Lista de obras - Sandip Patel - Dominio Público Uruguay

A "mix-and-match" approach to designing Ca(2+) microdomains at membrane-contact sites.

artículo científico publicado en 2014

A computational model of lysosome-ER Ca2+ microdomains

artículo científico publicado en 2014

A link between LRRK2, autophagy and NAADP-mediated endolysosomal calcium signalling

artículo científico

A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii

artículo científico publicado en 2021

A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate.

artículo científico publicado en 2010

Acidic Ca(2+) stores come to the fore

artículo científico publicado en 2011

Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure

artículo científico publicado en 2010

An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

artículo científico publicado en 2017

An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals

artículo científico publicado en 2010

Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo.

artículo científico publicado en 2016

Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophysiology

artículo científico publicado en 2018

Calcium signaling at ER membrane contact sites

artículo científico

Carbon nanopipettes characterize calcium release pathways in breast cancer cells

artículo científico publicado en 2008

Convergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinases

artículo científico publicado en 2014

Coupling acidic organelles with the ER through Ca²⁺ microdomains at membrane contact sites.

artículo científico

Decorin Activates the Epidermal Growth Factor Receptor and Elevates Cytosolic Ca2+in A431 Carcinoma Cells

artículo científico publicado en 1998

Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints

artículo científico publicado en 2010

Determination of cellular nicotinic acid-adenine dinucleotide phosphate (NAADP) levels

artículo científico publicado en 2004

Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation.

artículo científico publicado en 2010

Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals

artículo científico publicado en 2012

Domain assembly of NAADP-gated two-pore channels ⬇️

artículo científico publicado el 1 de enero de 2012

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

artículo científico publicado en 2015

Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx

artículo científico publicado en 2016

Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts

artículo científico publicado en 2015

Evolution of acidic Ca²⁺ stores and their resident Ca²⁺-permeable channels

artículo científico publicado en 2014

Function and dysfunction of two-pore channels

artículo científico publicado en 2015

In with the TRP channels: intracellular functions for TRPM1 and TRPM2.

artículo científico publicado en 2009

Inducible nitric-oxide synthase attenuates vasopressin-dependent Ca2+ signaling in rat hepatocytes.

artículo científico publicado en 2002

Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.

artículo científico publicado en 2015

Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view

artículo científico publicado en 2014

Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A.

artículo científico publicado en 2016

Isolated pores dissected from human two-pore channel 2 are functional

artículo científico publicado en 2016

Kinetic analysis of inositol trisphosphate binding to pure inositol trisphosphate receptors using scintillation proximity assay

scientific article published on 01 April 1996

Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP

artículo científico publicado en 2012

Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1

artículo científico publicado en 2012

Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.

artículo científico publicado en 2010

Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation

artículo científico publicado en 2006

Metabolism of the novel Ca2+-mobilizing messenger nicotinic acid-adenine dinucleotide phosphate via a 2'-specific Ca2+-dependent phosphatase

artículo científico publicado en 2002

Methods for monitoring lysosomal morphology

artículo científico publicado en 2015

Modulation of NAADP (nicotinic acid-adenine dinucleotide phosphate) receptors by K+ ions: evidence for multiple NAADP receptor conformations

artículo científico publicado en 2003

Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP).

artículo científico publicado en 2003

Molecular and functional characterization of inositol trisphosphate receptors during early zebrafish development.

artículo científico publicado en 2007

Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin

artículo científico publicado en 2008

Molecular characterization of a novel intracellular ADP-ribosyl cyclase

artículo científico publicado en 2007

NAADP binding to its target protein in sea urchin eggs requires phospholipids

artículo científico publicado en 2005

NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs

artículo científico publicado en 2002

NAADP on target

artículo científico

NAADP on the up in pancreatic beta cells-a sweet message?

artículo científico publicado en 2003

NAADP-evoked Ca2+ signals through two-pore channel-1 require arginine residues in the first S4-S5 linker

artículo científico publicado en 2017

NAADP-induced Ca2+ release -- a new signalling pathway.

artículo científico publicado en 2004

NAADP-induced calcium release in sea urchin eggs

artículo científico publicado en 2000

NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata

artículo científico publicado en 2009

NAADP-sensitive two-pore channels are present and functional in gastric smooth muscle cells

artículo científico publicado en 2014

NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms

artículo científico publicado en 2015

Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes

artículo científico publicado en 2011

Nicotinic acid adenine dinucleotide phosphate potentiates neurite outgrowth

artículo científico publicado en 2004

Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells

artículo científico publicado en 2003

Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells

artículo científico publicado en 2012

Probing the Complexities of Astrocyte Calcium Signaling

artículo científico publicado en 2016

Recruitment of NAADP-sensitive acidic Ca2+ stores by glutamate.

artículo científico publicado en 2009

Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells

artículo científico publicado en 2005

Signalling at membrane contact sites: two membranes come together to handle second messengers

artículo científico publicado en 2016

Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate

artículo científico publicado en 2002

Sperm deliver a new second messenger: NAADP

artículo científico publicado en 2003

TPC1 Knockout Knocks Out TPC1.

artículo científico publicado en 2015

Targeting mitochondria for neuroprotection in Parkinson disease

artículo científico publicado en 2014

The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?

artículo científico publicado en 2012

The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP.

artículo científico publicado en 2013

The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

artículo científico publicado en 2014

The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.

artículo científico publicado en 2011

The intracellular Ca²⁺ channels of membrane traffic

artículo científico publicado en 2012

The signaling protein CD38 is essential for early embryonic development

artículo científico publicado en 2012

Time sensing by NAADP receptors.

artículo científico publicado en 2006

Transgenic mice expressing a cameleon fluorescent Ca2+ indicator in astrocytes and Schwann cells allow study of glial cell Ca2+ signals in situ and in vivo

artículo científico publicado en 2009

Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels

artículo científico publicado en 2011

Triggering of Ca2+ signals by NAADP-gated two-pore channels: a role for membrane contact sites?

artículo científico publicado en 2012

Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed

artículo científico publicado en 2016

Two-pore channels and disease.

artículo científico publicado en 2018

Two-pore channels at the intersection of endolysosomal membrane traffic

artículo científico publicado en 2015

Two-pore channels open up

artículo científico publicado en 2018

Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels.

artículo científico publicado en 2014

Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand

artículo científico publicado en 2000

Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, in the brain

scientific article published on 01 November 2000

Lista de obras de Sandip Patel

A "mix-and-match" approach to designing Ca(2+) microdomains at membrane-contact sites.

A computational model of lysosome-ER Ca2+ microdomains

A link between LRRK2, autophagy and NAADP-mediated endolysosomal calcium signalling

A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii

A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate.

Acidic Ca(2+) stores come to the fore

Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure

An Endosomal NAADP-Sensitive Two-Pore Ca2+ Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals

Ca2+/H+ exchange by acidic organelles regulates cell migration in vivo.

Calcium Deregulation: Novel Insights to Understand Friedreich's Ataxia Pathophysiology

Calcium signaling at ER membrane contact sites

Carbon nanopipettes characterize calcium release pathways in breast cancer cells

Convergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinases

Coupling acidic organelles with the ER through Ca²⁺ microdomains at membrane contact sites.

Decorin Activates the Epidermal Growth Factor Receptor and Elevates Cytosolic Ca2+in A431 Carcinoma Cells

Degeneration of an intracellular ion channel in the primate lineage by relaxation of selective constraints

Determination of cellular nicotinic acid-adenine dinucleotide phosphate (NAADP) levels

Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation.

Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals

Domain assembly of NAADP-gated two-pore channels ⬇️

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx

Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts

Evolution of acidic Ca²⁺ stores and their resident Ca²⁺-permeable channels

Function and dysfunction of two-pore channels

In with the TRP channels: intracellular functions for TRPM1 and TRPM2.

Inducible nitric-oxide synthase attenuates vasopressin-dependent Ca2+ signaling in rat hepatocytes.

Inhibition of NAADP signalling on reperfusion protects the heart by preventing lethal calcium oscillations via two-pore channel 1 and opening of the mitochondrial permeability transition pore.

Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view

Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A.

Isolated pores dissected from human two-pore channel 2 are functional

Kinetic analysis of inositol trisphosphate binding to pure inositol trisphosphate receptors using scintillation proximity assay

Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP

Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1

Membrane topology of NAADP-sensitive two-pore channels and their regulation by N-linked glycosylation.

Messenger-specific role for nicotinic acid adenine dinucleotide phosphate in neuronal differentiation

Metabolism of the novel Ca2+-mobilizing messenger nicotinic acid-adenine dinucleotide phosphate via a 2'-specific Ca2+-dependent phosphatase

Methods for monitoring lysosomal morphology

Modulation of NAADP (nicotinic acid-adenine dinucleotide phosphate) receptors by K+ ions: evidence for multiple NAADP receptor conformations

Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP).

Molecular and functional characterization of inositol trisphosphate receptors during early zebrafish development.

Molecular characterization of a novel cell surface ADP-ribosyl cyclase from the sea urchin

Molecular characterization of a novel intracellular ADP-ribosyl cyclase

NAADP binding to its target protein in sea urchin eggs requires phospholipids

NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs

NAADP on target

NAADP on the up in pancreatic beta cells-a sweet message?

NAADP-evoked Ca2+ signals through two-pore channel-1 require arginine residues in the first S4-S5 linker

NAADP-induced Ca2+ release -- a new signalling pathway.

NAADP-induced calcium release in sea urchin eggs

NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata

NAADP-sensitive two-pore channels are present and functional in gastric smooth muscle cells

NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms

Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes

Nicotinic acid adenine dinucleotide phosphate potentiates neurite outgrowth

Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells

Photoaffinity labeling of nicotinic acid adenine dinucleotide phosphate (NAADP) targets in mammalian cells

Probing the Complexities of Astrocyte Calcium Signaling

Recruitment of NAADP-sensitive acidic Ca2+ stores by glutamate.

Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells

Signalling at membrane contact sites: two membranes come together to handle second messengers

Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate

Sperm deliver a new second messenger: NAADP

TPC1 Knockout Knocks Out TPC1.

Targeting mitochondria for neuroprotection in Parkinson disease

The Molecular Basis for Ca2+ Signalling by NAADP: Two-Pore Channels in a Complex?

The N-terminal region of two-pore channel 1 regulates trafficking and activation by NAADP.

The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.

The intracellular Ca²⁺ channels of membrane traffic

The signaling protein CD38 is essential for early embryonic development

Time sensing by NAADP receptors.

Transgenic mice expressing a cameleon fluorescent Ca2+ indicator in astrocytes and Schwann cells allow study of glial cell Ca2+ signals in situ and in vivo

Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels

Triggering of Ca2+ signals by NAADP-gated two-pore channels: a role for membrane contact sites?

Two-pore Channels Enter the Atomic Era: Structure of Plant TPC Revealed

Two-pore channels and disease.

Two-pore channels at the intersection of endolysosomal membrane traffic