Lista de obras - Yu Xia - Dominio Público Uruguay

A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome.

artículo científico publicado en 2017

A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human

artículo científico publicado en 2016

A computational framework for heparan sulfate sequencing using high-resolution tandem mass spectra

artículo científico publicado en 2014

A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein fur.

artículo científico publicado en 2014

A proteome-scale map of the human interactome network

artículo científico publicado en 2014

A reference map of the human binary protein interactome

scientific article published on 08 April 2020

Ab initio construction of protein tertiary structures using a hierarchical approach

artículo científico publicado en 2000

An inter-species protein-protein interaction network across vast evolutionary distance

artículo científico publicado en 2016

Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs

artículo científico publicado en 2004

Are transient protein-protein interactions more dispensable?

artículo científico publicado en 2022

Assessing the limits of genomic data integration for predicting protein networks

artículo científico publicado en 2005

Bioinformatics analysis of macrophages exposed to Porphyromonas gingivalis: implications in acute vs. chronic infections

artículo científico publicado en 2010

Consequences of domain insertion on sequence-structure divergence in a superfold

scientific article published on 19 August 2013

Convergent perturbation of the human domain-resolved interactome by viruses and mutations inducing similar disease phenotypes

artículo científico publicado en 2019

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies

artículo científico publicado en 2008

Design of an optimal Chebyshev-expanded discrimination function for globular proteins

artículo científico publicado en 2002

Design principles of molecular networks revealed by global comparisons and composite motifs

artículo científico publicado en 2006

Discovering causal signaling pathways through gene-expression patterns

artículo científico publicado en 2010

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

artículo científico publicado en 2007

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing

artículo científico

Estimating dispensable content in the human interactome

scientific article published on 19 July 2019

Finding local communities in protein networks

artículo científico publicado en 2009

Funnel-like organization in sequence space determines the distributions of protein stability and folding rate preferred by evolution

artículo científico publicado en 2004

Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network

artículo científico publicado en 2009

Haplotype-resolved de novo assembly of the Vero cell line genome

artículo científico publicado en 2021

Heterozygous yeast deletion collection screens reveal essential targets of Hsp90

artículo científico publicado en 2011

High-precision high-coverage functional inference from integrated data sources

artículo científico publicado en 2008

Independent effects of protein core size and expression on residue-level structure-evolution relationships

artículo científico publicado en 2012

Integrated assessment of genomic correlates of protein evolutionary rate

artículo científico publicado en 2009

Integrated prediction of the helical membrane protein interactome in yeast.

artículo científico publicado en 2006

Interactome evolution: insights from genome-wide analyses of protein-protein interactions

artículo científico publicado en 2017

Molecular modeling and design of invariant chain peptides with altered dissociation kinetics from class II MHC.

artículo científico publicado en 1996

Multi-edge gene set networks reveal novel insights into global relationships between biological themes

artículo científico publicado en 2012

Nature of Long-Range Evolutionary Constraint in Enzymes: Insights from Comparison to Pseudoenzymes with Similar Structures

scientific article published on 01 November 2018

Network Centrality Analysis in Fungi Reveals Complex Regulation of Lost and Gained Genes.

artículo científico publicado en 2017

Non-catalytic Binding Sites Induce Weaker Long-Range Evolutionary Rate Gradients than Catalytic Sites in Enzymes

artículo científico publicado en 2019

Precipitation patterns with polygonal boundaries between electrolytes

scientific article published on 13 October 2009

Predicting eukaryotic transcriptional cooperativity by Bayesian network integration of genome-wide data

artículo científico publicado en 2009

Quantitative residue-level structure-evolution relationships in the yeast membrane proteome

artículo científico publicado en 2013

Regulatory network structure as a dominant determinant of transcription factor evolutionary rate

artículo científico publicado en 2012

Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors.

artículo científico publicado en 2014

Roles of mutation and recombination in the evolution of protein thermodynamics

artículo científico publicado en 2002

Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor.

artículo científico publicado en 2004

Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms

artículo científico publicado en 2005

Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks.

artículo científico publicado en 2013

Simulating protein evolution in sequence and structure space

artículo científico publicado en 2004

Spectral affinity in protein networks

artículo científico publicado en 2009

Structural determinants of protein evolution are context-sensitive at the residue level

artículo científico publicado en 2009

Structural principles within the human-virus protein-protein interaction network.

artículo científico publicado en 2011

Structure-guided approach for detecting large domain inserts in protein sequences as illustrated using the haloacid dehalogenase superfamily.

artículo científico publicado en 2014

The Impact of Native State Switching on Protein Sequence Evolution.

artículo científico publicado en 2017

The role of disorder in interaction networks: a structural analysis

artículo científico publicado en 2008

Therapeutics of Ebola hemorrhagic fever: whole-genome transcriptional analysis of successful disease mitigation

artículo científico publicado en 2011

Transcriptional correlates of disease outcome in anticoagulant-treated non-human primates infected with ebolavirus

artículo científico publicado en 2014

Upon Accounting for the Impact of Isoenzyme Loss, Gene Deletion Costs Anticorrelate with Their Evolutionary Rates.

artículo científico publicado en 2017

Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation

artículo científico publicado en 2005

Using Pseudoenzymes to Probe Evolutionary Design Principles of Enzymes

artículo científico publicado en 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

artículo científico publicado en 2016

Widespread macromolecular interaction perturbations in human genetic disorders

scientific journal article

Lista de obras de Yu Xia

A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome.

A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human

A computational framework for heparan sulfate sequencing using high-resolution tandem mass spectra

A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein fur.

A proteome-scale map of the human interactome network

A reference map of the human binary protein interactome

Ab initio construction of protein tertiary structures using a hierarchical approach

An inter-species protein-protein interaction network across vast evolutionary distance

Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs

Are transient protein-protein interactions more dispensable?

Assessing the limits of genomic data integration for predicting protein networks

Bioinformatics analysis of macrophages exposed to Porphyromonas gingivalis: implications in acute vs. chronic infections

Consequences of domain insertion on sequence-structure divergence in a superfold

Convergent perturbation of the human domain-resolved interactome by viruses and mutations inducing similar disease phenotypes

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies

Design of an optimal Chebyshev-expanded discrimination function for globular proteins

Design principles of molecular networks revealed by global comparisons and composite motifs

Discovering causal signaling pathways through gene-expression patterns

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing

Estimating dispensable content in the human interactome

Finding local communities in protein networks

Funnel-like organization in sequence space determines the distributions of protein stability and folding rate preferred by evolution

Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network

Haplotype-resolved de novo assembly of the Vero cell line genome

Heterozygous yeast deletion collection screens reveal essential targets of Hsp90

High-precision high-coverage functional inference from integrated data sources

Independent effects of protein core size and expression on residue-level structure-evolution relationships

Integrated assessment of genomic correlates of protein evolutionary rate

Integrated prediction of the helical membrane protein interactome in yeast.

Interactome evolution: insights from genome-wide analyses of protein-protein interactions

Molecular modeling and design of invariant chain peptides with altered dissociation kinetics from class II MHC.

Multi-edge gene set networks reveal novel insights into global relationships between biological themes

Nature of Long-Range Evolutionary Constraint in Enzymes: Insights from Comparison to Pseudoenzymes with Similar Structures

Network Centrality Analysis in Fungi Reveals Complex Regulation of Lost and Gained Genes.

Non-catalytic Binding Sites Induce Weaker Long-Range Evolutionary Rate Gradients than Catalytic Sites in Enzymes

Precipitation patterns with polygonal boundaries between electrolytes

Predicting eukaryotic transcriptional cooperativity by Bayesian network integration of genome-wide data

Quantitative residue-level structure-evolution relationships in the yeast membrane proteome

Regulatory network structure as a dominant determinant of transcription factor evolutionary rate

Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors.

Roles of mutation and recombination in the evolution of protein thermodynamics

Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor.

Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms

Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks.

Simulating protein evolution in sequence and structure space

Spectral affinity in protein networks

Structural determinants of protein evolution are context-sensitive at the residue level

Structural principles within the human-virus protein-protein interaction network.

Structure-guided approach for detecting large domain inserts in protein sequences as illustrated using the haloacid dehalogenase superfamily.

The Impact of Native State Switching on Protein Sequence Evolution.

The role of disorder in interaction networks: a structural analysis

Therapeutics of Ebola hemorrhagic fever: whole-genome transcriptional analysis of successful disease mitigation

Transcriptional correlates of disease outcome in anticoagulant-treated non-human primates infected with ebolavirus

Upon Accounting for the Impact of Isoenzyme Loss, Gene Deletion Costs Anticorrelate with Their Evolutionary Rates.

Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation

Using Pseudoenzymes to Probe Evolutionary Design Principles of Enzymes

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

Widespread macromolecular interaction perturbations in human genetic disorders