Lista de obras - Frank N van Leeuwen - Dominio Público Uruguay

A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment

artículo científico publicado en 2015

A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics

artículo científico publicado en 2014

Activation of TRPM7 channels by phospholipase C-coupled receptor agonists

artículo científico publicado en 2006

B-lineage transcription factors and cooperating gene lesions required for leukemia development

artículo científico

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

artículo científico publicado en 2010

Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells

artículo científico publicado en 1994

Clinical outcomes after zotarolimus and everolimus drug eluting stent implantation in coronary artery bifurcation lesions: insights from the RESOLUTE All Comers Trial

article

Comparison of zotarolimus-eluting and everolimus-eluting coronary stents

artículo científico publicado en 2010

Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases

artículo científico publicado en 2004

DNA copy number alterations mark disease progression in paediatric chronic myeloid leukaemia

artículo científico publicado en 2014

Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy.

artículo científico publicado en 2009

Distinct kinetic and mechanical properties govern ALCAM-mediated interactions as shown by single-molecule force spectroscopy

artículo científico publicado en 2007

Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth.

artículo científico publicado en 1997

Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes

artículo científico publicado en 2011

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression

artículo científico publicado en 2007

Human and murine model cell lines for dendritic cell biology evaluated

artículo científico publicado en 2008

Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

artículo científico publicado en 2015

Impact of overlapping newer generation drug-eluting stents on clinical and angiographic outcomes: pooled analysis of five trials from the international Global RESOLUTE Program

artículo científico publicado en 2013

Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.

artículo científico publicado en 2014

Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia

artículo científico publicado en 2010

Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.

artículo científico publicado en 2015

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

artículo científico publicado en 2013

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells

artículo científico publicado en 2006

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

artículo científico publicado en 2008

Mechanoregulation of cytoskeletal dynamics by TRP channels

artículo científico publicado en 2012

Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells

artículo científico publicado en 2004

Myosin II and mechanotransduction: a balancing act.

artículo científico publicado en 2007

Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer

artículo científico publicado en 1995

Organization of the integrin LFA-1 in nanoclusters regulates its activity

artículo científico publicado en 2006

PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA-Rho-kinase axis

artículo científico publicado en 2008

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1

artículo científico publicado en 2003

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

artículo científico publicado en 1999

Regulation of MYCN expression in human neuroblastoma cells.

artículo científico publicado en 2009

Revertant somatic mosaicism by mitotic recombination in dyskeratosis congenita.

artículo científico publicado en 2012

TLR4-mediated podosome loss discriminates gram-negative from gram-positive bacteria in their capacity to induce dendritic cell migration and maturation

artículo científico publicado en 2009

TRPM7 is required for breast tumor cell metastasis

artículo científico publicado en 2012

TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation

artículo científico publicado en 2008

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells

artículo científico publicado en 2013

TRPM7, a novel regulator of actomyosin contractility and cell adhesion

artículo científico publicado en 2006

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

artículo científico publicado en 2015

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

artículo científico publicado en 1997

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution ⬇️

artículo científico publicado el 16 de febrero de 2012

The alpha-kinase family: an exceptional branch on the protein kinase tree.

artículo científico publicado en 2009

The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.

artículo científico publicado en 2008

The dishevelled protein is modified by wingless signaling in Drosophila

scientific journal article

Tumor suppressors BTG1 and BTG2: Beyond growth control

artículo científico publicado en 2019

Vascular Smooth Muscle Cell Differentiation to an Osteogenic Phenotype Involves TRPM7 Modulation by Magnesium

artículo científico publicado en 2010

Lista de obras de Frank N van Leeuwen

A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment

A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics

Activation of TRPM7 channels by phospholipase C-coupled receptor agonists

B-lineage transcription factors and cooperating gene lesions required for leukemia development

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells

Clinical outcomes after zotarolimus and everolimus drug eluting stent implantation in coronary artery bifurcation lesions: insights from the RESOLUTE All Comers Trial

Comparison of zotarolimus-eluting and everolimus-eluting coronary stents

Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases

DNA copy number alterations mark disease progression in paediatric chronic myeloid leukaemia

Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy.

Distinct kinetic and mechanical properties govern ALCAM-mediated interactions as shown by single-molecule force spectroscopy

Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth.

Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression

Human and murine model cell lines for dendritic cell biology evaluated

Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

Impact of overlapping newer generation drug-eluting stents on clinical and angiographic outcomes: pooled analysis of five trials from the international Global RESOLUTE Program

Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.

Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia

Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

Mechanoregulation of cytoskeletal dynamics by TRP channels

Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells

Myosin II and mechanotransduction: a balancing act.

Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer

Organization of the integrin LFA-1 in nanoclusters regulates its activity

PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA-Rho-kinase axis

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1

Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

Regulation of MYCN expression in human neuroblastoma cells.

Revertant somatic mosaicism by mitotic recombination in dyskeratosis congenita.

TLR4-mediated podosome loss discriminates gram-negative from gram-positive bacteria in their capacity to induce dendritic cell migration and maturation

TRPM7 is required for breast tumor cell metastasis

TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells

TRPM7, a novel regulator of actomyosin contractility and cell adhesion

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution ⬇️

The alpha-kinase family: an exceptional branch on the protein kinase tree.

The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.

The dishevelled protein is modified by wingless signaling in Drosophila

Tumor suppressors BTG1 and BTG2: Beyond growth control

Vascular Smooth Muscle Cell Differentiation to an Osteogenic Phenotype Involves TRPM7 Modulation by Magnesium