Lista de obras - Ralph Witzgall - Dominio Público Uruguay

A mammalian expression vector for the expression of GAL4 fusion proteins with an epitope tag and histidine tail

artículo científico publicado en 1994

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts

artículo científico publicado en 2021

A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats

scientific article published on 30 August 2006

Advanced electron microscopic techniques provide a deeper insight into the peculiar features of podocytes

artículo científico publicado en 2015

Altered expression pattern of polycystin-2 in acute and chronic renal tubular diseases

scientific journal article

An endocytosis defect as a possible cause of proteinuria in polycystic kidney disease

artículo científico publicado en 2001

Are renal proximal tubular epithelial cells constantly prepared for an emergency? Focus on "the proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells"

artículo científico publicado en 2007

Biodistribution of quantum dots in the kidney after intravenous injection

artículo científico publicado en 2014

Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.

artículo científico publicado en 2009

Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A

scientific article published on 29 November 2010

Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1.

artículo científico publicado en 2001

Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells

artículo científico publicado en 1996

Differentiation and cell polarity during renal cyst formation in the Han:SPRD (cy/+) rat, a model for ADPKD.

artículo científico publicado en 1997

Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease

artículo científico publicado en 2009

ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel.

artículo científico publicado en 2009

Expression of clusterin in Crohn's disease of the terminal ileum

scientific article published on 01 July 2001

Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules.

artículo científico publicado en 1997

Genomic structure and chromosomal location of the rat gene encoding the zinc finger transcription factor Kid-1.

artículo científico publicado en 1994

How are podocytes affected in nail-patella syndrome?

artículo científico publicado en 2008

Identification and characterization of polycystin-2, the PKD2 gene product

artículo científico publicado en 1999

Impaired endocytosis may represent an obstacle to gene therapy in polycystic kidney disease

artículo científico publicado en 2002

Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance

artículo científico publicado en 2015

Intravital Imaging Reveals Angiotensin II-Induced Transcytosis of Albumin by Podocytes.

artículo científico publicado en 2015

Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia.

artículo científico publicado en 1998

Kid-1, a kidney transcription factor

scientific article published on 01 May 1995

Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles.

artículo científico publicado en 2012

LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys

artículo científico publicado en 2013

Lack of a laterality phenotype in Pkd1 knock-out embryos correlates with absence of polycystin-1 in nodal cilia

scientific journal article

Lack of connexin 40 causes displacement of renin-producing cells from afferent arterioles to the extraglomerular mesangium

scientific article published on 28 February 2007

Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

artículo científico publicado en 1994

Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.

artículo científico publicado en 2005

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome

artículo científico publicado en 2014

Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.

artículo científico publicado en 2008

Mutations of the Uromodulin gene in MCKD type 2 patients cluster in exon 4, which encodes three EGF-like domains

artículo científico publicado en 2003

NMR-assignments of a cytosolic domain of the C-terminus of polycystin-2

artículo científico publicado en 2009

Nail-patella syndrome

scientific article published on 05 July 2017

Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function

artículo científico publicado en 2016

New developments in the field of cystic kidney diseases.

artículo científico publicado en 2005

Nonspecific cation current associated with native polycystin-2 in HEK-293 cells.

artículo científico publicado en 2006

Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells

artículo científico publicado en 2008

PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2

artículo científico publicado en 2004

Phospholipase A(2) and Lipids as Potential Modulators of c-Raf-1 Kinase

artículo científico publicado en 1996

Phosphorylation of C-terminal polycystin-2 influences the interaction with PIGEA14: a QCM study based on solid supported membranes

artículo científico publicado en 2013

Photochemically Active Fluorophore-DNA/RNA Conjugates for Cellular Imaging of Nucleic Acids by Readout in Electron Microscopy

artículo científico publicado en 2013

Polycystic kidney disease--a tale of calcium channels and the actin cytoskeleton

artículo científico publicado en 2001

Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells

artículo científico publicado en 2006

Polycystin-2 takes different routes to the somatic and ciliary plasma membrane

artículo científico publicado en 2011

Polycystin-2--an intracellular or plasma membrane channel?

artículo científico publicado en 2005

Quantifying the interaction of the C-terminal regions of polycystin-2 and polycystin-1 attached to a lipid bilayer by means of QCM

artículo científico publicado en 2010

Regulation of clusterin expression following spinal cord injury

artículo científico publicado en 2001

Renal osmotic stress-induced cotransporter: expression in the newborn, adult and post-ischemic rat kidney

artículo científico publicado en 1997

Renal phenotype in heterozygous Lmx1b knockout mice (Lmx1b+/-) after unilateral nephrectomy

scientific article published on 27 July 2007

Role of transcription factors in podocytes

scientific article published on 06 June 2007

Soluble interleukin-2 receptors inhibit interleukin 2-dependent proliferation and cytotoxicity: explanation for diminished natural killer cell activity in cutaneous T-cell lymphomas in vivo?

artículo científico publicado en 1992

TRPP2 channel regulation

artículo científico publicado en 2007

The Krüppel-associated box (KRAB)-zinc finger protein Kid-1 and the Wilms' tumor protein WT1, two transcriptional repressor proteins, bind to heteroduplex DNA

scientific article published on 01 October 1997

The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.

artículo científico publicado en 1994

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes

artículo científico publicado en 2002

The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function

artículo científico publicado en 2014

The human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-termini ⬇️

artículo científico publicado el 15 de enero de 2011

The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes

artículo científico publicado en 2007

The proximal tubule phenotype and its disruption in acute renal failure and polycystic kidney disease.

artículo científico publicado en 1999

The rat pkd2 protein assumes distinct subcellular distributions in different organs

artículo científico publicado en 1999

The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells

artículo científico publicado en 1998

Up-regulation of the human serum and glucocorticoid-dependent kinase 1 in glomerulonephritis

artículo científico publicado en 2002

Use of the tetracycline system for inducible protein synthesis in the kidney

artículo científico publicado en 2003

Lista de obras de Ralph Witzgall

A mammalian expression vector for the expression of GAL4 fusion proteins with an epitope tag and histidine tail

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts

A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats

Advanced electron microscopic techniques provide a deeper insight into the peculiar features of podocytes

Altered expression pattern of polycystin-2 in acute and chronic renal tubular diseases

An endocytosis defect as a possible cause of proteinuria in polycystic kidney disease

Are renal proximal tubular epithelial cells constantly prepared for an emergency? Focus on "the proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells"

Biodistribution of quantum dots in the kidney after intravenous injection

Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.

Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A

Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1.

Cytosolic phospholipase A2 (PLA2), but not secretory PLA2, potentiates hydrogen peroxide cytotoxicity in kidney epithelial cells

Differentiation and cell polarity during renal cyst formation in the Han:SPRD (cy/+) rat, a model for ADPKD.

Doxycycline accelerates renal cyst growth and fibrosis in the pcy/pcy mouse model of type 3 nephronophthisis, a form of recessive polycystic kidney disease

ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel.

Expression of clusterin in Crohn's disease of the terminal ileum

Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules.

Genomic structure and chromosomal location of the rat gene encoding the zinc finger transcription factor Kid-1.

How are podocytes affected in nail-patella syndrome?

Identification and characterization of polycystin-2, the PKD2 gene product

Impaired endocytosis may represent an obstacle to gene therapy in polycystic kidney disease

Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance

Intravital Imaging Reveals Angiotensin II-Induced Transcytosis of Albumin by Podocytes.

Kid-1 expression is high in differentiated renal proximal tubule cells and suppressed in cyst epithelia.

Kid-1, a kidney transcription factor

Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles.

LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys

Lack of a laterality phenotype in Pkd1 knock-out embryos correlates with absence of polycystin-1 in nodal cilia

Lack of connexin 40 causes displacement of renin-producing cells from afferent arterioles to the extraglomerular mesangium

Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome

Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2.

Mutations of the Uromodulin gene in MCKD type 2 patients cluster in exon 4, which encodes three EGF-like domains

NMR-assignments of a cytosolic domain of the C-terminus of polycystin-2

Nail-patella syndrome

Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function

New developments in the field of cystic kidney diseases.

Nonspecific cation current associated with native polycystin-2 in HEK-293 cells.

Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells

PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2

Phospholipase A(2) and Lipids as Potential Modulators of c-Raf-1 Kinase

Phosphorylation of C-terminal polycystin-2 influences the interaction with PIGEA14: a QCM study based on solid supported membranes

Photochemically Active Fluorophore-DNA/RNA Conjugates for Cellular Imaging of Nucleic Acids by Readout in Electron Microscopy

Polycystic kidney disease--a tale of calcium channels and the actin cytoskeleton

Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells

Polycystin-2 takes different routes to the somatic and ciliary plasma membrane

Polycystin-2--an intracellular or plasma membrane channel?

Quantifying the interaction of the C-terminal regions of polycystin-2 and polycystin-1 attached to a lipid bilayer by means of QCM

Regulation of clusterin expression following spinal cord injury

Renal osmotic stress-induced cotransporter: expression in the newborn, adult and post-ischemic rat kidney

Renal phenotype in heterozygous Lmx1b knockout mice (Lmx1b+/-) after unilateral nephrectomy

Role of transcription factors in podocytes

Soluble interleukin-2 receptors inhibit interleukin 2-dependent proliferation and cytotoxicity: explanation for diminished natural killer cell activity in cutaneous T-cell lymphomas in vivo?

TRPP2 channel regulation

The Krüppel-associated box (KRAB)-zinc finger protein Kid-1 and the Wilms' tumor protein WT1, two transcriptional repressor proteins, bind to heteroduplex DNA

The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression.

The LIM-homeodomain transcription factor Lmx1b plays a crucial role in podocytes

The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function

The human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-termini ⬇️

The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes

The proximal tubule phenotype and its disruption in acute renal failure and polycystic kidney disease.

The rat pkd2 protein assumes distinct subcellular distributions in different organs

The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells

Up-regulation of the human serum and glucocorticoid-dependent kinase 1 in glomerulonephritis

Use of the tetracycline system for inducible protein synthesis in the kidney