Lista de obras - Jean-Baptiste Demoulin - Dominio Público Uruguay

A minimal connected network of transcription factors regulated in human tumors and its application to the quest for universal cancer biomarkers

artículo científico publicado en 2012

ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines

artículo científico publicado en 2014

ABCB1 1199G>A polymorphism (rs2229109) affects the transport of imatinib, nilotinib and dasatinib.

artículo científico publicado en 2016

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota.

artículo científico publicado en 2015

Autoinhibition of the platelet-derived growth factor beta-receptor tyrosine kinase by its C-terminal tail.

artículo científico publicado en 2004

CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I.

artículo científico publicado en 2003

Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway

artículo científico publicado en 2014

Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein

artículo científico publicado en 2010

Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9

artículo científico publicado en 1999

ETV6-PDGFRB and FIP1L1-PDGFRA stimulate human hematopoietic progenitor cell proliferation and differentiation into eosinophils: the role of nuclear factor-κB.

artículo científico publicado en 2012

FOXO transcription factors in cancer development and therapy

artículo científico

Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition

artículo científico publicado en 2011

Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor

artículo científico publicado en 2004

Global microRNA profiling of well-differentiated small intestinal neuroendocrine tumors.

artículo científico publicado en 2013

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation

artículo científico publicado en 2018

Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets

artículo científico publicado en 2011

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

artículo científico publicado en 2016

Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling

artículo científico publicado en 2014

Impact of ABCB1 1236C > T-2677G > T-3435C > T polymorphisms on the anti-proliferative activity of imatinib, nilotinib, dasatinib and ponatinib

artículo científico publicado en 2016

Inflammation-induced cholestasis in cancer cachexia

artículo científico publicado en 2020

Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling

scientific article published in 2000

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

artículo científico publicado en 2005

JAK2, the JAK2 V617F mutant and cytokine receptors.

artículo científico publicado en 2006

KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia

artículo científico publicado en 2010

Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis

artículo científico publicado en 2009

Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF.

artículo científico publicado en 2003

MAP kinase activation by interleukin-9 in lymphoid and mast cell lines

artículo científico publicado en 2003

Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.

artículo científico publicado en 2011

New insights into the mechanisms of hematopoietic cell transformation by activated receptor tyrosine kinases

artículo científico publicado en 2010

No PDGF receptor signal in pericytes without endosialin?

artículo científico publicado en 2010

Novel COL4A1-VEGFD gene fusion in myofibroma

artículo científico publicado en 2021

Novel head-to-head gene fusion of MLL with ZC3H13 in a JAK2 V617F-positive patient with essential thrombocythemia without blast cells

article

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

artículo científico publicado en 2009

Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes

scientific article published on 25 October 2010

Oxidative DNA damage by t-butyl hydroperoxide causes DNA single strand breaks which is not linked to cell lysis. A mechanistic study in freshly isolated rat hepatocytes

artículo científico publicado en 1995

PDGF receptor signaling networks in normal and cancer cells

artículo científico

PDGF-D expression is down-regulated by TGFβ in fibroblasts

artículo científico publicado en 2014

PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase

artículo científico publicado en 2017

PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations

artículo científico publicado en 2013

PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib

artículo científico publicado en 2015

PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies

artículo científico publicado en 2011

Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors

artículo científico publicado en 2010

Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins

artículo científico publicado en 2004

Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis

artículo científico publicado en 2011

Platelet-derived growth factors and their receptors in normal and malignant hematopoiesis

artículo científico publicado en 2012

Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways

artículo científico publicado en 2012

Review of current classification, molecular alterations, and tyrosine kinase inhibitor therapies in myeloproliferative disorders with hypereosinophilia

artículo científico publicado en 2013

Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation

artículo científico publicado en 2000

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma

artículo científico publicado en 2007

Scleroderma

artículo científico publicado en 2009

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

artículo científico publicado en 2017

The HMG box transcription factor HBP1: a cell cycle inhibitor at the crossroads of cancer signaling pathways

scientific article published on 25 January 2019

The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway

artículo científico publicado en 2014

The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation

artículo científico publicado en 2009

The gene expression profile of PDGF-treated neural stem cells corresponds to partially differentiated neurons and glia

artículo científico publicado en 2006

The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells

artículo científico publicado en 2012

The t(11;19)(q23;p13) fusing MLL with MYO1F is recurrent in infant acute myeloid leukemias

artículo científico publicado en 2011

The t(1;9)(p34;q34) fusing ABL1 with SFPQ, a pre-mRNA processing gene, is recurrent in acute lymphoblastic leukemias.

artículo científico publicado en 2011

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors

artículo científico publicado en 2009

The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.

artículo científico publicado en 2014

Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms

artículo científico publicado en 2013

Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

artículo científico publicado en 2010

Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies

artículo científico

Lista de obras de Jean-Baptiste Demoulin

A minimal connected network of transcription factors regulated in human tumors and its application to the quest for universal cancer biomarkers

ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines

ABCB1 1199G>A polymorphism (rs2229109) affects the transport of imatinib, nilotinib and dasatinib.

Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota.

Autoinhibition of the platelet-derived growth factor beta-receptor tyrosine kinase by its C-terminal tail.

CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I.

Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway

Critical role of the platelet-derived growth factor receptor (PDGFR) beta transmembrane domain in the TEL-PDGFRbeta cytosolic oncoprotein

Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9

ETV6-PDGFRB and FIP1L1-PDGFRA stimulate human hematopoietic progenitor cell proliferation and differentiation into eosinophils: the role of nuclear factor-κB.

FOXO transcription factors in cancer development and therapy

Functional defect caused by the 4544G>A SNP in ABCC2: potential impact for drug cellular disposition

Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor

Global microRNA profiling of well-differentiated small intestinal neuroendocrine tumors.

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation

Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling

Impact of ABCB1 1236C > T-2677G > T-3435C > T polymorphisms on the anti-proliferative activity of imatinib, nilotinib, dasatinib and ponatinib

Inflammation-induced cholestasis in cancer cachexia

Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

JAK2, the JAK2 V617F mutant and cytokine receptors.

KANK1, a candidate tumor suppressor gene, is fused to PDGFRB in an imatinib-responsive myeloid neoplasm with severe thrombocythemia

Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis

Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF.

MAP kinase activation by interleukin-9 in lymphoid and mast cell lines

Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.

New insights into the mechanisms of hematopoietic cell transformation by activated receptor tyrosine kinases

No PDGF receptor signal in pericytes without endosialin?

Novel COL4A1-VEGFD gene fusion in myofibroma

Novel head-to-head gene fusion of MLL with ZC3H13 in a JAK2 V617F-positive patient with essential thrombocythemia without blast cells

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes

Oxidative DNA damage by t-butyl hydroperoxide causes DNA single strand breaks which is not linked to cell lysis. A mechanistic study in freshly isolated rat hepatocytes

PDGF receptor signaling networks in normal and cancer cells

PDGF-D expression is down-regulated by TGFβ in fibroblasts

PDGF-induced fibroblast growth requires monounsaturated fatty acid production by stearoyl-CoA desaturase

PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations

PDGFRB mutants found in patients with familial infantile myofibromatosis or overgrowth syndrome are oncogenic and sensitive to imatinib

PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies

Paraneoplastic antigen Ma2 autoantibodies as specific blood biomarkers for detection of early recurrence of small intestine neuroendocrine tumors

Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins

Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis

Platelet-derived growth factors and their receptors in normal and malignant hematopoiesis

Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways

Review of current classification, molecular alterations, and tyrosine kinase inhibitor therapies in myeloproliferative disorders with hypereosinophilia

Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation

SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma

Scleroderma

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

The HMG box transcription factor HBP1: a cell cycle inhibitor at the crossroads of cancer signaling pathways

The expression of the tumour suppressor HBP1 is down-regulated by growth factors via the PI3K/PKB/FOXO pathway

The fusion proteins TEL-PDGFRbeta and FIP1L1-PDGFRalpha escape ubiquitination and degradation

The gene expression profile of PDGF-treated neural stem cells corresponds to partially differentiated neurons and glia

The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cells

The t(11;19)(q23;p13) fusing MLL with MYO1F is recurrent in infant acute myeloid leukemias

The t(1;9)(p34;q34) fusing ABL1 with SFPQ, a pre-mRNA processing gene, is recurrent in acute lymphoblastic leukemias.

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors

The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.

Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms

Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies