Lista de obras - Terence W Spithill - Dominio Público Uruguay

A bicistronic DNA vaccine containing apical membrane antigen 1 and merozoite surface protein 4/5 can prime humoral and cellular immune responses and partially protect mice against virulent Plasmodium chabaudi adami DS malaria.

scientific article published on October 2004

A family of heat shock protein 70-related genes are expressed in the promastigotes of Leishmania major

artículo científico publicado en 1989

A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation.

artículo científico publicado en 2010

A novel member of the NK-lysin protein family is developmentally regulated and secreted by Fasciola hepatica.

artículo científico publicado en 2000

A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implications

artículo científico publicado en 2011

Acquisition of resistance against Fasciola gigantica by Indonesian thin tail sheep.

artículo científico publicado en 1997

Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles

artículo científico publicado en 2010

Altered mitochondrial ribosomes in a cold-sensitive mutant of Saccharomyces cerevisiae

artículo científico publicado en 1978

An antigenically distinct lipophosphoglycan on amastigotes of Leishmania major

artículo científico publicado en 1991

Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1–P4 specificity reveals an unusual preference

article

Antibody-dependent cell-mediated cytotoxicity to newly excysted juvenile Fasciola hepatica in vitro is mediated by reactive nitrogen intermediates

scientific article published on 01 September 2001

Attempted immunisation of sheep against Fasciola hepatica using gamma-irradiated metacercariae

artículo científico publicado en 1995

Biochemical analysis of recombinant glutathione S-transferase of Fasciola hepatica

scientific article published on 01 February 1995

Biochemical and molecular characterization of Leishmania pifanoi amastigotes in continuous axenic culture

scientific article published on 01 November 1991

Biogenesis of mitochondria 48: mikamycin resistance in Saccharomyces cerevisiae--a mitochondrial mutation conferring resistance to an antimycin A-like contaminant in mikamycin

artículo científico publicado en 1977

Biogenesis of mitochondria 51: biochemical characterization of a mitochondrial mutation in Saccharomyces cerevisiae affecting the mitochondrial ribosome by conferring resistance to aminoglycoside antibiotics

artículo científico publicado en 1979

Biogenesis of mitochondria. The effects of altered membrane lipid composition on cation transport by mitochondria of Saccharomyces cerevisiae

artículo científico publicado en 1973

Cathepsin B proteases of flukes: the key to facilitating parasite control?

artículo científico publicado en 2010

Characterisation of a novel Kunitz-type molecule from the trematode Fasciola hepatica

scientific article published on 01 October 1995

Characterisation of humoral immune responses in dogs vaccinated with irradiated Ancylostoma caninum.

artículo científico publicado en 2003

Characterization of integral membrane proteins of Leishmania major by Triton X-114 fractionation and analysis of vaccination effects in mice

artículo científico publicado en 1989

Characterization of isolates and clones of Leishmania by analysis of kinetoplast DNA

scientific article published on 01 January 1984

Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.

artículo científico publicado en 2008

Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection.

artículo científico publicado en 2003

Comparative kinetics of serological and coproantigen ELISA and faecal egg count in cattle experimentally infected with Fasciola hepatica and following treatment with triclabendazole.

artículo científico publicado en 2013

Confirmation of Fasciola hepatica resistant to triclabendazole in naturally infected Australian beef and dairy cattle

artículo científico publicado en 2013

Confronting parasites from Canada

artículo científico publicado en 2002

Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase

artículo científico publicado en 1997

DNA vaccines and their application against parasites--promise, limitations and potential solutions.

artículo científico publicado en 2004

DNA vaccines in sheep: CTLA-4 mediated targeting and CpG motifs enhance immunogenicity in a DNA prime/protein boost strategy

artículo científico publicado en 2005

Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters.

artículo científico publicado en 1998

Editorial – ICOPA down under

artículo científico publicado en 2010

Evaluation of antigens of Fasciola gigantica as vaccines against tropical fasciolosis in cattle.

artículo científico publicado en 1997

Evidence for high genetic diversity of NAD1 and COX1 mitochondrial haplotypes among triclabendazole resistant and susceptible populations and field isolates of Fasciola hepatica (liver fluke) in Australia.

artículo científico publicado en 2013

Examination of variables in the vaccination of mice against cutaneous leishmaniasis using living avirulent cloned lines and killed promastigotes of Leishmania major

article by G F Mitchell et al published 1 December 1985 in International Journal for Parasitology

Exploring the Fasciola hepatica tegument proteome

artículo científico publicado en 2011

Fasciola hepatica and Fasciola gigantica: cloning and characterisation of 70 kDa heat-shock proteins reveals variation in HSP70 gene expression between parasite species recovered from sheep.

artículo científico publicado en 2007

Fasciola hepatica cathepsin L suppresses sheep lymphocyte proliferation in vitro and modulates surface CD4 expression on human and ovine T cells

artículo científico publicado en 2002

Fasciola hepatica: Characterization and Cloning of the Major Cathepsin B Protease Secreted by Newly Excysted Juvenile Liver Fluke ⬇️

artículo científico publicado el 1 de febrero de 1998

Fasciola hepatica: irradiation-induced alterations in carbohydrate and cathepsin-B protease expression in newly excysted juvenile liver fluke

scientific article published on 01 July 1996

Fasciola hepatica: localisation of glutathione S-transferase isoenzymes in adult and juvenile liver fluke

artículo científico publicado en 1995

Fasciola hepatica: stage-specific expression of novel gene sequences as identified by differential display.

artículo científico publicado en 1998

Fasciola: kinetics and quality of humoral responses to fatty acid binding protein and cathepsin l following delivery as DNA vaccines in mice

artículo científico publicado en 2001

First insight into CD59-like molecules of adult Fasciola hepatica

scientific article published on 21 June 2014

Genomic organization, chromosomal location and transcription of dispersed and repeated tubulin genes in Leishmania major

scientific article published on 01 May 1987

Genomics-based drug design targets the AT-rich malaria parasite: implications for antiparasite chemotherapy

artículo científico publicado en 2007

Glutathione S-transferase. Novel vaccine against Fasciola hepatica infection in sheep

artículo científico publicado en 1990

High prevalence of fasciolosis and evaluation of drug efficacy against Fasciola hepatica in dairy cattle in the Maffra and Bairnsdale districts of Gippsland, Victoria, Australia

artículo científico publicado en 2015

Host responses during experimental infection with Fasciola gigantica and Fasciola hepatica in Merino sheep II. Development of a predictive index for Fasciola gigantica worm burden

artículo científico publicado en 2008

Host responses during experimental infection with Fasciola gigantica or Fasciola hepatica in Merino sheep I. Comparative immunological and plasma biochemical changes during early infection

artículo científico publicado en 2006

Human fasciolosis acquired in an Australian urban setting

artículo científico publicado en 2003

Humoral responses in mice following vaccination with DNA encoding glutathione S-transferase of Fasciola hepatica: effects of mode of vaccination and the cellular compartment of antigen expression

article

Identification of 3-hydroxyproline residues in several proteins of Fasciola hepatica

artículo científico publicado en 1996

Identification of maxicircle DNA sequences in Leishmania Tarentolae that are homologous to sequences of specific yeast mitochondrial structural genes

scientific article published on 01 October 1982

Identification of novel diagnostic serum biomarkers for Chagas' disease in asymptomatic subjects by mass spectrometric profiling

artículo científico publicado en 2010

Identification of species, strains and clones of Leishmania by characterization of kinetoplast DNA minicircles

artículo científico publicado en 1984

Identification of two allelic forms of ovine CD4 exhibiting a Ser183/Pro183 polymorphism in the coding sequence of domain 3.

artículo científico publicado en 2006

Identification, expression and immunolocalization of cathepsin B3, a stage-specific antigen expressed by juvenile Fasciola gigantica.

artículo científico publicado en 2009

Immune responses in Indonesian thin tail and Merino sheep during a primary infection with Fasciola gigantica: lack of a specific IgG2 antibody response is associated with increased resistance to infection in Indonesian sheep.

artículo científico publicado en 1999

Immunological approaches for the control of fasciolosis

artículo científico publicado en 1997

Inability to reproduce protection against Teladorsagia circumcincta in sheep with a purified stage-specific 31 kDa antigen complex

scientific article published on 01 January 1995

Induction of specific T-cell responses, opsonizing antibodies, and protection against Plasmodium chabaudi adami infection in mice vaccinated with genomic expression libraries expressed in targeted and secretory DNA vectors

artículo científico publicado en 2003

Induction of strain-transcending immunity against Plasmodium chabaudi adami malaria with a multiepitope DNA vaccine

artículo científico publicado en 2005

Inhibitory effects of chloramphenicol isomers and other antibiotics on protein synthesis and respiration in procyclic Trypanosoma brucei brucei

artículo científico publicado en 1981

Is SELDI-TOF a valid tool for diagnostic biomarkers?

artículo científico publicado en 2010

Isolation and characterization of infective and non-infective clones of Leishmania tropica

artículo científico publicado en 1983

Isolation, cloning, and expression of fatty-acid binding proteins from Fasciola gigantica.

artículo científico publicado en 1997

Juvenile Fasciola hepatica are resistant to killing in vitro by free radicals compared with larvae of Schistosoma mansoni.

artículo científico publicado en 2000

Leishmania major and L. donovani: a method for rapid purification of amastigotes

artículo científico publicado en 1990

Leishmania major: expression and gene structure of the glycoprotein 63 molecule in virulent and avirulent clones and strains

artículo científico publicado en 1990

Liver fluke vaccines in ruminants: strategies, progress and future opportunities.

artículo científico

Molecular characterization of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica

artículo científico publicado en 1992

Molecular characterization of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica

artículo científico publicado en 1993

Molecular karyotype of five species of Leishmania and analysis of gene locations and chromosomal rearrangements

artículo científico publicado en 1987

Mutations of the mitochondrial DNA of Saccharomyces cerevisiae which affect the interaction between mitochondrial ribosomes and the inner mitochondrial membrane

artículo científico publicado en 1978

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages

scientific article published on 01 December 1986

Peritoneal lavage cells of Indonesian thin-tail sheep mediate antibody-dependent superoxide radical cytotoxicity in vitro against newly excysted juvenile Fasciola gigantica but not juvenile Fasciola hepatica

artículo científico publicado en 2007

Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent

artículo científico publicado en 2008

Primary sequence heterogeneity and tissue expression of glutathione S-transferases of Fasciola hepatica

artículo científico publicado en 1992

Production and processing of a recombinant Fasciola hepatica cathepsin B-like enzyme (FhcatB1) reveals potential processing mechanisms in the parasite

artículo científico publicado en 2006

Protection of cattle against Fasciola hepatica infection by vaccination with glutathione S-transferase

artículo científico publicado en 1996

RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro

artículo científico publicado en 2014

Resistance and susceptibility of mice to Leishmania major: a view from Melbourne

artículo científico publicado en 1987

Resistance of Indonesian thin tail sheep against Fasciola gigantica and F. hepatica.

artículo científico publicado en 1997

Sequence of a cDNA for the ND1 gene from Leishmania major: potential uridine addition in the polyadenosine tail

artículo científico publicado en 1989

The A/T-specific DNA alkylating agent adozelesin inhibits Plasmodium falciparum growth in vitro and protects mice against Plasmodium chabaudi adami infection

artículo científico publicado en 2006

The T687G SNP in a P-glycoprotein gene of Fasciola hepatica is not associated with resistance to triclabendazole in two resistant Australian populations

artículo científico publicado en 2014

The developmentally regulated P100/11E gene of Leishmania major shows homology to a superfamily of reductase genes

artículo científico publicado en 1989

The evolution of enzyme specificity in Fasciola spp.

artículo científico publicado en 2003

The kinetoplast DNA of the hemoflagellate protozoa.

artículo científico publicado en 1980

The protective efficacy of MSP4/5 against lethal Plasmodium chabaudi adami challenge is dependent on the type of DNA vaccine vector and vaccination protocol

artículo científico publicado en 2003

The secreted cathepsin L-like proteinases of the trematode, Fasciola hepatica, contain 3-hydroxyproline residues

artículo científico publicado en 1994

The sensitivity and specificity of two methods for detecting Fasciola infections in cattle

artículo científico publicado en 1999

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration.

artículo científico publicado en 2007

Use of multiplexed tandem PCR to estimate the prevalence and intensity of Theileria orientalis infections in cattle

artículo científico publicado en 2015

Vaccination against cutaneous leishmaniasis in mice using nonpathogenic cloned promastigotes of Leishmania major and importance of route of injection

artículo científico publicado en 1984

Vaccination against fasciolosis by a multivalent vaccine of stage-specific antigens

artículo científico publicado en 2008

Vaccination of sheep against Fasciola hepatica with glutathione S-transferase. Identification and mapping of antibody epitopes on a three-dimensional model of the antigen

scientific article published on 01 February 1994

Vaccination with a Plasmodium chabaudi adami multivalent DNA vaccine cross-protects A/J mice against challenge with P. c. adami DK and virulent Plasmodium chabaudi chabaudi AS parasites

artículo científico publicado en 2007

Variants of a Leishmania surface antigen derived from a multigenic family

artículo científico publicado en 1991

Lista de obras de Terence W Spithill

A bicistronic DNA vaccine containing apical membrane antigen 1 and merozoite surface protein 4/5 can prime humoral and cellular immune responses and partially protect mice against virulent Plasmodium chabaudi adami DS malaria.

A family of heat shock protein 70-related genes are expressed in the promastigotes of Leishmania major

A novel achiral seco-cyclopropylpyrido[e]indolone (CPyI) analog of CC-1065 and the duocarmycins: synthesis, DNA interactions, in vivo anticancer and anti-parasitic evaluation.

A novel member of the NK-lysin protein family is developmentally regulated and secreted by Fasciola hepatica.

A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implications

Acquisition of resistance against Fasciola gigantica by Indonesian thin tail sheep.

Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles

Altered mitochondrial ribosomes in a cold-sensitive mutant of Saccharomyces cerevisiae

An antigenically distinct lipophosphoglycan on amastigotes of Leishmania major

Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1–P4 specificity reveals an unusual preference

Antibody-dependent cell-mediated cytotoxicity to newly excysted juvenile Fasciola hepatica in vitro is mediated by reactive nitrogen intermediates

Attempted immunisation of sheep against Fasciola hepatica using gamma-irradiated metacercariae

Biochemical analysis of recombinant glutathione S-transferase of Fasciola hepatica

Biochemical and molecular characterization of Leishmania pifanoi amastigotes in continuous axenic culture

Biogenesis of mitochondria 48: mikamycin resistance in Saccharomyces cerevisiae--a mitochondrial mutation conferring resistance to an antimycin A-like contaminant in mikamycin

Biogenesis of mitochondria 51: biochemical characterization of a mitochondrial mutation in Saccharomyces cerevisiae affecting the mitochondrial ribosome by conferring resistance to aminoglycoside antibiotics

Biogenesis of mitochondria. The effects of altered membrane lipid composition on cation transport by mitochondria of Saccharomyces cerevisiae

Cathepsin B proteases of flukes: the key to facilitating parasite control?

Characterisation of a novel Kunitz-type molecule from the trematode Fasciola hepatica

Characterisation of humoral immune responses in dogs vaccinated with irradiated Ancylostoma caninum.

Characterization of integral membrane proteins of Leishmania major by Triton X-114 fractionation and analysis of vaccination effects in mice

Characterization of isolates and clones of Leishmania by analysis of kinetoplast DNA

Chemical attenuation of Plasmodium berghei sporozoites induces sterile immunity in mice.

Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection.

Comparative kinetics of serological and coproantigen ELISA and faecal egg count in cattle experimentally infected with Fasciola hepatica and following treatment with triclabendazole.

Confirmation of Fasciola hepatica resistant to triclabendazole in naturally infected Australian beef and dairy cattle

Confronting parasites from Canada

Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase

DNA vaccines and their application against parasites--promise, limitations and potential solutions.

DNA vaccines in sheep: CTLA-4 mediated targeting and CpG motifs enhance immunogenicity in a DNA prime/protein boost strategy

Developmental expression of a Fasciola hepatica sequence homologous to ABC transporters.

Editorial – ICOPA down under

Evaluation of antigens of Fasciola gigantica as vaccines against tropical fasciolosis in cattle.

Evidence for high genetic diversity of NAD1 and COX1 mitochondrial haplotypes among triclabendazole resistant and susceptible populations and field isolates of Fasciola hepatica (liver fluke) in Australia.

Examination of variables in the vaccination of mice against cutaneous leishmaniasis using living avirulent cloned lines and killed promastigotes of Leishmania major

Exploring the Fasciola hepatica tegument proteome

Fasciola hepatica and Fasciola gigantica: cloning and characterisation of 70 kDa heat-shock proteins reveals variation in HSP70 gene expression between parasite species recovered from sheep.

Fasciola hepatica cathepsin L suppresses sheep lymphocyte proliferation in vitro and modulates surface CD4 expression on human and ovine T cells

Fasciola hepatica: Characterization and Cloning of the Major Cathepsin B Protease Secreted by Newly Excysted Juvenile Liver Fluke ⬇️

Fasciola hepatica: irradiation-induced alterations in carbohydrate and cathepsin-B protease expression in newly excysted juvenile liver fluke

Fasciola hepatica: localisation of glutathione S-transferase isoenzymes in adult and juvenile liver fluke

Fasciola hepatica: stage-specific expression of novel gene sequences as identified by differential display.

Fasciola: kinetics and quality of humoral responses to fatty acid binding protein and cathepsin l following delivery as DNA vaccines in mice

First insight into CD59-like molecules of adult Fasciola hepatica

Genomic organization, chromosomal location and transcription of dispersed and repeated tubulin genes in Leishmania major

Genomics-based drug design targets the AT-rich malaria parasite: implications for antiparasite chemotherapy

Glutathione S-transferase. Novel vaccine against Fasciola hepatica infection in sheep

High prevalence of fasciolosis and evaluation of drug efficacy against Fasciola hepatica in dairy cattle in the Maffra and Bairnsdale districts of Gippsland, Victoria, Australia

Host responses during experimental infection with Fasciola gigantica and Fasciola hepatica in Merino sheep II. Development of a predictive index for Fasciola gigantica worm burden

Host responses during experimental infection with Fasciola gigantica or Fasciola hepatica in Merino sheep I. Comparative immunological and plasma biochemical changes during early infection

Human fasciolosis acquired in an Australian urban setting

Humoral responses in mice following vaccination with DNA encoding glutathione S-transferase of Fasciola hepatica: effects of mode of vaccination and the cellular compartment of antigen expression

Identification of 3-hydroxyproline residues in several proteins of Fasciola hepatica

Identification of maxicircle DNA sequences in Leishmania Tarentolae that are homologous to sequences of specific yeast mitochondrial structural genes

Identification of novel diagnostic serum biomarkers for Chagas' disease in asymptomatic subjects by mass spectrometric profiling

Identification of species, strains and clones of Leishmania by characterization of kinetoplast DNA minicircles

Identification of two allelic forms of ovine CD4 exhibiting a Ser183/Pro183 polymorphism in the coding sequence of domain 3.

Identification, expression and immunolocalization of cathepsin B3, a stage-specific antigen expressed by juvenile Fasciola gigantica.

Immune responses in Indonesian thin tail and Merino sheep during a primary infection with Fasciola gigantica: lack of a specific IgG2 antibody response is associated with increased resistance to infection in Indonesian sheep.

Immunological approaches for the control of fasciolosis

Inability to reproduce protection against Teladorsagia circumcincta in sheep with a purified stage-specific 31 kDa antigen complex

Induction of specific T-cell responses, opsonizing antibodies, and protection against Plasmodium chabaudi adami infection in mice vaccinated with genomic expression libraries expressed in targeted and secretory DNA vectors

Induction of strain-transcending immunity against Plasmodium chabaudi adami malaria with a multiepitope DNA vaccine

Inhibitory effects of chloramphenicol isomers and other antibiotics on protein synthesis and respiration in procyclic Trypanosoma brucei brucei

Is SELDI-TOF a valid tool for diagnostic biomarkers?

Isolation and characterization of infective and non-infective clones of Leishmania tropica

Isolation, cloning, and expression of fatty-acid binding proteins from Fasciola gigantica.

Juvenile Fasciola hepatica are resistant to killing in vitro by free radicals compared with larvae of Schistosoma mansoni.

Leishmania major and L. donovani: a method for rapid purification of amastigotes

Leishmania major: expression and gene structure of the glycoprotein 63 molecule in virulent and avirulent clones and strains

Liver fluke vaccines in ruminants: strategies, progress and future opportunities.

Molecular characterization of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica

Molecular characterization of cDNA sequences encoding glutathione S-transferases of Fasciola hepatica

Molecular karyotype of five species of Leishmania and analysis of gene locations and chromosomal rearrangements

Mutations of the mitochondrial DNA of Saccharomyces cerevisiae which affect the interaction between mitochondrial ribosomes and the inner mitochondrial membrane

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages

Peritoneal lavage cells of Indonesian thin-tail sheep mediate antibody-dependent superoxide radical cytotoxicity in vitro against newly excysted juvenile Fasciola gigantica but not juvenile Fasciola hepatica

Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent

Primary sequence heterogeneity and tissue expression of glutathione S-transferases of Fasciola hepatica