Lista de obras - Franca Fraternali - Dominio Público Uruguay

A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex-An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface

scientific article published on 14 December 2020

A case-by-case evolutionary analysis of four imprinted retrogenes ⬇️

artículo científico publicado en 2011

A computational exploration of the interactions of the green tea polyphenol (-)-Epigallocatechin 3-Gallate with cardiac muscle troponin C

artículo científico publicado en 2013

A conformational study in solution of pro-somatostatin fragments by NMR and computational methods

artículo científico publicado en 1998

A multiscale approach to the elastic moduli of biomembrane networks.

artículo científico publicado en 2012

A refined, efficient mean solvation force model that includes the interior volume contribution

artículo científico publicado en 2011

A solvable model of the genesis of amino-acid sequences via coupled dynamics of folding and slow-genetic variation

A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse

artículo científico publicado en 2011

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

artículo científico publicado en 2018

AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking

artículo científico publicado en 2014

An Efficient Mean Solvation Force Model for Use in Molecular Dynamics Simulations of Proteins in Aqueous Solution

article

An engineered photoswitchable mammalian pyruvate kinase

artículo científico publicado en 2017

An immunoglobulin-like fold in a major plant allergen: the solution structure of Phl p 2 from timothy grass pollen

artículo científico publicado en 1999

Anatomy of protein disorder, flexibility and disease-related mutations

artículo científico publicado en 2015

Assembly of Influenza Hemagglutinin Fusion Peptides in a Phospholipid Bilayer by Coarse-grained Computer Simulations

artículo científico publicado en 2015

B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease ⬇️

artículo científico publicado el 10 de abril de 2012

BCR-ABL residues interacting with ponatinib are critical to preserve the tumorigenic potential of the oncoprotein

artículo científico publicado en 2013

BRepertoire: a user-friendly web server for analysing antibody repertoire data

artículo científico publicado en 2018

Bidirectional barbed suture in laparoscopic myomectomy: clinical features

artículo científico publicado en 2013

Biomechanical features of bidirectional-barbed suture: a randomized laboratory analysis

artículo científico publicado en 2014

Bridging topological and functional information in protein interaction networks by short loops profiling

artículo científico publicado en 2015

Calcium regulates scallop muscle by changing myosin flexibility

scientific article published on 11 January 2006

Conformation and dynamics of a rhodamine probe attached at two sites on a protein: implications for molecular structure determination in situ

artículo científico publicado en 2008

Conformational analysis of dolastatin 10: an NMR and theoretical approach

artículo científico publicado en 1995

Conformational preferences and self-association modes of two diastereomeric statine derivatives

artículo científico publicado en 1987

Correction: B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease.

artículo científico publicado en 2012

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

artículo científico publicado en 2020

Decrypting Prion Protein Conversion into a β-Rich Conformer by Molecular Dynamics

artículo científico publicado en 2013

Design and application of implicit solvent models in biomolecular simulations

artículo científico publicado en 2014

Design and solution structure of a partially rigid opioid antagonist lacking the basic center--models of antagonism

artículo científico publicado en 1997

Detection of allosteric signal transmission by information-theoretic analysis of protein dynamics

artículo científico publicado en 2011

Development of new laccases by directed evolution: functional and computational analyses

artículo científico publicado en 2008

Dynamic domain threading

artículo científico publicado en 2006

Effects of pathological mutations on the stability of a conserved amino acid triad in retinoschisin

artículo científico publicado en 2003

Emerging role of the ubiquitin-proteasome system as drug targets

artículo científico

Engineering Chirally Blind Protein Pseudocapsids into Antibacterial Persisters

scientific article published on 05 December 2019

Exploring protein interiors: the role of a buried histidine in the KH module fold

artículo científico publicado en 1999

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

artículo científico publicado en 2019

GSATools: analysis of allosteric communication and functional local motions using a structural alphabet

artículo científico publicado en 2013

Genetic variants and protein-protein interactions: a multidimensional network-centric view

artículo científico publicado en 2018

Highly nonlinear pulse splitting and recombination in a two-dimensional granular network

artículo científico publicado en 2010

Highly nonlinear solitary wave propagation in Y-shaped granular crystals with variable branch angles.

artículo científico publicado en 2012

Homology-Based Modeling of Universal Stress Protein from Listeria innocua Up-Regulated under Acid Stress Conditions

scientific article published on 20 December 2016

How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology

artículo científico publicado en 2011

Hydrogen-bonding propensities of sphingomyelin in solution and in a bilayer assembly: a molecular dynamics study

artículo científico publicado en 2003

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors

Implicit Solvation Parameters Derived from Explicit Water Forces in Large-Scale Molecular Dynamics Simulations

artículo científico publicado en 2012

In silico identification of rescue sites by double force scanning

artículo científico publicado en 2017

In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation

artículo científico publicado en 2010

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface

artículo científico publicado en 2018

Interaction of malaria parasite-inhibitory antibodies with the merozoite surface protein MSP1(19) by computational docking

artículo científico publicado en 2007

Interactions of the C2 domain of human factor V with a model membrane

artículo científico publicado en 2006

Investigating Ebola virus pathogenicity using molecular dynamics

artículo científico publicado en 2017

Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites

artículo científico publicado en 2009

Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins

artículo científico publicado en 2013

Lipid Head Group Parameterization for GROMOS 54A8: A Consistent Approach with Protein Force Field Description

scientific article published on 09 September 2019

Mapping disease-related missense mutations in the immunoglobulin-like fold domain of lamin A/C reveals novel genotype-phenotype associations for laminopathies

artículo científico publicado en 2013

Mapping the active site of factor Xa by selective inhibitors: An NMR and MD study ⬇️

artículo científico publicado el 15 de febrero de 1998

MinSet: a general approach to derive maximally representative database subsets by using fragment dictionaries and its application to the SCOP database

artículo científico publicado en 2007

Mode of binding of camptothecins to double helix oligonucleotides

artículo científico publicado en 2004

Modeling and in situ identification of material parameters for layered structures based on carbon nanotube arrays

article

Modularity and homology: modelling of the titin type I modules and their interfaces

article

Modularity and homology: modelling of the type II module family from titin

article

Molecular determinants of peculiar properties of a Pleurotus ostreatus laccase: Analysis by site-directed mutagenesis

article

Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.

artículo científico publicado en 2008

Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights

article

Mutation of the RAD51C gene in a Fanconi anemia-like disorder

artículo científico publicado en 2010

Neurologically active plant compounds and peptide hormones: a chirality connection

article

Novel RNA-binding motif: the KH module

artículo científico publicado en 1999

On the estimation of the curvatures and bending rigidity of membrane networks via a local maximum-entropy approach

POPS: A fast algorithm for solvent accessible surface areas at atomic and residue level

artículo científico publicado en 2003

POPSCOMP: an automated interaction analysis of biomolecular complexes

artículo científico publicado en 2005

Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases

artículo científico publicado en 2019

Parameter optimized surfaces (POPS): analysis of key interactions and conformational changes in the ribosome

artículo científico publicado en 2002

PinSnps: structural and functional analysis of SNPs in the context of protein interaction networks

artículo científico publicado en 2016

Plasticity and conformational equilibria of influenza fusion peptides in model lipid bilayers

artículo científico publicado en 2014

Plasticity of influenza haemagglutinin fusion peptides and their interaction with lipid bilayers

artículo científico publicado en 2004

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

artículo científico publicado en 2015

Probing the early stages of prion protein (PrP) aggregation with atomistic molecular dynamics simulations

scholarly article by Francesca Collu et al published 2018 in Chemical Communications

Promiscuous antibodies characterised by their physico-chemical properties: From sequence to structure and back

artículo científico publicado en 2016

Protein networks reveal detection bias and species consistency when analysed by information-theoretic methods

artículo científico publicado en 2010

Protein-protein interaction networks studies and importance of 3D structure knowledge

artículo científico

Protein-water interactions in MD simulations: POPS/POPSCOMP solvent accessibility analysis, solvation forces and hydration sites

artículo científico publicado en 2012

RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1

artículo científico publicado en 2009

Rationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulations

artículo científico publicado en 2010

Reorganization in apo- and holo-beta-lactoglobulin upon protonation of Glu89: molecular dynamics and pKa calculations

artículo científico publicado en 2004

Restrained and unrestrained molecular dynamics simulations in the NVT ensemble of alamethicin

article

RhoBTB1 interacts with ROCKs and inhibits invasion

scientific article published on 13 September 2019

SARS-CoV-2 spike protein predicted to form stable complexes with host receptor protein orthologues from mammals

artículo científico publicado en 2020

Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks

artículo científico publicado en 2021

Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions

artículo científico publicado en 2016

Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways

artículo científico publicado en 2021

Specialized Dynamical Properties of Promiscuous Residues Revealed by Simulated Conformational Ensembles

artículo científico publicado en 2013

Stability and Cations Coordination of DNA and RNA 14-Mer G-Quadruplexes: A Multiscale Computational Approach

Structural Properties of Green Tea Catechins

artículo científico publicado en 2015

Structural features of the regulatory ACT domain of phenylalanine hydroxylase

artículo científico publicado en 2013

Structural insight into the h TERT intron 6 sequence d(GGGGTGAAAGGGG) from 1H-NMR study

scholarly article by Ada Virno et al published 26 November 2007 in Nucleosides, Nucleotides & Nucleic Acids

Structural versatility of peptides containing C alpha, alpha-dialkylated glycines. An X-ray diffraction study of six 1-aminocyclopropane-1-carboxylic acid rich peptides

artículo científico publicado en 1989

Structural versatility of peptides containing Cα,α-dialkylated glycines: conformational energy computations, i.r. absorption and 1H n.m.r. analysis of 1-aminocyclopropane-1-carboxylic acid homopeptides

article

Structure and Dynamics of Nanoconfined Water Between Surfactant Monolayers

artículo científico publicado en 2019

Structure and stability insights into tumour suppressor p53 evolutionary related proteins

artículo científico publicado en 2013

Surface Accessibility and Dynamics of Macromolecular Assemblies Probed by Covalent Labeling Mass Spectrometry and Integrative Modeling

artículo científico publicado en 2017

Symmetry-breaking transitions in the early steps of protein self-assembly

artículo científico publicado en 2020

TITINdb-a computational tool to assess titin's role as a disease gene

artículo científico publicado en 2017

Tailored graph ensembles as proxies or null models for real networks I: tools for quantifying structure

artículo científico publicado en 2009

The oligomerization properties of prion protein are restricted to the H2H3 domain

The p73 DNA binding domain displays enhanced stability relative to its homologue, the tumor suppressor p53, and exhibits cooperative DNA binding

artículo científico publicado en 2008

The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome

artículo científico publicado en 1997

Thermal unfolding simulations of apo-calmodulin using leap-dynamics

artículo científico publicado en 2003

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

artículo científico publicado en 2019

Toward the understanding of MNEI sweetness from hydration map surfaces

artículo científico publicado en 2006

Towards the identification of the allosteric Phe-binding site in phenylalanine hydroxylase

artículo científico publicado en 2015

Transitional B Cells in Early Human B Cell Development - Time to Revisit the Paradigm?

scientific article published on 02 December 2016

Understanding the structural details of APOBEC3-DNA interactions using graph-based representations

artículo científico publicado en 2020

Urea–Water Solvation Forces on Prion Structures ⬇️

artículo científico publicado el 14 de agosto de 2012

Water molecules as structural determinants among prions of low sequence identity

artículo científico publicado en 2006

When a module is not a domain: the case of the REJ module and the redefinition of the architecture of polycystin-1.

artículo científico publicado en 2011

Lista de obras de Franca Fraternali

A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex-An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface

A case-by-case evolutionary analysis of four imprinted retrogenes ⬇️

A computational exploration of the interactions of the green tea polyphenol (-)-Epigallocatechin 3-Gallate with cardiac muscle troponin C

A conformational study in solution of pro-somatostatin fragments by NMR and computational methods

A multiscale approach to the elastic moduli of biomembrane networks.

A refined, efficient mean solvation force model that includes the interior volume contribution

A solvable model of the genesis of amino-acid sequences via coupled dynamics of folding and slow-genetic variation

A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking

An Efficient Mean Solvation Force Model for Use in Molecular Dynamics Simulations of Proteins in Aqueous Solution

An engineered photoswitchable mammalian pyruvate kinase

An immunoglobulin-like fold in a major plant allergen: the solution structure of Phl p 2 from timothy grass pollen

Anatomy of protein disorder, flexibility and disease-related mutations

Assembly of Influenza Hemagglutinin Fusion Peptides in a Phospholipid Bilayer by Coarse-grained Computer Simulations

B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease ⬇️

BCR-ABL residues interacting with ponatinib are critical to preserve the tumorigenic potential of the oncoprotein

BRepertoire: a user-friendly web server for analysing antibody repertoire data

Bidirectional barbed suture in laparoscopic myomectomy: clinical features

Biomechanical features of bidirectional-barbed suture: a randomized laboratory analysis

Bridging topological and functional information in protein interaction networks by short loops profiling

Calcium regulates scallop muscle by changing myosin flexibility

Conformation and dynamics of a rhodamine probe attached at two sites on a protein: implications for molecular structure determination in situ

Conformational analysis of dolastatin 10: an NMR and theoretical approach

Conformational preferences and self-association modes of two diastereomeric statine derivatives

Correction: B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease.

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells

Decrypting Prion Protein Conversion into a β-Rich Conformer by Molecular Dynamics

Design and application of implicit solvent models in biomolecular simulations

Design and solution structure of a partially rigid opioid antagonist lacking the basic center--models of antagonism

Detection of allosteric signal transmission by information-theoretic analysis of protein dynamics

Development of new laccases by directed evolution: functional and computational analyses

Dynamic domain threading

Effects of pathological mutations on the stability of a conserved amino acid triad in retinoschisin

Emerging role of the ubiquitin-proteasome system as drug targets

Engineering Chirally Blind Protein Pseudocapsids into Antibacterial Persisters

Exploring protein interiors: the role of a buried histidine in the KH module fold

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

GSATools: analysis of allosteric communication and functional local motions using a structural alphabet

Genetic variants and protein-protein interactions: a multidimensional network-centric view

Highly nonlinear pulse splitting and recombination in a two-dimensional granular network

Highly nonlinear solitary wave propagation in Y-shaped granular crystals with variable branch angles.

Homology-Based Modeling of Universal Stress Protein from Listeria innocua Up-Regulated under Acid Stress Conditions

How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology

Hydrogen-bonding propensities of sphingomyelin in solution and in a bilayer assembly: a molecular dynamics study

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors

Implicit Solvation Parameters Derived from Explicit Water Forces in Large-Scale Molecular Dynamics Simulations

In silico identification of rescue sites by double force scanning

In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface

Interaction of malaria parasite-inhibitory antibodies with the merozoite surface protein MSP1(19) by computational docking

Interactions of the C2 domain of human factor V with a model membrane

Investigating Ebola virus pathogenicity using molecular dynamics

Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites

Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins

Lipid Head Group Parameterization for GROMOS 54A8: A Consistent Approach with Protein Force Field Description

Mapping disease-related missense mutations in the immunoglobulin-like fold domain of lamin A/C reveals novel genotype-phenotype associations for laminopathies

Mapping the active site of factor Xa by selective inhibitors: An NMR and MD study ⬇️

MinSet: a general approach to derive maximally representative database subsets by using fragment dictionaries and its application to the SCOP database

Mode of binding of camptothecins to double helix oligonucleotides

Modeling and in situ identification of material parameters for layered structures based on carbon nanotube arrays

Modularity and homology: modelling of the titin type I modules and their interfaces

Modularity and homology: modelling of the type II module family from titin

Molecular determinants of peculiar properties of a Pleurotus ostreatus laccase: Analysis by site-directed mutagenesis

Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax.

Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights

Mutation of the RAD51C gene in a Fanconi anemia-like disorder

Neurologically active plant compounds and peptide hormones: a chirality connection

Novel RNA-binding motif: the KH module

On the estimation of the curvatures and bending rigidity of membrane networks via a local maximum-entropy approach

POPS: A fast algorithm for solvent accessible surface areas at atomic and residue level

POPSCOMP: an automated interaction analysis of biomolecular complexes

Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases

Parameter optimized surfaces (POPS): analysis of key interactions and conformational changes in the ribosome

PinSnps: structural and functional analysis of SNPs in the context of protein interaction networks

Plasticity and conformational equilibria of influenza fusion peptides in model lipid bilayers

Plasticity of influenza haemagglutinin fusion peptides and their interaction with lipid bilayers

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

Probing the early stages of prion protein (PrP) aggregation with atomistic molecular dynamics simulations