Lista de obras - John S. Spencer - Dominio Público Uruguay

A bispecific antibody based assay shows potential for detecting tuberculosis in resource constrained laboratory settings

artículo científico publicado en 2012

A modified synthesis and serological evaluation of neoglycoproteins containing the natural disaccharide of PGL-I from Mycobacterium leprae

artículo científico publicado en 2010

A new Mycobacterium species causing diffuse lepromatous leprosy

artículo científico publicado en 2008

Analysis of antibody responses to Mycobacterium leprae phenolic glycolipid I, lipoarabinomannan, and recombinant proteins to define disease subtype-specific antigenic profiles in leprosy.

artículo científico publicado en 2010

Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6

artículo científico publicado en 2002

Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis

artículo científico publicado en 2016

Cell-mediated immune response to tuberculosis antigens: comparison of skin testing and measurement of in vitro gamma interferon production in whole-blood culture

artículo científico publicado en 2001

Characterization of defective I-A surface expression in a mixed isotype expressing murine B cell lymphoma: continued expression of E alpha d A beta d despite competition from restored A alpha d A beta d pairs

artículo científico publicado en 1992

Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen.

artículo científico publicado en 2018

Characterization of the secreted MPT53 antigen of Mycobacterium tuberculosis

artículo científico publicado en 2001

Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10.

artículo científico publicado en 2004

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

article

Continued proteomic analysis ofMycobacterium leprae subcellular fractions

article

Deciphering the proteomic profile of Mycobacterium leprae cell envelope

artículo científico publicado en 2008

Detection of lipoarabinomannan in urine and serum of HIV-positive and HIV-negative TB suspects using an improved capture-enzyme linked immuno absorbent assay and gas chromatography/mass spectrometry

article

Detection of the tuberculosis antigenic marker mannose-capped lipoarabinomannan in pretreated serum by surface-enhanced Raman scattering

artículo científico

Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c

artículo científico publicado en 2016

Erratum: Corrigendum: Comparative genomic and phylogeographic analysis of Mycobacterium leprae

scholarly article published in Nature Genetics

Evaluation of Immunodiagnostic Tests for Leprosy in Brazil, China and Ethiopia

artículo científico publicado en 2018

Evidence of hidden leprosy in a supposedly low endemic area of Brazil

artículo científico publicado en 2017

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

artículo científico publicado en 2018

Expression and characterization of recombinant interferon gamma (IFN-gamma) from the nine-banded armadillo (Dasypus novemcinctus) and its effect on Mycobacterium leprae-infected macrophages.

artículo científico publicado en 2008

Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae. ⬇️

artículo científico publicado en 2014

From genome-based in silico predictions to ex vivo verification of leprosy diagnosis

artículo científico publicado en 2009

Further biochemical characterization of Mycobacterium leprae laminin-binding proteins

artículo científico publicado en 2001

Gene expression profile and immunological evaluation of unique hypothetical unknown proteins of Mycobacterium leprae by using quantitative real-time PCR.

artículo científico publicado en 2012

Gene set signature of reversal reaction type I in leprosy patients

artículo científico publicado en 2013

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

artículo científico publicado en 2011

IL-10 and NOS2 modulate antigen-specific reactivity and nerve infiltration by T cells in experimental leprosy

artículo científico publicado en 2014

Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis

artículo científico publicado en 2008

Identification of an Immunomodulating Agent from Mycobacterium leprae

artículo científico publicado en 2005

Immunization against full-length protein and peptides from the Lutzomyia longipalpis sand fly salivary component maxadilan protects against Leishmania major infection in a murine model

artículo científico publicado en 2017

Immunological Characterization of Antigens Encoded by the RD1 Region of the Mycobacterium tuberculosis Genome

artículo científico publicado en 2001

Immunological characterization of novel secreted antigens of Mycobacterium tuberculosis.

artículo científico publicado en 2005

Importance of specimen pretreatment for the low-level detection of mycobacterial lipoarabinomannan in human serum

artículo científico publicado en 2016

Insight toward early diagnosis of leprosy through analysis of the developing antibody responses of Mycobacterium leprae-infected armadillos.

artículo científico publicado en 2010

Lateral flow assay for simultaneous detection of cellular- and humoral immune responses.

artículo científico publicado en 2011

Leprosy in Children

artículo científico publicado en 2017

Leprosy in a prison population: A new active search strategy and a prospective clinical analysis

scientific article published on 10 December 2020

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts

artículo científico publicado en 2014

Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal

artículo científico publicado en 2015

ML0405 and ML2331 are antigens of Mycobacterium leprae with potential for diagnosis of leprosy

artículo científico publicado en 2006

ML1419c peptide immunization induces Mycobacterium leprae-specific HLA-A*0201-restricted CTL in vivo with potential to kill live mycobacteria

artículo científico publicado en 2011

MTSA-10, the product of the Rv3874 gene of Mycobacterium tuberculosis, elicits tuberculosis-specific, delayed-type hypersensitivity in guinea pigs

artículo científico publicado en 2000

Monoclonal Antibodies Specific for Antigens Expressed by Rat Type II Alveolar Epithelial and Nonciliated Bronchiolar Cells

artículo científico publicado en 1989

Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach

artículo científico publicado en 2010

New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy

artículo científico publicado en 2012

O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection

artículo científico publicado en 2013

PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages

artículo científico publicado en 2013

Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy

artículo científico publicado en 2012

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae

artículo científico publicado en 2018

Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection

artículo científico publicado en 2005

Serodiagnostic potential of culture filtrate antigens of Mycobacterium tuberculosis

artículo científico publicado en 2000

Spatial analysis spotlighting early childhood leprosy transmission in a hyperendemic municipality of the Brazilian Amazon region

artículo científico publicado en 2014

Spatial epidemiology and serologic cohorts increase the early detection of leprosy

artículo científico publicado en 2015

The Carboxy Terminus of EmbC fromMycobacterium smegmatisMediates Chain Length Extension of the Arabinan in Lipoarabinomannan

artículo científico publicado en 2006

The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions

article

The level of PPD-specific IFN-gamma-producing CD4+ T cells in the blood predicts the in vivo response to PPD.

artículo científico publicado en 2006

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

artículo científico publicado en 2015

Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: A comparison of ELISA and a rapid diagnostic test

artículo científico publicado en 2017

Use of protein microarrays to define the humoral immune response in leprosy patients and identification of disease-state-specific antigenic profiles

artículo científico publicado en 2006

XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-γ by CD4 T cells and participates in granuloma stability

scientific article published on 15 August 2007

miRNome Expression Analysis Reveals New Players on Leprosy Immune Physiopathology

artículo científico publicado en 2018

Lista de obras de John S. Spencer

A bispecific antibody based assay shows potential for detecting tuberculosis in resource constrained laboratory settings

A modified synthesis and serological evaluation of neoglycoproteins containing the natural disaccharide of PGL-I from Mycobacterium leprae

A new Mycobacterium species causing diffuse lepromatous leprosy

Analysis of antibody responses to Mycobacterium leprae phenolic glycolipid I, lipoarabinomannan, and recombinant proteins to define disease subtype-specific antigenic profiles in leprosy.

Antigenic specificity of the Mycobacterium leprae homologue of ESAT-6

Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis

Cell-mediated immune response to tuberculosis antigens: comparison of skin testing and measurement of in vitro gamma interferon production in whole-blood culture

Characterization of defective I-A surface expression in a mixed isotype expressing murine B cell lymphoma: continued expression of E alpha d A beta d despite competition from restored A alpha d A beta d pairs

Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen.

Characterization of the secreted MPT53 antigen of Mycobacterium tuberculosis

Comparative analysis of B- and T-cell epitopes of Mycobacterium leprae and Mycobacterium tuberculosis culture filtrate protein 10.

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

Continued proteomic analysis ofMycobacterium leprae subcellular fractions

Deciphering the proteomic profile of Mycobacterium leprae cell envelope

Detection of lipoarabinomannan in urine and serum of HIV-positive and HIV-negative TB suspects using an improved capture-enzyme linked immuno absorbent assay and gas chromatography/mass spectrometry

Detection of the tuberculosis antigenic marker mannose-capped lipoarabinomannan in pretreated serum by surface-enhanced Raman scattering

Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c

Erratum: Corrigendum: Comparative genomic and phylogeographic analysis of Mycobacterium leprae

Evaluation of Immunodiagnostic Tests for Leprosy in Brazil, China and Ethiopia

Evidence of hidden leprosy in a supposedly low endemic area of Brazil

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

Expression and characterization of recombinant interferon gamma (IFN-gamma) from the nine-banded armadillo (Dasypus novemcinctus) and its effect on Mycobacterium leprae-infected macrophages.

Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae. ⬇️

From genome-based in silico predictions to ex vivo verification of leprosy diagnosis

Further biochemical characterization of Mycobacterium leprae laminin-binding proteins

Gene expression profile and immunological evaluation of unique hypothetical unknown proteins of Mycobacterium leprae by using quantitative real-time PCR.

Gene set signature of reversal reaction type I in leprosy patients

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

IL-10 and NOS2 modulate antigen-specific reactivity and nerve infiltration by T cells in experimental leprosy

Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis

Identification of an Immunomodulating Agent from Mycobacterium leprae

Immunization against full-length protein and peptides from the Lutzomyia longipalpis sand fly salivary component maxadilan protects against Leishmania major infection in a murine model

Immunological Characterization of Antigens Encoded by the RD1 Region of the Mycobacterium tuberculosis Genome

Immunological characterization of novel secreted antigens of Mycobacterium tuberculosis.

Importance of specimen pretreatment for the low-level detection of mycobacterial lipoarabinomannan in human serum

Insight toward early diagnosis of leprosy through analysis of the developing antibody responses of Mycobacterium leprae-infected armadillos.

Lateral flow assay for simultaneous detection of cellular- and humoral immune responses.

Leprosy in Children

Leprosy in a prison population: A new active search strategy and a prospective clinical analysis

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts

Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal

ML0405 and ML2331 are antigens of Mycobacterium leprae with potential for diagnosis of leprosy

ML1419c peptide immunization induces Mycobacterium leprae-specific HLA-A*0201-restricted CTL in vivo with potential to kill live mycobacteria

MTSA-10, the product of the Rv3874 gene of Mycobacterium tuberculosis, elicits tuberculosis-specific, delayed-type hypersensitivity in guinea pigs

Monoclonal Antibodies Specific for Antigens Expressed by Rat Type II Alveolar Epithelial and Nonciliated Bronchiolar Cells

Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach

New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy

O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection

PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages

Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae

Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection

Serodiagnostic potential of culture filtrate antigens of Mycobacterium tuberculosis

Spatial analysis spotlighting early childhood leprosy transmission in a hyperendemic municipality of the Brazilian Amazon region

Spatial epidemiology and serologic cohorts increase the early detection of leprosy

The Carboxy Terminus of EmbC fromMycobacterium smegmatisMediates Chain Length Extension of the Arabinan in Lipoarabinomannan

The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions

The level of PPD-specific IFN-gamma-producing CD4+ T cells in the blood predicts the in vivo response to PPD.

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: A comparison of ELISA and a rapid diagnostic test

Use of protein microarrays to define the humoral immune response in leprosy patients and identification of disease-state-specific antigenic profiles

XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-γ by CD4 T cells and participates in granuloma stability

miRNome Expression Analysis Reveals New Players on Leprosy Immune Physiopathology