Lista de obras - Vasili Hauryliuk - Dominio Público Uruguay

A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes

scientific article published on 11 May 2020

A widespread toxin-antitoxin system exploiting growth control via alarmone signaling

scientific article published on 28 April 2020

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

scientific article published on 28 December 2018

Aim-less translation: loss of Saccharomyces cerevisiae mitochondrial translation initiation factor mIF3/Aim23 leads to unbalanced protein synthesis.

artículo científico publicado en 2016

An ancient family of SelB elongation factor-like proteins with a broad but disjunct distribution across archaea ⬇️

artículo científico publicado el 21 de enero de 2011

An evolutionary ratchet leading to loss of elongation factors in eukaryotes

artículo científico publicado en 2014

Analysis of nucleotide pools in bacteria using HPLC-MS in HILIC mode

scientific article published on 18 July 2019

Antibacterial activity of the nitrovinylfuran G1 (Furvina) and its conversion products.

artículo científico publicado en 2016

Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest

artículo científico publicado en 2018

Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

artículo científico publicado en 2016

Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp

artículo científico publicado en 2016

Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis

artículo científico publicado en 2024

Class-1 release factor eRF1 promotes GTP binding by class-2 release factor eRF3

artículo científico publicado en 2006

Composition of the outgrowth medium modulates wake-up kinetics and ampicillin sensitivity of stringent and relaxed Escherichia coli.

artículo científico

Does the ribosome have initiation and elongation modes of translation?

scientific article published on 25 May 2009

Evaluation of the characteristics of leucyl-tRNA synthetase (LeuRS) inhibitor AN3365 in combination with different antibiotic classes

artículo científico publicado en 2016

Evolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components

artículo científico publicado en 2008

Evolution of translational machinery: could translation termination come into being before elongation?

artículo científico publicado en 2007

Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae

artículo científico publicado en 2012

From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis

artículo científico publicado en 2015

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding

artículo científico publicado en 2009

GTPases IF2 and EF-G bind GDP and the SRL RNA in a mutually exclusive manner

artículo científico publicado en 2012

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

artículo científico publicado en 2005

HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp

artículo científico publicado en 2017

In Vitro Studies of Persister Cells

scientific article published on 11 November 2020

Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

artículo científico publicado en 2019

Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)

artículo científico publicado en 2013

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor

artículo científico publicado en 2017

Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.

artículo científico publicado en 2017

Persisters-as elusive as ever

artículo científico publicado en 2016

Positive allosteric feedback regulation of the stringent response enzyme RelA by its product

artículo científico publicado en 2012

Protein biosynthesis in mitochondria

artículo científico

Reanalysis of Proteomics Results Fails To Detect MazF-Mediated Stress Proteins

scientific article published on 11 June 2019

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells.

artículo científico publicado en 2018

Recent functional insights into the role of (p)ppGpp in bacterial physiology

artículo científico publicado en 2015

Reply to Holden and Errington, "Type II Toxin-Antitoxin Systems and Persister Cells"

artículo científico publicado en 2018

Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae

scientific article published on 28 February 2019

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system

artículo científico publicado en 2021

Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40 ⬇️

artículo científico publicado el 14 de diciembre de 2011

Single-molecule investigations of the stringent response machinery in living bacterial cells

artículo científico publicado en 2011

Small Alarmone Synthetases as novel bacterial RNA-binding proteins.

artículo científico publicado en 2017

Splitting of the posttermination ribosome into subunits by the concerted action of RRF and EF-G.

artículo científico publicado en 2005

Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP

artículo científico publicado en 2020

Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.

artículo científico publicado en 2018

Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics

artículo científico publicado en 2022

Structural basis for antibiotic resistance mediated by the ABCF ATPase VmlR

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

scientific article published on 11 June 2021

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams.

artículo científico publicado en 2017

The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis

scientific article published on 02 August 2019

The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life

artículo científico publicado en 2011

The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome

artículo científico publicado en 2008

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

artículo científico publicado en 2008

The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA.

artículo científico publicado en 2018

The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis

artículo científico publicado en 2016

Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp

artículo científico publicado en 2010

Thermodynamics of GTP and GDP binding to bacterial initiation factor 2 suggests two types of structural transitions.

artículo científico publicado en 2009

Two-step selection of mRNAs in initiation of protein synthesis

artículo científico publicado en 2006

Uncovering new families and folds in the natural protein universe

artículo científico publicado en 2023

What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds

[GTPases of prokaryotic translational apparatus]

scientific article published on 01 September 2006

Lista de obras de Vasili Hauryliuk

A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes

A widespread toxin-antitoxin system exploiting growth control via alarmone signaling

ABCF ATPases Involved in Protein Synthesis, Ribosome Assembly and Antibiotic Resistance: Structural and Functional Diversification across the Tree of Life

Aim-less translation: loss of Saccharomyces cerevisiae mitochondrial translation initiation factor mIF3/Aim23 leads to unbalanced protein synthesis.

An ancient family of SelB elongation factor-like proteins with a broad but disjunct distribution across archaea ⬇️

An evolutionary ratchet leading to loss of elongation factors in eukaryotes

Analysis of nucleotide pools in bacteria using HPLC-MS in HILIC mode

Antibacterial activity of the nitrovinylfuran G1 (Furvina) and its conversion products.

Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest

Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp

Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis

Class-1 release factor eRF1 promotes GTP binding by class-2 release factor eRF3

Composition of the outgrowth medium modulates wake-up kinetics and ampicillin sensitivity of stringent and relaxed Escherichia coli.

Does the ribosome have initiation and elongation modes of translation?

Evaluation of the characteristics of leucyl-tRNA synthetase (LeuRS) inhibitor AN3365 in combination with different antibiotic classes

Evolution of nonstop, no-go and nonsense-mediated mRNA decay and their termination factor-derived components

Evolution of translational machinery: could translation termination come into being before elongation?

Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae

From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding

GTPases IF2 and EF-G bind GDP and the SRL RNA in a mutually exclusive manner

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp

In Vitro Studies of Persister Cells

Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor

Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.

Persisters-as elusive as ever

Positive allosteric feedback regulation of the stringent response enzyme RelA by its product

Protein biosynthesis in mitochondria

Reanalysis of Proteomics Results Fails To Detect MazF-Mediated Stress Proteins

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells.

Recent functional insights into the role of (p)ppGpp in bacterial physiology

Reply to Holden and Errington, "Type II Toxin-Antitoxin Systems and Persister Cells"

Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae

Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system

Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40 ⬇️

Single-molecule investigations of the stringent response machinery in living bacterial cells

Small Alarmone Synthetases as novel bacterial RNA-binding proteins.

Splitting of the posttermination ribosome into subunits by the concerted action of RRF and EF-G.

Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP

Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP.

Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics

Structural basis for antibiotic resistance mediated by the ABCF ATPase VmlR

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams.

The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis

The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life

The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome

The pretranslocation ribosome is targeted by GTP-bound EF-G in partially activated form

The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA.

The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis

Thermodynamic characterization of ppGpp binding to EF-G or IF2 and of initiator tRNA binding to free IF2 in the presence of GDP, GTP, or ppGpp

Thermodynamics of GTP and GDP binding to bacterial initiation factor 2 suggests two types of structural transitions.

Two-step selection of mRNAs in initiation of protein synthesis

Uncovering new families and folds in the natural protein universe

What is hidden in the darkness? Deep-learning assisted large-scale protein family curation uncovers novel protein families and folds

[GTPases of prokaryotic translational apparatus]