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Lista de obras de Raffaella Giavazzi

45th annual meeting of the Italian Cancer Society. Bergamo, 9-12 November 2003.

artículo científico publicado en 2004

A comparative analysis of oncofetal fibronectin and tenascin-C incorporation in tumour vessels using human recombinant SIP format antibodies

article

A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6

artículo científico publicado en 2012

A human acute lymphoblastic leukemia line with the T(4;11) translocation as a model of minimal residual disease in SCID mice

artículo científico publicado en 1997

A ligand-free, soluble urokinase receptor is present in the ascitic fluid from patients with ovarian cancer.

artículo científico publicado en 1993

A murine ovarian tumor with unique metastasizing capacity

artículo científico publicado en 1981

A proteomic approach for the identification of vascular markers of liver metastasis

artículo científico publicado en 2009

Activation of the SDF1/CXCR4 pathway retards muscle atrophy during cancer cachexia.

artículo científico publicado en 2016

An HSP90-mimic peptide revealed by fingerprinting the pool of antibodies from ovarian cancer patients

artículo científico publicado en 2004

An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency

artículo científico publicado en 1991

Angiogenesis inhibitors: implications for combination with conventional therapies

scientific article published on January 2010

Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development

artículo científico publicado en 2006

Antiangiogenic activity of aplidine, a new agent of marine origin

artículo científico publicado en 2004

Antiangiogenic activity of trabectedin in myxoid liposarcoma: Involvement of host TIMP-1 and TIMP-2 and tumor thrombospondin-1

artículo científico publicado en 2014

Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative

artículo científico publicado en 2002

Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator

artículo científico publicado en 2004

Anticancer therapy with angiogenesis inhibitors.

artículo científico publicado en 2001

Antiproliferative properties of flavone acetic acid (NSC 347512) (LM 975), a new anticancer agent

artículo científico publicado en 1987

Antitumor activity of taxol (NSC-125973) in human ovarian carcinomas growing in the peritoneal cavity of nude mice

artículo científico publicado en 1993

Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4.

artículo científico publicado en 2003

Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma xenografts

artículo científico publicado el 1 de abril de 1998

Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response.

artículo científico publicado en 2015

Bioavailability of VEGF in tumor-shed vesicles depends on vesicle burst induced by acidic pH.

artículo científico publicado en 2006

Blood coagulation changes in nude mice bearing human colon carcinomas

scientific article published on 01 January 1992

Cediranib combined with chemotherapy reduces tumor dissemination and prolongs the survival of mice bearing patient-derived ovarian cancer xenografts with different responsiveness to cisplatin.

artículo científico publicado en 2015

Characterization of novel clonal murine endothelial cell lines with an extended life span

artículo científico publicado en 2000

Characterization of tumor lines derived from spontaneous metastases of a transplanted murine sarcoma

scientific article published on 01 January 1981

Chemotherapy counteracts metastatic dissemination induced by antiangiogenic treatment in mice

artículo científico publicado en 2013

Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy

artículo científico publicado en 2005

Cisplatin plus paclitaxel and maintenance of bevacizumab on tumour progression, dissemination, and survival of ovarian carcinoma xenograft models

artículo científico publicado en 2012

Combination therapy in cancer: effects of angiogenesis inhibitors on drug pharmacokinetics and pharmacodynamics

artículo científico publicado en 2016

Comparative analysis of the membrane proteome of closely related metastatic and nonmetastatic tumor cells

artículo científico publicado en 2009

Comparative study on the metastatic behavior of human tumors in nude, beige/nude/xid and severe combined immunodeficient mice

scientific article published on 01 January 1993

Comparison of paclitaxel and docetaxel activity on human ovarian carcinoma xenografts

scientific article published on 01 January 1994

Contribution of tumor endothelial cells to drug resistance: anti-angiogenic tyrosine kinase inhibitors act as p-glycoprotein antagonists.

artículo científico publicado en 2017

Correction: Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle

artículo científico publicado en 2016

Correlation between the in vitro interaction of tumor cells with an organ environment and metastatic behavior in vivo

scientific article published on 01 January 1987

Correlation of Tumor Growth Inhibitory Activity of Macrophages Exposed to Adriamycin and Adriamycin Sensitivity of the Target Tumor Cells234

artículo científico publicado en 1984

Cytokine-mediated tumor-endothelial cell interaction in metastasis

artículo científico publicado en 1996

Cytokines and cell adhesion molecules in tumor-endothelial cell interaction and metastasis.

artículo científico publicado en 1994

Determination of paclitaxel distribution in solid tumors by nano-particle assisted laser desorption ionization mass spectrometry imaging

artículo científico publicado en 2013

Differential expression of a sialoglycoprotein with an approximate molecular weight of 900,000 on metastatic human colon carcinoma cells growing in culture and in tumor tissues

artículo científico publicado en 1988

Differential vascular expression and regulation of oncofetal tenascin-C and fibronectin variants in renal cell carcinoma (RCC): implications for an individualized angiogenesis-related targeted drug delivery

artículo científico publicado en 2011

Distinct role of fibroblast growth factor-2 and vascular endothelial growth factor on tumor growth and angiogenesis

artículo científico publicado en 2003

Distribution of mono-, di, and tri-O-acetylated sialic acids in normal and neoplastic colon.

artículo científico publicado en 1988

Divergent effects of macrophage toxins on growth of primary tumors and lung metastases in mice

artículo científico publicado en 1980

Driving p53 response to Bax activation greatly enhances sensitivity to taxol by inducing massive apoptosis.

artículo científico publicado en 2000

Dual targeting of tumor and endothelial cells by gonadotropin-releasing hormone agonists to reduce melanoma angiogenesis

artículo científico publicado en 2010

E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models

artículo científico publicado en 2011

Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts

artículo científico publicado en 1998

Effect of Interleukin-1-beta on Metastasis Formation in Different Tumor Systems

artículo científico publicado en 1991

Effect of alltrans-retinoic acid (ATRA) on the adhesive and motility properties of acute promyelocytic leukemia cells

artículo científico publicado en 1997

Endothelial cell migration and invasiveness are induced by a soluble factor produced by murine endothelioma cells transformed by polyoma virus middle T oncogene

artículo científico publicado en 1993

Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

artículo científico publicado en 2000

Enhancement of Metastatic Potential of Murine and Human Melanoma Cells by Laminin Receptor Peptide G: Attachment of Cancer Cells to Subendothelial Matrix as a Pathway for Hematogenous Metastasis

artículo científico publicado en 1993

Establishment of human acute myelogenous leukemia lines secreting interleukin-1β in SCID mice

artículo científico publicado en 1995

Experimental nude mouse model of human colorectal cancer liver metastases

artículo científico publicado en 1986

Expression levels of vascular endothelial growth factor, matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinases 1 and 2 in the plasma of patients with ovarian carcinoma

scientific article published on 01 September 2003

Expression of beta-tubulin isotypes in human ovarian carcinoma xenografts and in a sub-panel of human cancer cell lines from the NCI-Anticancer Drug Screen: correlation with sensitivity to microtubule active agents

artículo científico publicado en 2001

Expression of cell surface P-glycoprotein by an adriamycin-resistant murine fibrosarcoma.

artículo científico publicado en 1984

Expression of the 67 kD laminin receptor in human ovarian carcinomas as defined by a monoclonal antibody, MLuC5.

artículo científico publicado en 1996

Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression.

artículo científico publicado en 2011

Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain

artículo científico publicado en 2008

Flavone acetic acid pharmacokinetics in nude mice

artículo científico publicado en 1990

Gemtuzumab ozogamicin (Mylotarg) has therapeutic activity against CD33 acute lymphoblastic leukaemias in vitro and in vivo.

artículo científico publicado en 2005

Gene expression correlating with response to paclitaxel in ovarian carcinoma xenografts

article

Glycerophosphoinositols inhibit the ability of tumour cells to invade the extracellular matrix

artículo científico publicado en 2005

Growth advantage and vascularization induced by basic fibroblast growth factor overexpression in endometrial HEC-1-B cells: an export-dependent mechanism of action.

artículo científico publicado en 1995

Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice.

artículo científico publicado en 1986

Growth and metastatic behavior of human tumor cells implanted into nude and beige nude mice

artículo científico publicado en 1987

Growth potential of human colorectal carcinomas in nude mice: association with the preoperative serum concentration of carcinoembryonic antigen in patients

artículo científico publicado en 1988

Heterogeneity of paclitaxel distribution in different tumor models assessed by MALDI mass spectrometry imaging

artículo científico publicado en 2016

High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer

artículo científico publicado en 1999

Human immunodeficiency virus-1 (HIV-1)-Tat protein promotes migration of acquired immunodeficiency syndrome-related lymphoma cells and enhances their adhesion to endothelial cells

artículo científico publicado en 1999

IDN 5390: a new concept in taxane development

artículo científico publicado en 2003

IDN5109, a taxane with oral bioavailability and potent antitumor activity.

artículo científico publicado en 2000

IL-1alpha gene-transfected human melanoma cells increase tumor-cell adhesion to endothelial cells and their retention in the lung of nude mice

artículo científico publicado en 1996

Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells

artículo científico publicado en 2008

Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium

artículo científico publicado en 2008

Identification of thrombin-like activity in ovarian cancer associated ascites and modulation of multiple cytokine networks

artículo científico publicado en 2011

Impact of VEGF-dependent tumour micro-environment on EDB fibronectin expression by subcutaneous human tumour xenografts in nude mice

artículo científico publicado en 2009

In vivo measurement of vascular modulation in experimental tumors using a fluorescent contrast agent

artículo científico publicado en 2008

In vivo protein biotinylation for identification of organ-specific antigens accessible from the vasculature

artículo científico publicado en 2005

Inactivating STAT3: bad for tumor, good for muscle

artículo científico publicado en 2015

Inhibition of Angiogenesis and Murine Hemangioma Growth by Batimastat, a Synthetic Inhibitor of Matrix Metalloproteinases

artículo científico publicado en 1995

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

artículo científico publicado en 2012

Inhibition of matrix metalloproteinases by over‐expression of tissue inhibitor of metalloproteinase‐2 inhibits the growth of experimental hemangiomas

artículo científico publicado en 2001

Inhibition of the metastatic spread and growth of B16-BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor

artículo científico publicado en 1994

Interleukin 1 receptor antagonist inhibits the augmentation of metastasis induced by interleukin 1 or lipopolysaccharide in a human melanoma/nude mouse system.

artículo científico publicado en 1993

Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice

artículo científico publicado en 1990

Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α.

artículo científico publicado en 2010

Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy

artículo científico publicado en 1989

Intratumor heterogeneity and its impact on drug distribution and sensitivity

artículo científico

Isolation and characterization of human tumor-derived capillary endothelial cells: role of oncofetal fibronectin

artículo científico publicado en 1998

Isolation and preliminary characterization of an Adriamycin-resistant murine fibrosarcoma cell line.

artículo científico publicado en 1983

Laminin inhibits the adhesion of a murine tumor of macrophage origin

scientific article published on 01 August 1982

Malignant behavior and resistance to cisplatin of human ovarian carcinoma xenografts established from the same patient at different stages of the disease.

artículo científico publicado en 1991

Matrix metalloproteinase inhibition: a review of anti-tumour activity

artículo científico publicado en 1995

Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation.

artículo científico publicado en 2003

Membrane fluidity affects tumor-cell motility, invasion and lung-colonizing potential

artículo científico publicado en 1989

Mesothelial cells induce the motility of human ovarian carcinoma cells

artículo científico publicado en 1999

Metabolism of tumour-derived urokinase receptor and receptor fragments in cancer patients and xenografted mice.

artículo científico publicado en 2004

Metastasizing capacity of tumour cells from spontaneous metastases of transplanted murine tumours

artículo científico publicado en 1980

Metastatic behavior of an adriamycin-resistant murine tumor

artículo científico publicado en 1983

Metastatic potential of metastases, tumor cell heterogeneity, and therapeutic implications.

artículo científico publicado en 1982

Modulation of tumor angiogenesis by conditional expression of fibroblast growth factor-2 affects early but not established tumors.

artículo científico publicado en 2001

Molecular characterisation of a panel of human ovarian carcinoma xenografts

artículo científico publicado en 1998

Mononuclear phagocyte adherence in the presence of laminin. A possible marker of cellular differentiation

artículo científico publicado en 1983

Natural cytotoxic activity in human lungs

artículo científico publicado en 1982

Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds

artículo científico publicado en 2010

Organ distribution of experimental metastases of a human colorectal carcinoma injected in nude mice

artículo científico publicado en 1989

Organ-specific growth of a murine lymphoma of spontaneous origin in nude mice

artículo científico publicado en 1991

Orthotopic Model of Ovarian Cancer

artículo científico publicado en 2016

Outbreaks of hyperkeratotic dermatitis of athymic nude mice in northern Italy

artículo científico publicado en 1997

PO-15 - Antiangiogenic small molecule ligands of FGF2 derived from the endogenous inhibitor thrombospondin-1.

artículo científico publicado en 2016

PO-44 - Tissue factor pathway inhibitor-2 (TFPI-2) is cleaved by PRSS3: implication for tumor endothelial cells migration.

artículo científico publicado en 2016

Paclitaxel (Taxol(R)) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells

artículo científico publicado en 1996

Paclitaxel enhances therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin-positive metastatic human melanoma xenografts

artículo científico publicado en 2012

Patient-Derived Ovarian Tumor Xenografts Recapitulate Human Clinicopathology and Genetic Alterations

artículo científico publicado en 2014

Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib.

artículo científico publicado en 2013

Phenotypic and functional characteristics of tumour-derived microvascular endothelial cells

artículo científico publicado en 1999

Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.

artículo científico publicado en 1990

Posttranscriptional stimulation of endothelial cell matrix metalloproteinases 2 and 1 by endothelioma cells.

artículo científico publicado en 2000

Potential antagonism of tubulin-binding anticancer agents in combination therapies.

artículo científico publicado en 2005

Preclinical development of metalloproteasis inhibitors in cancer therapy.

artículo científico publicado en 2001

Procoagulant activity of sarcoma sublines with different metastatic potential

artículo científico publicado en 1981

Prostaglandin and thromboxane synthesis by M5076 ovarian reticulosarcoma during growth: effects of a thromboxane synthetase inhibitor

artículo científico publicado en 1987

Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype

artículo científico publicado en 2009

Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment

artículo científico publicado en 2011

Response to flavone acetic acid (NSC 347512) of primary and metastatic human colorectal carcinoma xenografts

artículo científico publicado el 1 de marzo de 1988

Retention of vital dyes correlates inversely with the multidrug-resistant phenotype of adriamycin-selected murine fibrosarcoma variants

artículo científico publicado en 1990

Retroviral vector-mediated gene transfer into human primary myogenic cells leads to expression in muscle fibers in vivo

artículo científico publicado en 1993

Role of beta 1 integrins in tumor cell adhesion to cultured human endothelial cells

scientific article published on 01 November 1991

Sequence dependent antitumour efficacy of the vascular disrupting agent ZD6126 in combination with paclitaxel.

artículo científico publicado en 2007

Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells

artículo científico publicado en 2002

Small molecules in anti-angiogenic therapy.

artículo científico publicado en 2002

Soluble intercellular adhesion molecule 1 is released by human melanoma cells and is associated with tumor growth in nude mice

artículo científico publicado en 1992

Soluble intercellular adhesion molecule—1 (ICAM-1) is released into the serum and ascites of human ovarian carcinoma patients and in nude mice bearing tumour xenografts

scientific article published on 01 January 1994

Soluble stroma-related biomarkers of pancreatic cancer.

artículo científico publicado en 2018

Solution state conformation and degradation of cyclopeptides containing an NGR motif

artículo científico publicado en 2005

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle.

artículo científico publicado en 2015

Syngeneic Murine Metastasis Models: B16 Melanoma

artículo científico publicado en 2001

Syngeneic Murine Metastasis Models: B16 Melanoma

artículo científico publicado en 2014

Targeting angiogenesis with compounds from the extracellular matrix

artículo científico

The 140-kilodalton antiangiogenic fragment of thrombospondin-1 binds to basic fibroblast growth factor

scientific article published on 01 April 1997

The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling

artículo científico publicado en 2011

The biological basis for antiangiogenic therapy

artículo científico publicado en 2000

The combination of the tyrosine kinase receptor inhibitor SU6668 with paclitaxel affects ascites formation and tumor spread in ovarian carcinoma xenografts growing orthotopically

artículo científico publicado en 2003

The combination of yondelis and cisplatin is synergistic against human tumor xenografts

artículo científico publicado en 2003

The effects of vandetanib on paclitaxel tumor distribution and antitumor activity in a xenograft model of human ovarian carcinoma

artículo científico publicado en 2009

The heparin binding 25 kDa fragment of thrombospondin-1 promotes angiogenesis and modulates gelatinase and TIMP-2 production in endothelial cells

artículo científico publicado en 2000

The immunocytokine F8-IL2 improves the therapeutic performance of sunitinib in a mouse model of renal cell carcinoma

artículo científico publicado en 2010

The metalloproteinase inhibitor batimastat (BB-94) causes cell cycle phase perturbations in ovarian cancer cells

artículo científico publicado en 1999

The tyrosine kinase inhibitor E-3810 combined with paclitaxel inhibits the growth of advanced-stage triple-negative breast cancer xenografts

artículo científico publicado en 2012

The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis

artículo científico publicado en 2006

Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2

scientific article published on 28 August 2003

Thrombospondin induces glomerular mesangial cell adhesion and migration

artículo científico publicado en 1992

Thrombospondin modulates basic fibroblast growth factor activities on endothelial cells

artículo científico publicado el 1 de enero de 1992

Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions

artículo científico publicado en 1999

Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2.

artículo científico publicado en 2014

Thrombospondin-1/HIV-1 Tat protein interaction: modulation of the biological activity of extracellular Tat

article

Transfer of the ADA gene into human ADA-deficient T lymphocytes reconstitutes specific immune functions

artículo científico publicado en 1992

Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation

artículo científico publicado en 1995

Trypsinogen 4 boosts tumor endothelial cells migration through proteolysis of tissue factor pathway inhibitor-2.

artículo científico publicado en 2015

Tumor delivery of chemotherapy combined with inhibitors of angiogenesis and vascular targeting agents

artículo científico

Tumor progression and metastatic dissemination in ovarian cancer after dose-dense or conventional paclitaxel and cisplatin plus bevacizumab

artículo científico publicado en 2018

Tumor-derived suppressor factors (TDSFs) in normal and neoplastic colon and rectum

artículo científico publicado en 1986

Tumor-host interaction in the optimization of paclitaxel-based combination therapies with vascular targeting compounds

artículo científico publicado en 2007

Tumour levels of O6-alkylguanine-DNA-alkyltransferase and sensitivity to BCNU of human xenografts.

artículo científico publicado en 1992

Tumour sublines with different metastatic capacity induce similar blood coagulation changes in the host

artículo científico publicado en 1981

Vascular disrupting activity of tubulin-binding 1,5-diaryl-1H-imidazoles

artículo científico publicado en 2009

Vascular endothelial growth factor c promotes ovarian carcinoma progression through paracrine and autocrine mechanisms.

artículo científico publicado en 2014

Vascular endothelial growth factor stimulates organ-specific host matrix metalloproteinase-9 expression and ovarian cancer invasion

artículo científico publicado en 2008

Vascular endothelium summary statement III: Cancer prevention and control

artículo científico publicado en 2006

Vascular-targeting activity of ZD6126, a novel tubulin-binding agent.

artículo científico publicado en 2003

p73 overexpression increases VEGF and reduces thrombospondin-1 production: implications for tumor angiogenesis

artículo científico publicado en 2001