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Lista de obras de Stephen Muench

A Tribute to Stephen Allan Baldwin

artículo científico publicado en 2015

A cryo-EM grid preparation device for time-resolved structural studies

artículo científico publicado en 2019

A method for detergent-free isolation of membrane proteins in their local lipid environment. ⬇️

artículo científico publicado en 2016

A reconstitution method for integral membrane proteins in hybrid lipid-polymer vesicles for enhanced functional durability ⬇️

artículo científico publicado en 2018

ALOX12 in human toxoplasmosis

artículo científico publicado en 2014

An introduction to sample preparation and imaging by cryo-electron microscopy for structural biology ⬇️

artículo científico publicado en 2016

Approaches to altering particle distributions in cryo-electron microscopy sample preparation ⬇️

scientific article published on 18 May 2018

Archazolid A binds to the equatorial region of the c-ring of the vacuolar H+-ATPase

artículo científico publicado en 2010

Artificial membranes for membrane protein purification, functionality and structure studies ⬇️

artículo científico publicado en 2016

AtSPX1 affects the AtPHR1 -DNA binding equilibrium by binding monomeric AtPHR1 in solution ⬇️

artículo científico publicado en 2017

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii ⬇️

artículo científico publicado en 2018

Cell-free expression and SMA copolymer encapsulation of a functional receptor tyrosine kinase disease variant, FGFR3-TACC3

Characterization of the flexibility of the peripheral stalk of prokaryotic rotary A-ATPases by atomistic simulations ⬇️

artículo científico publicado en 2016

Cloning, purification and preliminary crystallographic analysis of the Bacillus subtilis GTPase YphC-GDP complex ⬇️

artículo científico publicado en 2006

Conformational changes during human P2X7 receptor activation examined by structural modelling and cysteine-based cross-linking studies ⬇️

artículo científico publicado en 2016

Corrigendum to 'Methods to account for movement and flexibility in cryo-EM data processing' [Methods 100 (2016) 35-41]. ⬇️

artículo científico publicado en 2016

Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella

artículo científico publicado en 2020

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states ⬇️

artículo científico publicado en 2018

Cryo-electron microscopy of the vacuolar ATPase motor reveals its mechanical and regulatory complexity

artículo científico publicado en 2009

Crystallization and preliminary X-ray crystallographic studies on the class II cholesterol oxidase from Burkholderia cepacia containing bound flavin

artículo científico publicado en 2002

Delivery of antimicrobials into parasites

artículo científico publicado en 2003

Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase

artículo científico publicado en 2013

Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides

artículo científico publicado en 2013

Dimeric structures of quinol-dependent nitric oxide reductases (qNORs) revealed by cryo-electron microscopy

scientific article published on 28 August 2019

Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay

artículo científico publicado en 2013

Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human ⬇️

artículo científico publicado en 2015

Durable proteo-hybrid vesicles for the extended functional lifetime of membrane proteins in bionanotechnology ⬇️

artículo científico publicado en 2016

Durable vesicles for reconstitution of membrane proteins in biotechnology ⬇️

artículo científico publicado en 2017

Editorial ⬇️

artículo científico publicado en 2016

Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. ⬇️

artículo científico publicado en 2018

Everyone needs good neighbours - the intricate relationship between the acetylcholine-receptor channel and its membrane environment ⬇️

artículo científico publicado en 2017

Expression, purification and crystallization of the Plasmodium falciparum enoyl reductase

artículo científico publicado en 2003

Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase

artículo científico publicado en 2006

Extracellular and Luminal pH Regulation by Vacuolar H+-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes ⬇️

artículo científico publicado en 2016

Flexibility within the rotor and stators of the vacuolar H+-ATPase ⬇️

artículo científico publicado en 2013

Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site

artículo científico publicado en 2020

Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase

artículo científico publicado en 2010

Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans

artículo científico publicado en 2010

In situ formation of magnetopolymersomes via electroporation for MRI. ⬇️

artículo científico publicado en 2015

LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM

artículo científico publicado en 2019

Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host.

artículo científico publicado en 2005

Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium ⬇️

artículo científico publicado en 2015

Methods to account for movement and flexibility in cryo-EM data processing. ⬇️

artículo científico publicado en 2016

Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii

artículo científico publicado en 2013

Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds

artículo científico publicado en 2007

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections ⬇️

artículo científico publicado en 2016

No Longer Hidden Secrets of Proton Pumping: The Resolution Revolution Enlightens V-ATPases ⬇️

artículo científico publicado en 2018

Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers ⬇️

artículo científico publicado en 2014

Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway

artículo científico publicado en 2012

Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo

artículo científico publicado en 2008

PA1b inhibitor binding to subunits c and e of the vacuolar ATPase reveals its insecticidal mechanism ⬇️

artículo científico publicado en 2014

Pi sensing and signalling: from prokaryotic to eukaryotic cells ⬇️

artículo científico publicado en 2016

Replace, reuse, recycle: improving the sustainable use of phosphorus by plants ⬇️

artículo científico publicado en 2015

Rotating with the brakes on and other unresolved features of the vacuolar ATPase ⬇️

artículo científico publicado en 2016

Sample deposition onto cryo-EM grids: from sprays to jets and back

scientific article published on 25 March 2020

Spherical-supported membranes as platforms for screening against membrane protein targets. ⬇️

artículo científico publicado en 2018

Spiroindolone that inhibits PfATPase4 is a potent, cidal inhibitor of Toxoplasma gondii tachyzoites in vitro and in vivo

scientific article published on 23 December 2013

Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy

artículo científico publicado en 2020

Structural divergence of the rotary ATPases

scientific article published on 22 March 2011

Structure of the protective nematode protease complex H-gal-GP and its conservation across roundworm parasites

artículo científico publicado en 2020

Structure of the vacuolar H+-ATPase rotary motor reveals new mechanistic insights ⬇️

artículo científico publicado en 2015

Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists ⬇️

artículo científico publicado en 2016

Studies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agents

artículo científico publicado en 2007

Styrene maleic acid recovers proteins from mammalian cells and tissues while avoiding significant cell death

scientific article published on 25 November 2019

Substrate polyspecificity and conformational relevance in ABC transporters: new insights from structural studies ⬇️

scientific article published on 04 December 2018

Subunit positioning and stator filament stiffness in regulation and power transmission in the V1 motor of the Manduca sexta V-ATPase ⬇️

artículo científico publicado en 2013

T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest

artículo científico publicado en 2010

TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p ⬇️

artículo científico publicado en 2017

The Acanthamoeba shikimate pathway has a unique molecular arrangement and is essential for aromatic amino acid biosynthesis

artículo científico publicado en 2014

The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery ⬇️

artículo científico publicado en 2017

The Vacuolar ATPase - A Nano-scale Motor That Drives Cell Biology.

artículo científico publicado en 2018

The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer

scientific article published on 21 March 2020

The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target

artículo científico publicado en 2014

The changing landscape of membrane protein structural biology through developments in electron microscopy ⬇️

artículo científico publicado en 2016

The conservation of phosphate-binding residues among PHT1 transporters suggests that distinct transport affinities are unlikely to result from differences in the phosphate-binding site ⬇️

artículo científico publicado en 2016

The essential GTPase YphC displays a major domain rearrangement associated with nucleotide binding

artículo científico publicado en 2006

The expanding toolkit for structural biology: synchrotrons, X-ray lasers and cryoEM

scientific article published on 01 March 2019

The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design. ⬇️

artículo científico publicado en 2017

The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. ⬇️

artículo científico publicado en 2014

The varied functions of aluminium-activated malate transporters-much more than aluminium resistance ⬇️

artículo científico publicado en 2016

Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.

artículo científico publicado en 2001

Type I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structure

artículo científico publicado en 2007

Understanding the apparent stator-rotor connections in the rotary ATPase family using coarse-grained computer modeling ⬇️

artículo científico publicado en 2014

Using a SMALP platform to determine a sub-nm single particle cryo-EM membrane protein structure. ⬇️

artículo científico publicado en 2017

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery. ⬇️

artículo científico publicado en 2018

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