Lista de obras - Maria Pia Longhese - Dominio Público Uruguay

A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1.

artículo científico publicado en 2004

A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres

artículo científico publicado en 2012

A central role for DNA replication forks in checkpoint activation and response

artículo científico publicado en 2003

Analysis of De Novo Telomere Addition by Southern Blot

artículo científico publicado en 2018

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast

artículo científico publicado en 1999

Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway

artículo científico publicado en 2001

Coupling end resection with the checkpoint response at DNA double-strand breaks.

artículo científico publicado en 2016

DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends

scientific article published on 01 March 2020

DNA damage checkpoint in budding yeast.

artículo científico publicado en 1998

Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.

artículo científico publicado en 2010

Distinct Cdk1 requirements during single-strand annealing, noncrossover, and crossover recombination.

artículo científico publicado en 2011

Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response

artículo científico publicado en 2007

Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes

artículo científico publicado en 2021

Erratum: Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

article

Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection.

artículo científico publicado en 2015

Functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations

artículo científico publicado en 2007

G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint

artículo científico publicado en 2012

Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.

artículo científico publicado en 2001

Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

artículo científico publicado en 1999

Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks

artículo científico

Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.

artículo científico publicado en 2014

Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity

scientific article published on 24 August 2018

Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends

artículo científico publicado en 2013

Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

artículo científico publicado en 1998

Mechanisms and regulation of DNA end resection

scientific article published on 20 July 2010

Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres.

artículo científico publicado en 2009

Mutants with changes in different domains of yeast replication protein A exhibit differences in repairing the control region, the transcribed strand and the non-transcribed strand of the Saccharomyces cerevisiae MFA2 gene.

artículo científico publicado en 1998

PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response

artículo científico publicado en 2017

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

artículo científico publicado en 2004

RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA

artículo científico publicado en 2014

RPA regulates telomerase action by providing Est1p access to chromosome ends

artículo científico publicado en 2004

Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells.

artículo científico publicado en 2018

Regulation of telomere metabolism by the RNA processing protein Xrn1.

artículo científico publicado en 2017

Regulation of the DNA damage response by cyclin-dependent kinases.

artículo científico publicado en 2013

Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae

artículo científico publicado en 2015

Rif1 supports the function of the CST complex in yeast telomere capping.

artículo científico publicado en 2011

Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection.

artículo científico publicado en 2014

Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity

artículo científico publicado en 2015

Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres

artículo científico publicado en 2010

Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae

artículo científico publicado en 2003

Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends

artículo científico publicado en 2012

Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks

artículo científico publicado en 2016

Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase

artículo científico publicado en 2019

Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning.

artículo científico publicado en 2018

Telomere-end processing: mechanisms and regulation

artículo científico publicado en 2013

Telomeres and DNA damage checkpoints.

artículo científico publicado en 2004

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

artículo científico publicado en 2012

The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation

scientific article published on 01 April 2019

The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends

artículo científico publicado en 2010

The MRX complex regulates Exo1 resection activity by altering DNA end structure

artículo científico publicado en 2018

The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions

artículo científico publicado en 2008

The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1.

artículo científico publicado en 2017

The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing

artículo científico publicado en 2020

The Saccharomyces cerevisiae 14-3-3 proteins are required for the G1/S transition, actin cytoskeleton organization and cell wall integrity

artículo científico publicado en 2006

The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling

artículo científico publicado en 2006

The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends

artículo científico publicado en 2005

The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle

artículo científico publicado en 2008

The cellular response to chromosome breakage.

artículo científico publicado en 2006

The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation

artículo científico publicado en 2004

The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.

artículo científico publicado en 1997

The role of shelterin in maintaining telomere integrity

artículo científico publicado en 2012

Uncoupling Sae2 Functions in Downregulation of Tel1 and Rad53 Signaling Activities

article

Lista de obras de Maria Pia Longhese

A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1.

A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres

A central role for DNA replication forks in checkpoint activation and response

Analysis of De Novo Telomere Addition by Southern Blot

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast

Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway

Coupling end resection with the checkpoint response at DNA double-strand breaks.

DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends

DNA damage checkpoint in budding yeast.

Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.

Distinct Cdk1 requirements during single-strand annealing, noncrossover, and crossover recombination.

Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response

Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes

Erratum: Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection.

Functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations

G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint

Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.

Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks

Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.

Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity

Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends

Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

Mechanisms and regulation of DNA end resection

Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres.

Mutants with changes in different domains of yeast replication protein A exhibit differences in repairing the control region, the transcribed strand and the non-transcribed strand of the Saccharomyces cerevisiae MFA2 gene.

PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA

RPA regulates telomerase action by providing Est1p access to chromosome ends

Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells.

Regulation of telomere metabolism by the RNA processing protein Xrn1.

Regulation of the DNA damage response by cyclin-dependent kinases.

Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae

Rif1 supports the function of the CST complex in yeast telomere capping.

Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection.

Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity

Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres

Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae

Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends

Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks

Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase

Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning.

Telomere-end processing: mechanisms and regulation

Telomeres and DNA damage checkpoints.

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation

The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends

The MRX complex regulates Exo1 resection activity by altering DNA end structure

The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions

The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1.

The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing

The Saccharomyces cerevisiae 14-3-3 proteins are required for the G1/S transition, actin cytoskeleton organization and cell wall integrity

The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling

The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends

The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle

The cellular response to chromosome breakage.

The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation

The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.

The role of shelterin in maintaining telomere integrity

Uncoupling Sae2 Functions in Downregulation of Tel1 and Rad53 Signaling Activities