Lista de obras - Craig A. Hutton - Dominio Público Uruguay

1,3-Phenylene bis(ketoacid) derivatives as inhibitors of Escherichia coli dihydrodipicolinate synthase

artículo científico publicado en 2012

A general method for interconversion of boronic acid protecting groups: trifluoroborates as common intermediates.

artículo científico publicado en 2015

A new method for peptide synthesis in the N→C direction: amide assembly through silver-promoted reaction of thioamides

artículo científico publicado en 2014

A new robust kinetic assay for DAP epimerase activity

artículo científico publicado en 2013

Automated preparation of 2-[18 F]fluoropropionate labeled peptides using a flexible, multi-stage synthesis platform (iPHASE Flexlab).

artículo científico publicado en 2017

Automated preparation of clinical grade [68Ga]Ga-DOTA-CP04, a cholecystokinin-2 receptor agonist, using iPHASE MultiSyn synthesis platform

scientific article published on 23 August 2019

Beyond RGD; nanoclusters of syndecan- and integrin-binding ligands synergistically enhance cell/material interactions

artículo científico publicado en 2018

Biochemical characterization of a recombinant thermoalkalophilic lipase and assessment of its substrate enantioselectivity

Biomaterials functionalized with nanoclusters of integrin- and syndecan-binding ligands improve cell adhesion and mechanosensing under shear flow conditions

artículo científico publicado en 2020

Blood-borne amyloid-beta dimer correlates with clinical markers of Alzheimer's disease

artículo científico publicado en 2010

Celogentin mimetics as inhibitors of tubulin polymerization

scientific article published on 17 December 2019

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

artículo científico publicado en 2009

Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry

artículo científico publicado en 2017

Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase.

artículo científico publicado en 2007

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

artículo científico publicado en 2008

Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity.

artículo científico publicado en 2017

Copper-free palladium-catalyzed Sonogashira and Hiyama cross-couplings using aryl imidazol-1-ylsulfonates

Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli

artículo científico publicado en 2009

Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates

artículo científico publicado en 2005

Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis

artículo científico publicado en 2013

Effects of PPAR gamma ligands on TGF-beta1-induced epithelial-mesenchymal transition in alveolar epithelial cells.

artículo científico publicado en 2010

Enantioselective preparation of a stable boronate complex stereogenic only at boron

artículo científico publicado en 2008

Establishing Signature Fragments for Identification and Sequencing of Dityrosine Cross-Linked Peptides Using Ultraviolet Photodissociation Mass Spectrometry

artículo científico publicado en 2019

Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate

artículo científico publicado en 2009

Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive.

artículo científico publicado en 2005

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

artículo científico publicado en 2017

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

scientific journal article

Inhibiting protein-protein interactions as an emerging paradigm for drug discovery.

artículo científico publicado en 2007

Inhibition of lysine biosynthesis: an evolving antibiotic strategy

artículo científico publicado en 2007

Inhibitors of lysine biosynthesis as antibacterial agents

artículo científico publicado en 2003

Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues

artículo científico publicado en 2008

LC-MS and NMR characterization of the purple chromophore formed in the o-aminobenzaldehyde assay of dihydrodipicolinate synthase

artículo científico publicado en 2010

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.

artículo científico publicado en 2016

Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity

artículo científico publicado en 2013

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples.

artículo científico publicado en 2013

One-step radiosynthesis of 4-nitrophenyl 2-[(18) F]fluoropropionate ([(18) F]NFP); improved preparation of radiolabeled peptides for PET imaging

artículo científico publicado en 2013

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

artículo científico publicado en 2017

Potentially Macrocyclic Peptidyl Boronic Acids as Chymotrypsin Inhibitors

artículo científico publicado en 1997

Preparation of Cyclic Peptide Alkaloids Containing Functionalized Tryptophan Residues

artículo científico publicado en 2007

Preparation of beta-nitroalanine using the Easton three-component coupling method

scientific article published on 20 March 2006

Preparation of diazabicyclo[4.3.0]nonene-based peptidomimetics

artículo científico publicado en 2007

Preparation of the Central Tryptophan Moiety (I) of the Celogentin/Moroidin Family of Antimitotic Cyclic Peptides

Preparation of the Central Tryptophan Moiety of the Celogentin/Moroidin Family of Anti-Mitotic Cyclic Peptides

Rapid, Traceless, AgI -Promoted Macrocyclization of Peptides Possessing an N-Terminal Thioamide

artículo científico publicado en 2019

Recent developments in radiolabelled peptides for PET imaging of cancer

article

Role of 2-oxo and 2-thioxo modifications on the fragmentation reactions of the histidine radical cation

scientific article published on 01 January 2011

Role of 2-oxo and 2-thioxo modifications on the proton affinity of histidine and fragmentation reactions of protonated histidine.

artículo científico publicado en 2010

Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid β peptide

article

Structure of olefin-imidacloprid and gas-phase fragmentation chemistry of its protonated form.

artículo científico publicado en 2016

Structure-Activity Relationships of cyclo(l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct

artículo científico publicado en 2019

Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax

artículo científico publicado en 2010

Sulfonation of Tyrosine as a Method To Improve Biodistribution of Peptide-Based Radiotracers: Novel 18F-Labeled Cyclic RGD Analogues

artículo científico publicado en 2017

Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives.

artículo científico publicado en 2018

Synthesis of Peptides by Silver-Promoted Coupling of Carboxylates and Thioamides: Mechanistic Insight from Computational Studies.

artículo científico publicado en 2016

Synthesis of beta-hydroxy-beta-(fluoronitrophenyl)alanines: vital components in the assembly of biologically active cyclic peptides

artículo científico publicado en 1999

Synthesis of cyclic peptide hemicryptophanes: enantioselective recognition of a chiral zwitterionic guest

scientific article published on 01 October 2013

Synthesis of the C-Terminal Macrocycle of Asperipin-2a

scientific article published on 06 March 2019

Synthesis of the beta-hydroxydopa-gamma-hydroxy-delta-sulfinylnorvaline component of ustiloxins A and B.

artículo científico publicado en 2005

Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine.

artículo científico publicado en 2005

Synthesis of β,γ-dihydroxyhomotyrosines by a tandem Petasis-asymmetric dihydroxylation approach

artículo científico publicado en 2011

Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers

article

Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome

artículo científico publicado en 2018

The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product ⬇️

artículo científico publicado el 4 de junio de 2012

The enantioselective synthesis of APTO and AETD: polyhydroxylated beta-amino acid constituents of the microsclerodermin cyclic peptides

artículo científico publicado en 2007

Total Synthesis of Seongsanamide B

artículo científico publicado en 2020

Total Synthesis of Ustiloxin D Utilizing an Ammonia-Ugi Reaction

artículo científico publicado en 2015

Total Synthesis of the Putative Structure of Asperipin-2a and Stereochemical Reassignment

scientific article published on 22 September 2020

Total synthesis of (-)-reveromycin B

artículo científico publicado en 2000

Total synthesis of mycocyclosin

scientific article published on 20 April 2012

Total synthesis of the epidermal growth factor inhibitor (-)-reveromycin B.

artículo científico publicado en 2001

Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate.

artículo científico publicado en 2005

Unimolecular reactivity of organotrifluoroborate anions, RBF3- , and their alkali metal cluster ions, M(RBF3 )2- (M = Na, K; R = CH3 , CH3 CH2 , CH3 (CH2 )3 , CH3 (CH2 )5 , c-C3 H5 , C6 H5 , C6 H5 CH2 , CH2 CHCH2 , CH2 CH, C6 H5 CO)

artículo científico publicado en 2018

Lista de obras de Craig A. Hutton

1,3-Phenylene bis(ketoacid) derivatives as inhibitors of Escherichia coli dihydrodipicolinate synthase

A general method for interconversion of boronic acid protecting groups: trifluoroborates as common intermediates.

A new method for peptide synthesis in the N→C direction: amide assembly through silver-promoted reaction of thioamides

A new robust kinetic assay for DAP epimerase activity

Automated preparation of 2-[18 F]fluoropropionate labeled peptides using a flexible, multi-stage synthesis platform (iPHASE Flexlab).

Automated preparation of clinical grade [68Ga]Ga-DOTA-CP04, a cholecystokinin-2 receptor agonist, using iPHASE MultiSyn synthesis platform

Beyond RGD; nanoclusters of syndecan- and integrin-binding ligands synergistically enhance cell/material interactions

Biochemical characterization of a recombinant thermoalkalophilic lipase and assessment of its substrate enantioselectivity

Biomaterials functionalized with nanoclusters of integrin- and syndecan-binding ligands improve cell adhesion and mechanosensing under shear flow conditions

Blood-borne amyloid-beta dimer correlates with clinical markers of Alzheimer's disease

Celogentin mimetics as inhibitors of tubulin polymerization

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry

Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase.

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity.

Copper-free palladium-catalyzed Sonogashira and Hiyama cross-couplings using aryl imidazol-1-ylsulfonates

Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli

Deprotection of pinacolyl boronate esters via hydrolysis of intermediate potassium trifluoroborates

Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis

Effects of PPAR gamma ligands on TGF-beta1-induced epithelial-mesenchymal transition in alveolar epithelial cells.

Enantioselective preparation of a stable boronate complex stereogenic only at boron

Establishing Signature Fragments for Identification and Sequencing of Dityrosine Cross-Linked Peptides Using Ultraviolet Photodissociation Mass Spectrometry

Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate

Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive.

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

Inhibiting protein-protein interactions as an emerging paradigm for drug discovery.

Inhibition of lysine biosynthesis: an evolving antibiotic strategy

Inhibitors of lysine biosynthesis as antibacterial agents

Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues

LC-MS and NMR characterization of the purple chromophore formed in the o-aminobenzaldehyde assay of dihydrodipicolinate synthase

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.

Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples.

One-step radiosynthesis of 4-nitrophenyl 2-[(18) F]fluoropropionate ([(18) F]NFP); improved preparation of radiolabeled peptides for PET imaging

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

Potentially Macrocyclic Peptidyl Boronic Acids as Chymotrypsin Inhibitors

Preparation of Cyclic Peptide Alkaloids Containing Functionalized Tryptophan Residues

Preparation of beta-nitroalanine using the Easton three-component coupling method

Preparation of diazabicyclo[4.3.0]nonene-based peptidomimetics

Preparation of the Central Tryptophan Moiety (I) of the Celogentin/Moroidin Family of Antimitotic Cyclic Peptides

Preparation of the Central Tryptophan Moiety of the Celogentin/Moroidin Family of Anti-Mitotic Cyclic Peptides

Rapid, Traceless, AgI -Promoted Macrocyclization of Peptides Possessing an N-Terminal Thioamide

Recent developments in radiolabelled peptides for PET imaging of cancer

Role of 2-oxo and 2-thioxo modifications on the fragmentation reactions of the histidine radical cation

Role of 2-oxo and 2-thioxo modifications on the proton affinity of histidine and fragmentation reactions of protonated histidine.

Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid β peptide

Structure of olefin-imidacloprid and gas-phase fragmentation chemistry of its protonated form.

Structure-Activity Relationships of cyclo(l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct

Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax

Sulfonation of Tyrosine as a Method To Improve Biodistribution of Peptide-Based Radiotracers: Novel 18F-Labeled Cyclic RGD Analogues

Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives.

Synthesis of Peptides by Silver-Promoted Coupling of Carboxylates and Thioamides: Mechanistic Insight from Computational Studies.

Synthesis of beta-hydroxy-beta-(fluoronitrophenyl)alanines: vital components in the assembly of biologically active cyclic peptides

Synthesis of cyclic peptide hemicryptophanes: enantioselective recognition of a chiral zwitterionic guest

Synthesis of the C-Terminal Macrocycle of Asperipin-2a

Synthesis of the beta-hydroxydopa-gamma-hydroxy-delta-sulfinylnorvaline component of ustiloxins A and B.

Synthesis of the side chain cross-linked tyrosine oligomers dityrosine, trityrosine, and pulcherosine.

Synthesis of β,γ-dihydroxyhomotyrosines by a tandem Petasis-asymmetric dihydroxylation approach

Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers

Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome

The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product ⬇️

The enantioselective synthesis of APTO and AETD: polyhydroxylated beta-amino acid constituents of the microsclerodermin cyclic peptides

Total Synthesis of Seongsanamide B

Total Synthesis of Ustiloxin D Utilizing an Ammonia-Ugi Reaction

Total Synthesis of the Putative Structure of Asperipin-2a and Stereochemical Reassignment

Total synthesis of (-)-reveromycin B

Total synthesis of mycocyclosin

Total synthesis of the epidermal growth factor inhibitor (-)-reveromycin B.

Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate.

Unimolecular reactivity of organotrifluoroborate anions, RBF3- , and their alkali metal cluster ions, M(RBF3 )2- (M = Na, K; R = CH3 , CH3 CH2 , CH3 (CH2 )3 , CH3 (CH2 )5 , c-C3 H5 , C6 H5 , C6 H5 CH2 , CH2 CHCH2 , CH2 CH, C6 H5 CO)