Lista de obras - Ian G. Ganley - Dominio Público Uruguay

A comparative map of macroautophagy and mitophagy in the vertebrate eye

scientific article published on 20 February 2019

A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling

artículo científico publicado en 2006

A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

artículo científico publicado en 2008

ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A.

artículo científico publicado en 2018

Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity

artículo científico publicado en 2020

Autophagosome maturation and lysosomal fusion

artículo científico

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

artículo científico publicado en 2014

Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells

artículo científico publicado en 2006

Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys

artículo científico publicado en 2019

Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling

artículo científico publicado en 2006

Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells

artículo científico publicado en 2013

DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron depletion

artículo científico publicado en 2022

Determination of Cellular Phosphatidylinositol-3-phosphate (PI3P) Levels Using a Fluorescently Labelled Selective PI3P Binding Domain (PX).

artículo científico publicado en 2016

Determination of VPS34/PIK3C3 Activity in vitro Utilising 32P-γATP.

artículo científico publicado en 2016

Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest

artículo científico publicado en 2011

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6.

artículo científico publicado en 2013

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

artículo científico publicado en 2015

Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1

scientific article published on 12 November 2021

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells

artículo científico publicado en 2016

Investigating Mitophagy and Mitochondrial Morphology In Vivo Using mito-QC: A Comprehensive Guide

artículo científico publicado en 2019

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

artículo científico publicado en 2018

Life in lights: Tracking mitochondrial delivery to lysosomes in vivo

artículo científico publicado en 2016

Loss of iron triggers PINK1/Parkin-independent mitophagy

artículo científico publicado en 2013

MTOR, PIK3C3, and autophagy: Signaling the beginning from the end.

artículo científico publicado en 2015

Mammalian mitophagy - from in vitro molecules to in vivo models.

artículo científico publicado en 2017

Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

scientific article published on 01 August 2018

Outstanding Questions in Mitophagy: What We Do and Do Not Know

scientific article published on 09 July 2019

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

artículo científico publicado en 2015

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

artículo científico publicado en 2015

Phosphorylation of Parkin at serine 65 is essential for its activation

artículo científico publicado en 2018

Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading

artículo científico publicado en 2019

RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins

artículo científico publicado en 2011

RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36

scientific journal article

Rab9 GTPase regulates late endosome size and requires effector interaction for its stability

artículo científico publicado en 2004

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

artículo científico publicado en 2012

Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport

artículo científico publicado en 2003

Semi-automated quantitation of mitophagy in cells and tissues

scientific article published on 13 December 2019

Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy

article

The ULK1 complex: sensing nutrient signals for autophagy activation.

artículo científico

The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets

artículo científico publicado en 2020

The mammalian ULK1 complex and autophagy initiation.

artículo científico publicado en 2017

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

artículo científico publicado en 2017

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

artículo científico publicado en 2009

mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival

artículo científico publicado en 2015

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

artículo científico publicado en 2016

p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

artículo científico publicado en 2013

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Ian G. Ganley

A comparative map of macroautophagy and mitophagy in the vertebrate eye

A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling

A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A.

Aberrant autophagosome formation occurs upon small molecule inhibition of ULK1 kinase activity

Autophagosome maturation and lysosomal fusion

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells

Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys

Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling

Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells

DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron depletion

Determination of Cellular Phosphatidylinositol-3-phosphate (PI3P) Levels Using a Fluorescently Labelled Selective PI3P Binding Domain (PX).

Determination of VPS34/PIK3C3 Activity in vitro Utilising 32P-γATP.

Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6.

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1

Guidelines for the use and interpretation of assays for monitoring autophagy

Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells

Investigating Mitophagy and Mitochondrial Morphology In Vivo Using mito-QC: A Comprehensive Guide

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

Life in lights: Tracking mitochondrial delivery to lysosomes in vivo

Loss of iron triggers PINK1/Parkin-independent mitophagy

MTOR, PIK3C3, and autophagy: Signaling the beginning from the end.

Mammalian mitophagy - from in vitro molecules to in vivo models.

Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Outstanding Questions in Mitophagy: What We Do and Do Not Know

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

Phosphorylation of Parkin at serine 65 is essential for its activation

Proinflammatory NFkB signalling promotes mitochondrial dysfunction in skeletal muscle in response to cellular fuel overloading

RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins

RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36

Rab9 GTPase regulates late endosome size and requires effector interaction for its stability

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport

Semi-automated quantitation of mitophagy in cells and tissues

Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy

The ULK1 complex: sensing nutrient signals for autophagy activation.

The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets

The mammalian ULK1 complex and autophagy initiation.

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)