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Lista de obras de Junken Aoki

1-Fluoro-2,4-dinitrobenzene and its derivatives act as secretagogues on rodent mast cells

artículo científico publicado en 2016

A 3D view of autotaxin

artículo científico publicado en 2012

A New Enzyme Immunoassay for the Quantitative Determination of Classical Autotaxins (ATXα, ATXβ, and ATXγ) and Novel Autotaxins (ATXδ and ATXε).

artículo científico publicado en 2015

A missense mutation within the helix initiation motif of the keratin K71 gene underlies autosomal dominant woolly hair/hypotrichosis

artículo científico publicado en 2012

A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A1 in human serum samples

scientific article published on 11 April 2010

A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1α in autosomal recessive wooly hair/hypotrichosis

artículo científico publicado en 2013

A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid

artículo científico publicado en 2002

A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125.

artículo científico publicado en 2002

A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7.

artículo científico publicado en 2002

ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells

artículo científico publicado en 2006

ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation

artículo científico publicado en 2016

Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer

artículo científico publicado en 2004

Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells

artículo científico publicado en 2006

Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice

artículo científico publicado en 2009

Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors

artículo científico publicado en 2004

Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model

scientific article published on 12 November 2019

An alternative splicing form of phosphatidylserine-specific phospholipase A1 that exhibits lysophosphatidylserine-specific lysophospholipase activity in humans

artículo científico publicado en 1999

Analysis of lissencephaly-causingLIS1mutations

article

Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome

artículo científico publicado en 2008

Analysis of unique mutations in the LPAR6 gene identified in a Japanese family with autosomal recessive woolly hair/hypotrichosis: Establishment of a useful assay system for LPA6.

artículo científico publicado en 2015

Anti-idiotypic monoclonal antibody recognizes a consensus recognition site for phosphatidylserine in phosphatidylserine-specific monoclonal antibody and protein kinase C

artículo científico publicado en 1994

Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma

artículo científico publicado en 2007

Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid-Mediated Autocrine Mechanism.

artículo científico publicado en 2016

Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine

artículo científico publicado en 2010

Autotaxin as a novel serum marker of liver fibrosis.

artículo científico publicado en 2011

Autotaxin controls caudal diencephalon-mesencephalon development in the chick.

artículo científico publicado en 2010

Autotaxin enzyme immunoassay in human cerebrospinal fluid samples

artículo científico publicado en 2009

Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid

artículo científico publicado en 2006

Autotaxin overexpression causes embryonic lethality and vascular defects

artículo científico publicado en 2015

Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish

artículo científico publicado en 2011

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

artículo científico publicado en 2006

Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

artículo científico publicado en 2008

Autotaxin--an LPA producing enzyme with diverse functions

artículo científico publicado en 2010

Autotaxin-lysophosphatidic acid-LPA3 signaling at the embryo-epithelial boundary controls decidualization pathways

artículo científico publicado en 2017

Autotaxin: A Unique Ecto-Type Pyrophosphodiesterase with Diverse Functions

Beta-catenin asymmetry is regulated by PLA1 and retrograde traffic in C. elegans stem cell divisions

artículo científico publicado en 2008

Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family

artículo científico publicado en 2005

Biochemical characterization of various catalytic complexes of the brain platelet-activating factor acetylhydrolase

artículo científico publicado en 1999

Biological roles of lysophosphatidic acid signaling through its production by autotaxin

artículo científico publicado en 2010

Blood levels of serotonin are specifically correlated with plasma lysophosphatidylserine among the glycero-lysophospholipids.

artículo científico publicado en 2015

Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

artículo científico publicado en 2007

Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

artículo científico publicado en 1997

Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts

artículo científico publicado en 2010

Characterization of three different transgenic mouse lines that carry human poliovirus receptor gene--influence of the transgene expression on pathogenesis.

artículo científico publicado en 1994

Clinical Introduction of Lysophosphatidic Acid (LPA) and Autotaxin Assays

Cloning and expression of a cDNA encoding the beta-subunit (30-kDa subunit) of bovine brain platelet-activating factor acetylhydrolase

artículo científico publicado en 1995

Comprehensive analysis of sphingosine-1-phosphate receptor mutants during zebrafish embryogenesis

artículo científico publicado en 2015

Conformational Constraint of the Glycerol Moiety of Lysophosphatidylserine Affords Compounds with Receptor Subtype Selectivity

artículo científico publicado en 2016

Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis

artículo científico publicado en 2013

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein

artículo científico publicado en 2020

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

artículo científico publicado en 2012

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

artículo científico publicado en 2011

Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500

scientific article published on 21 June 2019

Crystal structures of human ET receptor provide mechanistic insight into receptor activation and partial activation

scientific article published in Nature Communications

Cyclic phosphatidic acid is produced by autotaxin in blood

artículo científico publicado en 2006

Datura stramonium agglutinin released histamine from rat peritoneal mast cells that was inhibited by pertussis toxin, haptenic sugar and N-acetylglucosamine-specific lectins: involvement of glycoproteins with N-acetylglucosamine residues

artículo científico

Decrease in circulating autotaxin by oral administration of prednisolone

artículo científico publicado en 2012

Detection of physiological activities of G protein-coupled receptor-acting pharmaceuticals in wastewater.

artículo científico publicado en 2015

Development of an activity-based probe for autotaxin

artículo científico publicado en 2010

Different origins of lysophospholipid mediators between coronary and peripheral arteries in acute coronary syndrome

artículo científico publicado en 2016

Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer

artículo científico publicado en 2006

Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE

artículo científico publicado en 2000

Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis

artículo científico publicado en 2017

Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development

artículo científico publicado en 2007

Diversified expression patterns ofautotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development

Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells

artículo científico publicado en 2004

ENPP2 Contributes to Adipose Tissue Expansion and Insulin Resistance in Diet-Induced Obesity

artículo científico publicado en 2014

Efficient delivery of circulating poliovirus to the central nervous system independently of poliovirus receptor.

artículo científico publicado en 1997

Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism

scientific article published on 21 January 2020

Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice1

artículo científico publicado en 2007

Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol

artículo científico publicado en 2009

Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity

artículo científico publicado en 2003

Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain

artículo científico publicado en 2010

Expression of NUDEL in manchette and its implication in spermatogenesis

artículo científico publicado en 2004

Expression of autotaxin and acylglycerol kinase in prostate cancer: association with cancer development and progression

artículo científico publicado en 2009

Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta.

artículo científico publicado en 2009

Expression of phosphatidylserine-specific phospholipase A(1) mRNA in human THP-1-derived macrophages

artículo científico publicado en 2010

Expression patterns of the lysophospholipid receptor genes during mouse early development

artículo científico publicado en 2008

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1.

artículo científico publicado en 2012

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp6.

artículo científico publicado en 2014

Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility

artículo científico publicado en 2016

Fluorescence probe for lysophospholipase C/NPP6 activity and a potent NPP6 inhibitor

artículo científico publicado en 2011

GPR34 as a lysophosphatidylserine receptor

artículo científico publicado en 2013

GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position

artículo científico publicado en 2012

Glucagon regulates intracellular distribution of adipose differentiation-related protein during triacylglycerol accumulation in the liver

artículo científico publicado en 2010

Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2

artículo científico publicado en 2005

Human adiponectin receptor AdipoR1 assumes closed and open structures

artículo científico publicado en 2020

Human placental trophoblast cells express alpha-tocopherol transfer protein

artículo científico publicado en 2003

Identification and biochemical characterization of a novel autotaxin isoform, ATXδ, with a four-amino acid deletion

artículo científico publicado en 2011

Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I

artículo científico publicado en 2000

Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis

scientific journal article

Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor

artículo científico publicado en 2003

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist

artículo científico publicado en 2002

Identification of lysophosphatidylthreonine with an aromatic fatty acid surrogate as a potent inducer of mast cell degranulation

artículo científico publicado en 2016

Identification of platelet-activating factor acetylhydrolase II in human skin

artículo científico publicado en 2002

Identifying specific conformations by using a carbohydrate scaffold: discovery of subtype-selective LPA-receptor agonists and an antagonist

artículo científico publicado en 2004

Immunohistochemical detection of autotaxin (ATX)/lysophospholipase D (lysoPLD) in submucosal invasive colorectal cancer

artículo científico publicado en 2011

Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.

artículo científico publicado en 2015

Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence.

artículo científico publicado en 2016

Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells

artículo científico publicado en 2005

Induction of protein kinase Czeta-related protein kinase by growth suppression in carcinogen-initiated epidermal cell-line WYF31 cells

artículo científico publicado en 2000

Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells

artículo científico publicado en 2015

Intracellular phospholipase A1gamma (iPLA1gamma) is a novel factor involved in coat protein complex I- and Rab6-independent retrograde transport between the endoplasmic reticulum and the Golgi complex

artículo científico publicado en 2009

Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions

artículo científico publicado en 2008

LIS1 missense mutations: variable phenotypes result from unpredictable alterations in biochemical and cellular properties

artículo científico publicado en 2003

LPA and its analogs-attractive tools for elucidation of LPA biology and drug development

artículo científico publicado en 2008

LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid

artículo científico publicado en 2010

LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling

artículo científico publicado en 2011

LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing

artículo científico publicado en 2005

LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells

artículo científico publicado en 2015

Localization of alpha-tocopherol transfer protein in rat brain

artículo científico publicado en 1998

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors

artículo científico publicado en 2002

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species

artículo científico publicado en 2000

Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.

artículo científico publicado en 2004

Lysophosphatidic acid and ovarian cancer: a paradigm for tumorogenesis and patient management.

artículo científico publicado en 2001

Lysophosphatidic acid as a lipid mediator with multiple biological actions

artículo científico publicado en 2014

Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.

artículo científico publicado en 2007

Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

artículo científico publicado en 2015

Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain

artículo científico publicado en 2009

Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis

artículo científico publicado en 2019

Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus

artículo científico publicado en 2006

Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid

artículo científico publicado en 2008

Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood.

artículo científico publicado en 2009

Lysophosphatidylserine analogues differentially activate three LysoPS receptors

artículo científico publicado en 2014

Lysophosphatidylserine suppresses IL-2 production in CD4 T cells through LPS3/GPR174.

artículo científico publicado en 2017

Lysophospholipid Mediators: Their Receptors and Synthetic Pathways

Maternal and Zygotic Sphingosine Kinase 2 Are Indispensable for Cardiac Development in Zebrafish

artículo científico publicado en 2015

Measurement of lysophospholipase D/autotaxin activity in human serum samples

artículo científico publicado en 2006

Measuring Activation of Lipid G Protein-Coupled Receptors Using the TGF-α Shedding Assay

Mechanisms of lysophosphatidic acid production

artículo científico publicado en 2004

Mitochondria-type GPAT is required for mitochondrial fusion

artículo científico publicado en 2013

Mitsugumin 56 (hedgehog acyltransferase-like) is a sarcoplasmic reticulum-resident protein essential for postnatal muscle maturation.

artículo científico publicado en 2015

Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid

artículo científico publicado en 1999

Molecular cloning of cDNAs encoding α1, α2, and β subunits of rat brain platelet-activating factor acetylhydrolase1The nucleotide sequence data reported in this paper have been submitted to the GenBank database under the accession number AF016047

article

Mouse homolog of poliovirus receptor-related gene 2 product, mPRR2, mediates homophilic cell aggregation

artículo científico publicado en 1997

NEURONAL DEVELOPMENT. Glycerophospholipid regulation of modality-specific sensory axon guidance in the spinal cord

artículo científico publicado en 2015

Necessity of lysophosphatidic acid receptor 1 for development of arthritis

artículo científico publicado en 2013

Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein

artículo científico publicado en 1999

Neuronal expression and neuritogenic action of group X secreted phospholipase A2

scientific journal article

Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia

artículo científico publicado en 2007

Non-cell autonomous and non-catalytic activities of ATX in the developing brain

artículo científico publicado en 2015

Novel lysophosphoplipid receptors: their structure and function

artículo científico publicado en 2014

Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma

artículo científico publicado en 2004

Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo.

artículo científico publicado en 2014

PAF analogues capable of inhibiting PAF acetylhydrolase activity suppress migration of isolated rat cerebellar granule cells

artículo científico publicado en 1997

PAF and PAF acetylhydrolase in the nervous system

artículo científico publicado en 1996

Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity

scientific article published on 15 February 2007

Phosphatidylserine-specific phospholipase A1 stimulates histamine release from rat peritoneal mast cells through production of 2-acyl-1-lysophosphatidylserine

artículo científico publicado en 2001

Phospholipase A1 Assays Using a Radiolabeled Substrate and Mass Spectrometry

scientific article published on 01 January 2007

Phospholipid localization implies microglial morphology and function via Cdc42 in vitro

artículo científico publicado en 2017

Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): Metabolically stabilized LPA receptor agonists

artículo científico publicado en 2013

Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists

artículo científico publicado en 2006

Placental autotaxin expression is diminished in women with pre-eclampsia.

artículo científico publicado en 2015

Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity

artículo científico publicado en 2007

Platelet-activating factor (PAF)-dependent transacetylase and its relationship with PAF acetylhydrolases

artículo científico publicado en 2000

Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor

scientific journal article

Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme

artículo científico publicado en 2001

Polycyclic aromatic hydrocarbons in samples of Ryugu formed in the interstellar medium

artículo científico publicado en 2023

Possible involvement of minor lysophospholipids in the increase in plasma lysophosphatidic acid in acute coronary syndrome

artículo científico publicado en 2014

Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin

artículo científico publicado en 2014

Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis

artículo científico publicado en 2010

Proliferation of mouse endometrial stromal cells in culture is highly sensitive to lysophosphatidic acid signaling

artículo científico publicado en 2017

Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma

artículo científico publicado en 2004

Protection against oxidative stress-induced cell death by intracellular platelet-activating factor-acetylhydrolase II.

artículo científico publicado en 1997

Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo

artículo científico publicado en 2007

Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain

scientific journal article

Regulation of intestinal IgA responses by dietary palmitic acid and its metabolism

artículo científico publicado en 2014

Regulation of peroxisomal lipid metabolism by catalytic activity of tumor suppressor H-rev107

scientific journal article

Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction.

artículo científico publicado en 2016

SEK1/MKK4-Mediated SAPK/JNK Signaling Participates in Embryonic Hepatoblast Proliferation via a Pathway Different from NF-κB-Induced Anti-Apoptosis

scientific article published on 01 October 2002

SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain

scientific journal article

Screening and X-ray crystal structure-based optimization of autotaxin (ENPP2) inhibitors, using a newly developed fluorescence probe

artículo científico publicado en 2013

Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MS

artículo científico publicado en 2014

Serum Autotaxin Levels Are Associated with Proteinuria and Kidney Lesions in Japanese Type 2 Diabetic Patients with Biopsy-proven Diabetic Nephropathy.

artículo científico publicado en 2016

Serum Autotaxin is not a Useful Biomarker for Ovarian Cancer

scientific article published on 15 June 2012

Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.

artículo científico publicado en 2008

Serum autotaxin measurements in pregnant women: application for the differentiation of normal pregnancy and pregnancy-induced hypertension.

artículo científico publicado en 2011

Serum lysophosphatidic acid is produced through diverse phospholipase pathways

artículo científico publicado en 2002

Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.

artículo científico publicado en 2007

Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry.

artículo científico publicado en 2012

Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain

artículo científico publicado en 2008

Specific increase in serum autotaxin activity in patients with pancreatic cancer

artículo científico publicado en 2011

Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration

artículo científico publicado en 2013

Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human

artículo científico publicado en 2016

Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation

scientific article published on 04 December 2019

Stepwise phosphorylation of leukotriene B4receptor 1 defines cellular responses to leukotriene B4

article

Structural basis for specific inhibition of Autotaxin by a DNA aptamer

artículo científico publicado en 2016

Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6.

artículo científico publicado en 2017

Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase

artículo científico publicado en 2016

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

artículo científico publicado en 2012

Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family

artículo científico publicado en 2007

Structure and function of phosphatidylserine-specific phospholipase A1

artículo científico publicado en 2002

Structure and selectivity engineering of the M1 muscarinic receptor toxin complex

artículo científico publicado en 2020

Structure of the dopamine D<sub>2</sub> receptor in complex with the antipsychotic drug spiperone

artículo científico publicado en 2020

Structure-activity relationships of fluorinated lysophosphatidic acid analogues

artículo científico publicado en 2005

Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine

scientific article published on 04 February 2019

Structure–Activity Relationships of Lysophosphatidylserine Analogs as Agonists of G-Protein-Coupled Receptors GPR34, P2Y10, and GPR174

artículo científico publicado en 2015

Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD)

artículo científico publicado en 2007

Sugar-Specific Inhibitory Effects of Wheat Germ Agglutinin and Phytohemagglutinin-E4 on Histamine Release Induced by Basic Secretagogues from Rat Peritoneal Mast Cells and Their Possible Action Sites

article by Tamiko Suzuki-Nishimura et al published 1991 in The Japanese Journal of Pharmacology

Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids

artículo científico publicado en 2011

Switching of platelet-activating factor acetylhydrolase catalytic subunits in developing rat brain

scientific journal article

Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling

article

Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.

artículo científico publicado en 2009

Synthesis and biological evaluation of optically active Ki16425.

artículo científico publicado en 2012

Synthesis and evaluation of lysophosphatidylserine analogues as inducers of mast cell degranulation. Potent activities of lysophosphatidylthreonine and its 2-deoxy derivative

artículo científico publicado en 2009

Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid

artículo científico publicado en 2003

Synthetic Biotinylated Peptide Compound, BP21, Specifically Recognizes Lysophosphatidylcholine Micelles

artículo científico publicado en 2012

Synthetic biotinylated peptide compounds derived from Asp-hemolysin: Novel potent inhibitors of platelet-activating factor

scientific article published on 20 April 2012

TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

artículo científico publicado en 2012

Targeted disruption of intracellular type I platelet activating factor-acetylhydrolase catalytic subunits causes severe impairment in spermatogenesis

scientific journal article

The experimental power of FR900359 to study Gq-regulated biological processes

artículo científico publicado en 2015

The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site

artículo científico publicado en 2003

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

scientific journal article

The β9 loop domain of PA-PLA1α has a crucial role in autosomal recessive woolly hair/hypotrichosis.

artículo científico publicado en 2012

Tissue tropism and species specificity of poliovirus infection

artículo científico publicado en 1994

Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function

artículo científico publicado en 2013

Transgenic expression of group V, but not group X, secreted phospholipase A2 in mice leads to neonatal lethality because of lung dysfunction

artículo científico publicado en 2006

Two pathways for lysophosphatidic acid production

artículo científico publicado en 2008

Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification

artículo científico publicado en 2007

Type II platelet-activating factor-acetylhydrolase is essential for epithelial morphogenesis in Caenorhabditis elegans

artículo científico publicado en 2004

Update on LIPID MAPS Classification, Nomenclature and Shorthand Notation for MS-derived Lipid Structures

scientific article published on 09 October 2020

Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation

artículo científico publicado en 2007

Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo

artículo científico publicado en 2003

X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog

artículo científico publicado en 2017

Zebrafish as a Model Animal for Studying Lysophosphatidic Acid Signaling

article

cDNA cloning and expression of human lactosylceramide synthase1The nucleotide sequence reported in this paper has been submitted to the GenBank Data Bank with accession number AF097159.1

article

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