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Lista de obras de Alfredo Fusco

2-Iodohexadecanal inhibits thyroid cell growth in part through the induction of let-7f microRNA.

artículo científico publicado en 2015

A 12q13 translocation involving the HMGI-C gene in richter transformation of a chronic lymphocytic leukemia

scientific article published on 01 May 2000

A 3.4-kbp transcript of ZNF331 is solely expressed in follicular thyroid adenomas.

artículo científico publicado en 2003

A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors

artículo científico publicado en 1999

A TSH-CREB1-microRNA Loop Is Required for Thyroid Cell Growth ⬇️

artículo científico publicado el 4 de agosto de 2011

A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

artículo científico publicado en 2007

A differential proteomic approach to identify proteins associated with thyroid cell transformation.

artículo científico publicado en 2005

A miRNA signature associated with human metastatic medullary thyroid carcinoma.

artículo científico

A new mechanism of BRAF activation in human thyroid papillary carcinomas

artículo científico publicado en 2005

A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

artículo científico publicado en 1987

A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor

artículo científico publicado en 2000

A potential pathogenetic mechanism for multiple endocrine neoplasia type 2 syndromes involves ret-induced impairment of terminal differentiation of neuroepithelial cells.

artículo científico publicado en 1996

A truncated HMGA1 gene induces proliferation of the 3T3-L1 pre-adipocytic cells: a model of human lipomas

artículo científico publicado en 2003

Aberrant expression, function and localization of connexins in human esophageal carcinoma cell lines with different degrees of tumorigenicity

artículo científico publicado en 1994

Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer.

artículo científico publicado en 2006

Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

artículo científico publicado en 2000

Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1.

artículo científico publicado en 2012

An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue

artículo científico publicado en 2003

An intracellular multi-effector complex mediates somatostatin receptor 1 activation of phospho-tyrosine phosphatase eta

scientific journal article

Analysis of the HMGI nuclear proteins in mouse neoplastic cells induced by different procedures

artículo científico publicado en 1989

Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation

artículo científico publicado en 2005

Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells

artículo científico publicado en 2004

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

artículo científico publicado en 2003

Breakpoints of 19q13 translocations of benign thyroid tumors map within a 400 kilobase region

artículo científico publicado en 1997

CBX7 is a tumor suppressor in mice and humans

artículo científico publicado en 2012

CBX7 modulates the expression of genes critical for cancer progression

artículo científico publicado en 2014

CCDC6 represses CREB1 activity by recruiting histone deacetylase 1 and protein phosphatase 1.

artículo científico publicado en 2010

CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas

artículo científico publicado en 2011

Characterization of HMGA1P6 transgenic mouse embryonic fibroblasts

scientific article published on 13 August 2020

Childhood hepatocellular tumors in FAP.

artículo científico publicado en 1997

Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells.

artículo científico publicado en 2010

Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein

scientific journal article

Cloning of the rat tissue inhibitor of metalloproteinases type 2 (TIMP-2) gene: analysis of its expression in normal and transformed thyroid cells.

artículo científico publicado en 1994

Comprehensive conventional and molecular cytogenetic characterization of B-CPAP, a human papillary thyroid carcinoma-derived cell line.

artículo científico publicado en 2004

Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels

artículo científico publicado en 2003

Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors

artículo científico publicado en 2013

Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland

scientific journal article

Crystallization and preliminary X-ray diffraction analysis of rat protein tyrosine phosphatase eta

artículo científico publicado en 2006

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

artículo científico publicado en 2002

DNA damage, homology-directed repair, and DNA methylation

artículo científico publicado en 2007

DNA methylation state of the galectin-3 gene represents a potential new marker of thyroid malignancy.

artículo científico publicado en 2013

Deregulation of microRNA expression in follicular-cell-derived human thyroid carcinomas

scientific article published on 29 January 2010

Deregulation of microRNA expression in thyroid neoplasias

artículo científico publicado en 2013

Detection of high-mobility group proteins A1 and A2 represents a valid diagnostic marker in post-pubertal testicular germ cell tumours

article

Diagnostic significance of high mobility group I(Y) protein expression in intraductal papillary mucinous tumors of the pancreas

scientific article published on 01 August 2002

Different mutations of the RET gene cause different human tumoral diseases.

artículo científico publicado en 1999

Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation

artículo científico publicado en 2013

Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors

artículo científico publicado en 2004

Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

artículo científico publicado en 2001

Down-regulation of oestrogen receptor-β associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas.

artículo científico publicado en 2011

Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2.

artículo científico publicado en 2012

Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesis

artículo científico publicado en 2011

Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors

artículo científico publicado en 2015

Dysfunction of the RET receptor in human cancer

artículo científico publicado en 2004

E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression

artículo científico publicado en 2006

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

artículo científico publicado en 2003

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene

artículo científico publicado en 2013

Enhancer of zeste homolog 2 overexpression has a role in the development of anaplastic thyroid carcinomas

artículo científico publicado en 2011

Establishment of a non-tumorigenic papillary thyroid cell line (FB-2) carrying the RET/PTC1 rearrangement

artículo científico publicado en 2002

Expression and alternative splicing of c-ret RNA in papillary thyroid carcinomas

artículo científico publicado en 2001

Expression of CD133 in differentiated thyroid cancer of young patients

artículo científico publicado en 2015

Expression of galectin-1 in normal human thyroid gland and in differentiated and poorly differentiated thyroid tumors

artículo científico publicado en 1995

Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis

scientific article published on 01 January 1997

Expression of the soluble lectin L-14 gene is induced by TSH in thyroid cells and suppressed by retinoic acid in transformed neural cells.

artículo científico publicado en 1994

Expression, purification, and characterization of rat protein tyrosine phosphatase eta catalytic domain.

artículo científico publicado en 2005

FEZ1/LZTS1 protein expression in ovarian cancer.

artículo científico publicado en 2010

FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders

artículo científico publicado en 2007

Familial cancer associated with a polymorphism in ARLTS1

artículo científico publicado en 2005

Fenofibrate increases the expression of high mobility group AT-hook 2 (HMGA2) gene and induces adipocyte differentiation of orbital fibroblasts from Graves' ophthalmopathy

artículo científico publicado en 2004

Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription

scientific journal article

Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas

artículo científico publicado en 2004

Functional variants of the HMGA1 gene and type 2 diabetes mellitus

artículo científico publicado en 2011

Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis.

artículo científico publicado en 2006

Genetic alterations in thyroid carcinoma associated with familial adenomatous polyposis: clinical implications and suggestions for early detection

scientific article published on 01 December 1998

Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.

artículo científico publicado en 1998

Group I p21-activated kinases regulate thyroid cancer cell migration and are overexpressed and activated in thyroid cancer invasion ⬇️

artículo científico publicado el 29 de octubre de 2010

HAND1 gene expression is negatively regulated by the High Mobility Group A1 proteins and is drastically reduced in human thyroid carcinomas

article

HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody

artículo científico publicado en 2012

HMGA and cancer

artículo científico publicado en 2010

HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents

artículo científico publicado en 2011

HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas

scientific journal article

HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma

artículo científico publicado en 2012

HMGA1 negatively regulates NUMB expression at transcriptional and post transcriptional level in glioblastoma stem cells

scientific article published on 22 May 2019

HMGA1 overexpression is associated with a particular subset of human breast carcinomas

artículo científico publicado en 2015

HMGA1 protein expression in familial breast carcinoma patients

artículo científico publicado en 2009

HMGA1 protein expression sensitizes cells to cisplatin-induced cell death

artículo científico publicado en 2005

HMGA1 protein is a novel target of the ATM kinase

artículo científico publicado en 2008

HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas

artículo científico publicado en 2003

HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression

artículo científico publicado en 2004

HMGA1-pseudogene overexpression contributes to cancer progression

artículo científico publicado en 2014

HMGA2 cooperates with either p27(kip1) deficiency or Cdk4(R24C) mutation in pituitary tumorigenesis.

artículo científico publicado en 2017

HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity

artículo científico publicado en 2006

HMGA2 mRNA expression correlates with the malignant phenotype in human thyroid neoplasias.

artículo científico publicado en 2008

HMGA2: A pituitary tumour subtype-specific oncogene?

artículo científico publicado en 2010

HMGIY is the target of 6p21.3 rearrangements in various benign mesenchymal tumors

artículo científico publicado en 1998

Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.

artículo científico publicado en 2006

High mobility group A-interacting proteins in cancer: focus on chromobox protein homolog 7, homeodomain interacting protein kinase 2 and PATZ

article

High mobility group A1 is expressed in metastatic adenocarcinoma to the liver and intrahepatic cholangiocarcinoma, but not in hepatocellular carcinoma: its potential use in the diagnosis of liver neoplasms.

artículo científico publicado en 2003

High-mobility group A1 protein: a new coregulator of peroxisome proliferator-activated receptor-γ-mediated transrepression in the vasculature.

artículo científico publicado en 2011

High-mobility group A1 proteins are overexpressed in human leukaemias

artículo científico publicado en 2003

High-mobility group A1 proteins regulate p53-mediated transcription of Bcl-2 gene

artículo científico publicado en 2010

High-mobility group A2 gene expression is frequently induced in non-functioning pituitary adenomas (NFPAs), even in the absence of chromosome 12 polysomy

artículo científico publicado en 2005

High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2).

artículo científico publicado en 2005

Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation.

artículo científico publicado en 2009

Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis

artículo científico publicado en 2007

IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.

artículo científico publicado en 2005

Identification and Characterization of a Novel RING-Finger Gene (RNF4) Mapping at 4p16.3 ⬇️

artículo científico publicado el 15 de enero de 1998

Identification of a New Pathway for Tumor Progression: MicroRNA-181b Up-Regulation and CBX7 Down-Regulation by HMGA1 Protein

artículo científico publicado en 2010

Identification of new high mobility group A1 associated proteins.

artículo científico publicado en 2007

Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity

artículo científico publicado en 2012

Identification of the genes up- and down-regulated by the high mobility group A1 (HMGA1) proteins: tissue specificity of the HMGA1-dependent gene regulation

artículo científico publicado en 2004

Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice

artículo científico publicado en 2009

Increased BDNF promoter methylation in the Wernicke area of suicide subjects.

artículo científico publicado en 2010

Inhibitory effects of 2-iodohexadecanal on FRTL-5 thyroid cells proliferation

artículo científico publicado en 2015

Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth

artículo científico publicado en 2002

Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: comparison with FRTL-5 cells

artículo científico publicado en 1999

Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation.

artículo científico publicado en 2014

Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage.

artículo científico publicado en 2007

Iodide symporter gene expression in normal and transformed rat thyroid cells.

artículo científico publicado en 1999

Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity

artículo científico publicado en 2012

Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice

artículo científico publicado en 2005

Let-7a down-regulation plays a role in thyroid neoplasias of follicular histotype affecting cell adhesion and migration through its ability to target the FXYD5 (Dysadherin) gene

artículo científico publicado en 2012

Ligand stimulation of a Ret chimeric receptor carrying the activating mutation responsible for the multiple endocrine neoplasia type 2B.

artículo científico publicado en 1996

Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage.

artículo científico publicado en 2012

Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer.

artículo científico publicado en 2010

Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.

artículo científico publicado en 2005

Lost in translation: bridging the gap between cancer research and effective therapies.

artículo científico publicado en 2011

Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells

artículo científico publicado en 2007

MiR-1 is a tumor suppressor in thyroid carcinogenesis targeting CCND2, CXCR4, and SDF-1alpha

artículo científico publicado en 2011

MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1.

artículo científico publicado en 2015

MicroRNA deregulation in human thyroid papillary carcinomas.

artículo científico publicado en 2006

MicroRNAs: a great challenge for the diagnosis and therapy of endocrine cancers.

artículo científico publicado en 2010

Mir-23b and miR-130b expression is downregulated in pituitary adenomas

artículo científico publicado en 2014

Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages

artículo científico publicado en 2013

Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma

artículo científico publicado en 2005

Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

artículo científico publicado en 1999

Molecular biology of the MEN2 gene.

artículo científico publicado en 1998

Molecular mechanisms of the increased glucose transport in transformed FRTL-5 rat thyroid cells

artículo científico publicado en 1993

Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations.

artículo científico publicado en 2005

Multipotential hemopoietic cell lines isolated from stem cell cultures infected with Friend virus complex (MuLV + F-SFFV) show presence of MuLV but not F-SFFV.

artículo científico publicado en 1986

Mutation of the PIK3CA gene in anaplastic thyroid cancer.

artículo científico publicado en 2005

Mycalol: a natural lipid with promising cytotoxic properties against human anaplastic thyroid carcinoma cells

artículo científico publicado en 2013

NCOA4 transcriptional coactivator inhibits activation of DNA replication origins

artículo científico publicado en 2014

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

artículo científico publicado en 2003

Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product

artículo científico publicado en 1997

Norepinephrine and thyrotropin stimulation of [Ca++]i in PC C13 a rat thyroid epithelial cell line: effect of transformation by E1A gene adenovirus and polyomavirus middle-T antigen gene

artículo científico publicado en 1993

Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer

artículo científico publicado en 2004

ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells

article by Giuseppe Portella et al published October 2003 in The Journal of Clinical Endocrinology and Metabolism

ONYX-015, an E1B gene-defective adenovirus, induces cell death in human anaplastic thyroid carcinoma cell lines

article

Oncogene transformation of PC Cl3 clonal thyroid cell line induces an autonomous pattern of proliferation that correlates with a loss of basal and stimulated phosphotyrosine phosphatase activity

artículo científico publicado en 1997

Oncogenic alterations in papillary thyroid cancers of young patients

artículo científico publicado en 2011

Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential

artículo científico publicado en 1997

Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway

artículo científico publicado en 2001

Overexpression of the S-phase kinase-associated protein 2 in thyroid cancer

artículo científico publicado en 2007

PATZ attenuates the RNF4-mediated enhancement of androgen receptor-dependent transcription

artículo científico publicado en 2001

PATZ1 gene has a critical role in the spermatogenesis and testicular tumours

scientific journal article

PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context

artículo científico publicado en 2013

PIT1 upregulation by HMGA proteins has a role in pituitary tumorigenesis

artículo científico publicado en 2012

POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

artículo científico publicado en 2012

Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes

scientific journal article

Pivotal role of the RB family proteins in in vitro thyroid cell transformation

artículo científico publicado en 2000

Point mutation in GRIM-19: a new genetic lesion in Hurthle cell thyroid carcinomas

artículo científico publicado en 2005

Point mutation of the RET proto-oncogene in the TT human medullary thyroid carcinoma cell line

artículo científico publicado en 1995

Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the bcl-2 gene

artículo científico publicado en 1999

Protein kinase C activities are increased in rat thyroid epithelial cells expressing v-ras genes.

artículo científico publicado en 1988

Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328.

artículo científico publicado en 2012

Protein tyrosine phosphatase-eta expression is upregulated by the PKA-dependent and is downregulated by the PKC-dependent pathways in thyroid cells.

artículo científico publicado en 1998

RET activation and clinicopathologic features in poorly differentiated thyroid tumors

artículo científico publicado en 2002

RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions.

artículo científico publicado en 2002

RET/PTC activation in hyalinizing trabecular tumors of the thyroid

scientific article published on 01 December 2000

RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture

artículo científico publicado en 2006

RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.

artículo científico publicado en 2001

RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.

artículo científico publicado en 2006

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase.

artículo científico

RETRACTED: Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation

artículo científico publicado en 2001

RETRACTED: Targeted disruption of the murine homeodomain-interacting protein kinase-2 causes growth deficiency in vivo and cell cycle arrest in vitro

artículo científico publicado en 2009

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes

artículo científico publicado en 2003

Rat protein tyrosine phosphatase eta physically interacts with the PDZ domains of syntenin

artículo científico publicado en 2001

Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).

artículo científico publicado en 2000

Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

artículo científico publicado en 2005

Regulation of BRCA1 transcription by specific single-stranded DNA binding factors

artículo científico publicado en 2003

Regulation of microRNA expression by HMGA1 proteins

artículo científico publicado en 2009

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells.

artículo científico publicado en 2004

Regulation of thymosin beta10 expression by TSH and other mitogenic signals in the thyroid gland and in cultured thyrocytes

artículo científico publicado en 1999

Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment.

artículo científico publicado en 2015

Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo

artículo científico publicado en 2004

Role of Dicer1 in thyroid cell proliferation and differentiation.

artículo científico publicado en 2017

Role of PTPRJ genotype in papillary thyroid carcinoma risk

artículo científico publicado en 2010

Role of the high mobility group A proteins in the regulation of pituitary cell cycle

artículo científico publicado en 2010

Roles of HMGA proteins in cancer

artículo científico publicado en 2007

SOM230, A New Somatostatin Analogue, Is Highly Effective in the Therapy of Growth Hormone/Prolactin-Secreting Pituitary Adenomas

scientific article published on 01 May 2007

Sp1 and CTF/NF-1 transcription factors are involved in the basal expression of the Hmgi-c proximal promoter

artículo científico publicado en 1999

Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.

artículo científico publicado en 2007

Status and expression of thep16INK4 gene in human thyroid tumors and thyroid-tumor cell lines

article

Structural model of the hUbA1-UbcH10 quaternary complex: in silico and experimental analysis of the protein-protein interactions between E1, E2 and ubiquitin

artículo científico publicado en 2014

TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters.

artículo científico publicado en 2013

TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma.

artículo científico publicado en 2010

TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype

artículo científico publicado en 2011

The "next-generation" knowledge of papillary thyroid carcinoma

artículo científico

The HMGA1-IGF-I/IGFBP system: a novel pathway for modulating glucose uptake

artículo científico publicado en 2012

The HMGA1-pseudogene7 shows oncogenic activity in vivo

artículo científico publicado en 2020

The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression

artículo científico publicado en 2013

The Mia/Cd-rap gene expression is downregulated by the high-mobility group A proteins in mouse pituitary adenomas.

artículo científico publicado en 2007

The RET/PTC oncogene is frequently activated in oncocytic thyroid tumors (Hurthle cell adenomas and carcinomas), but not in oncocytic hyperplastic lesions

artículo científico publicado en 2002

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

artículo científico publicado en 2005

The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane

artículo científico publicado en 2001

The activation of the phosphotyrosine phosphatase eta (r-PTP eta) is responsible for the somatostatin inhibition of PC Cl3 thyroid cell proliferation

artículo científico publicado en 2001

The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

artículo científico publicado en 2009

The block of thyroglobulin synthesis, which occurs upon transformation of rat thyroid epithelial cells, is at the transcriptional level and it is associated with methylation of the 5' flanking region of the gene

scientific article published on 01 August 1989

The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis

artículo científico publicado en 2009

The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias.

artículo científico publicado en 2014

The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes and cell localization

artículo científico publicado en 2009

The expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferation

artículo científico publicado en 2004

The high-mobility group A1-estrogen receptor β nuclear interaction is impaired in human testicular seminomas.

artículo científico publicado en 2012

The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues

artículo científico publicado en 2002

The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin

article

The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.

artículo científico publicado en 2001

The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists.

artículo científico publicado en 2008

The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.

artículo científico publicado en 2010

The phosphotyrosine phosphatase eta mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK1/2.

artículo científico publicado en 2004

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins

artículo científico publicado en 2006

The ret/ptc1 oncogene is activated in familial adenomatous polyposis-associated thyroid papillary carcinomas

artículo científico publicado en 1998

The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis

artículo científico publicado en 2004

Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models

artículo científico publicado en 2004

Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase

artículo científico publicado en 1997

Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas

scientific article published on 19 June 2006

Thyrotropin receptor gene expression in oncogene-transfected rat thyroid cells: correlation between transformation, loss of thyrotropin-dependent growth, and loss of thyrotropin receptor gene expression

artículo científico publicado en 1990

Thyrotropin regulates thyroid cell proliferation by up-regulating miR-23b and miR-29b that target SMAD3.

artículo científico publicado en 2012

Transcriptional profile of Ki-Ras-induced transformation of thyroid cells

artículo científico publicado en 2007

Transformation of mononuclear phagocytes in vivo and malignant histiocytosis caused by a novel murine spleen focus-forming virus

artículo científico publicado en 1985

Transformation of rat thyroid epithelial cells by Kirsten murine sarcoma virus

artículo científico publicado en 1981

Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

artículo científico publicado en 2005

Translational regulation of a novel testis-specific RNF4 transcript

artículo científico publicado en 2003

Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis

artículo científico publicado en 2013

UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients

artículo científico publicado en 2015

UbcH10 expression in human lymphomas.

artículo científico publicado en 2009

UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas

artículo científico publicado en 2006

UbcH10 expression on thyroid fine-needle aspirates.

artículo científico publicado en 2010

UbcH10 is overexpressed in malignant breast carcinomas

artículo científico publicado en 2007

UbcH10 overexpression in human lung carcinomas and its correlation with EGFR and p53 mutational status.

artículo científico publicado en 2012

UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas

artículo científico publicado en 2005

Up-regulation of miR-146b and Down-regulation of miR-200b Contribute to the Cytotoxic Effect of Histone Deacetylase Inhibitors onras-Transformed Thyroid Cells

artículo científico publicado en 2013

Upregulation of miR-21 by Ras in vivo and its role in tumor growth.

artículo científico publicado en 2010

Wnt4 inhibits cell motility induced by oncogenic Ras

artículo científico publicado en 2013

miR-142-3p down-regulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1.

artículo científico publicado en 2015

miR-191 down-regulation plays a role in thyroid follicular tumors through CDK6 targeting.

artículo científico publicado en 2011

siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma

artículo científico publicado en 2007

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