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Lista de obras de Don J. Diamond

A functional recombinant single-chain T cell receptor fragment capable of selectively targeting antigen-presenting cells.

artículo científico publicado en 2002

A fusion protein of HCMV IE1 exon4 and IE2 exon5 stimulates potent cellular immunity in an MVA vaccine vector.

artículo científico publicado en 2008

A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models

artículo científico publicado en 2008

A road less traveled paved by IDO silencing: Harnessing the antitumor activity of neutrophils

artículo científico publicado en 2013

A vaccine based on the rhesus cytomegalovirus UL128 complex induces broadly neutralizing antibodies in rhesus macaques.

artículo científico publicado en 2012

Adaptive NK cell reconstitution is associated with better clinical outcomes

scholarly article by Frank Cichocki et al published 24 January 2019 in JCI insight

Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Tr

artículo científico publicado en 2015

An HLA-restricted, p53 specific immune response from HLA transgenic p53 knockout mice

artículo científico publicado el 1 de enero de 1998

An MVA vaccine overcomes tolerance to human p53 in mice and humans

artículo científico publicado en 2007

Assessment of cellular immunity to human cytomegalovirus in recipients of allogeneic stem cell transplants.

artículo científico publicado en 2004

Attenuated poxvirus expressing three immunodominant CMV antigens as a vaccine strategy for CMV infection.

artículo científico publicado en 2006

Attenuated poxviruses generate clinically relevant frequencies of CMV-specific T cells.

artículo científico publicado en 2004

CD154 expression is associated with neutralizing antibody titer levels postinfluenza vaccination in stem cell transplant patients and healthy adults

artículo científico publicado en 2010

CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT.

artículo científico publicado en 2015

CMVpp65 Vaccine Enhances the Antitumor Efficacy of Adoptively Transferred CD19-Redirected CMV-Specific T Cells.

artículo científico publicado en 2015

CTLA-4 blockade enhances the therapeutic effect of an attenuated poxvirus vaccine targeting p53 in an established murine tumor model

artículo científico publicado en 2003

Carbon nanotubes enhance CpG uptake and potentiate antiglioma immunity

artículo científico publicado en 2010

Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants

artículo científico publicado en 2002

Characterization of host immunity to cytomegalovirus pp150 (UL32).

artículo científico publicado en 2005

Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice

artículo científico publicado en 2011

Characterization of nuclear protein binding to the interferon-gamma promoter in quiescent and activated human T cells.

artículo científico publicado en 1992

Chimeric Antigen Receptors Targeting Human Cytomegalovirus

scientific article published on 13 April 2020

Clinical evaluation of safety and immunogenicity of PADRE-cytomegalovirus (CMV) and tetanus-CMV fusion peptide vaccines with or without PF03512676 adjuvant

artículo científico publicado en 2012

Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice

artículo científico publicado en 2017

Comparison of monovalent glycoprotein B with bivalent gB/pp65 (GP83) vaccine for congenital cytomegalovirus infection in a guinea pig model: Inclusion of GP83 reduces gB antibody response but both vaccine approaches provide equivalent protection aga

artículo científico publicado en 2015

Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab.

artículo científico publicado en 2017

Correction for Chiuppesi et al., "Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Responses against Human Cytomegalovirus in Mice"

artículo científico publicado en 2019

Cross-reactive CTL recognizing two HLA-A*02-restricted epitopes within the BK virus and JC virus VP1 polypeptides are frequent in immunocompetent individuals

artículo científico publicado en 2006

Cross-reactivity of T lymphocytes recognizing a human cytotoxic T-lymphocyte epitope within BK and JC virus VP1 polypeptides.

artículo científico publicado en 2005

Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection.

artículo científico publicado en 2005

Cytomegalovirus-vectored vaccines for HIV and other pathogens

artículo científico publicado en 2020

DNA and low titer, helper-free, recombinant AAV prime-boost vaccination for cytomegalovirus induces an immune response to CMV-pp65 and CMV-IE1 in transgenic HLA A*0201 mice

artículo científico publicado en 2004

DNA vaccine prime followed by boost with live attenuated virus significantly improves antigen-specific T cell responses against human cytomegalovirus.

artículo científico publicado en 2013

Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice

scientific article published on 06 September 2019

Detection and preliminary characterization of CD8+T lymphocytes specific for Wilms' tumor antigen in patients with non-Hodgkin lymphoma.

artículo científico publicado en 2013

Developing Effective Salmonella-based Approaches to Treat Pancreatic Cancer

artículo científico publicado en 2016

Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform

scientific article published on 17 July 2020

Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine

artículo científico publicado en 2020

Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform

artículo científico publicado en 2020

Development of a novel, guinea pig-specific IFN-γ ELISPOT assay and characterization of guinea pig cytomegalovirus GP83-specific cellular immune responses following immunization with a modified vaccinia virus Ankara (MVA)-vectored GP83 vaccine

artículo científico publicado en 2014

Effective cancer vaccine platform based on attenuated salmonella and a type III secretion system

artículo científico publicado en 2014

Effects of rat growth hormone (rGH)-releasing factor and somatostatin on the release and synthesis of rGH in dispersed pituitary cells.

artículo científico publicado en 1985

Enhancement of cancer vaccine therapy by systemic delivery of a tumor-targeting Salmonella-based STAT3 shRNA suppresses the growth of established melanoma tumors

artículo científico publicado en 2011

Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer

artículo científico publicado en 2016

Evaluation of recombinant modified vaccinia Ankara virus-based rhesus cytomegalovirus vaccines in rhesus macaques

artículo científico publicado en 2008

Evaluation of safety and efficacy of p53MVA vaccine combined with pembrolizumab in patients with advanced solid cancers

artículo científico publicado en 2018

Ex vivo detection of CD8 T cells specific for H-Y minor histocompatibility antigens in allogeneic hematopoietic stem cell transplant recipients

artículo científico publicado en 2014

Exciting Times for Cytomegalovirus (CMV) Vaccine Development: Navigating the Pathways toward the Goal of Protecting Infants against Congenital CMV Infection

scientific article published on 14 September 2020

Exploiting 2A Peptides to Elicit Potent Neutralizing Antibodies by a Multi-Subunit Herpesvirus Glycoprotein Complex

artículo científico publicado en 2017

Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults

artículo científico publicado en 2007

Functional comparison of T cells recognizing cytomegalovirus pp65 and intermediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients

artículo científico publicado en 2006

Heterologous prime/boost immunization with p53-based vaccines combined with toll-like receptor stimulation enhances tumor regression.

artículo científico publicado en 2010

Human cytomegalovirus proteins pp65 and immediate early protein 1 are common targets for CD8+ T cell responses in children with congenital or postnatal human cytomegalovirus infection

artículo científico publicado en 2004

Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex

artículo científico publicado en 2014

Human cytomegalovirus vaccine: time to look for alternative options.

artículo científico publicado en 2005

Human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy maintain activated CD8+ T cell subsets as a strong adaptive immune response to cytomegalovirus.

artículo científico publicado en 2001

Identification of a Continuous Neutralizing Epitope within UL128 of Human Cytomegalovirus

artículo científico publicado en 2017

Immunization with Th-CTL Fusion Peptide and Cytosine-Phosphate-Guanine DNA in Transgenic HLA-A2 Mice Induces Recognition of HIV-Infected T Cells and Clears Vaccinia Virus Challenge

artículo científico publicado el 15 de octubre de 2003

Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients

scientific article published on 15 April 2009

In vitro expansion of polyclonal T-cell subsets for adoptive immunotherapy by recombinant modified vaccinia Ankara

artículo científico

Increased programmed death-1 molecule expression in cytomegalovirus disease and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation

artículo científico publicado en 2009

Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response.

artículo científico publicado en 2000

Infrequent occurrence of natural mutations in the pp65(495-503) epitope sequence presented by the HLA A*0201 allele among human cytomegalovirus isolates

artículo científico publicado en 2001

Intergenic region 3 of modified vaccinia ankara is a functional site for insert gene expression and allows for potent antigen-specific immune responses

artículo científico publicado en 2010

Intracerebral CpG immunotherapy with carbon nanotubes abrogates growth of subcutaneous melanomas in mice

artículo científico publicado en 2012

La Rosa C et al (J Infect Dis 2012; 205:1294–304).

artículo científico publicado en 2013

Lack of association of cytomegalovirus with human brain tumors.

artículo científico publicado en 2005

Longitudinal assessment of cytomegalovirus (CMV)-specific immune responses in liver transplant recipients at high risk for late CMV disease

artículo científico publicado en 2007

MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults

artículo científico publicado en 2016

MVA-Vectored Pentameric Complex (PC) and gB Vaccines Improve Pregnancy Outcome after Guinea Pig CMV Challenge, but Only gB Vaccine Reduces Vertical Transmission

scientific article published on 14 November 2019

Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development

artículo científico publicado en 2009

Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

artículo científico publicado en 2015

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

artículo científico publicado en 2020

Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines

artículo científico publicado en 2009

Modified vaccinia Ankara expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model.

artículo científico publicado en 2010

Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Reponses against Human Cytomegalovirus in Mice

scholarly article by Flavia Chiuppesi et al published 1 October 2018 in Journal of Virology

Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial Cells

artículo científico publicado en 2017

Novel conjugates of epitope fusion peptides with CpG-ODN display enhanced immunogenicity and HIV recognition.

artículo científico publicado en 2005

Oblimersen and alpha-interferon in metastatic renal cancer: a phase II study of the California Cancer Consortium.

artículo científico publicado en 2007

Open reading frames carried on UL/b' are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys.

artículo científico publicado en 2011

Overcoming immunosuppression to enhance a p53MVA vaccine.

artículo científico publicado en 2014

Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection.

artículo científico publicado en 2012

Plasma IL-10 Levels to Guide Antiviral Prophylaxis Prevention of Late-Onset Cytomegalovirus Disease, in High Risk Solid Kidney and Liver Transplant Recipients

artículo científico publicado en 2016

Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission

artículo científico publicado en 2017

Population coverage by HLA class-I restricted cytotoxic T-lymphocyte epitopes.

artículo científico publicado en 2001

Poxvirus Vectored Cytomegalovirus Vaccine to Prevent Cytomegalovirus Viremia in Transplant Recipients: A Phase 2, Randomized Clinical Trial

artículo científico publicado en 2020

Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice.

artículo científico publicado en 2002

Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

artículo científico publicado en 2010

Predominant type 1 CMV-specific memory T-helper response in humans: evidence for gender differences in cytokine secretion

artículo científico publicado en 2004

Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.

artículo científico publicado en 2017

Primary response against cytomegalovirus during antiviral prophylaxis with valganciclovir, in solid organ transplant recipients

artículo científico publicado en 2011

Programmed death-1 expression in liver transplant recipients as a prognostic indicator of cytomegalovirus disease.

artículo científico publicado en 2008

Programmed death-1 receptor and interleukin-10 in liver transplant recipients at high risk for late cytomegalovirus disease

artículo científico publicado en 2010

Rapid Acquisition of Cytomegalovirus-Specific T Cells with a Differentiated Phenotype, in Nonviremic Hematopoietic Stem Transplant Recipients Vaccinated with CMVPepVax

scientific article published on 16 December 2018

Real-time assessment of relapse risk based on the WT1 marker in acute leukemia and myelodysplastic syndrome patients after hematopoietic cell transplantation

artículo científico publicado en 2014

Recombinant modified vaccinia virus Ankara expressing a soluble form of glycoprotein B causes durable immunity and neutralizing antibodies against multiple strains of human cytomegalovirus

artículo científico publicado en 2004

Recombinant modified vaccinia virus ankara (MVA) expressing wild-type human p53 induces specific antitumor CTL expansion.

artículo científico publicado en 2011

Reduced frequencies of polyfunctional CMV-specific T cell responses in infants with congenital CMV infection

artículo científico publicado en 2015

Reduced type 1 and type 2 cytokines in antiviral memory T helper function among women coinfected with HIV and HCV.

artículo científico publicado en 2005

Regulation of growth hormone messenger RNA synthesis by dexamethasone and triiodothyronine. Transcriptional rate and mRNA stability changes in pituitary tumor cells

scientific article published on 01 January 1985

Relative dominance of HLA-B*07 restricted CD8+ T-lymphocyte immune responses to human cytomegalovirus pp65 in persons sharing HLA-A*02 and HLA-B*07 alleles

artículo científico publicado en 2003

Relevance of peptide avidity to the T cell receptor for cytomegalovirus-specific ex vivo CD8 T cell cytotoxicity

artículo científico publicado en 2003

Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors

artículo científico publicado en 2015

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

scientific article published on 01 March 2019

Simultaneous reconstitution of multiple cytomegalovirus-specific CD8+ cell populations with divergent functionality in hematopoietic stem-cell transplant recipients.

artículo científico publicado en 2005

Site-directed mutation in a conserved kinase domain of human cytomegalovirus-pp65 with preservation of cytotoxic T lymphocyte targeting.

artículo científico publicado en 2001

Status of Cytomegalovirus Prevention and Treatment in 2000.

artículo científico publicado en 2000

Survivin the battle against immunosuppression.

artículo científico publicado en 2012

Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth

artículo científico publicado en 2012

TLR9 signaling in the tumor microenvironment initiates cancer recurrence after radiotherapy

artículo científico publicado en 2013

The effect of single and combined activating killer immunoglobulin-like receptor genotypes on cytomegalovirus infection and immunity after hematopoietic cell transplantation

artículo científico publicado en 2009

The immune response to human CMV

artículo científico publicado en 2012

The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains.

artículo científico publicado en 2016

The use of transgenic mice to generate high affinity p53 specific cytolytic T cells.

artículo científico publicado en 1997

Tumor growth control with IDO-silencing Salmonella--reply

artículo científico publicado en 2013

Two distinct pathways of immuno-modulation improve potency of p53 immunization in rejecting established tumors.

artículo científico publicado en 2004

Unusual organization and diversity of T-cell receptor alpha-chain genes.

artículo científico publicado en 1985

Vaccine properties of a novel marker gene-free recombinant modified vaccinia Ankara expressing immunodominant CMV antigens pp65 and IE1.

artículo científico publicado en 2006

Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection

artículo científico publicado en 2015

Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques.

artículo científico publicado en 2010

Viraemia, immunogenicity, and survival outcomes of cytomegalovirus chimeric epitope vaccine supplemented with PF03512676 (CMVPepVax) in allogeneic haemopoietic stem-cell transplantation: randomised phase 1b trial

artículo científico publicado en 2015

p53-reactive T cells are associated with clinical benefit in patients with platinum-resistant epithelial ovarian cancer after treatment with a p53 vaccine and gemcitabine chemotherapy

artículo científico publicado en 2018

p53MVA therapy in patients with refractory gastrointestinal malignancies elevates p53-specific CD8+ T-cell responses

artículo científico publicado en 2014