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Lista de obras de Mary Jackson

2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain

artículo científico publicado en 2019

2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.

artículo científico publicado en 2017

A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in <i>Mycobacterium tuberculosis</i>

artículo científico publicado en 2021

A Noncompetitive Inhibitor for Mycobacterium tuberculosis ’s Class IIa Fructose 1,6-Bisphosphate Aldolase

artículo científico publicado en 2014

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone

artículo científico publicado en 2012

A glycomic approach reveals a new mycobacterial polysaccharide

artículo científico publicado en 2015

A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra

artículo científico publicado en 2007

A single arabinan chain is attached to the phosphatidylinositol mannosyl core of the major immunomodulatory mycobacterial cell envelope glycoconjugate, lipoarabinomannan

artículo científico publicado en 2014

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria

artículo científico publicado en 2012

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

artículo científico publicado en 2009

Aldehyde-resistant mycobacteria bacteria associated with the use of endoscope reprocessing systems

artículo científico publicado en 2012

An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages

scientific journal article

Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles

scientific article published on 04 November 2019

Analysis of a panel of rapidly growing mycobacteria for resistance to aldehyde-based disinfectants

artículo científico publicado en 2014

Analysis of uracil phosphoribosyltransferase expression in Mycobacterium tuberculosis and evaluation of upp knockout strain in infected mice

artículo científico publicado en 2017

Assembling of the Mycobacterium tuberculosis Cell Wall Core

artículo científico publicado en 2016

Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis

artículo científico publicado en 2013

Biochemical and microbiological evaluation of N-aryl urea derivatives against mycobacteria and mycobacterial hydrolases

artículo científico publicado en 2019

Biosynthesis and translocation of unsulfated acyltrehaloses in Mycobacterium tuberculosis

artículo científico publicado en 2014

Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase

scientific journal article

Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis

artículo científico publicado en 2017

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis

scientific journal article

Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

scientific journal article

Cell wall core galactofuran synthesis is essential for growth of mycobacteria

artículo científico publicado en 2001

Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis

artículo científico publicado en 2009

Characterization of Arabinosyl Transfer Reactions in the Biosynthesis of Mycobacterial Cell Envelope (Lipo)Polysaccharides

artículo científico publicado en 2019

Cloning and Partial Characterization of an Endo-α-(1→6)-d-Mannanase Gene from Bacillus circulans ⬇️

artículo científico publicado en 2019

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

artículo científico publicado en 2006

Cooccurrence of free-living amoebae and nontuberculous Mycobacteria in hospital water networks, and preferential growth of Mycobacterium avium in Acanthamoeba lenticulata

artículo científico publicado en 2013

Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone

artículo científico publicado en 2015

Covalent modifications of polysaccharides in mycobacteria

artículo científico publicado en 2018

CpsA, a LytR-CpsA-Psr Family Protein in Mycobacterium marinum, Is Required for Cell Wall Integrity and Virulence

artículo científico publicado en 2015

Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis

artículo científico publicado en 2005

Cytokinin Signaling in Mycobacterium tuberculosis.

artículo científico publicado en 2018

DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells

artículo científico publicado en 2003

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

artículo científico publicado en 2005

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2

artículo científico publicado en 2018

Deficiency in mycolipenate- and mycosanoate-derived acyltrehaloses enhances early interactions of Mycobacterium tuberculosis with host cells

artículo científico publicado en 2003

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

scientific journal article

Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties

artículo científico publicado en 2013

Design, synthesis and evaluation of indole-2-carboxamides with pan anti-mycobacterial activity

artículo científico publicado en 2017

Direct Inhibition of MmpL3 by Novel Antitubercular Compounds

scientific article published on 28 March 2019

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.

artículo científico publicado en 2013

Disinfectant Susceptibility Profiling of Glutaraldehyde-Resistant Nontuberculous Mycobacteria

artículo científico publicado en 2017

Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides

artículo científico publicado en 2019

Draft Genome Sequence of Mycobacterium chelonae Type Strain ATCC 35752.

artículo científico publicado en 2015

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

artículo científico publicado en 1997

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

artículo científico publicado en 2018

Gene replacement in Mycobacterium chelonae: application to the construction of porin knock-out mutants

artículo científico publicado en 2014

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis

scientific journal article

Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids

artículo científico publicado en 2014

Genome Sequence of an Epidemic Isolate of Mycobacterium abscessus subsp. bolletii from Rio de Janeiro, Brazil

artículo científico publicado en 2013

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

artículo científico publicado en 2011

Green Fluorescent Protein as a protein localization and topological reporter in mycobacteria

artículo científico publicado en 2017

HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8+ T cells

artículo científico publicado en 2017

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

artículo científico publicado en 2009

High-level relatedness among Mycobacterium abscessus subsp. massiliense strains from widely separated outbreaks

artículo científico publicado en 2014

Identification and functional analysis of a galactosyltransferase capable of cholesterol glycolipid formation in the Lyme disease spirochete Borrelia burgdorferi

artículo científico publicado en 2021

Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance

scientific article published on 23 September 2019

Identification of a Novel Mycobacterial Arabinosyltransferase Activity Which Adds an Arabinosyl Residue to α-d-Mannosyl Residues

artículo científico publicado en 2016

Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides

scientific journal article

Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species

scientific journal article

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

artículo científico publicado en 2007

Impact of the deletion of the six mce operons in Mycobacterium smegmatis

artículo científico publicado en 2012

Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria.

artículo científico publicado en 2018

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

scientific journal article

Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis

artículo científico publicado en 2014

Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope

scientific journal article

Increased virulence of an epidemic strain of Mycobacterium massiliense in mice

artículo científico publicado en 2011

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

scientific journal article

Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria

artículo científico publicado en 2009

Interactions of free-living amoebae with rice bacterial pathogens Xanthomonas oryzae pathovars oryzae and oryzicola

scientific article published in PLoS ONE

Interactions of free-living amoebae with the rice fungal pathogen, Rhizoctonia solani

scientific article published on 15 November 2019

Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster

artículo científico publicado en 2011

Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis

artículo científico publicado en 2007

Lipoarabinomannan of Mycobacterium: mannose capping by a multifunctional terminal mannosyltransferase

scientific journal article

Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: biosynthesis, transport, regulation and biological activities

artículo científico publicado en 2006

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts

artículo científico publicado en 2014

LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis

scientific journal article

LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis

artículo científico publicado en 2014

Mce3R, a TetR-type transcriptional repressor, controls the expression of a regulon involved in lipid metabolism in Mycobacterium tuberculosis

scientific journal article

Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen

artículo científico publicado en 2013

Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in Mycobacterium tuberculosis

scientific article published on 11 December 2019

Mechanistic Insights into the Retaining Glucosyl-3-phosphoglycerate Synthase from Mycobacteria

artículo científico publicado en 2012

Metabolic profile of Mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis

MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections.

artículo científico publicado en 2018

Molecular basis of phosphatidyl-myo-inositol mannoside biosynthesis and regulation in mycobacteria

artículo científico publicado en 2010

Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria

artículo científico publicado en 2007

Mycobacterium bovis hosted by free-living-amoebae permits their long-term persistence survival outside of host mammalian cells and remain capable of transmitting disease to mice.

artículo científico publicado en 2017

Mycobacterium talmoniae sp. nov., a slowly growing mycobacterium isolated from human respiratory samples

artículo científico

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.

artículo científico publicado en 2017

Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion

artículo científico publicado en 2014

N-D-aldopentofuranosyl-N'-[p-(isoamyloxy)phenyl]-thiourea derivatives: potential anti-TB therapeutic agents

artículo científico publicado en 2008

New insights into the biosynthesis of mycobacterial lipomannan arising from deletion of a conserved gene

artículo científico publicado en 2007

New insights into the early steps of phosphatidylinositol mannoside biosynthesis in mycobacteria: PimB' is an essential enzyme of Mycobacterium smegmatis

scientific journal article

Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis

artículo científico publicado en 2014

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

scientific article published on 20 September 2018

Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

scientific journal article

Phosphatidylinositol is an essential phospholipid of mycobacteria

scientific journal article

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis

scientific journal article

Phylogenomics of Brazilian epidemic isolates of Mycobacterium abscessus subsp. bolletii reveals relationships of global outbreak strains

artículo científico publicado en 2013

Polymethylated polysaccharides from Mycobacterium species revisited

artículo científico publicado en 2008

Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis

artículo científico publicado en 2008

Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection

artículo científico publicado en 2004

Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis

artículo científico publicado en 2013

Purification and characterization of the acyltransferase involved in biosynthesis of the major mycobacterial cell envelope glycolipid--monoacylated phosphatidylinositol dimannoside.

artículo científico publicado en 2014

RND transporters protect Corynebacterium glutamicum from antibiotics by assembling the outer membrane

artículo científico publicado en 2014

Rational Design, Synthesis, and Evaluation of New Selective Inhibitors of Microbial Class II (Zinc Dependent) Fructose Bis-phosphate Aldolases

artículo científico publicado en 2010

Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors

artículo científico publicado en 2011

Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection

artículo científico publicado en 2005

Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source

artículo científico publicado en 2013

Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs

artículo científico publicado en 2009

Role of the Mce1 transporter in the lipid homeostasis of Mycobacterium tuberculosis

artículo científico publicado en 2014

Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability

artículo científico publicado en 2012

Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages

artículo científico publicado en 2006

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.

artículo científico publicado en 2016

Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis

artículo científico publicado en 2016

Structure-function relationships of membrane-associated GT-B glycosyltransferases

artículo científico publicado en 2013

Subfractionation and analysis of the cell envelope (lipo)polysaccharides of Mycobacterium tuberculosis

artículo científico publicado en 2013

Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis

scientific article published on 11 June 2009

Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigs

artículo científico publicado en 2003

Synergistic Interactions of MmpL3 Inhibitors with Antitubercular Compounds In Vitro

artículo científico publicado en 2017

Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics

artículo científico publicado en 2008

Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis

artículo científico publicado en 2016

Synthesis, biological activity, and evaluation of the mode of action of novel antitubercular benzofurobenzopyrans substituted on A ring

artículo científico publicado en 2010

Taxonomic characterization of nine strains isolated from clinical and environmental specimens, and proposal of Corynebacterium tuberculostearicum sp. nov.

artículo científico publicado en 2004

The MmpL3 interactome reveals a complex crosstalk between cell envelope biosynthesis and cell elongation and division in mycobacteria

artículo científico publicado en 2019

The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth

scientific journal article

The cell envelope glycoconjugates of Mycobacterium tuberculosis

artículo científico publicado en 2014

The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan

artículo científico publicado en 2002

The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates

artículo científico publicado en 2007

The immunomodulatory lipoglycans, lipoarabinomannan and lipomannan, are exposed at the mycobacterial cell surface

artículo científico publicado en 2008

The mycobacterial cell envelope-lipids

artículo científico publicado en 2014

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

artículo científico publicado en 2015

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria

artículo científico publicado en 2006

The structure-activity relationship of urea derivatives as anti-tuberculosis agents

artículo científico publicado en 2011

The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis

scientific journal article

Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3

artículo científico publicado en 2016

Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis

scientific journal article

Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope

artículo científico publicado en 2020

Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in <i>Mycobacterium tuberculosis</i>

scientific article published on 15 December 2020

Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis

artículo científico publicado en 2003

Updating and curating metabolic pathways of TB.

artículo científico

Use of Synthetic Glycolipids to Probe the Number and Position of Arabinan Chains on Mycobacterial Arabinogalactan

scientific article published on 31 December 2020

Virulence attenuation of two Mas-like polyketide synthase mutants of Mycobacterium tuberculosis

scientific journal article

Yersinia pestis Survival and Replication in Potential Ameba Reservoir.

artículo científico publicado en 2018

p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis

scientific journal article

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