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Lista de obras de David Melzer

A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses

artículo científico publicado en 2006

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

artículo científico publicado en 2007

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

artículo científico publicado en 2007

A common variant of the p16(INK4a) genetic region is associated with physical function in older people

artículo científico publicado en 2007

A common variation in deiodinase 1 gene DIO1 is associated with the relative levels of free thyroxine and triiodothyronine

artículo científico publicado en 2008

A genome-wide association search for type 2 diabetes genes in African Americans

artículo científico publicado en 2012

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

artículo científico publicado en 2008

A genome-wide association study of depressive symptoms

scientific journal article

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

artículo científico publicado en 2009

A meta-analysis of gene expression signatures of blood pressure and hypertension

artículo científico publicado en 2015

A reference panel of 64,976 haplotypes for genotype imputation

artículo científico publicado en 2016

A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking

artículo científico publicado en 2016

Accelerating the Search for Interventions Aimed at Expanding the Health Span in Humans: The Role of Epidemiology

artículo científico publicado en 2020

Access to medium secure psychiatric care in England and Wales. 1: A national survey of admission assessments

article

Access to medium secure psychiatric care in England and Wales. 2: A qualitative study of admission decision-making

article

Access to medium secure psychiatric care in England and Wales. 3: The clinical needs of assessed patients

article

Adjusting for unmeasured confounding in non-randomised longitudinal studies: a methodological review

artículo científico publicado en 2017

Advancing age is associated with gene expression changes resembling mTOR inhibition: evidence from two human populations

scientific article published on 16 July 2012

Aftercare of depressed inpatients--service delivery and unmet needs

artículo científico publicado en 2003

Age-related impairments of mobility associated with cobalt and other heavy metals: data from NHANES 1999-2004.

artículo científico publicado en 2009

Aging children of long-lived parents experience slower cognitive decline.

artículo científico publicado en 2013

Albumin:creatinine ratio predicts mortality after stroke: analysis of the Third National Health and Nutrition Examination Survey.

artículo científico publicado en 2010

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

artículo científico publicado en 2011

An evaluation of a respite care unit for elderly people with dementia: framework and some results

artículo científico publicado en 1990

An interleukin-18 polymorphism is associated with reduced serum concentrations and better physical functioning in older people

artículo científico publicado en 2007

Another explanation for apparent epistasis

artículo científico publicado en 2014

Any versus long-term prescribing of high risk medications in older people using 2012 Beers Criteria: results from three cross-sectional samples of primary care records for 2003/4, 2007/8 and 2011/12. ⬇️

artículo científico publicado en 2015

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

artículo científico publicado en 2011

Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey

artículo científico publicado en 2010

Association of Bisphenol A With Diabetes and Other Abnormalities—Reply

scientific article published in The Journal of the American Medical Association

Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults

artículo científico publicado en 2008

Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06

artículo científico publicado en 2010

Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans

artículo científico publicado en 2013

Associations between socioeconomic status and environmental toxicant concentrations in adults in the USA: NHANES 2001-2010.

artículo científico publicado en 2013

Baby boomers nearing retirement: the healthiest generation?

artículo científico publicado en 2010

Bisphenol A and Adult Disease: Making Sense of Fragmentary Data and Competing Inferences

Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults

artículo científico publicado en 2011

Bisphenol A modulates the metabolic regulator oestrogen-related receptor-α in T-cells

artículo científico publicado en 2014

Blood Pressure Trajectories in the 20 Years Before Death.

artículo científico publicado en 2017

CARERS AND THE MONITORING OF PSYCHOGERIATRIC COMMUNITY TEAMS

CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength

artículo científico publicado en 2012

COVID-19 severity is predicted by earlier evidence of accelerated aging

scientific article published on 11 July 2020

Cell Specific eQTL Analysis without Sorting Cells

artículo científico publicado en 2015

Cell specific eQTL analysis without sorting cells

Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants

artículo científico publicado en 2017

Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise

artículo científico publicado en 2014

Changes in splicing factor expression are associated with advancing age in man.

artículo científico

Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.

artículo científico publicado en 2016

Chronological and Functional Ageing

Circulating beta-carotene levels and type 2 diabetes-cause or effect?

artículo científico publicado en 2009

Clinical Outcomes of CADASIL-Associated NOTCH3 Mutations in 451,424 European Ancestry Community Volunteers

Closing the gaps--enhancing the regulation of genetic tests using responsive regulation

artículo científico publicado en 2007

Cognitive impairment in elderly people: population based estimate of the future in England, Scotland, and Wales

artículo científico publicado en 1997

Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank

artículo científico publicado en 2019

Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels

article

Common health predictors of early retirement: findings from the English Longitudinal Study of Ageing

artículo científico publicado en 2011

Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people

artículo científico publicado en 2009

Common mental disorder symptom counts in populations: are there distinct case groups above epidemiological cut-offs?

artículo científico publicado en 2002

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

artículo científico publicado en 2008

Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study

artículo científico publicado en 2009

Community care for patients with schizophrenia one year after hospital discharge.

artículo científico publicado en 1991

Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts

artículo científico publicado en 2015

Comprehensive treatment for long-term mentally ill patients in UK

Computer-assisted diagnosis of focal liver lesions on CT images evaluation of the Perceptron algorithm

artículo científico publicado en 2005

Correction: Urinary Bisphenol A Concentration and Angiography-Defined Coronary Artery Stenosis.

artículo científico publicado en 2012

DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

artículo científico publicado en 2016

DNA methylation-based measures of biological age: meta-analysis predicting time to death

artículo científico publicado en 2016

Daily bisphenol A excretion and associations with sex hormone concentrations: results from the InCHIANTI adult population study

artículo científico publicado en 2010

Decline in Common Mental Disorder prevalence in men during the sixth decade of life. Evidence from the National Psychiatric Morbidity Survey

artículo científico publicado en 2004

Developing quality indicators for older adults: transfer from the USA to the UK is feasible

artículo científico publicado en 2004

Diversion from custody

artículo científico publicado en 1993

Donepezil for dementia due to Alzheimer's disease

artículo científico publicado en 2003

Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study. ⬇️

artículo científico publicado en 2014

Educational Differences in the Prevalence of Mobility Disability in Old Age: The Dynamics of Incidence, Mortality, and Recovery

article

Educational differences in the dynamics of disability incidence, recovery and mortality: Findings from the MRC Cognitive Function and Ageing Study (MRC CFAS)

article

Effects of the diabetes linked TCF7L2 polymorphism in a representative older population

artículo científico publicado en 2006

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

artículo científico publicado en 2011

Epidemiology of balance and dizziness in a national population: findings from the English Longitudinal Study of Ageing

artículo científico publicado en 2008

Epidemiology of balance and dizziness in a national population: findings from the English Longitudinal Study of Ageing

scholarly article by K. N. Stevens et al published 13 November 2008 in Age and Ageing

Epigenetic Signatures of Cigarette Smoking

artículo científico publicado en 2016

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Estrogen replacement therapy: new options, continuing concerns

artículo científico publicado en 1997

Events in Early Life are Associated with Female Reproductive Ageing: A UK Biobank Study

artículo científico publicado en 2016

Factors explaining the use of psychiatric services by general practices

artículo científico publicado en 1999

Filaggrin gene mutations are associated with asthma and eczema in later life

artículo científico publicado en 2008

Framingham Stroke Risk Profile and poor cognitive function: a population-based study

artículo científico publicado en 2008

Gene expression markers of age-related inflammation in two human cohorts

artículo científico publicado en 2015

Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons

artículo científico publicado en 2015

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes

artículo científico publicado en 2008

Genetic determinants of serum testosterone concentrations in men.

artículo científico publicado en 2011

Genetic polymorphisms and human aging: association studies deliver

artículo científico publicado en 2008

Genetic tests for common diseases: new insights, old concerns

artículo científico publicado en 2008

Genetic variation and human aging: progress and prospects

artículo científico publicado en 2007

Genetic variation associated with circulating monocyte count in the eMERGE Network

artículo científico publicado en 2013

Genetics and medicalisation

artículo científico publicado en 2002

Genome-wide Association Study of Parental Life Span

artículo científico publicado en 2017

Genomics and successful aging: grounds for renewed optimism?

artículo científico publicado en 2012

High urinary tungsten concentration is associated with stroke in the National Health and Nutrition Examination Survey 1999-2010.

artículo científico publicado en 2013

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

artículo científico publicado en 2011

Human genetic variations: Beacons on the pathways to successful ageing

artículo científico publicado en 2009

Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

artículo científico publicado en 2016

Human longevity: 25 genetic loci associated in 389,166 UK biobank participants

artículo científico publicado en 2017

Identifying likely causal connections between gene expression levels using a Mendelian randomization approach

article

Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation

artículo científico publicado en 2013

Incapacidade funcional entre as mulheres idosas no Brasil

Income and the midlife peak in common mental disorder prevalence

artículo científico publicado en 2010

Interleukin-18 polymorphism and physical functioning in older people: a replication study and meta-analysis

artículo científico publicado en 2009

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

Leukocyte CCR2 expression is associated with mini-mental state examination score in older adults

artículo científico publicado en 2012

Local population differences and the needs of people with cognitive impairment

Local population differences and the needs of people with cognitive impairment

artículo científico publicado en 1997

Longer lived parents: protective associations with cancer incidence and overall mortality

scientific article published on 16 May 2013

Longer-Lived Parents and Cardiovascular Outcomes

artículo científico publicado en 2016

Low prevalence of depression and anxiety is linked to statutory retirement ages rather than personal work exit: a national survey

artículo científico publicado en 2006

Medication received by patients with depression following the acute episode: adequacy and relation to outcome

artículo científico publicado en 1999

Mental health and the timing of men's retirement

artículo científico publicado en 2006

Mental health. Talk--don't inject

artículo científico publicado en 1992

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

artículo científico publicado en 2012

MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice.

artículo científico publicado en 2017

Middle-aged and mobility-limited: prevalence of disability and symptom attributions in a national survey

artículo científico publicado en 2006

Mobility disability in the middle-aged: cross-sectional associations in the English Longitudinal Study of Ageing

article

Moderate alcohol consumption in later life: time for a trial?

artículo científico publicado en 2009

Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence

artículo científico publicado en 2007

Much more medicine for the oldest old: trends in UK electronic clinical records ⬇️

artículo científico publicado en 2014

Multiple loci are associated with white blood cell phenotypes

artículo científico publicado en 2011

National mortality rates from chronic liver disease and consumption of alcohol and pig meat

artículo científico publicado en 2009

Need for and receipt of hip and knee replacement—a national population survey

article by N. Steel et al published 21 April 2006 in Rheumatology

Neighborhood Deprivation, Individual Socioeconomic Status, and Frailty in Older Adults

artículo científico publicado en 2009

Neighborhood deprivation, individual socioeconomic status, and cognitive function in older people: analyses from the English Longitudinal Study of Ageing

scientific article published on 24 December 2007

Neighbourhood deprivation and dental service use: a cross-sectional analysis of older people in England

article

Neighbourhood deprivation and incident mobility disability in older adults

artículo científico publicado en 2008

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

artículo científico publicado en 2010

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

artículo científico publicado en 2012

Obesity in Older People With and Without Conditions Associated With Weight Loss: Follow-up of 955,000 Primary Care Patients

artículo científico publicado en 2016

Obesity, physical function, and mortality in older adults.

artículo científico publicado en 2008

Outcomes of Treated Hypertension at Age 80 and Older: Cohort Analysis of 79,376 Individuals

artículo científico publicado en 2016

Patent protection for medical technologies: why some and not others? ⬇️

artículo científico publicado el 14 de febrero de 1998

Patient characteristics predicting failure to receive indicated care for type 2 diabetes ⬇️

artículo científico publicado en 2014

Paying for health services: A public health view

article

Performance tests and disability: developing an objective index of mobility-related limitation in older populations

artículo científico publicado en 2002

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations

artículo científico publicado en 2016

Personal paper: New drug treatment for Alzheimer's disease: lessons for healthcare policy ⬇️

artículo científico publicado el 7 de marzo de 1998

Personality profile of the children of long-lived parents

artículo científico publicado en 2013

Pharmacogenetics and public policy: expert views in Europe and North America

Pharmacogenetics: policy needs for personal prescribing

Pharmacogenetics: policy needs for personal prescribing

scientific article published on 01 January 2005

Physical activity in middle-aged adults reduces risks of functional impairment independent of its effect on weight

artículo científico publicado en 2007

Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people.

artículo científico publicado en 2008

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

artículo científico publicado en 2008

Predictors of Extraordinary Survival in the Iowa Established Populations for Epidemiologic Study of the Elderly: Cohort Follow-Up to “Extinction” ⬇️

artículo científico publicado el 7 de junio de 2011

Prevalence and distribution of hip and knee joint replacements and hip implants in older Americans by the end of life

artículo científico publicado en 2003

Problem behavior in the last year of life: prevalence, risks, and care receipt in older Americans

artículo científico publicado en 2001

Profile of disability in elderly people: estimates from a longitudinal population study.

artículo científico publicado en 1999

Proton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patients.

artículo científico publicado en 2017

Proton-Pump Inhibitors and Long-Term Risk of Community-Acquired Pneumonia in Older Adults

artículo científico publicado en 2018

Psychosis in the community and in prisons: a report from the British National Survey of psychiatric morbidity

artículo científico publicado en 2005

Racial disparities in receipt of hip and knee joint replacements are not explained by need: the Health and Retirement Study 1998-2004.

artículo científico publicado en 2008

Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

artículo científico publicado en 2017

Red cell distribution width and common disease onsets in 240,477 healthy volunteers followed for up to 9 years

artículo científico publicado en 2018

Reductions in disability prevalence among the highest income groups of older Brazilians

article

Regulatory options for pharmacogenetics

Relationship Between Urinary Nitrate Excretion and Blood Pressure in the InChianti Cohort.

artículo científico publicado en 2017

Reply

article published in 2007

Reply to WG Thompson.

artículo científico publicado en 2017

Report from the second cytomegalovirus and immunosenescence workshop

artículo científico publicado en 2011

Response letter to Shil and colleagues.

artículo científico publicado en 2013

Responsiveness of the index of mobility limitation: comparison with gait speed alone in the longitudinal aging study amsterdam

artículo científico publicado en 2003

Retirement and mental health: analysis of the Australian national survey of mental health and well-being

artículo científico publicado en 2005

Safety and Effectiveness of Statins for Prevention of Recurrent Myocardial Infarction in 12 156 Typical Older Patients: A Quasi-Experimental Study

artículo científico publicado en 2016

Self reported receipt of care consistent with 32 quality indicators: national population survey of adults aged 50 or more in England

artículo científico publicado en 2008

Self-reported quality of care for older adults from 2004 to 2011: a cohort study ⬇️

artículo científico publicado en 2014

Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in the United States

artículo científico publicado en 2011

Serum leptin and risk of cognitive decline in elderly italians.

artículo científico publicado en 2015

Severe mental illness in prisoners: a persistent problem that needs a concerted and long term response

artículo científico publicado en 1998

Sex differences in the prevalence of mobility disability in old age:the dynamics of incidence, recovery, and mortality

article

Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.

artículo científico publicado en 2017

Smoking cessation and transition into retirement: analyses from the English Longitudinal Study of Ageing

artículo científico publicado en 2007

Social inequalities and the common mental disorders: a systematic review of the evidence

artículo científico publicado en 2003

Social position and the common mental disorders with disability: estimates from the National Psychiatric Survey of Great Britain

artículo científico publicado en 2003

Socio-demographic correlates of mobility disability in older Brazilians: results of the first national survey

article

Socioeconomic status and the expectation of disability in old age: estimates for England

artículo científico publicado en 2000

Splicing factor 3B1 hypomethylation is associated with altered SF3B1 transcript expression in older humans

artículo científico publicado en 2014

Systematic identification of trans eQTLs as putative drivers of known disease associations

artículo científico publicado en 2013

The 9p21 myocardial infarction risk allele increases risk of peripheral artery disease in older people

artículo científico publicado en 2009

The European IVD Directive and Genetic Testing

article published in 2010

The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research

artículo científico publicado en 2021

The VEGFA165b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease

artículo científico publicado en 2018

The apolipoprotein E e4 polymorphism is strongly associated with poor mobility performance test results but not self-reported limitation in older people

artículo científico publicado en 2005

The coronary artery disease-associated 9p21 variant and later life 20-year survival to cohort extinction

artículo científico publicado en 2011

The current landscape for direct-to-consumer genetic testing: legal, ethical, and policy issues

artículo científico publicado en 2008

The distribution of the common mental disorders: social inequalities in Europe

artículo científico publicado en 2005

The dynamics of quality: a national panel study of evidence-based standards ⬇️

artículo científico publicado en 2015

The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians

artículo científico publicado en 2006

The genetics of human ageing

scientific article published on 05 November 2019

The mental health of early retirees-- national interview survey in Britain

artículo científico publicado en 2005

The outcome of targeting community mental health services: evidence from the West Lambeth schizophrenia cohort

artículo científico publicado en 1994

The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or INCHIANTI studies

artículo científico publicado en 2009

The predictive validity for mortality of the index of mobility-related limitation--results from the EPESE study

artículo científico publicado en 2003

The role of waist circumference in predicting disability in periretirement age adults

artículo científico publicado en 2006

The transcriptional landscape of age in human peripheral blood

artículo científico publicado en 2015

The value of England and Wales congenital malformation notification scheme data for epidemiology: male genital tract malformations

artículo científico publicado en 1988

Towards a gene expression biomarker set for human biological age.

artículo científico publicado en 2013

Trends in service use and treatment for mental disorders in adults throughout Great Britain

artículo científico publicado en 2004

Uric acid measurement improves prediction of cardiovascular mortality in later life.

artículo científico publicado en 2013

Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women

artículo científico publicado en 2012

Urinary bisphenol a concentration and angiography-defined coronary artery stenosis

artículo científico publicado en 2012

Variation in Thresholds for Reporting Mobility Disability Between National Population Subgroups and Studies

article

Variation in prescribing of hypnotics, anxiolytics and antidepressants between 61 general practices.

artículo científico publicado en 1995

Vitamin D and Risk of Cognitive Decline in Elderly Persons

Vitamin D and cognitive function

artículo científico

Vitamin D and cognitive impairment in the elderly U.S. population.

artículo científico publicado en 2010

Vitamin D and risk of cognitive decline in elderly persons

artículo científico publicado en 2010

WHAT BECOMES OF PEOPLE WITH DEMENTIA REFERRED TO COMMUNITY PSYCHOGERIATRIC TEAMS?

scholarly article by SUSAN BEDFORD et al published December 1996 in International Journal of Geriatric Psychiatry

Was John Reid right? Smoking, class, and pleasure: a population-based cohort study in England.

artículo científico publicado en 2007

What Level of Alcohol Consumption Is Hazardous for Older People? Functioning and Mortality in U.S. and English National Cohorts

article

What determines access to medium secure psychiatric provision?

Whole blood gene expression and interleukin-6 levels

artículo científico publicado en 2014

Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes

artículo científico publicado en 2014

[Disability among elderly women in Brazil]

artículo científico publicado en 2005

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