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Lista de obras de Jeffrey N Weiser

Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens

scientific article published in 2023

Age-related differences in IL-1 signaling and capsule serotype affect persistence of Streptococcus pneumoniae colonization

artículo científico publicado en 2018

Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage

artículo científico publicado en 2016

An Infant Mouse Model of Influenza Virus Transmission Demonstrates the Role of Virus-Specific Shedding, Humoral Immunity, and Sialidase Expression by Colonizing Streptococcus pneumoniae

article

Antibody-enhanced pneumococcal adherence requires IgA1 protease.

artículo científico publicado en 2003

Antigenic similarities in lipopolysaccharides of Haemophilus and Neisseria and expression of a digalactoside structure also present on human cells

artículo científico publicado en 1990

Bacterial colonization of nasal mucosa induces expression of siderocalin, an iron-sequestering component of innate immunity

artículo científico publicado en 2005

Bacterial exploitation of phosphorylcholine mimicry suppresses inflammation to promote airway infection.

artículo científico publicado en 2015

Bacteriocin activity of Streptococcus pneumoniae is controlled by the serine protease HtrA via posttranscriptional regulation

artículo científico publicado en 2008

Binding of human factor H to outer membrane protein P5 of non-typeable Haemophilus influenzae contributes to complement resistance

artículo científico publicado en 2014

Capsule Type and Amount Affect Shedding and Transmission of Streptococcus pneumoniae

artículo científico publicado en 2017

Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance.

artículo científico publicado en 2006

Capsule prolongs survival of Streptococcus pneumoniae during starvation.

artículo científico publicado en 2018

Characterization of repetitive sequences controlling phase variation of Haemophilus influenzae lipopolysaccharide

artículo científico publicado en 1990

Characterization of the phosphocholine-substituted oligosaccharide in lipopolysaccharides of type b Haemophilus influenzae

artículo científico publicado en 2000

Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking

artículo científico publicado en 2015

Co-infection subverts mucosal immunity in the upper respiratory tract

artículo científico publicado el 2 de junio de 2012

Coinfection with Streptococcus pneumoniae modulates the B cell response to influenza virus

artículo científico publicado en 2014

Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters

artículo científico publicado en 2011

Cross-protective mucosal immunity mediated by memory Th17 cells against Streptococcus pneumoniae lung infection.

scientific article published on 27 April 2016

Cross-reactivity of human immunoglobulin G2 recognizing phosphorylcholine and evidence for protection against major bacterial pathogens of the human respiratory tract

artículo científico publicado en 2004

Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniae

artículo científico publicado en 2006

Early bacterial colonization induces toll-like receptor-dependent transforming growth factor beta signaling in the epithelium.

artículo científico publicado en 2009

Effect of pneumococcal polysaccharide vaccine on nonbacteremic pneumococcal pneumonia

artículo científico publicado en 2007

Epithelial cells are sensitive detectors of bacterial pore-forming toxins

artículo científico publicado en 2006

Evasion of killing by human antibody and complement through multiple variations in the surface oligosaccharide of Haemophilus influenzae.

artículo científico

Factors contributing to hydrogen peroxide resistance in Streptococcus pneumoniae include pyruvate oxidase (SpxB) and avoidance of the toxic effects of the fenton reaction

artículo científico publicado en 2003

Fast and flexible bacterial genomic epidemiology with PopPUNK

artículo científico publicado en 2019

Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.

artículo científico publicado en 2005

Host-to-Host Transmission of Streptococcus pneumoniae Is Driven by Its Inflammatory Toxin, Pneumolysin.

artículo científico publicado en 2017

Human neutrophils kill Streptococcus pneumoniae via serine proteases.

artículo científico publicado en 2009

Identification of Pneumococcal Factors Affecting Pneumococcal Shedding Shows that the dlt Locus Promotes Inflammation and Transmission

scientific article published on 18 June 2019

Identification of the targets of cross-reactive antibodies induced by Streptococcus pneumoniae colonization.

artículo científico publicado en 2010

Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis.

artículo científico publicado en 2007

Increased chain length promotes pneumococcal adherence and colonization

artículo científico publicado en 2012

Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source.

artículo científico publicado en 2014

Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis

artículo científico publicado en 2011

Interaction of lipocalin 2, transferrin, and siderophores determines the replicative niche of Klebsiella pneumoniae during pneumonia.

artículo científico publicado en 2012

Interleukin-8 secretion in response to aferric enterobactin is potentiated by siderocalin

artículo científico publicado en 2007

Intracellular sensors of extracellular bacteria

artículo científico

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

scholarly article

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis

artículo científico publicado en 2019

Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2

artículo científico publicado en 2011

Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization

artículo científico publicado en 2004

Live attenuated Streptococcus pneumoniae strains induce serotype-independent mucosal and systemic protection in mice.

artículo científico publicado en 2007

MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.

artículo científico publicado en 2012

Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization

artículo científico publicado en 2014

Mechanisms of Bacterial Colonization of the Respiratory Tract

artículo científico publicado en 2015

Microbial modulation of host immunity with the small molecule phosphorylcholine

artículo científico publicado en 2012

Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody

artículo científico publicado en 2011

Modifications to the peptidoglycan backbone help bacteria to establish infection

artículo científico publicado en 2010

Mucosal clearance of capsule-expressing bacteria requires both TLR and nucleotide-binding oligomerization domain 1 signaling

artículo científico publicado en 2008

Mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin

artículo científico publicado en 2009

Multiple mechanisms for choline transport and utilization in Haemophilus influenzae

artículo científico publicado en 2003

Natural antibody to conserved targets of Haemophilus influenzae limits colonization of the murine nasopharynx.

artículo científico publicado en 2009

Neuraminidase expressed by Streptococcus pneumoniae desialylates the lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae: a paradigm for interbacterial competition among pathogens of the human respiratory tract

artículo científico publicado en 2002

Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae

artículo científico publicado en 2008

Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria

artículo científico publicado en 2007

Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing

artículo científico publicado en 2007

Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice.

artículo científico publicado en 2011

Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis

artículo científico publicado en 2016

Phase variable desialylation of host proteins that bind to Streptococcus pneumoniae in vivo and protect the airway

artículo científico publicado en 2004

Phase-variable lipopolysaccharide structures enhance the invasive capacity of Haemophilus influenzae

artículo científico publicado en 1990

Pneumococcal quorum sensing drives an asymmetric owner-intruder competitive strategy during carriage via the competence regulon

artículo científico publicado en 2019

Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection

scientific article published on 27 November 2019

Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease

artículo científico publicado en 2014

Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenase

artículo científico publicado en 2012

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

artículo científico publicado en 2010

Regenerative therapy based on miRNA-302 mimics for enhancing host recovery from pneumonia caused by Streptococcus pneumoniae

scientific article published on 10 April 2019

Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae

artículo científico publicado en 2008

Role of p38 MAP kinase and transforming growth factor-beta signaling in transepithelial migration of invasive bacterial pathogens

artículo científico publicado en 2007

Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance.

artículo científico publicado en 2015

Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant

artículo científico publicado en 2019

Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization

artículo científico publicado en 2003

Shielding of a lipooligosaccharide IgM epitope allows evasion of neutrophil-mediated killing of an invasive strain of nontypeable Haemophilus influenzae

artículo científico publicado en 2014

Short-sequence tandem and nontandem DNA repeats and endogenous hydrogen peroxide production contribute to genetic instability of Streptococcus pneumoniae

artículo científico publicado en 2002

Streptococcus pneumoniae Transmission Is Blocked by Type-Specific Immunity in an Infant Mouse Model

artículo científico publicado en 2017

Streptococcus pneumoniae resistance to complement-mediated immunity is dependent on the capsular serotype

artículo científico publicado en 2009

Streptococcus pneumoniae: transmission, colonization and invasion.

artículo científico publicado en 2018

Structural studies of the saccharide part of the cell envelope lipopolysaccharide from Haemophilus influenzae strain AH1-3 (lic3+)

artículo científico publicado en 1993

Synergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfaces

artículo científico publicado en 2005

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

artículo científico publicado en 2011

TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model

artículo científico publicado en 2014

The atypical amino-terminal LPNTG-containing domain of the pneumococcal human IgA1-specific protease is required for proper enzyme localization and function

artículo científico publicado en 2006

The battle with the host over microbial size

artículo científico publicado el 8 de febrero de 2013

The blp bacteriocins of Streptococcus pneumoniae mediate intraspecies competition both in vitro and in vivo.

artículo científico publicado en 2006

The immune response to pneumococcal proteins during experimental human carriage

artículo científico publicado en 2002

The immunological mechanisms that control pneumococcal carriage.

artículo científico publicado en 2017

The inhibitory effect of C-reactive protein on bacterial phosphorylcholine platelet-activating factor receptor-mediated adherence is blocked by surfactant

artículo científico publicado en 2002

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

artículo científico publicado en 2014

The molecular mechanism of phase variation of H. influenzae lipopolysaccharide

artículo científico publicado en 1989

The neonatal window of opportunity-early priming for life.

artículo científico publicado en 2017

The pneumococcus: why a commensal misbehaves

artículo científico publicado en 2009

The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces

artículo científico publicado en 2005

Three surface exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, promote resistance to opsonophagocytic killing by human neutrophils

artículo científico publicado en 2010

Tolerance of a phage element by Streptococcus pneumoniae leads to a fitness defect during colonization

artículo científico publicado en 2014

Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung

artículo científico publicado en 2002

Transcriptional profile of the Escherichia coli response to the antimicrobial insect peptide cecropin A.

artículo científico publicado en 2003

Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae β-galactosidase, BgaA

artículo científico publicado en 2014

Within-host competition drives selection for the capsule virulence determinant of Streptococcus pneumoniae

artículo científico publicado en 2010

beta-Defensin 1 contributes to pulmonary innate immunity in mice

scientific journal article

pyseer: a comprehensive tool for microbial pangenome-wide association studies

scientific article published on 01 December 2018