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Lista de obras de Nobuya Inagaki

A Large Difference in Dose Timing of Basal Insulin Introduces Risk of Hypoglycemia and Overweight: A Cross-Sectional Study

artículo científico publicado en 2017

A comparative analysis of intraperitoneal versus intracerebroventricular administration of bromodeoxyuridine for the study of cell proliferation in the adult rat brain

artículo científico publicado en 2011

A comparison between 11C-methionine PET/CT and MIBI SPECT/CT for localization of parathyroid adenomas/hyperplasia

artículo científico publicado en 2015

A hospital-based cross-sectional study to develop an estimation formula for 2-h post-challenge plasma glucose for screening impaired glucose tolerance

artículo científico publicado en 2013

A new equation to estimate basal energy expenditure of patients with diabetes.

artículo científico publicado en 2012

A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice

artículo científico publicado en 2007

A randomized dose-finding study demonstrating the efficacy and tolerability of albiglutide in Japanese patients with type 2 diabetes mellitus

artículo científico publicado en 2014

A real-time method of imaging glucose uptake in single, living mammalian cells.

artículo científico publicado en 2007

A simulation study on the constancy of cardiac energy metabolites during workload transition.

artículo científico publicado en 2016

A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement

artículo científico publicado en 2006

A variant form of laminin is responsible for the neurite outgrowth-promoting activity in conditioned medium from a squamous carcinoma cell line

artículo científico publicado en 1993

ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug

artículo científico publicado en 2009

ABCA2 deficiency results in abnormal sphingolipid metabolism in mouse brain

artículo científico publicado en 2007

ABCA3 as a Lipid Transporter in Pulmonary Surfactant Biogenesis

scientific article published in Journal of Biological Chemistry

ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells

artículo científico publicado en 2001

ABCA3-mediated choline-phospholipids uptake into intracellular vesicles in A549 cells.

artículo científico publicado en 2007

ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination

artículo científico publicado en 2002

Aberrant catalytic cycle and impaired lipid transport into intracellular vesicles in ABCA3 mutants associated with nonfatal pediatric interstitial lung disease

artículo científico publicado en 2008

Abnormalities of pancreatic islets by targeted expression of a dominant-negative K ATP channel ⬇️

artículo científico publicado el 28 de octubre de 1997

Adiposity induced by interleukin-17A blockade

artículo científico publicado en 2016

Adult pancreatic islets require differential pax6 gene dosage

article

Advancements in Transplantation Therapy for Diabetes - Pancreas, Islet and Stem Cell

artículo científico publicado en 2020

Analysis of factors influencing pancreatic beta-cell function in Japanese patients with type 2 diabetes: association with body mass index and duration of diabetic exposure.

artículo científico publicado en 2008

Analysis of factors influencing postprandial C-peptide levels in Japanese patients with type 2 diabetes: Comparison with C-peptide levels after glucagon load

artículo científico publicado en 2011

Assessment of a New Piezoelectric Transducer Sensor for Noninvasive Cardiorespiratory Monitoring of Newborn Infants in the NICU

artículo científico publicado en 2010

Association of Glucagon-like Peptide-1 Receptor (GLP-1R)-targeted Imaging Probe with In-vivo GLP-1R Agonist Glucose-lowering Effects

artículo científico publicado en 2020

Association of serum resistin with TNF system activity in Japanese type 2 diabetic patients

Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice

scientific article published on 19 January 2017

Attitudes of patients and physicians to insulin therapy in Japan: an analysis of the Global Attitude of Patients and Physicians in Insulin Therapy study

artículo científico publicado en 2016

BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis

scientific journal article

BK channels reveal novel phosphate sensitivity in SNr neurons

artículo científico publicado en 2012

Basal Plasma Aldosterone Concentration Predicts Therapeutic Outcomes in Primary Aldosteronism

artículo científico publicado en 2020

Beneficial Effects of Exendin-4 on Experimental Polyneuropathy in Diabetic Mice ⬇️

artículo científico publicado el 1 de agosto de 2011

Beta-cell replacement strategies for diabetes

artículo científico publicado en 2017

Brain-specific natriuretic peptide receptor-B deletion attenuates high-fat diet-induced visceral and hepatic lipid deposition in mice

artículo científico publicado en 2016

Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitors: A report of five cases

artículo científico publicado en 2017

Bullous pemphigoid with dipeptidyl peptidase-4 inhibitors: Clinical features and pathophysiology

artículo científico publicado en 2019

C-type natriuretic peptide restores impaired skeletal growth in a murine model of glucocorticoid-induced growth retardation

article

Carbohydrate intake is associated with time spent in the euglycemic range in patients with type 1 diabetes.

artículo científico publicado en 2015

Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001-2010: report of Committee on Causes of Death in Diabetes Mellitus.

artículo científico publicado en 2017

Ceritinib-associated hyperglycemia in the Japanese Adverse Drug Event Report Database

artículo científico publicado en 2019

Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency.

artículo científico publicado en 2006

Chronic Reduction of GIP Secretion Alleviates Obesity and Insulin Resistance Under High-Fat Diet Conditions

artículo científico publicado en 2014

Chronic administration of apple polyphenols ameliorates hyperglycaemia in high-normal and borderline subjects: A randomised, placebo-controlled trial

artículo científico publicado en 2017

Circadian rhythms and diabetes.

artículo científico publicado en 2011

Cl- channel blockers inhibit transition of quiescent (G0) fibroblasts into the cell cycle

artículo científico publicado en 2003

Clinical and functional characterization of the Pro1198Leu ABCC8 gene mutation associated with permanent neonatal diabetes mellitus

artículo científico publicado en 2013

Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart

artículo científico publicado en 1995

Cloning and pharmacological characterization of a fourth P2X receptor subtype widely expressed in brain and peripheral tissues including various endocrine tissues.

artículo científico publicado en 1996

Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2

artículo científico publicado en 1995

Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism

scientific journal article

Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2

scientific article published in 2000

Cluster-randomized trial to improve the quality of diabetes management: The study for the efficacy assessment of the standard diabetes manual (SEAS-DM).

artículo científico publicado en 2016

Color record in self-monitoring of blood glucose improves glycemic control by better self-management

artículo científico publicado en 2014

Comparison of incretin immunoassays with or without plasma extraction: Incretin secretion in Japanese patients with type 2 diabetes

artículo científico publicado en 2012

Control of intestinal stem cell fate: A novel approach to treating diabetes

artículo científico publicado en 2015

Curcumin inhibits glucose production in isolated mice hepatocytes

artículo científico publicado en 2008

DEPTOR-related mTOR suppression is involved in metformin's anti-cancer action in human liver cancer cells

artículo científico

Deacetylation of phosphoglycerate mutase in its distinct central region by SIRT2 down-regulates its enzymatic activity

artículo científico publicado en 2014

Development of 111In-labeled exendin(9-39) derivatives for single-photon emission computed tomography imaging of insulinoma

artículo científico publicado en 2017

Development of novel cell lines of diabetic dysfunction model fit for cell-based screening tests of medicinal materials

artículo científico publicado en 2012

Dietary corosolic acid ameliorates obesity and hepatic steatosis in KK-Ay mice

artículo científico publicado en 2008

Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets

artículo científico publicado en 2006

Disruption of Kir6.2-containing ATP-sensitive potassium channels impairs maintenance of hypoxic gasping in mice

artículo científico publicado en 2007

Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity

artículo científico publicado en 2010

Distribution and hormonal characterization of primary murine L cells throughout the gastrointestinal tract.

artículo científico publicado en 2017

Dysregulated glycolysis as an oncogenic event

artículo científico publicado en 2015

Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

artículo científico publicado en 2014

Effect of corosolic acid on gluconeogenesis in rat liver

artículo científico publicado en 2008

Effect of nutritional counseling and long term isomaltulose based liquid formula (MHN-01) intake on metabolic syndrome.

artículo científico publicado en 2015

Effect of vitamin D on gastrin and gastric somatostatin secretion from the isolated perfused rat stomach

artículo científico publicado en 1988

Effects of Baseline Blood Pressure and Low-Density Lipoprotein Cholesterol on Safety and Efficacy of Canagliflozin in Japanese Patients with Type 2 Diabetes Mellitus.

artículo científico publicado en 2015

Effects of glucose and meal ingestion on incretin secretion in Japanese subjects with normal glucose tolerance

artículo científico publicado en 2012

Effects of long-term dipeptidyl peptidase-IV inhibition on body composition and glucose tolerance in high fat diet-fed mice

artículo científico publicado en 2009

Effects of non-statin antilipemic drugs on vascular endothelial function in patients with type 2 diabetes with hypercholesterolemia

Effects of pretransplant sarcopenia and sequential changes in sarcopenic parameters after living donor liver transplantation

artículo científico publicado en 2016

Effects of structured testing versus routine testing of blood glucose in diabetes self-management: A randomized controlled trial

artículo científico publicado en 2016

Effects of thorough mastication on postprandial plasma glucose concentrations in nonobese Japanese subjects

artículo científico publicado en 2005

Efficacy and Safety of Lixisenatide in Japanese Patients with Type 2 Diabetes Insufficiently Controlled with Basal Insulin±Sulfonylurea: A Subanalysis of the GetGoal-L-Asia Study

artículo científico publicado en 2015

Efficacy and Safety of the SGLT2 Inhibitor Luseogliflozin in Japanese Patients With Type 2 Diabetes Mellitus Stratified According to Baseline Body Mass Index: Pooled Analysis of Data From 52-Week Phase III Trials.

artículo científico publicado en 2016

Efficacy and safety of canagliflozin alone or as add-on to other oral antihyperglycemic drugs in Japanese patients with type 2 diabetes: A 52-week open-label study.

artículo científico publicado en 2014

Efficacy and safety of canagliflozin as add-on therapy to teneligliptin in Japanese patients with type 2 diabetes mellitus: Results of a 24-week, randomized, double-blind, placebo-controlled trial

artículo científico publicado en 2017

Efficacy and safety of canagliflozin in Japanese patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, 12-week study

scientific article published on 14 July 2013

Efficacy and safety of canagliflozin in combination with insulin: a double-blind, randomized, placebo-controlled study in Japanese patients with type 2 diabetes mellitus

artículo científico publicado en 2016

Efficacy and safety of canagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled with diet and exercise: a 24-week, randomized, double-blind, placebo-controlled, Phase III study

artículo científico publicado en 2014

Efficacy and safety of empagliflozin monotherapy for 52 weeks in Japanese patients with type 2 diabetes: a randomized, double-blind, parallel-group study

artículo científico publicado en 2015

Efficacy and safety of linagliptin in type 2 diabetes patients with self-reported hepatic disorders: A retrospective pooled analysis of 17 randomized, double-blind, placebo-controlled clinical trials

artículo científico publicado en 2016

Efficacy and safety of luseogliflozin added to various oral antidiabetic drugs in Japanese patients with type 2 diabetes mellitus

artículo científico publicado en 2015

Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study.

artículo científico publicado en 2015

Efficacy and safety of once-weekly oral trelagliptin switched from once-daily dipeptidyl peptidase-4 inhibitor in patients with type 2 diabetes mellitus: An open-label, phase 3 exploratory study

artículo científico publicado en 2017

Efficacy and safety of switching from basal insulin to sitagliptin in Japanese type 2 diabetes patients

artículo científico publicado en 2012

Efficacy and safety profile of exenatide once weekly compared with insulin once daily in Japanese patients with type 2 diabetes treated with oral antidiabetes drug(s): results from a 26-week, randomized, open-label, parallel-group, multicenter, noni

artículo científico

Empagliflozin monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, 12-week, double-blind, placebo-controlled, phase II trial

artículo científico publicado en 2014

Enhanced vascular endothelial growth factor signaling in islets contributes to β cell injury and consequential diabetes in spontaneously diabetic Torii rats.

artículo científico publicado en 2014

Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice

artículo científico publicado en 2012

Enteral supplementation with glutamine, fiber, and oligosaccharide modulates incretin and glucagon-like peptide-2 secretion

artículo científico publicado en 2014

Epidemiology, clinical characteristics, and genetic etiology of neonatal diabetes in Japan

artículo científico publicado en 2017

Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia

artículo científico publicado en 2015

Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation

artículo científico publicado en 2010

Exendin-4 suppresses SRC activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner ⬇️

artículo científico publicado en 2010

Exome sequencing identifies a new candidate mutation for susceptibility to diabetes in a family with highly aggregated type 2 diabetes

artículo científico publicado en 2013

Expression of ABCA2 protein in both non-myelin-forming and myelin-forming Schwann cells in the rodent peripheral nerve

artículo científico publicado en 2006

Expression of wild-type, but not mutant, loricrin causes programmed cell death in HaCaT keratinocytes

artículo científico publicado en 2010

FGF-21 enhances islet engraftment in mouse syngeneic islet transplantation model

artículo científico publicado en 2010

Factors Affecting Canagliflozin-Induced Transient Urine Volume Increase in Patients with Type 2 Diabetes Mellitus

scientific article published on 15 December 2016

Factors responsible for age-related elevation in fasting plasma glucose: a cross-sectional study in Japanese men.

artículo científico publicado en 2008

Factors responsible for deteriorating glucose tolerance in newly diagnosed type 2 diabetes in Japanese men.

artículo científico publicado en 2006

Factors responsible for elevation of 1-h postchallenge plasma glucose levels in Japanese men.

artículo científico publicado en 2008

Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion

article by Kimitaka Shibue et al published 1 April 2015 in American Journal of Physiology - Endocrinology and Metabolism

Free fatty acid receptor GPR120 is highly expressed in enteroendocrine K cells of the upper small intestine and has a critical role in GIP secretion after fat ingestion

artículo científico publicado en 2014

Free fatty acid receptors, G protein-coupled receptor 120 and G protein-coupled receptor 40, are essential for oil-induced gastric inhibitory polypeptide secretion

artículo científico publicado en 2019

Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: Role of adenosine triphosphate-sensitive K(+) channels

artículo científico publicado en 2015

GCKR mutations in Japanese families with clustered type 2 diabetes

artículo científico publicado en 2010

GLP-1 receptor agonist attenuates endoplasmic reticulum stress-mediated β-cell damage in Akita mice

artículo científico publicado en 2011

GLP-1 receptor antagonist as a potential probe for pancreatic beta-cell imaging

artículo científico publicado en 2009

GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis

artículo científico publicado en 2008

GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells

artículo científico publicado en 2019

Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis

artículo científico publicado en 2006

Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changes

artículo científico publicado en 2007

Glucose sensitivity in mouse substantia nigra pars reticulata neurons in vitro

artículo científico publicado en 2004

Glucose-dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance, but deteriorated bone loss in ovariectomized mice

scientific article published on 27 December 2018

Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.

artículo científico publicado en 2013

Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion

artículo científico publicado en 2014

Glycemic instability in type 1 diabetic patients: Possible role of ketosis or ketoacidosis at onset of diabetes

artículo científico publicado en 2008

Glycemic variability is associated with quality of life and treatment satisfaction in patients with type 1 diabetes.

artículo científico publicado en 2015

Heterozygous ABCA3 mutation associated with non-fatal evolution of respiratory distress

artículo científico publicado en 2007

Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance

artículo científico publicado en 2017

Heterozygous RFX6 protein truncating variants cause Maturity-Onset Diabetes of the Young (MODY) with reduced penetrance

Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.

artículo científico publicado en 2010

High Prevalence of Diabetes in Patients With Primary Aldosteronism (PA) Associated With Subclinical Hypercortisolism and Prediabetes More Prevalent in Bilateral Than Unilateral PA: A Large, Multicenter Cohort Study in Japan

scientific article published on 01 May 2019

High prevalence of vitamin K and D deficiency and decreased BMD in inflammatory bowel disease

artículo científico publicado en 2008

Human ABCA3, a product of a responsible gene for abca3 for fatal surfactant deficiency in newborns, exhibits unique ATP hydrolysis activity and generates intracellular multilamellar vesicles.

artículo científico publicado en 2004

Identification and characterization of a novel ABCA3 mutation

artículo científico publicado en 2009

Immuno-localization of sulphonylurea receptor 1 in rat pancreas

artículo científico publicado en 1999

Impact of endogenous and exogenous insulin on basal energy expenditure in patients with type 2 diabetes under standard treatment

artículo científico publicado en 2011

Impact of quality as well as quantity of skeletal muscle on outcomes after liver transplantation

artículo científico publicado en 2014

Impaired adipogenic capacity in induced pluripotent stem cells from lipodystrophic patients with BSCL2 mutations

artículo científico publicado en 2016

Impaired metabolism-secretion coupling in pancreatic beta-cells: role of determinants of mitochondrial ATP production.

artículo científico publicado en 2007

Importance of contralateral aldosterone suppression during adrenal vein sampling in the subtype evaluation of primary aldosteronism

artículo científico publicado en 2015

Increase in liver glucose transporter mRNA levels during rat liver regeneration

artículo científico publicado en 1990

Increased Bone Turnover and Possible Accelerated Fracture Healing in a Murine Model With an Increased Circulating C-Type Natriuretic Peptide

artículo científico publicado en 2015

Influence of Renal Function on the 52-Week Efficacy and Safety of the Sodium Glucose Cotransporter 2 Inhibitor Luseogliflozin in Japanese Patients with Type 2 Diabetes Mellitus.

artículo científico publicado en 2015

Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion

artículo científico publicado en 2012

Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice

artículo científico publicado en 2008

Inhibition of Gastric Inhibitory Polypeptide Receptor Signaling in Adipose Tissue Reduces Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice

artículo científico publicado en 2017

Initiating SGLT2 inhibitor therapy to improve renal outcomes for persons with diabetes eligible for an intensified glucose-lowering regimen: hypothetical intervention using parametric g-formula modeling

artículo científico publicado en 2022

Insulin Secretory Defect and Insulin Resistance in Isolated Impaired Fasting Glucose and Isolated Impaired Glucose Tolerance.

artículo científico publicado en 2015

Insulin secretory capacity and insulin sensitivity in impaired fasting glucose in Japanese

artículo científico publicado en 2012

Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration

artículo científico publicado en 2008

Intracellular ATP-binding cassette transporter A3 is expressed in lung cancer cells and modulates susceptibility to cisplatin and paclitaxel

artículo científico publicado en 2013

Ionic mechanisms and Ca2+ dynamics underlying the glucose response of pancreatic β cells: a simulation study ⬇️

artículo científico publicado el 1 de julio de 2011

Is the concept of ‘cardiometabolic risk’ more useful than ‘metabolic syndrome’?

artículo científico publicado en 2007

KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state

artículo científico publicado en 2014

Kir2.2v: a possible negative regulator of the inwardly rectifying K+ channel Kir2.2

artículo científico publicado en 1996

Kir6.1: A Possible Subunit of ATP-Sensitive K+Channels in Mitochondria ⬇️

artículo científico publicado el 29 de diciembre de 1997

Lack of goal attainment regarding the low-density lipoprotein cholesterol level in the management of type 2 diabetes mellitus

artículo científico publicado en 2013

Lectin-like oxidized LDL receptor-1 (LOX-1) acts as a receptor for remnant-like lipoprotein particles (RLPs) and mediates RLP-induced migration of vascular smooth muscle cells

artículo científico publicado en 2008

Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet

article

Linagliptin monotherapy provides superior glycaemic control versus placebo or voglibose with comparable safety in Japanese patients with type 2 diabetes: a randomized, placebo and active comparator-controlled, double-blind study

scientific article published on 17 January 2012

Linagliptin provides effective, well-tolerated add-on therapy to pre-existing oral antidiabetic therapy over 1 year in Japanese patients with type 2 diabetes

artículo científico publicado en 2013

Lipopolysaccharide inhibits hepatic gluconeogenesis in rats: The role of immune cells

artículo científico publicado en 2017

Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls

artículo científico publicado en 2010

Localization of mouse mitochondrial SIRT proteins: shift of SIRT3 to nucleus by co-expression with SIRT5

scientific journal article

Long-term Effects of Mitiglinide in Japanese Diabetics Inadequately Controlled with DPP-4 Inhibitor or Biguanide Monotherapy

artículo científico publicado en 2014

Long-term effect of dipeptidyl peptidase-4 inhibition on β-cell mass in an advanced-aged diet-induced obesity mouse model

artículo científico publicado en 2014

Long-term efficacy and safety of canagliflozin in combination with insulin in Japanese patients with type 2 diabetes mellitus

artículo científico publicado en 2017

Long-term outcome of islet transplantation on insulin-dependent diabetes mellitus: An observational cohort study

scientific article published on 17 September 2019

Long-term safety and efficacy of a novel once-weekly oral trelagliptin as monotherapy or in combination with an existing oral antidiabetic drug in patients with type 2 diabetes mellitus: A 52-week open-label, phase 3 study

artículo científico publicado en 2016

Long-term safety and efficacy of exenatide twice daily in Japanese patients with suboptimally controlled type 2 diabetes

artículo científico publicado en 2011

Long-term safety of linagliptin monotherapy in Japanese patients with type 2 diabetes.

artículo científico publicado en 2012

Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis.

artículo científico publicado en 2012

M phase-specific expression and phosphorylation-dependent ubiquitination of the ClC-2 channel

artículo científico publicado en 2002

Mechanisms of fat-induced gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide secretion from K cells

artículo científico publicado en 2016

Metabolic syndrome, insulin resistance, and atherosclerosis in Japanese type 2 diabetic patients

artículo científico publicado en 2007

Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice

artículo científico publicado en 2010

Metformin: New Preparations and Nonglycemic Benefits

artículo científico publicado en 2017

MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1.

artículo científico publicado en 1997

Modulation of reconstituted ATP-sensitive K(+)-channels by GTP-binding proteins in a mammalian cell line

artículo científico publicado en 1998

Molecular and cellular characteristics of ABCA3 mutations associated with diffuse parenchymal lung diseases in children.

artículo científico publicado en 2011

Molecular and functional diversity of ATP-sensitive K+ channels: the pathophysiological roles and potential drug targets

artículo científico publicado en 2003

Molecular properties of the glucosaminidase AcmA from Lactococcus lactis MG1363: mutational and biochemical analyses

artículo científico publicado en 2009

Molecular properties of the putative autolysin Atl(WM) encoded by Staphylococcus warneri M: mutational and biochemical analyses of the amidase and glucosaminidase domains

artículo científico publicado en 2008

Multiminute oscillations in mouse substantia nigra pars reticulata neurons in vitro

artículo científico publicado en 2004

Nardilysin Is Required for Maintaining Pancreatic β-Cell Function.

artículo científico publicado en 2016

Neuroprotection by KATP channels.

artículo científico publicado en 2005

Niemann-Pick type C disease: novel NPC1 mutations and characterization of the concomitant acid sphingomyelinase deficiency

artículo científico publicado en 2005

Noc2, a putative zinc finger protein involved in exocytosis in endocrine cells

artículo científico publicado en 1997

Novel psychosocial factor involved in diabetes self-care in the Japanese cultural context

scientific article published on 03 January 2019

Nuclear Transport of Kir/Gem Requires Specific Signals and Importin α5 and Is Regulated by Calmodulin and Predicted Serine Phosphorylations

artículo científico publicado en 2007

Once Daily Self-Monitoring of Blood Glucose (SMBG) Improves Glycemic Control in Oral Hypoglycemic Agents (OHA)-Treated Diabetes: SMBG-OHA Follow-Up Study.

artículo científico publicado en 2015

Once-weekly trelagliptin versus daily alogliptin in Japanese patients with type 2 diabetes: a randomised, double-blind, phase 3, non-inferiority study.

artículo científico publicado en 2015

Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-Inflammatory Cytokine Expression in Liver of Diabetic ob/ob Mice.

artículo científico publicado en 2016

Over-expression of facilitative glucose transporter genes in human cancer

artículo científico publicado en 1990

Overall safety and efficacy of high-dose and low-dose intravenous glucocorticoid therapy in patients with moderate-to-severe active Graves' ophthalmopathy

artículo científico publicado en 2016

Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1.

artículo científico publicado en 2010

Palmitate induces reactive oxygen species production and β-cell dysfunction by activating nicotinamide adenine dinucleotide phosphate oxidase through Src signaling

artículo científico publicado en 2013

Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c

artículo científico publicado en 2015

Pharmacokinetic and pharmacodynamic evaluation of linagliptin for the treatment of type 2 diabetes mellitus, with consideration of Asian patient populations

artículo científico publicado en 2016

Pharmacokinetic and pharmacodynamic profiles of canagliflozin in Japanese patients with type 2 diabetes mellitus and moderate renal impairment.

artículo científico publicado en 2014

Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin in Japanese Patients with Type 2 Diabetes Mellitus

artículo científico publicado en 2015

Phosphorylation and functional regulation of ClC-2 chloride channels expressed in Xenopus oocytes by M cyclin-dependent protein kinase

artículo científico publicado en 2002

Plasma gastric inhibitory polypeptide and glucagon-like peptide-1 levels after glucose loading are associated with different factors in Japanese subjects

artículo científico publicado en 2011

Proposal for new diagnostic criteria for low skeletal muscle mass based on computed tomography imaging in Asian adults.

artículo científico publicado en 2016

Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine

artículo científico publicado en 2005

Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure

artículo científico publicado en 2001

Protocol for a large-scale prospective observational study with alogliptin in patients with type 2 diabetes: J-BRAND Registry

artículo científico publicado en 2014

Purkinje cell protein 4 positively regulates neurite outgrowth and neurotransmitter release ⬇️

artículo científico publicado el 10 de junio de 2011

Randomized controlled trial of single-agent glimepiride and pioglitazone in Japanese patients with type 2 diabetes: A comparative study

artículo científico publicado en 2011

Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism

artículo científico publicado en 2009

Real-life glycemic control in patients with type 2 diabetes treated with insulin therapy: A prospective, longitudinal cohort study (Diabetes Distress and Care Registry at Tenri [DDCRT 9]).

artículo científico

Reduced Glycemic Variability and Flexible Graft Function after Islet Transplantation: A Case Report

scientific article published on 20 May 2020

Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction

artículo científico publicado en 2013

Regulation of glucagon-like peptide-1 sensitivity by gut microbiota dysbiosis

artículo científico publicado en 2017

Relationship and factors responsible for regulating fasting and post-challenge plasma glucose levels in the early stage development of type 2 diabetes mellitus.

artículo científico publicado en 2014

Relationship of homocysteine and homocysteine-related vitamins to bone mineral density in Japanese patients with type 2 diabetes

artículo científico publicado en 2011

Renal sodium glucose cotransporter 2 inhibitors as a novel therapeutic approach to treatment of type 2 diabetes: Clinical data and mechanism of action

artículo científico publicado en 2014

Restless legs syndrome in patients with type 2 diabetes: effectiveness of pramipexole therapy

artículo científico publicado en 2014

Reversal of Cushing Pigmentation by Sunitinib

scientific article published on 13 February 2019

Role of GIP receptor signaling in β-cell survival

artículo científico publicado en 2017

Role of clock genes in insulin secretion

artículo científico publicado en 2016

Role of endogenous ROS production in impaired metabolism-secretion coupling of diabetic pancreatic β cells

artículo científico publicado en 2011

Role of mitochondrial phosphate carrier in metabolism-secretion coupling in rat insulinoma cell line INS-1.

artículo científico publicado en 2011

Role of sodium-glucose transporters in glucose uptake of the intestine and kidney

artículo científico publicado en 2012

SIRT5 deacetylates and activates urate oxidase in liver mitochondria of mice

artículo científico publicado en 2012

SUIT, secretory units of islets in transplantation: An index for therapeutic management of islet transplanted patients and its application to type 2 diabetes

artículo científico publicado en 2006

SYR-472, a novel once-weekly dipeptidyl peptidase-4 (DPP-4) inhibitor, in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial

artículo científico publicado en 2013

Safety and efficacy of canagliflozin in Japanese patients with type 2 diabetes mellitus: post hoc subgroup analyses according to body mass index in a 52-week open-label study

artículo científico publicado en 2015

Self-monitoring of blood glucose (SMBG) improves glycaemic control in oral hypoglycaemic agent (OHA)-treated type 2 diabetes (SMBG-OHA study).

artículo científico publicado en 2013

Sensory and motor physiological functions are impaired in gastric inhibitory polypeptide receptor-deficient mice

artículo científico publicado en 2013

Short-term intensive glycemic control improves vibratory sensation in type 2 diabetes

artículo científico publicado en 2008

Sitagliptin add-on to low dosage sulphonylureas: efficacy and safety of combination therapy on glycaemic control and insulin secretion capacity in type 2 diabetes

artículo científico publicado en 2012

Sitagliptin monotherapy has better effect on insulinogenic index than glimepiride monotherapy in Japanese patients with type 2 diabetes mellitus: a 52-week, multicenter, parallel-group randomized controlled trial

artículo científico publicado en 2016

Social orientation and diabetes-related distress in Japanese and American patients with type 2 diabetes

artículo científico publicado en 2014

Solid-phase extraction treatment is required for measurement of active glucagon-like peptide-1 by enzyme-linked immunosorbent assay kit affected by heterophilic antibodies

artículo científico publicado en 2018

Soluble TNF receptors and albuminuria in non-obese Japanese type 2 diabetic patients

artículo científico publicado en 2005

Soluble tumor necrosis factor receptor 2 is independently associated with pulse wave velocity in nonobese Japanese patients with type 2 diabetes mellitus

Soluble vascular cell adhesion molecule-1 is independently associated with soluble tumor necrosis factor receptor 2 in Japanese type 2 diabetic patients

Somatostatin receptor subtype SSTR2 mediates the inhibition of high-voltage-activated calcium channels by somatostatin and its analogue SMS 201-995.

artículo científico publicado en 1994

Sorting nexin 19 regulates the number of dense core vesicles in pancreatic β-cells

artículo científico publicado en 2012

Specific interaction of the potassium channel β-subunit minK with the sarcomeric protein T-cap suggests a T-tubule-myofibril linking system ⬇️

artículo científico publicado el 2 de noviembre de 2001

Sphingosine kinase 1-interacting protein is a novel regulator of glucose-stimulated insulin secretion

artículo científico publicado en 2017

Src activation generates reactive oxygen species and impairs metabolism-secretion coupling in diabetic Goto-Kakizaki and ouabain-treated rat pancreatic islets

artículo científico publicado en 2008

Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β-cells

artículo científico publicado en 2015

Subunit stoichiometry of the pancreatic β-cell ATP-sensitive K+ channel

artículo científico publicado en 1997

Sulfonylurea and glinide reduce insulin content, functional expression of KATP channels, and accelerate apoptotic β-cell death in the chronic phase

artículo científico publicado en 2007

Synthesis and evaluation of 18F-labeled mitiglinide derivatives as positron emission tomography tracers for β-cell imaging

artículo científico publicado en 2014

System for simultaneously monitoring heart and breathing rate in mice using a piezoelectric transducer

artículo científico publicado en 2006

Systems analysis of GLP-1 receptor signaling in pancreatic β-cells

artículo científico publicado en 2011

Targeting β-cell functions in therapy for type 2 diabetes

artículo científico publicado en 2011

Temporal and spatial profiles of ABCA2-expressing oligodendrocytes in the developing rat brain.

artículo científico publicado en 2003

Tetrahydrobiopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice.

artículo científico publicado en 2013

The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus

artículo científico publicado en 2005

The G-Protein-Coupled Long-Chain Fatty Acid Receptor GPR40 and Glucose Metabolism

artículo científico publicado en 2014

The combination of dulaglutide and biguanide reduced bodyweight in Japanese patients with type 2 diabetes

artículo científico publicado en 2016

The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice

artículo científico publicado en 2010

The murine glucagon-like peptide-1 receptor is essential for control of bone resorption.

artículo científico publicado en 2007

The spontaneously diabetic Torii rat with gastroenteropathy

scientific article published on 07 September 2006

Three measures of tumor necrosis factor alpha activity and insulin resistance in nonobese Japanese type 2 diabetic patients

artículo científico publicado en 2005

Three-dimensional ex vivo imaging and analysis of intraportal islet transplants

scientific article published on 25 May 2011

Tissue distribution and species difference of the brain type glucose transporter (GLUT3)

article

Transcriptional regulatory factor X6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high fat diet-induced obesity.

artículo científico publicado en 2012

Troglitazone but not pioglitazone affects ATP-sensitive K(+) channel activity.

artículo científico publicado en 1999

Tunel positive keratinocytes in keratin disease

artículo científico publicado en 2005

Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity

scientific article published on 31 October 2016

Ubiquitination of molluscum body and its implications for pathophysiology

artículo científico publicado en 2006

Update on the efficacy and safety of sodium-glucose cotransporter 2 inhibitors in Asians and non-Asians

artículo científico publicado en 2019

Utility of indices using C-peptide levels for indication of insulin therapy to achieve good glycemic control in Japanese patients with type 2 diabetes

artículo científico publicado en 2011

Voriconazole-induced periostitis in a patient with overlap syndromes

artículo científico publicado en 2014

Which should we ADOPT: sulphonylureas or glitazones?

scientific article published on 01 July 2007

cDNA sequence, gene structure, and chromosomal localization of the human ATP-sensitive potassium channel, uKATP-1, gene (KCNJ8)

artículo científico publicado en 1995

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