Lista de obras - Quentin Kaas - Dominio Público Uruguay

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

scientific article published on 27 March 2020

A new "era" for cyclotide sequencing.

artículo científico publicado en 2010

A novel 4/7-conotoxin LvIA from Conus lividus that selectively blocks 3 2 vs. 6/ 3 2 3 nicotinic acetylcholine receptors

artículo científico publicado en 2014

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

scientific article published on 25 July 2019

A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic, and peptidomic analysis

artículo científico publicado en 2013

Accurate de novo design of hyperstable constrained peptides

artículo científico publicado en 2016

Analysis and classification of circular proteins in CyBase

artículo científico publicado en 2010

ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures

artículo científico publicado en 2011

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins.

artículo científico publicado en 2017

ArachnoServer: a database of protein toxins from spiders

artículo científico publicado en 2009

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

artículo científico publicado en 2017

Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods.

artículo científico publicado en 2018

Bioinformatics-Aided Venomics

artículo científico publicado en 2015

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

artículo científico publicado el 3 de marzo de 2011

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.

artículo científico publicado en 2015

Computational Studies of Snake Venom Toxins.

artículo científico publicado en 2017

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

artículo científico publicado en 2018

ConoServer, a database for conopeptide sequences and structures

artículo científico publicado en 2007

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

artículo científico publicado en 2012

Conopeptide characterization and classifications: an analysis using ConoServer

artículo científico publicado en 2010

Conotoxins: Chemistry and Biology

scientific article published on 21 October 2019

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

artículo científico publicado en 2015

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

artículo científico publicado en 2017

Cyclization of conotoxins to improve their biopharmaceutical properties.

artículo científico publicado en 2010

Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom

artículo científico publicado en 2012

Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor

artículo científico publicado en 2012

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

artículo científico publicado en 2015

Despite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding Modes

artículo científico publicado en 2009

Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor

scientific article published on 29 April 2013

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

artículo científico publicado en 2018

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors

artículo científico publicado en 2017

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

artículo científico publicado en 2020

Discovery, synthesis, and structure-activity relationships of conotoxins.

artículo científico publicado en 2014

Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor

scientific article published on 21 August 2018

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

artículo científico publicado en 2015

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

artículo científico publicado en 2016

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3.

artículo científico publicado en 2013

Engineering of conotoxins for the treatment of pain

artículo científico publicado en 2011

Enhanced Activity against Multidrug-Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway

artículo científico publicado en 2020

High-affinity cyclic peptide matriptase inhibitors

artículo científico publicado en 2013

High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide

artículo científico publicado en 2004

IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN.

artículo científico

IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains

artículo científico publicado en 2005

IMGT-Kaleidoscope, the formal IMGT-ONTOLOGY paradigm

artículo científico

IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T cell receptors, MHC, IgSF and MhcSF.

artículo científico publicado en 2009

IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data

artículo científico publicado en 2004

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

artículo científico publicado en 2010

In Silico Design of MDM2-Targeting Peptides from a Naturally Occurring Constrained Peptide

artículo científico publicado en 2019

Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor

artículo científico publicado en 2019

KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007

artículo científico publicado en 2007

Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding.

artículo científico publicado en 2015

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.

artículo científico publicado en 2015

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae

artículo científico publicado en 2015

Modelling the interactions between animal venom peptides and membrane proteins

artículo científico publicado en 2017

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases.

artículo científico publicado en 2018

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

artículo científico publicado en 2010

Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

scientific article published on 07 June 2019

NMR of plant proteins

artículo científico publicado en 2013

Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation - Suggestion of a Binding Mode at the α7 nAChR

artículo científico publicado en 2019

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.

artículo científico publicado en 2013

Prediction and characterization of cyclic proteins from sequences in three domains of life

artículo científico publicado en 2013

Prediction of disulfide dihedral angles using chemical shifts

artículo científico publicado en 2018

Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors.

artículo científico publicado en 2017

SCORE: predicting the core of protein models

artículo científico publicado en 2001

Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist

artículo científico publicado en 2018

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

scientific article published on 21 July 2018

Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene

scientific article published on 12 May 2020

Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA

scientific article published on 07 February 2020

The KNOTTIN website and database: a new information system dedicated to the knottin scaffold.

artículo científico publicado en 2004

The [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide retains the specific Arg(-1)-Asp8 salt bridge but reveals discrepancies between NMR data and molecular dynamics simulations.

artículo científico publicado en 2002

The evolution of Momordica cyclic peptides

artículo científico publicado en 2014

Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity

artículo científico publicado en 2013

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors

artículo científico publicado en 2017

αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.

artículo científico publicado en 2017

Lista de obras de Quentin Kaas

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

A new "era" for cyclotide sequencing.

A novel 4/7-conotoxin LvIA from Conus lividus that selectively blocks 3 2 vs. 6/ 3 2 3 nicotinic acetylcholine receptors

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic, and peptidomic analysis

Accurate de novo design of hyperstable constrained peptides

Analysis and classification of circular proteins in CyBase

ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins.

ArachnoServer: a database of protein toxins from spiders

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods.

Bioinformatics-Aided Venomics

Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.

Computational Studies of Snake Venom Toxins.

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

ConoServer, a database for conopeptide sequences and structures

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

Conopeptide characterization and classifications: an analysis using ConoServer

Conotoxins: Chemistry and Biology

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

Cyclization of conotoxins to improve their biopharmaceutical properties.

Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom

Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

Despite a Conserved Cystine Knot Motif, Different Cyclotides Have Different Membrane Binding Modes

Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

Discovery, synthesis, and structure-activity relationships of conotoxins.

Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3.

Engineering of conotoxins for the treatment of pain

Enhanced Activity against Multidrug-Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway

High-affinity cyclic peptide matriptase inhibitors

High-resolution X-ray structure of the unexpectedly stable dimer of the [Lys(-2)-Arg(-1)-des(17-21)]endothelin-1 peptide

IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN.

IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains

IMGT-Kaleidoscope, the formal IMGT-ONTOLOGY paradigm

IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T cell receptors, MHC, IgSF and MhcSF.

IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

In Silico Design of MDM2-Targeting Peptides from a Naturally Occurring Constrained Peptide

Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor

KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007

Key residues in the nicotinic acetylcholine receptor β2 subunit contribute to α-conotoxin LvIA binding.

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1.

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae

Modelling the interactions between animal venom peptides and membrane proteins

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases.

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

NMR of plant proteins

Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation - Suggestion of a Binding Mode at the α7 nAChR

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.

Prediction and characterization of cyclic proteins from sequences in three domains of life

Prediction of disulfide dihedral angles using chemical shifts

Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors.

SCORE: predicting the core of protein models

Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene

Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA

The KNOTTIN website and database: a new information system dedicated to the knottin scaffold.

The [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide retains the specific Arg(-1)-Asp8 salt bridge but reveals discrepancies between NMR data and molecular dynamics simulations.

The evolution of Momordica cyclic peptides

Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors

αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.