Lista de obras - Thomas Höfer - Dominio Público Uruguay

A global circadian repressor controls antiphasic expression of metabolic genes in Neurospora

article

A resolution of the chemotactic wave paradox

A second-order approach to metabolic control analysis

artículo científico publicado en 1993

Activation of the transcription factor NFAT1: concerted or modular regulation?

artículo científico publicado en 2005

Adaptation of humoral memory

artículo científico publicado en 2006

Adaptation to host cell environment during experimental evolution of Zika virus

artículo científico publicado en 2022

Allosteric regulation of the transcription factor NFAT1 by multiple phosphorylation sites: a mathematical analysis

artículo científico publicado en 2003

Antiviral interferon response at single-cell resolution

artículo científico publicado en 2018

Assembly of multiprotein complexes that control genome function

artículo científico publicado en 2009

Asynchronous nuclear cycles in multinucleated <i>Plasmodium falciparum</i> facilitate rapid proliferation

artículo científico publicado en 2022

CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo

artículo científico publicado en 2015

CD8(+) T cell diversification by asymmetric cell division

artículo científico publicado en 2015

Circadian conformational change of the Neurospora clock protein FREQUENCY triggered by clustered hyperphosphorylation of a basic domain.

artículo científico publicado en 2011

Clonal selection drives protective memory B cell responses in controlled human malaria infection

artículo científico publicado en 2018

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.

artículo científico publicado en 2010

Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses

artículo científico

Competition for cytokines: T(reg) cells take all

scientific article published on 01 December 2007

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.

artículo científico publicado en 2014

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

artículo científico publicado en 2010

Control and plasticity of intercellular calcium waves in astrocytes: a modeling approach.

artículo científico publicado en 2002

Control of signal transduction cycles: general results and application to the Jak-Stat pathway.

artículo científico publicado en 2006

Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems

artículo científico publicado en 2015

Decoding of calcium oscillations by phosphorylation cycles: analytic results

artículo científico publicado en 2007

Dictyostelium discoideum: cellular self-organization in an excitable biological medium

artículo científico publicado en 1995

Differentiation-based model of hematopoietic stem cell functions and lineage pathways

scientific article published on 24 July 2018

Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.

artículo científico publicado en 2007

Disparate individual fates compose robust CD8+ T cell immunity

artículo científico publicado en 2013

Do haematopoietic stem cells age?

scientific article published on 18 November 2019

Early emergence of T central memory precursors programs clonal dominance during chronic viral infection

artículo científico publicado en 2020

Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis

artículo científico publicado en 2022

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.

artículo científico publicado en 2015

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model

artículo científico publicado en 2002

Genome-wide nucleosome positioning during embryonic stem cell development

artículo científico publicado en 2012

Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration

artículo científico publicado en 2012

Hidden long-range memories of growth and cycle speed correlate cell cycles in lineage trees

scientific article published on 23 January 2020

Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations

artículo científico publicado en 2014

In Remembrance: Reinhart Heinrich 1946–2006

artículo científico publicado en 2007

Individual T helper cells have a quantitative cytokine memory

artículo científico publicado en 2014

Intercellular Ca2+ wave propagation through gap-junctional Ca2+ diffusion: a theoretical study

artículo científico publicado en 2001

Kinetic models of phosphorylation cycles: a systematic approach using the rapid-equilibrium approximation for protein-protein interactions

artículo científico publicado en 2005

Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation Mutant

scientific article (publication date: December 2015)

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

artículo científico publicado en 2008

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis

scientific article published on 28 April 2022

Mathematical modelling of DNA replication reveals a trade-off between coherence of origin activation and robustness against rereplication

artículo científico publicado en 2010

Model of intercellular calcium oscillations in hepatocytes: synchronization of heterogeneous cells

artículo científico publicado en 1999

Modelling and simulating interleukin-10 production and regulation by macrophages after stimulation with an immunomodulator of parasitic nematodes.

artículo científico publicado en 2009

Modelling of simple and complex calcium oscillations. From single-cell responses to intercellular signalling.

artículo científico publicado en 2002

Models of IP3 and Ca2+ oscillations: frequency encoding and identification of underlying feedbacks

artículo científico publicado en 2006

Molecular networks and system-level properties

artículo científico publicado en 2009

Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response

artículo científico publicado en 2012

Multisite protein phosphorylation--from molecular mechanisms to kinetic models

scientific article published on 29 April 2009

NFATc1 autoregulation: a crucial step for cell-fate determination

scientific article published on 22 August 2006

Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development.

artículo científico publicado en 2014

On the kinetic design of transcription

artículo científico publicado en 2005

Phosphorylation modulates rapid nucleocytoplasmic shuttling and cytoplasmic accumulation of Neurospora clock protein FRQ on a circadian time scale.

artículo científico publicado en 2009

Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks ⬇️

artículo científico publicado el 29 de julio de 2011

Robustness of DNA repair through collective rate control

artículo científico publicado en 2014

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells

artículo científico publicado en 2014

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

artículo científico publicado en 2010

Specificity, propagation, and memory of pericentric heterochromatin

artículo científico publicado en 2014

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

artículo científico publicado en 2013

Stem cell homeostasis by integral feedback through the niche

artículo científico publicado en 2018

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.

artículo científico publicado en 2010

SysBioMed report: advancing systems biology for medical applications.

artículo científico

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

artículo científico publicado en 2015

The Neurospora photoreceptor VIVID exerts negative and positive control on light sensing to achieve adaptation.

artículo científico publicado en 2013

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

artículo científico publicado en 2010

Three-Dimensional Gradients of Cytokine Signaling between T Cells

artículo científico publicado en 2015

Timing control in regulatory networks by multisite protein modifications

scientific article published on 23 September 2010

Transcriptional control networks of cell differentiation: insights from helper T lymphocytes

artículo científico publicado en 2004

Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions.

artículo científico publicado en 2007

[Calcium waves between glial cells: how astrocytes communicate]

artículo científico publicado en 2003

Lista de obras de Thomas Höfer

A global circadian repressor controls antiphasic expression of metabolic genes in Neurospora

A resolution of the chemotactic wave paradox

A second-order approach to metabolic control analysis

Activation of the transcription factor NFAT1: concerted or modular regulation?

Adaptation of humoral memory

Adaptation to host cell environment during experimental evolution of Zika virus

Allosteric regulation of the transcription factor NFAT1 by multiple phosphorylation sites: a mathematical analysis

Antiviral interferon response at single-cell resolution

Assembly of multiprotein complexes that control genome function

Asynchronous nuclear cycles in multinucleated <i>Plasmodium falciparum</i> facilitate rapid proliferation

CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo

CD8(+) T cell diversification by asymmetric cell division

Circadian conformational change of the Neurospora clock protein FREQUENCY triggered by clustered hyperphosphorylation of a basic domain.

Clonal selection drives protective memory B cell responses in controlled human malaria infection

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.

Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses

Competition for cytokines: T(reg) cells take all

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.

Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

Control and plasticity of intercellular calcium waves in astrocytes: a modeling approach.

Control of signal transduction cycles: general results and application to the Jak-Stat pathway.

Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems

Decoding of calcium oscillations by phosphorylation cycles: analytic results

Dictyostelium discoideum: cellular self-organization in an excitable biological medium

Differentiation-based model of hematopoietic stem cell functions and lineage pathways

Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.

Disparate individual fates compose robust CD8+ T cell immunity

Do haematopoietic stem cells age?

Early emergence of T central memory precursors programs clonal dominance during chronic viral infection

Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.

GATA-3 transcriptional imprinting in Th2 lymphocytes: a mathematical model

Genome-wide nucleosome positioning during embryonic stem cell development

Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration

Hidden long-range memories of growth and cycle speed correlate cell cycles in lineage trees

Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations

In Remembrance: Reinhart Heinrich 1946–2006

Individual T helper cells have a quantitative cytokine memory

Intercellular Ca2+ wave propagation through gap-junctional Ca2+ diffusion: a theoretical study

Kinetic models of phosphorylation cycles: a systematic approach using the rapid-equilibrium approximation for protein-protein interactions

Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation Mutant

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis

Mathematical modelling of DNA replication reveals a trade-off between coherence of origin activation and robustness against rereplication

Model of intercellular calcium oscillations in hepatocytes: synchronization of heterogeneous cells

Modelling and simulating interleukin-10 production and regulation by macrophages after stimulation with an immunomodulator of parasitic nematodes.

Modelling of simple and complex calcium oscillations. From single-cell responses to intercellular signalling.

Models of IP3 and Ca2+ oscillations: frequency encoding and identification of underlying feedbacks

Molecular networks and system-level properties

Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response

Multisite protein phosphorylation--from molecular mechanisms to kinetic models

NFATc1 autoregulation: a crucial step for cell-fate determination

Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development.

On the kinetic design of transcription

Phosphorylation modulates rapid nucleocytoplasmic shuttling and cytoplasmic accumulation of Neurospora clock protein FRQ on a circadian time scale.

Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks ⬇️

Robustness of DNA repair through collective rate control

Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

Specificity, propagation, and memory of pericentric heterochromatin

Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation.

Stem cell homeostasis by integral feedback through the niche

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.

SysBioMed report: advancing systems biology for medical applications.

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

The Neurospora photoreceptor VIVID exerts negative and positive control on light sensing to achieve adaptation.

The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes

Three-Dimensional Gradients of Cytokine Signaling between T Cells

Timing control in regulatory networks by multisite protein modifications

Transcriptional control networks of cell differentiation: insights from helper T lymphocytes

Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions.

[Calcium waves between glial cells: how astrocytes communicate]