antibodies and recombinant receptors

artículo científico publicado en 1993

Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

artículo científico publicado en 2014

Molecular basis of Fc receptor function

artículo científico publicado en 1994

Molecular mechanisms of late apoptotic/necrotic cell clearance

artículo científico publicado en 2009

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry.

artículo científico publicado en 2016

Monoclonal antibodies and synthetic peptides define the active site of FcεRI and a potential receptor antagonist

scientific article published on 01 July 2000

Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles

scientific article published on 26 April 2019

Multiple regions of human Fc gamma RII (CD32) contribute to the binding of IgG.

artículo científico publicado en 1995

Murine histidine-rich glycoprotein: cloning, characterization and cellular origin

artículo científico publicado en 2000

Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.

artículo científico publicado en 2002

NK cell heparanase controls tumor invasion and immune surveillance

artículo científico publicado en 2017

New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties

artículo científico publicado en 2013

Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant ⬇️

artículo científico publicado en 2016

Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey

article

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

artículo científico publicado en 2014

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

scientific article published on 11 February 2019

Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein

artículo científico publicado en 2004

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

artículo científico publicado en 2019

ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly

scientific article published on 01 May 2019

Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis

artículo científico publicado en 2012

Redirected cytotoxic effector function. Requirements for expression of chimeric single chain high affinity immunoglobulin e receptors.

artículo científico publicado en 1996

Regulation of Inducible Heparanase Gene Transcription in Activated T Cells by Early Growth Response 1

scientific article published in Journal of Biological Chemistry

Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage

artículo científico publicado en 2009

Regulation of mouse Heparanase gene expression in T lymphocytes and tumor cells.

artículo científico publicado en 2007

Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity

artículo científico publicado en 2023

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

artículo científico publicado en 2019

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4.

artículo científico publicado en 2014

Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis

artículo científico publicado en 2017

Structural and functional characterization of the membrane-permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis

scientific article published on 22 February 2019

Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type

artículo científico publicado en 2017

Structure of the mouse beta Fc gamma receptor II gene

article

TREML4 receptor regulates inflammation and innate immune cell death during polymicrobial sepsis

artículo científico publicado en 2020

The Defensins Consist of Two Independent, Convergent Protein Superfamilies ⬇️

artículo científico publicado en 2016

The MS4A family: counting past 1, 2 and 3.

artículo científico

The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis.

artículo científico publicado en 2015

The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes

artículo científico publicado en 2012

The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells.

artículo científico publicado en 2017

The phospholipid code: a key component of dying cell recognition, tumor progression and host-microbe interactions

artículo científico

The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process.

artículo científico publicado en 2017

The plant defensin NaD1 introduces membrane disorder through a specific interaction with the lipid, phosphatidylinositol 4,5 bisphosphate ⬇️

artículo científico publicado en 2016

The relationship between CCR6 and its binding partners: does the CCR6-CCL20 axis have to be extended?

artículo científico publicado en 2015

The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a

artículo científico publicado en 1998

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects

artículo científico publicado en 2017

Use of the 5'-flanking region of the mouse perforin gene to express human Fc gamma receptor I in cytotoxic T lymphocytes

artículo científico publicado en 1994

X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.

artículo científico publicado en 2018

Yin Yang-1 inhibits tumor cell growth and inhibits p21WAF1/Cip1 complex formation with cdk4 and cyclin D1.

artículo científico publicado en 2012

Lista de obras de Mark D Hulett

A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

Access to the Parent Tetrakis(pyridine)gold(III) Trication, Facile Formation of Rare Au(III) Terminal Hydroxides, and Preliminary Studies of Biological Properties

Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer

Cell surface expression of a peptide encoded by the unrearranged TCR-Vbeta8.2 gene.

Cell surface-expressed cation-independent mannose 6-phosphate receptor (CD222) binds enzymatically active heparanase independently of mannose 6-phosphate to promote extracellular matrix degradation

Characterization of FcR Ig-binding sites and epitope mapping

Chimeric Fc receptors identify functional domains of the murine high affinity receptor for IgG.

Chimeric Fc receptors identify immunoglobulin-binding regions in human Fc gamma RII and Fc epsilon RI.

Cloning and characterization of a mouse homologue of the human haematopoietic cell-specific four-transmembrane gene HTm4

Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5'-flanking sequences

Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

Combating Human Pathogens and Cancer by Targeting Phosphoinositides and Their Metabolism

Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma

Convergent evolution of defensin sequence, structure and function ⬇️

Crystal structure of the human leukocyte Fc receptor, Fc gammaRIIa

Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1.

Defining the morphologic features and products of cell disassembly during apoptosis.

Defining the role of cytoskeletal components in the formation of apoptopodia and apoptotic bodies during apoptosis

Determining the contents and cell origins of apoptotic bodies by flow cytometry

Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

Divalent metal binding by histidine-rich glycoprotein differentially regulates higher order oligomerisation and proteolytic processing.

Domain One of the High Affinity IgE Receptor, FcεRI, Regulates Binding to IgE through Its Interface with Domain Two

Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells.

Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis

Expression of recombinant soluble Fc epsilon RI: function and tissue distribution studies

Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1

Fc gamma receptors: gene structure and receptor function

Fine Structure Analysis of Interaction of FcεRI with IgE

Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn2+ in Settings of Tissue Injury

Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes

Heparanase and the hallmarks of cancer

Heparanase: a key enzyme involved in cell invasion

Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions

Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelation

Histidine-rich glycoprotein functions cooperatively with cell surface heparan sulfate on phagocytes to promote necrotic cell uptake.

Histidine-rich glycoprotein is a novel plasma pattern recognition molecule that recruits IgG to facilitate necrotic cell clearance via Fc RI on phagocytes

Histidine-rich glycoprotein specifically binds to necrotic cells via its amino-terminal domain and facilitates necrotic cell phagocytosis

Histidine-rich glycoprotein: A novel adaptor protein in plasma that modulates the immune, vascular and coagulation systems

Histidine-rich glycoprotein: the Swiss Army knife of mammalian plasma

Human HPA endoglycosidase heparanase. Map position 4q21.3.

Human mast cell line-1 (HMC-1) cells transfected with FcεRIα are sensitive to IgE/antigen-mediated stimulation demonstrating selectivity towards cytokine production

Human β-defensin 2 kills through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation.

ICAM-1-dependent pathways regulate colonic eosinophilic inflammation.

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

Identification of residues in the first domain of human Fc alpha receptor essential for interaction with IgA

Identification of the IgG binding site of the human low affinity receptor for IgG Fc gamma RII. Enhancement and ablation of binding by site-directed mutagenesis.

Identification of the immunoglobulin binding regions (IBR) of Fc gamma RII and Fc epsilon RI.

Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process.

Importance of phosphoinositide binding by human β-defensin 3 for Akt-dependent cytokine induction

Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting

Isolation, Tissue Distribution, and Chromosomal Localization of a Novel Testis-Specific Human Four-Transmembrane Gene Related to CD20 and FcϵRI-β

Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression

Luminescent iridium(iii) complexes of N-heterocyclic carbene ligands prepared using the 'click reaction'

Mapping epitopes of human Fc gamma RII (CDw32) with monoclonal antibodies and recombinant receptors

Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

Molecular basis of Fc receptor function

Molecular mechanisms of late apoptotic/necrotic cell clearance

Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry.

Monoclonal antibodies and synthetic peptides define the active site of FcεRI and a potential receptor antagonist

Moving beyond size and phosphatidylserine exposure: evidence for a diversity of apoptotic cell-derived extracellular vesicles

Multiple regions of human Fc gamma RII (CD32) contribute to the binding of IgG.

Murine histidine-rich glycoprotein: cloning, characterization and cellular origin

Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.

NK cell heparanase controls tumor invasion and immune surveillance

New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties

Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant ⬇️

Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly

Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis

Redirected cytotoxic effector function. Requirements for expression of chimeric single chain high affinity immunoglobulin e receptors.