Lista de obras - Juan M Falcón-Pérez - Dominio Público Uruguay

A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients

artículo científico publicado en 2017

A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

scientific article published on 23 December 2016

A Pilot Study on the Potential of RNA-Associated to Urinary Vesicles as a Suitable Non-Invasive Source for Diagnostic Purposes in Bladder Cancer.

scientific article published on 22 January 2014

A fast method for the quantitation of key metabolites of the methionine pathway in liver tissue by high-resolution mass spectrometry and hydrophilic interaction ultra-performance liquid chromatography

artículo científico publicado en 2013

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

artículo científico publicado en 2017

Abundance of Cytochromes in Hepatic Extracellular Vesicles Is Altered by Drugs Related With Drug-Induced Liver Injury

artículo científico publicado en 2018

Assessing the role of surface glycans of extracellular vesicles on cellular uptake

scientific article published on 15 August 2019

BLOC-1 deficiency causes alterations in amino acid profile and in phospholipid and adenosine metabolism in the postnatal mouse hippocampus.

artículo científico publicado en 2017

BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes

scientific journal article

BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules

artículo científico publicado en 2002

Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4

artículo científico publicado en 2003

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

artículo científico publicado en 2021

Cellular uptake of gold nanoparticles bearing HIV gp120 oligomannosides

artículo científico publicado en 2012

Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes

artículo científico publicado en 2008

Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6

artículo científico publicado en 2004

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

artículo científico publicado en 2018

Comparative miRNA Analysis of Urine Extracellular Vesicles Isolated through Five Different Methods

artículo científico publicado en 2016

Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

artículo científico publicado en 2018

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

artículo científico publicado en 2005

Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains

artículo científico publicado en 2001

EV-Associated miRNAs from Peritoneal Lavage are a Source of Biomarkers in Endometrial Cancer

scientific article published on 18 June 2019

EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer

artículo científico publicado en 2019

EVpedia: a community web portal for extracellular vesicles research

artículo científico publicado en 2014

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion

artículo científico publicado en 2014

Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin-Stimulated Glucose Uptake

artículo científico publicado en 2018

Fast characterisation of cell-derived extracellular vesicles by nanoparticles tracking analysis, cryo-electron microscopy, and Raman tweezers microspectroscopy

artículo científico publicado en 2012

First Symposium of "Grupo Español de Investigación en Vesículas Extracelulares (GEIVEX)", Segovia, 8-9 November 2012.

artículo científico publicado en 2013

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

artículo científico publicado en 2017

Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis

scientific article published on 01 August 1999

Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives.

artículo científico publicado en 2018

Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism.

artículo científico publicado en 2017

Hereditary tyrosinemia type I-associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate

artículo científico publicado en 2019

Human mammospheres secrete hormone-regulated active extracellular vesicles

artículo científico publicado en 2014

Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles

scientific article published on 17 March 2017

Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

artículo científico publicado en 2011

Isolation and characterization of exosomes derived from fertile sheep hydatid cysts.

artículo científico publicado en 2017

Isolation of urinary exosomes from animal models to unravel noninvasive disease biomarkers.

artículo científico publicado en 2012

Liver extracellular vesicles in health and disease

artículo científico publicado en 2012

Low-dose statin treatment increases prostate cancer aggressiveness.

artículo científico publicado en 2017

Meeting report of the European mouse complex genetics network SYSGENET.

artículo científico publicado en 2013

Metabolic alterations in urine extracellular vesicles are associated to prostate cancer pathogenesis and progression.

artículo científico publicado en 2018

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

artículo científico publicado en 2017

Metabolomics Applied to the Study of Extracellular Vesicles

scientific article published on 12 November 2019

Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee

scientific article published on 25 August 2020

Microarray-Based Identification of Lectins for the Purification of Human Urinary Extracellular Vesicles Directly from Urine Samples

artículo científico publicado en 2014

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Non-invasive detection of drug toxicity in rats by solid-phase extraction and MALDI-TOF analysis of urine samples.

artículo científico publicado en 2013

Overview of extracellular microvesicles in drug metabolism.

scientific article published on May 2010

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

artículo científico publicado en 2012

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.

artículo científico publicado en 2011

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity

artículo científico publicado en 2014

Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma.

artículo científico publicado en 2018

Role of Aramchol in steatohepatitis and fibrosis in mice

artículo científico publicado en 2017

SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity

artículo científico publicado en 2009

Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity

artículo científico publicado en 2011

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma.

artículo científico publicado en 2017

Sorting signal targeting mRNA into hepatic extracellular vesicles

artículo científico publicado en 2014

Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase: molecular basis of congenital erythropoietic porphyria.

scientific article published on January 2011

Sub‐proteome approach to the knowledge of liver ⬇️

artículo científico publicado el 3 de febrero de 2010

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017.

artículo científico publicado en 2018

Synthesis, dihydrofolate reductase inhibition, anti-proliferative testing, and saturation transfer difference ¹H-NMR study of some new 2-substituted-4,6-diaminopyrimidine derivatives

artículo científico publicado en 2012

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

artículo científico publicado en 2018

Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality

scientific journal article

Tau Overexpression Results in Its Secretion via Membrane Vesicles

scientific article published on 21 January 2012

The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5).

artículo científico publicado en 2006

The First Dose of Fingolimod Affects Circulating Extracellular Vesicles in Multiple Sclerosis Patients

artículo científico publicado en 2018

The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis

artículo científico publicado en 2002

Transcriptome of extracellular vesicles released by hepatocytes.

artículo científico publicado en 2013

Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria

artículo científico publicado en 2014

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility.

artículo científico publicado en 2017

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

artículo científico publicado en 2012

Virtual expert mass spectrometrist: iTRAQ tool for database-dependent search, quantitation and result storage.

artículo científico publicado en 2010

Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.

artículo científico publicado en 2004

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes

artículo científico publicado en 2007

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.

artículo científico publicado en 2017

miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments

artículo científico publicado en 2009

Lista de obras de Juan M Falcón-Pérez

A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients

A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

A Pilot Study on the Potential of RNA-Associated to Urinary Vesicles as a Suitable Non-Invasive Source for Diagnostic Purposes in Bladder Cancer.

A fast method for the quantitation of key metabolites of the methionine pathway in liver tissue by high-resolution mass spectrometry and hydrophilic interaction ultra-performance liquid chromatography

A novel community driven software for functional enrichment analysis of extracellular vesicles data.

Abundance of Cytochromes in Hepatic Extracellular Vesicles Is Altered by Drugs Related With Drug-Induced Liver Injury

Assessing the role of surface glycans of extracellular vesicles on cellular uptake

BLOC-1 deficiency causes alterations in amino acid profile and in phospholipid and adenosine metabolism in the postnatal mouse hippocampus.

BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes

BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules

Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4

Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart

Cellular uptake of gold nanoparticles bearing HIV gp120 oligomannosides

Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes

Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

Comparative miRNA Analysis of Urine Extracellular Vesicles Isolated through Five Different Methods

Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

Domain interactions in the yeast ATP binding cassette transporter Ycf1p: intragenic suppressor analysis of mutations in the nucleotide binding domains

EV-Associated miRNAs from Peritoneal Lavage are a Source of Biomarkers in Endometrial Cancer

EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer

EVpedia: a community web portal for extracellular vesicles research

Exosomes as Hedgehog carriers in cytoneme-mediated transport and secretion

Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin-Stimulated Glucose Uptake

Fast characterisation of cell-derived extracellular vesicles by nanoparticles tracking analysis, cryo-electron microscopy, and Raman tweezers microspectroscopy

First Symposium of "Grupo Español de Investigación en Vesículas Extracelulares (GEIVEX)", Segovia, 8-9 November 2012.

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis

Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives.

Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism.

Hereditary tyrosinemia type I-associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate

Human mammospheres secrete hormone-regulated active extracellular vesicles

Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles

Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

Isolation and characterization of exosomes derived from fertile sheep hydatid cysts.

Isolation of urinary exosomes from animal models to unravel noninvasive disease biomarkers.

Liver extracellular vesicles in health and disease

Low-dose statin treatment increases prostate cancer aggressiveness.

Meeting report of the European mouse complex genetics network SYSGENET.

Metabolic alterations in urine extracellular vesicles are associated to prostate cancer pathogenesis and progression.

Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis.

Metabolomics Applied to the Study of Extracellular Vesicles

Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee

Microarray-Based Identification of Lectins for the Purification of Human Urinary Extracellular Vesicles Directly from Urine Samples

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Non-invasive detection of drug toxicity in rats by solid-phase extraction and MALDI-TOF analysis of urine samples.

Overview of extracellular microvesicles in drug metabolism.

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.

Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity

Rab35-dependent extracellular nanovesicles are required for induction of tumour supporting stroma.

Role of Aramchol in steatohepatitis and fibrosis in mice

SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity

Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity

Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma.

Sorting signal targeting mRNA into hepatic extracellular vesicles

Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase: molecular basis of congenital erythropoietic porphyria.

Sub‐proteome approach to the knowledge of liver ⬇️

Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017.

Synthesis, dihydrofolate reductase inhibition, anti-proliferative testing, and saturation transfer difference ¹H-NMR study of some new 2-substituted-4,6-diaminopyrimidine derivatives

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality

Tau Overexpression Results in Its Secretion via Membrane Vesicles

The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5).

The First Dose of Fingolimod Affects Circulating Extracellular Vesicles in Multiple Sclerosis Patients

The pallidin (Pldn) gene and the role of SNARE proteins in melanosome biogenesis

Transcriptome of extracellular vesicles released by hepatocytes.

Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility.

Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

Virtual expert mass spectrometrist: iTRAQ tool for database-dependent search, quantitation and result storage.

Ycf1-dependent cadmium detoxification by yeast requires phosphorylation of residues Ser908 and Thr911.

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.

miRanalyzer: a microRNA detection and analysis tool for next-generation sequencing experiments