Lista de obras - Jose Carlos Segovia - Dominio Público Uruguay

A comprehensive strategy for the subtyping of patients with Fanconi anaemia: conclusions from the Spanish Fanconi Anemia Research Network

artículo científico publicado en 2006

A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts

artículo científico

A simplified approach to improve the efficiency and safety of ex vivo hematopoietic gene therapy in fanconi anemia patients

artículo científico publicado en 2006

Altered T cell differentiation and Notch signaling induced by the ectopic expression of keratin K10 in the epithelial cells of the thymus

artículo científico publicado en 2005

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair

artículo científico publicado en 2009

Bone marrow-derived cells promote liver regeneration in mice with erythropoietic protoporphyria

artículo científico publicado en 2009

Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis

artículo científico publicado en 2006

Brief report: reduced expression of CD18 leads to the in vivo expansion of hematopoietic stem cells in mouse bone marrow.

artículo científico publicado en 2014

Cardiac Bmi1(+) cells contribute to myocardial renewal in the murine adult heart

artículo científico publicado en 2015

Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo.

artículo científico publicado en 2012

Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: a weak and efficient promoter for gene therapy

artículo científico publicado en 2007

Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

artículo científico publicado en 2007

Cytotoxic infection of hematopoietic stem and committed progenitor cells by the parvovirus minute virus of mice. Propagation of an acute myelosuppression in culture

artículo científico publicado en 1991

Development of lentiviral vectors with optimized transcriptional activity for the gene therapy of patients with Fanconi anemia

artículo científico publicado en 2010

Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis.

artículo científico publicado en 2015

Efficient engraftment of in utero transplanted mice with retrovirally transduced hematopoietic stem cells

artículo científico publicado en 2005

Engraftment and in vivo proliferation advantage of gene corrected mobilized CD34(+) cells from Fanconi anemia patients.

artículo científico

Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10

artículo científico publicado en 2021

Evolution to pathogenicity of the parvovirus minute virus of mice in immunodeficient mice involves genetic heterogeneity at the capsid domain that determines tropism.

artículo científico publicado en 2007

Ex vivo expansion of umbilical cord blood (UCB) CD34(+) cells alters the expression and function of alpha 4 beta 1 and alpha 5 beta 1 integrins

scientific article published on 01 October 2001

Functional analysis of gammaretroviral vector transduction by quantitative PCR.

artículo científico publicado en 2006

Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy

artículo científico publicado en 2014

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1

scientific journal article

Hematopoietic mobilization in mice increases the presence of bone marrow-derived hepatocytes via in vivo cell fusion

artículo científico publicado en 2006

Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation

scientific article published on 30 April 2020

Hydroxytyrosol Administration Enhances Atherosclerotic Lesion Development in Apo E Deficient Mice

artículo científico publicado en 2006

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

artículo científico publicado en 2008

IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice

artículo científico publicado en 2020

Immunoresponse against the transgene limits hematopoietic engraftment of mice transplanted in utero with virally transduced fetal liver.

artículo científico publicado en 2010

In comparison with palm oil, dietary nut supplementation delays the progression of atherosclerotic lesions in female apoE-deficient mice

artículo científico publicado en 2012

In vitro and in vivo expression of human erythrocyte pyruvate kinase in erythroid cells: a gene therapy approach.

artículo científico publicado en 2007

In vitro and in vivo susceptibility of mouse megakaryocytic progenitors to strain i of parvovirus minute virus of mice.

artículo científico publicado en 2001

In vitro myelosuppressive effects of the parvovirus minute virus of mice (MVMi) on hematopoietic stem and committed progenitor cells ⬇️

artículo científico publicado el 1 de marzo de 1991

In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells

artículo científico publicado en 2020

In vivo proliferation advantage of genetically corrected hematopoietic stem cells in a mouse model of Fanconi anemia FA-D1.

artículo científico publicado en 2008

Latent hematopoietic stem cell toxicity associated with protracted drug administration

artículo científico publicado en 2001

Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients

artículo científico publicado en 2009

Mesenchymal stromal cells enhance the engraftment of hematopoietic stem cells in an autologous mouse transplantation model

artículo científico publicado en 2015

New frontier in regenerative medicine: site-specific gene correction in patient-specific induced pluripotent stem cells

artículo científico publicado en 2013

Non-homologous end-joining defect in fanconi anemia hematopoietic cells exposed to ionizing radiation

artículo científico publicado en 2005

Nonviral transfer of genes to pig primary keratinocytes. Induction of angiogenesis by composite grafts of modified keratinocytes overexpressing VEGF driven by a keratin promoter

artículo científico publicado en 1999

Olive oil preparation determines the atherosclerotic protection in apolipoprotein E knockout mice

artículo científico publicado en 2006

Optimising stable retroviral transduction of primary human synovial fibroblasts.

artículo científico publicado en 2006

Parvovirus infection suppresses long-term repopulating hematopoietic stem cells

artículo científico publicado en 2003

Peritoneal repairing cells: a type of bone marrow derived progenitor cells involved in mesothelial regeneration

artículo científico publicado en 2010

Preserved long-term repopulation and differentiation properties of hematopoietic grafts subjected to ex vivo expansion with stem cell factor and interleukin 11

scientific article published on 01 May 1999

Purging of leukemia-contaminated bone marrow grafts using suicide adenoviral vectors: an in vivo murine experimental model.

artículo científico publicado en 2003

Regulatory elements of the vav gene drive transgene expression in hematopoietic stem cells from adult mice

artículo científico publicado en 2004

Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα.

artículo científico publicado en 2015

Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzyme

artículo científico publicado en 2009

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells

artículo científico publicado en 2002

Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax.

artículo científico publicado en 2013

Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice

artículo científico publicado en 2007

Targeted gene therapy into a safe harbor site in human hematopoietic progenitor cells

scientific article published on 26 March 2020

The NFKB Inducing Kinase Modulates Hematopoiesis During Stress

artículo científico publicado en 2015

The role of the vav promoter in gene therapy: Safer vectors with weaker and stable expression

article

Transplantation of syngenic bone marrow contaminated with NGFr-marked WEHI-3B cells: an improved model of leukemia relapse in mice

artículo científico publicado en 2000

Yohimbine prevents the effect of morphine on the redox status of neuroblastomaxglioma NG108-15 cells

artículo científico publicado en 2009

p73 plays a role in erythroid differentiation through GATA1 induction.

artículo científico publicado en 2009

Lista de obras de Jose Carlos Segovia

A comprehensive strategy for the subtyping of patients with Fanconi anaemia: conclusions from the Spanish Fanconi Anemia Research Network

A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts

A simplified approach to improve the efficiency and safety of ex vivo hematopoietic gene therapy in fanconi anemia patients

Altered T cell differentiation and Notch signaling induced by the ectopic expression of keratin K10 in the epithelial cells of the thymus

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair

Bone marrow-derived cells promote liver regeneration in mice with erythropoietic protoporphyria

Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis

Brief report: reduced expression of CD18 leads to the in vivo expansion of hematopoietic stem cells in mouse bone marrow.

Cardiac Bmi1(+) cells contribute to myocardial renewal in the murine adult heart

Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo.

Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: a weak and efficient promoter for gene therapy

Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

Cytotoxic infection of hematopoietic stem and committed progenitor cells by the parvovirus minute virus of mice. Propagation of an acute myelosuppression in culture

Development of lentiviral vectors with optimized transcriptional activity for the gene therapy of patients with Fanconi anemia

Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis.

Efficient engraftment of in utero transplanted mice with retrovirally transduced hematopoietic stem cells

Engraftment and in vivo proliferation advantage of gene corrected mobilized CD34(+) cells from Fanconi anemia patients.

Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10

Evolution to pathogenicity of the parvovirus minute virus of mice in immunodeficient mice involves genetic heterogeneity at the capsid domain that determines tropism.

Ex vivo expansion of umbilical cord blood (UCB) CD34(+) cells alters the expression and function of alpha 4 beta 1 and alpha 5 beta 1 integrins

Functional analysis of gammaretroviral vector transduction by quantitative PCR.

Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1

Hematopoietic mobilization in mice increases the presence of bone marrow-derived hepatocytes via in vivo cell fusion

Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation

Hydroxytyrosol Administration Enhances Atherosclerotic Lesion Development in Apo E Deficient Mice

IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice

Immunoresponse against the transgene limits hematopoietic engraftment of mice transplanted in utero with virally transduced fetal liver.

In comparison with palm oil, dietary nut supplementation delays the progression of atherosclerotic lesions in female apoE-deficient mice

In vitro and in vivo expression of human erythrocyte pyruvate kinase in erythroid cells: a gene therapy approach.

In vitro and in vivo susceptibility of mouse megakaryocytic progenitors to strain i of parvovirus minute virus of mice.

In vitro myelosuppressive effects of the parvovirus minute virus of mice (MVMi) on hematopoietic stem and committed progenitor cells ⬇️

In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells

In vivo proliferation advantage of genetically corrected hematopoietic stem cells in a mouse model of Fanconi anemia FA-D1.

Latent hematopoietic stem cell toxicity associated with protracted drug administration

Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients

Mesenchymal stromal cells enhance the engraftment of hematopoietic stem cells in an autologous mouse transplantation model

New frontier in regenerative medicine: site-specific gene correction in patient-specific induced pluripotent stem cells

Non-homologous end-joining defect in fanconi anemia hematopoietic cells exposed to ionizing radiation

Nonviral transfer of genes to pig primary keratinocytes. Induction of angiogenesis by composite grafts of modified keratinocytes overexpressing VEGF driven by a keratin promoter

Olive oil preparation determines the atherosclerotic protection in apolipoprotein E knockout mice

Optimising stable retroviral transduction of primary human synovial fibroblasts.

Parvovirus infection suppresses long-term repopulating hematopoietic stem cells

Peritoneal repairing cells: a type of bone marrow derived progenitor cells involved in mesothelial regeneration

Preserved long-term repopulation and differentiation properties of hematopoietic grafts subjected to ex vivo expansion with stem cell factor and interleukin 11

Purging of leukemia-contaminated bone marrow grafts using suicide adenoviral vectors: an in vivo murine experimental model.

Regulatory elements of the vav gene drive transgene expression in hematopoietic stem cells from adult mice

Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα.

Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzyme

Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells

Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax.

Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice

Targeted gene therapy into a safe harbor site in human hematopoietic progenitor cells

The NFKB Inducing Kinase Modulates Hematopoiesis During Stress

The role of the vav promoter in gene therapy: Safer vectors with weaker and stable expression

Transplantation of syngenic bone marrow contaminated with NGFr-marked WEHI-3B cells: an improved model of leukemia relapse in mice

Yohimbine prevents the effect of morphine on the redox status of neuroblastomaxglioma NG108-15 cells

p73 plays a role in erythroid differentiation through GATA1 induction.