Lista de obras - David E. MacHugh - Dominio Público Uruguay

A Population Genomics Analysis of the Native Irish Galway Sheep Breed

scientific article published on 08 October 2019

A catalogue of validated single nucleotide polymorphisms in bovine orthologs of mammalian imprinted genes and associations with beef production traits.

artículo científico publicado en 2010

A complete mitochondrial genome sequence from a mesolithic wild aurochs (Bos primigenius)

artículo científico publicado en 2010

A genome scan for positive selection in thoroughbred horses

artículo científico publicado en 2009

A genome-wide SNP-association study confirms a sequence variant (g.66493737C>T) in the equine myostatin (MSTN) gene as the most powerful predictor of optimum racing distance for Thoroughbred racehorses

artículo científico publicado en 2010

A genomic prediction model for racecourse starts in the Thoroughbred horse

artículo científico publicado en 2019

A microsatellite survey of cattle from a centre of origin: the Near East

artículo científico publicado en 1999

A sequence polymorphism in MSTN predicts sprinting ability and racing stamina in thoroughbred horses

artículo científico publicado en 2010

Admixture and diversity in West African cattle populations

article

Alterations in oxidative gene expression in equine skeletal muscle following exercise and training

artículo científico publicado en 2009

Alveolar macrophage chromatin is uniquely modified to orchestrate host response to Mycobacterium bovis infection

Analysis of genetic variation contributing to measured speed in Thoroughbreds identifies genomic regions involved in the transcriptional response to exercise

artículo científico publicado en 2019

Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq

artículo científico publicado en 2015

Ancient DNA analysis of 101 cattle remains: limits and prospects

article

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

scientific article published on 01 July 2019

Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program

artículo científico publicado en 2008

Association of sequence variants in CKM (creatine kinase, muscle) and COX4I2 (cytochrome c oxidase, subunit 4, isoform 2) genes with racing performance in Thoroughbred horses

article

Associations between newly discovered polymorphisms in the Bos taurusgrowth hormone receptor gene and performance traits in Holstein-Friesian dairy cattle

article

Associations between novel single nucleotide polymorphisms in the Bos taurus growth hormone gene and performance traits in Holstein-Friesian dairy cattle

article

Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training

artículo científico publicado en 2010

Chinese Mongolian horses may retain early domestic male genetic lineages yet to be discovered

artículo científico publicado en 2019

Circulating microRNAs as Potential Biomarkers of Infectious Disease

artículo científico publicado en 2017

Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

artículo científico publicado en 2018

Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus

artículo científico publicado en 2014

Comparative ’omics analyses differentiateMycobacterium tuberculosisandMycobacterium bovisand reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

article

Convenient detection of single nucleotide polymorphism haplotypes in the bovine growth hormone gene using amplification-created restriction sites

artículo científico publicado en 2005

Correction: A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses.

artículo científico publicado en 2010

Cytokine mRNA profiling of peripheral blood mononuclear cells from trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense.

artículo científico publicado en 2006

DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle

artículo científico publicado en 2010

DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits

artículo científico publicado en 2011

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts

artículo científico publicado en 2014

Dietary n-3 polyunsaturated fatty acid supplementation alters the expression of genes involved in the control of fertility in the bovine uterine endometrium

article

Differential gene expression in the endometrium reveals cytoskeletal and immunological genes in lactating dairy cows genetically divergent for fertility traits

article by Bruce Moran et al published 2015 in Reproduction, Fertility and Development

Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle

artículo científico publicado en 2009

Domestication of cattle: Two or three events?

artículo científico publicado en 2018

Early medieval cattle remains from a Scandinavian settlement in Dublin: genetic analysis and comparison with extant breeds

artículo científico publicado en 1999

Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components

artículo científico

Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations.

artículo científico publicado en 2006

Evidence for two independent domestications of cattle.

artículo científico publicado en 1994

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome

scientific article published on 26 November 2019

Fasciola hepatica Infection in Cattle: Analyzing Responses of Peripheral Blood Mononuclear Cells (PBMC) Using a Transcriptomics Approach

scientific article published on 29 August 2019

Feasibility and utility of microsatellite markers in archaeological cattle remains from a Viking Age settlement in Dublin.

artículo científico publicado en 2003

Functional characterisation of bovine interleukin 8 promoter haplotypes in vitro

artículo científico publicado en 2012

GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data

artículo científico publicado en 2016

Gene expression profiling of peripheral blood mononuclear cells (PBMC) from Mycobacterium bovis infected cattle after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD).

artículo científico publicado en 2006

Gene expression profiling of the host response to Mycobacterium bovis infection in cattle

scientific article published on 26 May 2009

Genetic contributions to precocity traits in racing Thoroughbreds.

artículo científico publicado en 2017

Genetic evidence for Near-Eastern origins of European cattle

artículo científico publicado en 2001

Genetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattle

artículo científico publicado en 2016

Genetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattle

artículo científico publicado en 2017

Genetic structure of seven European cattle breeds assessed using 20 microsatellite markers

artículo científico publicado en 1998

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

artículo científico publicado en 2015

Genome-Wide microRNA Binding Site Variation between Extinct Wild Aurochs and Modern Cattle Identifies Candidate microRNA-Regulated Domestication Genes

scientific article published on 31 January 2017

Genome-wide SNP association-based localization of a dwarfism gene in Friesian dwarf horses

article

Genome-wide association study of osteochondrosis in the tarsocrural joint of Dutch Warmblood horses identifies susceptibility loci on chromosomes 3 and 10.

artículo científico publicado en 2012

Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes

artículo científico publicado en 2011

Genomic Characterisation of the Indigenous Irish Kerry Cattle Breed

artículo científico publicado en 2018

Genomic characterisation and conservation genetics of the indigenous Irish Kerry cattle breed

article

Genomic imprinting effects on complex traits in domesticated animal species

artículo científico publicado en 2015

Genomics of Performance

Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis

artículo científico publicado en 2012

High concordance of bovine single nucleotide polymorphism genotypes generated using two independent genotyping strategies

artículo científico publicado en 2010

High-throughput transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium abscessus Smooth and Rough variants

artículo científico publicado en 2015

Horses for courses: a DNA-based test for race distance aptitude in thoroughbred racehorses

artículo científico publicado en 2012

Impact of delayed processing of bovine peripheral blood on differential gene expression

artículo científico publicado en 2011

Imprinted loci in domestic livestock species as epigenomic targets for artificial selection of complex traits.

artículo científico publicado en 2014

Inbreeding effects on postweaning production traits, conformation, and calving performance in Irish beef cattle

article

Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection

article

Innate gene repression associated with Mycobacterium bovis infection in cattle: toward a gene signature of disease

artículo científico publicado en 2007

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria

artículo científico publicado en 2021

Iodine supplementation of the pregnant dam alters intestinal gene expression and immunoglobulin uptake in the newborn lamb.

artículo científico publicado en 2015

Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis

artículo científico publicado en 2014

Linkage mapping of the locus for inherited ovine arthrogryposis (IOA) to sheep Chromosome 5

artículo científico publicado en 2007

Livestock genetic origins: goats buck the trend.

artículo científico publicado en 2001

Long-term stability of RNA in post-mortem bovine skeletal muscle, liver and subcutaneous adipose tissues

artículo científico publicado en 2007

MSTN genotype (g.66493737C/T) association with speed indices in Thoroughbred racehorses

MSTN genotypes in Thoroughbred horses influence skeletal muscle gene expression and racetrack performance

artículo científico publicado en 2012

MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking.

artículo científico publicado en 2015

Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus)

artículo científico publicado en 1997

Microsatellite DNA variation within and among European cattle breeds

artículo científico publicado en 1994

Mitochondrial diversity and the origins of African and European cattle

artículo científico publicado en 1996

Mitochondrial genetic variation in European, African and Indian cattle populations.

artículo científico publicado en 1994

Moderate and high intensity sprint exercise induce differential responses in COX4I2 and PDK4 gene expression in Thoroughbred horse skeletal muscle

article

PGC-1α encoded by the PPARGC1A gene regulates oxidative energy metabolism in equine skeletal muscle during exercise.

artículo científico publicado en 2011

PHLDA2 is an imprinted gene in cattle

artículo científico publicado en 2011

Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis

artículo científico publicado en 2012

Phylogenetic analysis of the tribe Bovini using microsatellites

artículo científico publicado en 2000

Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples

artículo científico publicado en 2012

Prehistoric genomes reveal the genetic foundation and cost of horse domestication

artículo científico publicado en 2014

Profiling microRNA expression in bovine alveolar macrophages using RNA-seq

artículo científico publicado en 2013

RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses () and Cattle ()

article

RNA sequencing (RNA-seq) reveals extremely low levels of reticulocyte-derived globin gene transcripts in peripheral blood from horses (Equus caballus) and cattle (Bos taurus)

article

RNA sequencing provides exquisite insight into the manipulation of the alveolar macrophage by tubercle bacilli

artículo científico publicado en 2015

RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis

artículo científico publicado en 2014

Receptor-mediated recognition of mycobacterial pathogens

artículo científico

Refinement of Global Domestic Horse Biogeography Using Historic Landrace Chinese Mongolian Populations

scientific article published on 19 October 2019

Selection in Australian Thoroughbred horses acts on a locus associated with early two-year old speed

scientific article published on 12 February 2020

Sequence variation in the mitochondrial DNA control region of wild African cheetahs (Acinonyx jubatus).

artículo científico publicado en 2001

Single nucleotide polymorphisms at the imprinted bovine insulin-like growth factor 2 (IGF2) locus are associated with dairy performance in Irish Holstein-Friesian cattle.

artículo científico publicado en 2010

Single nucleotide polymorphisms in the imprinted bovine insulin-like growth factor 2 receptor gene (IGF2R) are associated with body size traits in Irish Holstein-Friesian cattle.

artículo científico publicado en 2011

Single nucleotide polymorphisms within the bovine DLK1-DIO3 imprinted domain are associated with economically important production traits in cattle.

artículo científico publicado en 2010

Taming the Past: Ancient DNA and the Study of Animal Domestication

artículo científico publicado en 2017

Targets of selection in the Thoroughbred genome contain exercise-relevant gene SNPs associated with elite racecourse performance

article

Technical note: High fidelity of whole-genome amplified sheep (Ovis aries) deoxyribonucleic acid using a high-density single nucleotide polymorphism array-based genotyping platform

artículo científico publicado en 2010

The Identification of Circulating MiRNA in Bovine Serum and Their Potential as Novel Biomarkers of Early Mycobacterium avium subsp paratuberculosis Infection

artículo científico publicado en 2015

The MarR family transcription factor Rv1404 coordinates adaptation of Mycobacterium tuberculosis to acid stress via controlled expression of Rv1405c, a virulence-associated methyltransferase

artículo científico publicado en 2015

The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis

artículo científico publicado en 2019

The genetic origin and history of speed in the Thoroughbred racehorse.

artículo científico publicado en 2012

Transcriptional adaptations following exercise in thoroughbred horse skeletal muscle highlights molecular mechanisms that lead to muscle hypertrophy

artículo científico publicado en 2009

Transcriptional profiling of cattle infected with Trypanosoma congolense highlights gene expression signatures underlying trypanotolerance and trypanosusceptibility

artículo científico publicado en 2009

Transcriptional profiling of immune genes in bovine monocyte-derived macrophages exposed to bacterial antigens.

artículo científico publicado en 2010

Transmission ratio distortion at the growth hormone gene (GH1) in bovine preimplantation embryos: An in vitro culture-induced phenomenon?

artículo científico publicado en 2008

Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells

artículo científico publicado en 2007

Understanding bovine trypanosomiasis and trypanotolerance: the promise of functional genomics

artículo científico publicado en 2005

Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics ⬇️

scientific article published on 02 December 2019

Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis

artículo científico publicado en 2024

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro

artículo científico publicado en 2013

Y-specific microsatellite polymorphisms in a range of bovid species

artículo científico publicado en 2000

Zebu-taurine variation in Y chromosomal DNA: a sensitive assay for genetic introgression in west African trypanotolerant cattle populations

artículo científico publicado en 1994

Lista de obras de David E. MacHugh

A Population Genomics Analysis of the Native Irish Galway Sheep Breed

A catalogue of validated single nucleotide polymorphisms in bovine orthologs of mammalian imprinted genes and associations with beef production traits.

A complete mitochondrial genome sequence from a mesolithic wild aurochs (Bos primigenius)

A genome scan for positive selection in thoroughbred horses

A genome-wide SNP-association study confirms a sequence variant (g.66493737C>T) in the equine myostatin (MSTN) gene as the most powerful predictor of optimum racing distance for Thoroughbred racehorses

A genomic prediction model for racecourse starts in the Thoroughbred horse

A microsatellite survey of cattle from a centre of origin: the Near East

A sequence polymorphism in MSTN predicts sprinting ability and racing stamina in thoroughbred horses

Admixture and diversity in West African cattle populations

Alterations in oxidative gene expression in equine skeletal muscle following exercise and training

Alveolar macrophage chromatin is uniquely modified to orchestrate host response to Mycobacterium bovis infection

Analysis of genetic variation contributing to measured speed in Thoroughbreds identifies genomic regions involved in the transcriptional response to exercise

Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq

Ancient DNA analysis of 101 cattle remains: limits and prospects

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program

Association of sequence variants in CKM (creatine kinase, muscle) and COX4I2 (cytochrome c oxidase, subunit 4, isoform 2) genes with racing performance in Thoroughbred horses

Associations between newly discovered polymorphisms in the Bos taurusgrowth hormone receptor gene and performance traits in Holstein-Friesian dairy cattle

Associations between novel single nucleotide polymorphisms in the Bos taurus growth hormone gene and performance traits in Holstein-Friesian dairy cattle

Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training

Chinese Mongolian horses may retain early domestic male genetic lineages yet to be discovered

Circulating microRNAs as Potential Biomarkers of Infectious Disease

Comparative 'omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus

Comparative ’omics analyses differentiateMycobacterium tuberculosisandMycobacterium bovisand reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

Convenient detection of single nucleotide polymorphism haplotypes in the bovine growth hormone gene using amplification-created restriction sites

Correction: A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses.

Cytokine mRNA profiling of peripheral blood mononuclear cells from trypanotolerant and trypanosusceptible cattle infected with Trypanosoma congolense.

DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle

DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts

Dietary n-3 polyunsaturated fatty acid supplementation alters the expression of genes involved in the control of fertility in the bovine uterine endometrium

Differential gene expression in the endometrium reveals cytoskeletal and immunological genes in lactating dairy cows genetically divergent for fertility traits

Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle

Domestication of cattle: Two or three events?

Early medieval cattle remains from a Scandinavian settlement in Dublin: genetic analysis and comparison with extant breeds

Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components

Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations.

Evidence for two independent domestications of cattle.

Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome

Fasciola hepatica Infection in Cattle: Analyzing Responses of Peripheral Blood Mononuclear Cells (PBMC) Using a Transcriptomics Approach

Feasibility and utility of microsatellite markers in archaeological cattle remains from a Viking Age settlement in Dublin.

Functional characterisation of bovine interleukin 8 promoter haplotypes in vitro

GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data

Gene expression profiling of peripheral blood mononuclear cells (PBMC) from Mycobacterium bovis infected cattle after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD).

Gene expression profiling of the host response to Mycobacterium bovis infection in cattle

Genetic contributions to precocity traits in racing Thoroughbreds.

Genetic evidence for Near-Eastern origins of European cattle

Genetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattle

Genetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattle

Genetic structure of seven European cattle breeds assessed using 20 microsatellite markers

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

Genome-Wide microRNA Binding Site Variation between Extinct Wild Aurochs and Modern Cattle Identifies Candidate microRNA-Regulated Domestication Genes

Genome-wide SNP association-based localization of a dwarfism gene in Friesian dwarf horses

Genome-wide association study of osteochondrosis in the tarsocrural joint of Dutch Warmblood horses identifies susceptibility loci on chromosomes 3 and 10.

Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes

Genomic Characterisation of the Indigenous Irish Kerry Cattle Breed

Genomic characterisation and conservation genetics of the indigenous Irish Kerry cattle breed

Genomic imprinting effects on complex traits in domesticated animal species

Genomics of Performance

Global gene expression and systems biology analysis of bovine monocyte-derived macrophages in response to in vitro challenge with Mycobacterium bovis

High concordance of bovine single nucleotide polymorphism genotypes generated using two independent genotyping strategies

High-throughput transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium abscessus Smooth and Rough variants

Horses for courses: a DNA-based test for race distance aptitude in thoroughbred racehorses

Impact of delayed processing of bovine peripheral blood on differential gene expression

Imprinted loci in domestic livestock species as epigenomic targets for artificial selection of complex traits.

Inbreeding effects on postweaning production traits, conformation, and calving performance in Irish beef cattle

Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection

Innate gene repression associated with Mycobacterium bovis infection in cattle: toward a gene signature of disease

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria

Iodine supplementation of the pregnant dam alters intestinal gene expression and immunoglobulin uptake in the newborn lamb.

Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis

Linkage mapping of the locus for inherited ovine arthrogryposis (IOA) to sheep Chromosome 5

Livestock genetic origins: goats buck the trend.

Long-term stability of RNA in post-mortem bovine skeletal muscle, liver and subcutaneous adipose tissues

MSTN genotype (g.66493737C/T) association with speed indices in Thoroughbred racehorses

MSTN genotypes in Thoroughbred horses influence skeletal muscle gene expression and racetrack performance

MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking.

Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus)