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Lista de obras de Volker M. Arlt

3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.

artículo científico publicado en 2009

3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence.

artículo científico publicado en 2005

3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung.

artículo científico publicado en 2009

3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.

artículo científico publicado en 2004

A Compendium of Mutational Signatures of Environmental Agents

artículo científico publicado en 2019

A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches

artículo científico publicado en 2015

ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues.

artículo científico publicado en 2012

AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines.

artículo científico

Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes.

artículo científico publicado en 2012

Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells

artículo científico publicado en 2004

Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.

artículo científico publicado en 2016

Altered gene expression profiles in the lungs of benzo[a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation.

artículo científico publicado en 2017

Antagonistic Interactions between Benzo[a]pyrene and Fullerene (C60) in Toxicological Response of Marine Mussels

scientific article published on 08 July 2019

Application of hepatic cytochrome b/P450 reductase null (HBRN) mice to study the role of cytochrome b in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

scientific article published on 25 January 2019

Aristolochic acid (AA)-DNA adduct as marker of AA exposure and risk factor for AA nephropathy-associated cancer

artículo científico publicado en 2004

Aristolochic acid as a probable human cancer hazard in herbal remedies: a review.

artículo científico publicado en 2002

Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells

artículo científico publicado en 2001

Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

artículo científico publicado en 2007

Aristolochic acid nephropathy and the peritoneum: Functional, structural, and molecular studies

artículo científico publicado en 2003

Aristolochic acid nephropathy in a Chinese patient: time to abandon the term "Chinese herbs nephropathy"?

artículo científico publicado en 2001

Aristolochic acid-induced carcinogenesis examined by ACB-PCR quantification of H-Ras and K-Ras mutant fraction.

artículo científico publicado en 2011

Assessing the impact of Benzo[a]pyrene on Marine Mussels: Application of a novel targeted low density microarray complementing classical biomarker responses

artículo científico publicado en 2017

Bacillus Calmette-Guerin therapy in non-muscle-invasive bladder carcinoma after renal transplantation for end-stage aristolochic acid nephropathy.

artículo científico publicado en 2014

Balkan endemic nephropathy: an update on its aetiology

artículo científico publicado en 2016

Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene

artículo científico publicado en 2017

Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice

artículo científico publicado en 2014

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

artículo científico publicado en 2006

Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.

artículo científico publicado en 2011

Bulky DNA adducts, microRNA profiles, and lipid biomarkers in Norwegian tunnel finishing workers occupationally exposed to diesel exhaust

artículo científico publicado en 2018

C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2

artículo científico publicado en 2013

Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.

artículo científico publicado en 2014

Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved.

artículo científico publicado en 2013

Co-exposure to polystyrene plastic beads and polycyclic aromatic hydrocarbon contaminants in fish gill (RTgill-W1) and intestinal (RTgutGC) epithelial cells derived from rainbow trout (Oncorhynchus mykiss)

scientific article published on 22 February 2019

Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action

artículo científico publicado en 2016

Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems

artículo científico publicado en 2017

Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

artículo científico publicado en 2014

Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches

artículo científico publicado en 2017

Constitutive expression of bioactivating enzymes in normal human prostate suggests a capability to activate pro-carcinogens to DNA-damaging metabolites.

artículo científico publicado en 2010

Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice

artículo científico publicado en 2018

Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions.

artículo científico publicado en 2014

Cytochrome b5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine.

artículo científico publicado en 2017

Cytotoxic and genotoxic responses of the RTgill-W1 fish cells in combination with the yeast oestrogen screen to determine the sediment quality of Lagos lagoon, Nigeria.

artículo científico publicado en 2015

DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer

artículo científico publicado en 2017

DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver.

artículo científico publicado en 2006

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone after intratracheal instillation in rats

artículo científico publicado en 2005

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone in V79 cells expressing human cytochrome P450 enzymes

artículo científico publicado en 2003

DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats

artículo científico publicado en 2003

DNA adduct formation in human hepatoma cells treated with 3-nitrobenzanthrone: analysis by the (32)P-postlabeling method

artículo científico publicado en 2007

DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse

artículo científico publicado en 2004

DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy

artículo científico publicado en 2004

DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis.

artículo científico publicado en 2011

Detection and quantitation of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adducts in DNA using online column-switching liquid chromatography tandem mass spectrometry.

artículo científico publicado en 2010

Detection of Herba Aristolochia Mollissemae in a patient with unexplained nephropathy

artículo científico publicado en 2005

Dicoumarol inhibits rat NAD(P)H:quinone oxidoreductase in vitro and induces its expression in vivo

artículo científico publicado en 2014

Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells.

artículo científico publicado en 2007

Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells

artículo científico publicado en 2009

Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers.

artículo científico publicado en 2018

ECNIS-sponsored workshop on biomarkers of exposure and cancer risk: DNA damage and DNA adduct detection and 6th GUM-32P-postlabelling workshop, German Cancer Research Center, Heidelberg, Germany, 29-30 September 2006.

artículo científico publicado en 2006

Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies

artículo científico publicado en 2005

Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null mice.

artículo científico publicado en 2011

Effects of dexfenfluramine on aristolochic acid nephrotoxicity in a rat model for Chinese-herb nephropathy

artículo científico publicado en 2003

Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects.

artículo científico publicado en 2006

Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2 ⬇️

artículo científico publicado el 1 de septiembre de 2008

Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells

scientific article published on 23 March 2019

Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer.

artículo científico

Erratum to "Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53" [Toxicol. Appl. Pharmacol. 232(1) (2008) 86-98].

artículo científico publicado en 2018

Evaluation of the cytotoxicity and genotoxicity of aristolochic acid I - a component of Aristolochiaceae plant extracts used in homeopathy

artículo científico publicado en 2013

Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania.

artículo científico publicado en 2012

Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy

article

Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling.

artículo científico publicado en 2012

Formation and persistence of DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in target and non-target organs after intratracheal instillation in rats

artículo científico publicado en 2006

Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice

artículo científico

Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53.

artículo científico publicado en 2008

Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in MutaMouse and lung epithelial cells derived from MutaMouse

artículo científico publicado en 2008

Genotoxicity of fine and coarse fraction ambient particulate matter in immortalised normal (TT1) and cancer-derived (A549) alveolar epithelial cells

artículo científico publicado en 2018

Hepatic DNA damage in harbour porpoises (Phocoena phocoena) stranded along the English and Welsh coastlines

artículo científico publicado en 2018

Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene

artículo científico publicado en 2013

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.

artículo científico publicado en 2003

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation

scientific article published on 10 July 2019

Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine

artículo científico publicado en 2006

Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53.

artículo científico publicado en 2007

Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.

artículo científico publicado en 2016

Impact of p53 function on the sulfotransferase-mediated bioactivation of the alkylated polycyclic aromatic hydrocarbon 1-hydroxymethylpyrene in vitro

artículo científico publicado en 2019

Induced expression of microsomal cytochrome b 5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I).

artículo científico publicado en 2016

Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats

scientific article published on 15 December 2010

Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo

artículo científico publicado en 2016

Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene

artículo científico publicado en 2016

Invasive urothelial carcinoma after exposure to Chinese herbal medicine containing aristolochic acid may occur without severe renal failure.

artículo científico publicado en 2003

Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer?

artículo científico publicado en 2002

Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid.

artículo científico publicado en 2013

Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model.

scientific article published on June 2010

Mechanisms linked to differences in the mutagenic potential of 1,3-dinitropyrene and 1,8-dinitropyrene

artículo científico publicado en 2014

Mechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approaches

artículo científico publicado en 2014

Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone

artículo científico publicado en 2010

Merging nano-genotoxicology with eco-genotoxicology: An integrated approach to determine interactive genotoxic and sub-lethal toxic effects of C60 fullerenes and fluoranthene in marine mussels, Mytilus sp

article

Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.

artículo científico publicado en 2008

Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.

artículo científico publicado en 2007

Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts

artículo científico publicado en 2012

Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5.

artículo científico publicado en 2014

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

artículo científico publicado en 2009

Mutagenic potential of nitrenium ions of nitrobenzanthrones: correlation between theory and experiment

artículo científico publicado en 2008

Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue® rats

artículo científico publicado en 2012

Mutagenicity and DNA adduct formation by the urban air pollutant 2-nitrobenzanthrone

artículo científico publicado en 2007

Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts

artículo científico publicado en 2020

NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I.

artículo científico publicado en 2012

NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1.

artículo científico publicado en 2016

Nutlin-3a selects for cells harbouring TP53 mutations

artículo científico publicado en 2016

Oral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations.

artículo científico publicado en 2016

Organ specificity of DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen in the rat: implications for understanding the mechanism(s) of tamoxifen carcinogenicity and for human risk assessment

artículo científico publicado en 2005

Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy

artículo científico publicado en 2012

Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.

artículo científico publicado en 2013

Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

artículo científico publicado en 2015

Quantification of 3-nitrobenzanthrone-DNA adducts using online column-switching HPLC-electrospray tandem mass spectrometry

artículo científico publicado en 2009

Quantitative relationships between lacZ mutant frequency and DNA adduct frequency in Muta™Mouse tissues and cultured cells exposed to 3-nitrobenzanthrone

artículo científico publicado en 2017

Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone.

artículo científico publicado en 2008

Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone

artículo científico publicado en 2018

Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.

artículo científico publicado en 2011

Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.

artículo científico publicado en 2011

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse.

artículo científico publicado en 2007

Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and DNA adducts in Muta™ Mouse

artículo científico publicado en 2011

Subchronic oral exposure to benzo(a)pyrene leads to distinct transcriptomic changes in the lungs that are related to carcinogenesis

artículo científico publicado en 2012

Synthesis, characterization, and 32p-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthrone

artículo científico publicado en 2005

THE ENVIRONMENTAL POLLUTANT AND CARCINOGEN 3-NITROBENZANTHRONE AND ITS HUMAN METABOLITE 3-AMINOBENZANTHRONE ARE POTENT INDUCERS OF RAT HEPATIC CYTOCHROMES P450 1A1 AND -1A2 AND NAD(P)H:QUINONE OXIDOREDUCTASE

artículo científico publicado en 2006

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

artículo científico publicado en 2016

TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

artículo científico publicado en 2009

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

artículo científico publicado en 2015

The 32P-postlabeling assay for DNA adducts

scientific article published on 01 January 2007

The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytes.

artículo científico publicado en 2013

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

artículo científico publicado en 2018

The Impact of p53 on Aristolochic Acid I-Induced Gene Expression In Vivo ⬇️

scientific article published on 06 December 2019

The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes.

artículo científico publicado en 2014

The application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegans

artículo científico publicado en 2016

The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats--a comparative study.

artículo científico publicado en 2014

The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice

The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy.

artículo científico publicado en 2015

The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity

artículo científico publicado en 2008

The genome as a record of environmental exposure

artículo científico publicado en 2015

The genotoxic air pollutant 3-nitrobenzanthrone and its reactive metabolite N-hydroxy-3-aminobenzanthrone lack initiating and complete carcinogenic activity in NMRI mouse skin.

artículo científico publicado en 2009

The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases

scientific article published on 02 March 2011

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.

artículo científico publicado en 2016

The impact of p53 function on the metabolic activation of the carcinogenic air pollutant 3-nitrobenzanthrone and its metabolites 3-aminobenzanthrone and N-hydroxy-3-aminobenzanthrone in human cells

scientific article published on 01 October 2018

The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro

scientific article published on 10 October 2019

The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats

scientific article published on 05 March 2014

The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats

artículo científico publicado en 2014

The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat.

artículo científico publicado en 2013

Theoretical investigations on the formation of nitrobenzanthrone-DNA Adducts

artículo científico publicado en 2011

Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.

artículo científico publicado en 2006

Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay

artículo científico publicado en 2015

Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse.

artículo científico publicado en 2015

Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene.

artículo científico publicado en 2016

Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro

artículo científico publicado en 2019

UKEMS/Dutch EMS-sponsored workshop on biomarkers of exposure and oxidative DNA damage & 7th GUM-32P-postlabelling workshop, University of Münster, Münster, Germany, 28-29 March 2011.

artículo científico publicado en 2011

Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)

artículo científico publicado en 2000

Urothelial malignant disease and Chinese herbal nephropathy

artículo científico publicado en 2001

Whole body exposure of mice to secondhand smoke induces dose-dependent and persistent promutagenic DNA adducts in the lung.

artículo científico publicado en 2011

³²P-postlabeling analysis of DNA adducts

artículo científico publicado en 2013

³²P-postlabeling analysis of DNA adducts.

artículo científico publicado en 2014

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