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Lista de obras de Patrick M. Kochanek

"Lost in translation?" Noninvasive cerebral monitoring after cardiac arrest

artículo científico publicado en 2011

2',3'-cAMP, 3'-AMP, 2'-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors.

artículo científico publicado en 2014

72-kDa heat shock protein and mRNA expression after controlled cortical impact injury with hypoxemia in rats

artículo científico publicado en 1998

A critical problem begging for new insight and new therapies

artículo científico publicado en 2009

A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ ⬇️

artículo científico publicado el 1 de mayo de 2003

A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury

artículo científico publicado en 2007

A high-throughput screening assay of ascorbate in brain samples

artículo científico publicado en 2011

A mitochondrial pathway for biosynthesis of lipid mediators

artículo científico publicado en 2014

A model of diffuse traumatic brain injury in the immature rat.

artículo científico publicado en 1996

A new roadmap for mechanical circulatory support in children

artículo científico publicado en 2013

A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy

artículo científico publicado en 2011

A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation

artículo científico publicado en 1998

A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest.

artículo científico publicado en 2010

A tribute to Peter J. Safar, MD.

artículo científico publicado en 2003

Acute CSF interleukin-6 trajectories after TBI: associations with neuroinflammation, polytrauma, and outcome

artículo científico publicado en 2014

Acute etomidate treatment reduces cognitive deficits and histopathology in rats with traumatic brain injury

artículo científico publicado en 2003

Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats

artículo científico publicado en 2002

Adenosine A1 receptor activation as a brake on the microglial response after experimental traumatic brain injury in mice

artículo científico publicado en 2010

Adenosine A1 receptor gene variants associated with post-traumatic seizures after severe TBI.

artículo científico publicado en 2010

Adenosine by aortic flush fails to augment the brain preservation effect of mild hypothermia during exsanguination cardiac arrest in dogs - an exploratory study

scientific article published on 01 March 2000

Adenovirus-mediated transfer and expression of beta-gal in injured hippocampus after traumatic brain injury in mice

artículo científico publicado en 2001

Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology

artículo científico publicado en 2002

Alterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury.

artículo científico publicado en 2003

An acute inflammatory response to the use of granulocyte colony-stimulating factor to prevent infections in patients with brain injury: what about the brain?

artículo científico publicado en 1999

Anthraquinone-2-sulfonic acid (AQ2S) is a novel neurotherapeutic agent

artículo científico publicado en 2013

Apoptotic interactions of cytochrome c: redox flirting with anionic phospholipids within and outside of mitochondria

artículo científico publicado en 2006

Asphyxial cardiac arrest from drowning: giving E-CPR the cold shoulder

artículo científico publicado en 2015

Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children

artículo científico publicado en 2002

Assessment of the delta opioid agonist DADLE in a rat model of lethal hemorrhage treated by emergency preservation and resuscitation

artículo científico publicado en 2008

Assessment of the effect of 2-chloroadenosine in normal rat brain using spin-labeled MRI measurement of perfusion

artículo científico publicado en 2001

Astrocytes are the major source of nerve growth factor upregulation following traumatic brain injury in the rat.

artículo científico publicado en 1998

Augmented neuronal death in CA3 hippocampus following hyperventilation early after controlled cortical impact.

artículo científico publicado en 1998

Authors' response to letter to the editor, "Effect of a single dose of propofol and lack of dextrose administration in a child with mitochondrial disease--a case report".

artículo científico publicado en 2014

Automated detection and characterization of SPIO-labeled cells and capsules using magnetic field perturbations

artículo científico publicado en 2011

Autophagy in acute brain injury: feast, famine, or folly?

artículo científico publicado en 2010

Autophagy is Increased after Traumatic Brain Injury in Mice and is Partially Inhibited by the Antioxidant γ-glutamylcysteinyl Ethyl Ester

article

Bakken Lecture: the brain, the heart, and therapeutic hypothermia

artículo científico publicado en 2009

Bench-to-bedside review: Apoptosis/programmed cell death triggered by traumatic brain injury

artículo científico publicado en 2004

Biochemical markers of brain injury: could they be used as diagnostic adjuncts in cases of inflicted traumatic brain injury?

artículo científico publicado en 2004

Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury

artículo científico publicado en 2011

Blood brain barrier is impermeable to solutes and permeable to water after experimental pediatric cardiac arrest.

artículo científico publicado en 2014

Blood-brain barrier integrity in a rat model of emergency preservation and resuscitation.

artículo científico publicado en 2009

Brain resuscitation in the drowning victim

artículo científico publicado en 2012

Brain tissue oxygen monitoring after severe traumatic brain injury in children: relationship to outcome and association with other clinical parameters

artículo científico publicado en 2012

Brain tissue oxygen monitoring identifies cortical hypoxia and thalamic hyperoxia after experimental cardiac arrest in rats.

artículo científico publicado en 2013

CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI.

artículo científico publicado en 2011

Cardiac arrest and therapeutic hypothermia decrease isoform-specific cytochrome P450 drug metabolism.

artículo científico publicado en 2011

Cardiac arrest in children

artículo científico publicado en 2010

Cardiolipin-Dependent Mitophagy Guides Outcome after Traumatic Brain Injury

scientific article published on 09 January 2019

Caspase-3 mediated neuronal death after traumatic brain injury in rats

scientific article published on 01 February 2000

Caspase-8 expression and proteolysis in human brain after severe head injury.

artículo científico publicado en 2003

Cerebral blood flow at one year after controlled cortical impact in rats: assessment by magnetic resonance imaging

artículo científico publicado en 2002

Cerebral blood flow changes after brain injury in human amyloid-beta knock-in mice

artículo científico publicado en 2013

Cerebral blood flow promotion after prolonged cardiac arrest

scientific article published on 01 August 2000

Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin-labeled MRI.

artículo científico publicado en 2001

Cerebrospinal Fluid Markers of Macrophage and Lymphocyte Activation After Traumatic Brain Injury in Children

artículo científico publicado en 2015

Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans

artículo científico publicado en 1997

Cerebrospinal fluid and plasma nitrite and nitrate concentrations after head injury in humans

article

Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injury

artículo científico publicado en 2007

Cerebrospinal fluid levels of high-mobility group box 1 and cytochrome C predict outcome after pediatric traumatic brain injury

artículo científico publicado en 2012

Cerebrospinal fluid mitochondrial DNA: a novel DAMP in pediatric traumatic brain injury

artículo científico publicado en 2014

Cerebrospinal fluid procalcitonin and severe traumatic brain injury in children

artículo científico publicado en 2002

Cerebrovascular response in children following severe traumatic brain injury

scientific article published on 11 May 2011

Changes in expression of amyloid precursor protein and interleukin-1beta after experimental traumatic brain injury in rats

artículo científico publicado en 2002

Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging

artículo científico publicado en 2005

Clinical trials in head injury

artículo científico publicado en 2002

Cold aortic flush and chest compressions enable good neurologic outcome after 15 mins of ventricular fibrillation in cardiac arrest in pigs

artículo científico publicado en 2010

Comparison of seven anesthetic agents on outcome after experimental traumatic brain injury in adult, male rats

artículo científico publicado en 2006

Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats

artículo científico publicado en 2002

Critical mechanisms of secondary damage after inflicted head injury in infants and children

artículo científico publicado en 2002

Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation

artículo científico publicado en 2006

Cytochrome c, a Biomarker of Apoptosis, is Increased in Cerebrospinal Fluid from Infants with Inflicted Brain Injury from Child Abuse

article

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

artículo científico publicado en 2009

Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion

artículo científico publicado en 2014

Deep hypothermia attenuates microglial proliferation independent of neuronal death after prolonged cardiac arrest in rats.

artículo científico publicado en 2009

Delayed, spontaneous hypothermia reduces neuronal damage after asphyxial cardiac arrest in rats

artículo científico publicado en 2000

Developing cooling strategies targeting the heart in adults and children

artículo científico publicado en 2012

Differences in medical therapy goals for children with severe traumatic brain injury-an international study

artículo científico publicado en 2013

Disruption of Bax protein prevents neuronal cell death but produces cognitive impairment in mice following traumatic brain injury.

artículo científico publicado en 2008

Early cerebrovascular response to head injury in immature and mature rats

artículo científico publicado en 1994

Early neuropathologic effects of mild or moderate hypoxemia after controlled cortical impact injury in rats

artículo científico publicado en 1997

Early perfusion after controlled cortical impact in rats: quantification by arterial spin-labeled MRI and the influence of spin-lattice relaxation time heterogeneity

artículo científico publicado en 1999

Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats

artículo científico publicado en 1990

Effect of a single dose of propofol and lack of dextrose administration in a child with mitochondrial disease: a case report

artículo científico publicado en 2013

Effect of administration of neuromuscular blocking agents in children with severe traumatic brain injury on acute complication rates and outcomes: a secondary analysis from a randomized, controlled trial of therapeutic hypothermia

artículo científico publicado en 2015

Effect of hyperoxia on resuscitation of experimental combined traumatic brain injury and hemorrhagic shock in mice

artículo científico publicado en 2013

Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury

artículo científico publicado en 2002

Effect of neutropenia and granulocyte colony stimulating factor-induced neutrophilia on blood-brain barrier permeability and brain edema after traumatic brain injury in rats

artículo científico publicado en 2000

Effect of short periods of normobaric hyperoxia on local brain tissue oxygenation and cerebrospinal fluid oxidative stress markers in severe traumatic brain injury

artículo científico publicado en 2009

Effect of traumatic brain injury in mice deficient in intercellular adhesion molecule-1: assessment of histopathologic and functional outcome

artículo científico publicado en 1999

Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury--Results From an Automated Data Collection System Time-Synched to Drug Administration

artículo científico publicado en 2015

Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system.

artículo científico publicado en 2007

Effects of neutropenia on edema, histology, and cerebral blood flow after traumatic brain injury in rats

artículo científico publicado en 1994

Effects of post-injury hypothermia and nerve growth factor infusion on antioxidant enzyme activity in the rat: implications for clinical therapies

artículo científico publicado en 2004

Electron spin resonance measure of brain antioxidant activity during ischemia/reperfusion

artículo científico publicado en 1998

Emergency preservation and resuscitation improve survival after 15 minutes of normovolemic cardiac arrest in pigs

artículo científico publicado en 2007

Emergency preservation and resuscitation with profound hypothermia, oxygen, and glucose allows reliable neurological recovery after 3 h of cardiac arrest from rapid exsanguination in dogs

artículo científico publicado en 2007

Emerging therapies in traumatic brain injury

artículo científico publicado en 2015

Endothelin-1 Is Increased in Cerebrospinal Fluid and Associated with Unfavorable Outcomes in Children after Severe Traumatic Brain Injury ⬇️

artículo científico publicado el 17 de septiembre de 2010

Energy expenditure in children after severe traumatic brain injury

artículo científico publicado en 2014

Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS.

artículo científico publicado en 2005

Evaluation of autophagy using mouse models of brain injury

artículo científico publicado en 2009

Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse

artículo científico publicado en 2001

Experimental model of pediatric asphyxial cardiopulmonary arrest in rats

artículo científico publicado en 2004

Expression of the 2′,3′‐cAMP‐adenosine pathway in astrocytes and microglia ⬇️

artículo científico publicado el 12 de agosto de 2011

Exsanguination cardiac arrest in rats treated by 60 min, but not 75 min, emergency preservation and delayed resuscitation is associated with intact outcome

artículo científico publicado en 2007

Extracorporeal versus conventional cardiopulmonary resuscitation after ventricular fibrillation cardiac arrest in rats: a feasibility trial

artículo científico publicado en 2013

F2-isoprostane and neuron-specific enolase in cerebrospinal fluid after severe traumatic brain injury in infants and children

artículo científico publicado en 2003

Fever control and application of hypothermia using intravenous cold saline.

artículo científico publicado en 2012

Finding a faster and safer way to "catch a cold" after cardiac arrest: we may be getting closer

scientific article published on 30 June 2014

Global and Regional Derangements of Cerebral Blood Flow and Diffusion Magnetic Resonance Imaging after Pediatric Cardiac Arrest

artículo científico publicado en 2015

Global and regional differences in cerebral blood flow after asphyxial versus ventricular fibrillation cardiac arrest in rats using ASL-MRI

artículo científico publicado en 2014

Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition

artículo científico publicado en 2012

Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents. Chapter 1: Introduction.

artículo científico publicado en 2003

HBO: It's not ready for prime time for the treatment of acute central nervous system trauma.

artículo científico publicado en 2001

Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in mice

artículo científico publicado en 2014

Histopathologic response of the immature rat to diffuse traumatic brain injury

artículo científico publicado en 2001

How low can you go? Blood pressure control after intracranial hemorrhage

artículo científico publicado en 1999

Hypothermia and hemostasis in severe trauma: A new crossroads workshop report

artículo científico publicado en 2012

Hypothermia and hyperthermia in children after resuscitation from cardiac arrest

artículo científico publicado en 2000

Hypothermia attenuates the normal increase in interleukin 1 beta RNA and nerve growth factor following traumatic brain injury in the rat

artículo científico publicado en 1995

Hypothermia decreases cerebrospinal fluid asymmetric dimethylarginine levels in children with traumatic brain injury.

artículo científico publicado en 2013

Hypothermic therapies targeting brain and spinal cord injury. Introduction

artículo científico publicado en 2009

IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study.

artículo científico publicado en 2014

Identification of inflicted traumatic brain injury in well-appearing infants using serum and cerebrospinal markers: a possible screening tool

artículo científico publicado en 2006

Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury

artículo científico publicado en 2007

Immunohistochemical analysis of histone H3 acetylation and methylation--evidence for altered epigenetic signaling following traumatic brain injury in immature rats

artículo científico publicado en 2006

Improving outcomes from resuscitation: from hypertension and hemodilution to therapeutic hypothermia to H2.

artículo científico publicado en 2014

In quest of the optimal cooling device: isn't faster "too fast"?

artículo científico publicado en 2008

In response to comments on IL-1β associations with posttraumatic epilepsy development: a genetics and biomarker cohort study

artículo científico publicado en 2014

Increased CSF Concentrations of Myelin Basic Protein After TBI in Infants and Children: Absence of Significant Effect of Therapeutic Hypothermia ⬇️

artículo científico publicado el 1 de diciembre de 2012

Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: association with severity of injury and excitotoxicity

artículo científico publicado en 2001

Increased adrenomedullin in cerebrospinal fluid after traumatic brain injury in infants and children

artículo científico publicado en 2001

Increased phosphorylation of protein kinase B and related substrates after traumatic brain injury in humans and rats

artículo científico publicado en 2005

Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury

article

Induced hyperthermia exacerbates neurologic neuronal histologic damage after asphyxial cardiac arrest in rats

artículo científico publicado en 2003

Inducible nitric oxide synthase expression in cerebrovascular smooth muscle and neutrophils after traumatic brain injury in immature rats

scientific article published on 01 May 1996

Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice

artículo científico publicado en 1999

Induction of profound hypothermia for emergency preservation and resuscitation allows intact survival after cardiac arrest resulting from prolonged lethal hemorrhage and trauma in dogs

artículo científico publicado en 2006

Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children.

artículo científico publicado en 2004

Influence of PARP-1 polymorphisms in patients after traumatic brain injury

artículo científico publicado en 2010

Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway

artículo científico publicado en 2004

Interactive roles of CD73 and tissue nonspecific alkaline phosphatase in the renal vascular metabolism of 5'-AMP.

artículo científico publicado en 2014

Interleukin 6 and apolipoprotein E as predictors of acute brain dysfunction and survival in critical care patients.

artículo científico publicado en 2014

Interleukin-1 receptor antagonist suppresses neurotrophin response in injured rat brain

scientific article published on 01 January 1996

Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children.

artículo científico publicado en 1997

Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury

scientific article published on 01 April 2000

Interstitial adenosine, inosine, and hypoxanthine are increased after experimental traumatic brain injury in the rat.

artículo científico publicado en 1998

Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury

artículo científico publicado en 2001

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress

artículo científico publicado en 2003

Intracranial monitoring and continuous data collection

scientific article published on 01 November 2012

Intracranial pressure-monitoring systems in children with traumatic brain injury: combining therapeutic and diagnostic tools

artículo científico publicado en 2011

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite

artículo científico publicado en 2002

Intraperitoneal, but not enteric, adenosine administration improves survival after volume-controlled hemorrhagic shock in rats

artículo científico publicado en 2001

Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro

artículo científico publicado en 2015

Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injury

artículo científico publicado en 2006

Isoflurane improves long-term neurologic outcome versus fentanyl after traumatic brain injury in rats

artículo científico publicado en 2000

It might be time to let cooler heads prevail after mild traumatic brain injury or concussion

artículo científico publicado en 2015

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

artículo científico publicado en 2012

Long-Term Deficits in Cortical Circuit Function after Asphyxial Cardiac Arrest and Resuscitation in Developing Rats

artículo científico publicado en 2017

Long-term dysfunction following diffuse traumatic brain injury in the immature rat.

artículo científico publicado en 2000

MRI assessment of cerebral blood flow after experimental traumatic brain injury combined with hemorrhagic shock in mice

artículo científico publicado en 2012

Magnetic resonance imaging assessment of macrophage accumulation in mouse brain after experimental traumatic brain injury

artículo científico publicado en 2009

Magnetic resonance imaging assessment of regional cerebral blood flow after asphyxial cardiac arrest in immature rats

artículo científico publicado en 2008

Making an IMPACT in traumatic brain injury research

artículo científico publicado en 2013

Management of pulmonary barotrauma by extracorporeal membrane oxygenation, apnea, and lung rest

scientific article published on 01 May 1988

Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations

artículo científico publicado en 2012

Marked gender effect on lipid peroxidation after severe traumatic brain injury in adult patients

artículo científico publicado en 2004

Mass critical care for children: implications for adult critical care

artículo científico publicado en 2011

Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli

artículo científico publicado en 2009

Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis

artículo científico publicado en 2008

Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury

artículo científico publicado en 2010

Microglial depletion using intrahippocampal injection of liposome-encapsulated clodronate in prolonged hypothermic cardiac arrest in rats.

artículo científico publicado en 2011

Mild hypothermia alters midazolam pharmacokinetics in normal healthy volunteers.

artículo científico publicado en 2010

Mild hypothermia decreases fentanyl and midazolam steady-state clearance in a rat model of cardiac arrest ⬇️

artículo científico publicado el 1 de abril de 2012

Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses

artículo científico publicado en 2003

Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs

scientific article published on 01 October 2004

Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs

artículo científico publicado en 2005

Minocycline attenuates brain tissue levels of TNF-α produced by neurons after prolonged hypothermic cardiac arrest in rats

artículo científico publicado en 2014

Minocycline reduces neuronal death and attenuates microglial response after pediatric asphyxial cardiac arrest

artículo científico publicado en 2009

Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids

artículo científico publicado en 2012

Moderate hypothermia may be detrimental after traumatic brain injury in fentanyl-anesthetized rats

artículo científico publicado en 2003

Moderate hypothermia prevents cardiac arrest-mediated suppression of drug metabolism and induction of interleukin-6 in rats.

artículo científico publicado en 2009

Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature rat.

artículo científico publicado en 2012

Motor and cognitive functional deficits following diffuse traumatic brain injury in the immature rat

artículo científico publicado en 1997

Multiplex Assessment of Cytokine and Chemokine Levels in Cerebrospinal Fluid following Severe Pediatric Traumatic Brain Injury: Effects of Moderate Hypothermia

article

Multiplex assessment of serum biomarker concentrations in well-appearing children with inflicted traumatic brain injury

artículo científico publicado en 2009

Murine orthostatic response during prolonged vertical studies: effect on cerebral blood flow measured by arterial spin-labeled MRI.

artículo científico publicado en 2005

Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic.

artículo científico publicado en 2010

Neuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children

artículo científico publicado en 2002

Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury

artículo científico publicado en 2007

Neutrophil accumulation after traumatic brain injury in rats: comparison of weight drop and controlled cortical impact models

artículo científico publicado en 1994

Neutrophils do not mediate blood-brain barrier permeability early after controlled cortical impact in rats

artículo científico publicado en 1999

Nifedipine in the treatment of a child with pulmonary hypertension associated with severe bronchopulmonary dysplasia

artículo científico publicado en 1986

One-year study of spatial memory performance, brain morphology, and cholinergic markers after moderate controlled cortical impact in rats

artículo científico publicado en 1999

Optimization of epoxyeicosatrienoic acid syntheses to test their effects on cerebral blood flow in vivo

scientific article published on 01 June 1995

Optimizing oxygenation and ventilation after cardiac arrest in "little adults"

artículo científico publicado en 2012

Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells.

artículo científico publicado en 2006

Oxidative lipidomics of apoptosis: quantitative assessment of phospholipid hydroperoxides in cells and tissues

artículo científico publicado en 2010

Oxidative lipidomics of programmed cell death

artículo científico publicado en 2008

Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates

scientific article published on 01 November 2000

PCCM 2014

scientific article published on 01 November 2014

Partial liquid ventilation combined with high frequency gas ventilation: clinical breakthrough or two treatments looking for a home?

artículo científico publicado en 1999

Pass the salt?

artículo científico publicado en 1998

Patterns of multiorgan dysfunction after pediatric drowning

artículo científico publicado en 2015

Pediatric Critical Care Medicine reaches another milestone

artículo científico publicado en 2012

Pediatric Critical Care Medicine: Re-tooling to accommodate growth and success while preserving excellence

scientific article published on 01 January 2011

Pediatric critical care medicine in Chinese--and other developments

scientific article published on 01 April 2002

Pediatric critical care medicine: planning for our research future

artículo científico publicado en 2003

Pediatric neurointensive care: 2008 update for the Rogers' Textbook of Pediatric Intensive Care

artículo científico publicado en 2009

Pediatric traumatic brain injury in 2012: the year with new guidelines and common data elements

artículo científico publicado en 2013

Pediatric traumatic brain injury is inconsistently regionalized in the United States

artículo científico publicado en 2008

Pediatric traumatic brain injury: beyond the guidelines

artículo científico publicado en 2005

Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes

artículo científico publicado en 2013

Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup

artículo científico publicado en 2014

Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children

artículo científico publicado en 2017

Physiological assessment and control in studies evaluating central nervous system injury: should size matter?

artículo científico publicado en 2006

Platelet-activating factor antagonists do not attenuate delayed posttraumatic cerebral edema in rats

artículo científico publicado en 1991

Politics and hypothermia-what might they have in common? Editorial comment on silasi and colbourne, 2011

artículo científico publicado en 2012

Polynitroxyl albumin and albumin therapy after pediatric asphyxial cardiac arrest: effects on cerebral blood flow and neurologic outcome

artículo científico publicado en 2011

Polynitroxylated pegylated hemoglobin: a novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice

artículo científico publicado en 2011

Polynitroxylated-pegylated hemoglobin attenuates fluid requirements and brain edema in combined traumatic brain injury plus hemorrhagic shock in mice

artículo científico publicado en 2013

Postcardiac arrest syndrome: focus on the brain

artículo científico publicado en 2009

Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro

artículo científico publicado en 2016

Progress Amidst Some Anticipated Growing Pains for PCCM

artículo científico publicado en 2013

Prolonged deep hypothermic circulatory arrest in rats can be achieved without cognitive deficits.

artículo científico publicado en 2007

Promising strategies to minimize secondary brain injury after head trauma

artículo científico publicado en 2003

Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia

artículo científico publicado en 2006

Protein nitration and poly-ADP-ribosylation in brain after rapid exsanguination cardiac arrest in a rat model of emergency preservation and resuscitation

artículo científico publicado en 2008

Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans

artículo científico publicado en 2006

Publication of Cochrane Reviews in Critical Care Medicine and Pediatric Critical Care Medicine: guiding practice or duplicating the literature?

scientific article published on 01 July 2002

Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury.

artículo científico publicado en 2008

Quinolinic acid in the cerebrospinal fluid of children after traumatic brain injury

artículo científico publicado en 1999

Quo Vadis 2010? – Carpe Diem: Challenges and Opportunities in Pediatric Traumatic Brain Injury ⬇️

artículo científico publicado el 1 de enero de 2010

Regional brain injury on conventional and diffusion weighted MRI is associated with outcome after pediatric cardiac arrest

artículo científico publicado en 2013

Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury

scientific article published on 01 July 2002

Relationship between hyperglycemia and outcome in children with severe traumatic brain injury.

artículo científico publicado en 2012

Relationship of intracranial pressure and cerebral perfusion pressure with outcome in young children after severe traumatic brain injury

artículo científico publicado en 2010

Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia

artículo científico publicado en 2004

Repetitive Mild Traumatic Brain Injury in the Developing Brain: Effects on Long-Term Functional Outcome and Neuropathology

artículo científico publicado en 2015

Resuscitation of traumatic brain injury and hemorrhagic shock with polynitroxylated albumin, hextend, hypertonic saline, and lactated Ringer's: Effects on acute hemodynamics, survival, and neuronal death in mice

artículo científico publicado en 2009

Risk factors for mortality in children with abusive head trauma.

artículo científico publicado en 2012

Role of 2',3'-cyclic nucleotide 3'-phosphodiesterase in the renal 2',3'-cAMP-adenosine pathway

artículo científico publicado en 2014

Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney.

artículo científico publicado en 2012

Role of CNPase in the oligodendrocytic extracellular 2',3'-cAMP-adenosine pathway

scientific article published on 06 August 2013

Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats

artículo científico publicado en 2013

Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis

artículo científico publicado en 2007

Serum D-dimer concentrations are increased after pediatric traumatic brain injury

artículo científico publicado en 2014

Serum S100B concentrations are increased after closed head injury in children: a preliminary study

artículo científico publicado en 2002

Serum amyloid A is increased in children with abusive head trauma: a gel-based proteomic analysis

artículo científico publicado en 2014

Serum biomarkers after traumatic and hypoxemic brain injuries: insight into the biochemical response of the pediatric brain to inflicted brain injury

artículo científico publicado en 2006

Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*.

artículo científico publicado en 2014

Severe controlled cortical impact in rats: assessment of cerebral edema, blood flow, and contusion volume.

artículo científico publicado en 1995

Should we add stem cells to the code cart in resuscitation of heatstroke?

artículo científico publicado en 2005

Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65.

artículo científico publicado en 2015

Soluble adhesion molecules in CSF are increased in children with severe head injury

artículo científico publicado en 1998

Some historic firsts for Pediatric Critical Care Medicine

artículo científico publicado en 2001

Specialty neurointensive care--Is it just a name or a way of life?

artículo científico publicado en 2001

Starving neurons show sex difference in autophagy.

artículo científico publicado en 2008

Subarachnoid hemorrhage, systemic immune response syndrome, and MODS: is there cross-talk between the injured brain and the extra-cerebral organ systems? Multiple organ dysfunction syndrome

artículo científico publicado en 1999

Survival without brain damage after clinical death of 60-120 mins in dogs using suspended animation by profound hypothermia

artículo científico publicado en 2003

Suspended animation can allow survival without brain damage after traumatic exsanguination cardiac arrest of 60 minutes in dogs

artículo científico publicado en 2004

Systemic hypothermia, but not regional gut hypothermia, improves survival from prolonged hemorrhagic shock in rats

artículo científico publicado en 2002

Targeting therapeutic hypothermia in neonatal resuscitation and beyond: it is time to phenotype

scientific article published on 23 January 2014

Thalamocortical dysfunction and thalamic injury after asphyxial cardiac arrest in developing rats.

artículo científico publicado en 2012

The antioxidant enzymes glutathione peroxidase and catalase increase following traumatic brain injury in the rat.

artículo científico publicado en 1997

The brain in vivo expresses the 2',3'-cAMP-adenosine pathway.

artículo científico publicado en 2012

The effect of brain temperature on acute inflammation after traumatic brain injury in rats

artículo científico publicado en 1997

The far-reaching scope of neuroinflammation after traumatic brain injury

artículo científico publicado en 2017

The incredible career of Peter J. Safar, MD: the Michelangelo of acute medicine

artículo científico publicado en 2004

The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice

artículo científico publicado en 2015

The potential for bio-mediators and biomarkers in pediatric traumatic brain injury and neurocritical care

artículo científico publicado en 2013

The simple model versus the super model: translating experimental traumatic brain injury research to the bedside.

artículo científico publicado en 2001

The utility of near infrared spectroscopy in detecting intracranial hemorrhage in children.

artículo científico publicado en 2012

Therapeutic Hypothermia Decreases Phenytoin Elimination in Children with Traumatic Brain Injury* ⬇️

artículo científico publicado el 1 de octubre de 2013

Therapeutic Hypothermia on Its 10th Anniversary: Is it Time to Turn the Thermostat Down?

artículo científico publicado en 2012

Therapeutic hypothermia after cardiac arrest

scientific article published on 01 February 2002

Therapeutic hypothermia for severe traumatic brain injury

artículo científico publicado en 2003

Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children

artículo científico publicado en 2009

Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model

artículo científico publicado en 2006

Therapeutic hypothermia: applications in pediatric cardiac arrest.

artículo científico publicado en 2009

Therapeutic hypothermia: the Safar vision

scientific article published on March 2009

Time course analysis of hippocampal nerve growth factor and antioxidant enzyme activity following lateral controlled cortical impact brain injury in the rat.

artículo científico publicado en 2004

Titrating oxygen during and after cardiopulmonary resuscitation

artículo científico publicado en 2010

Trajectory analysis of serum biomarker concentrations facilitates outcome prediction after pediatric traumatic and hypoxemic brain injury

artículo científico publicado en 2010

Transgenic mice that overexpress the anti-apoptotic Bcl-2 protein have improved histological outcome but unchanged behavioral outcome after traumatic brain injury

artículo científico publicado en 2006

Treatment of traumatic brain injury with moderate hypothermia.

artículo científico publicado en 1997

Unique brain region-dependent cytokine signatures after prolonged hypothermic cardiac arrest in rats.

artículo científico publicado en 2014

Unusual peroxidase activity of polynitroxylated pegylated hemoglobin: elimination of H(2)O(2) coupled with intramolecular oxidation of nitroxides

artículo científico publicado en 2010

Upregulation of nerve growth factor following cortical trauma.

artículo científico publicado en 1994

Urinary S100B concentrations are increased after brain injury in children: A preliminary study

artículo científico publicado en 2006

Variable neuroendocrine-immune dysfunction in individuals with unfavorable outcome after severe traumatic brain injury.

artículo científico publicado en 2014

Will the next breakthrough for neuroprotection after cardiac arrest come out of thin air?

artículo científico publicado en 2014

Winning the cold war: Inroads into implementation of mild hypothermia after cardiac arrest in adults from the European Resuscitation Council Hypothermia After Cardiac Arrest Registry Study Group*

artículo científico publicado en 2007

boc-Aspartyl(OMe)-fluoromethylketone attenuates mitochondrial release of cytochrome c and delays brain tissue loss after traumatic brain injury in rats

artículo científico publicado en 2006

α-Synuclein levels are elevated in cerebrospinal fluid following traumatic brain injury in infants and children: the effect of therapeutic hypothermia.

artículo científico publicado en 2010

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