Filtros de búsqueda

Lista de obras de Glenn F King

1H, 13C and 15N NMR assignments of two plant protease inhibitors (IRD7 and IRD12) from the plant Capsicum annuum

scientific article published on 18 September 2018

31. Spider-venom Peptides that Target the Human NaV1.7 channel: Potential Analgesics for the Treatment of Chronic Pain

32. Development of High Throughput Calcium Channel Assays to Accelerate the Discovery of Novel Toxins Targeting Human Cav2.2 Channels

scholarly article by Silmara R. Sousa et al published August 2012 in Toxicon

A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain

scientific article published on 22 August 2019

A Strategy for Production of Correctly Folded Disulfide-Rich Peptides in the Periplasm of E. coli.

artículo científico publicado en 2017

A Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating Domain

artículo científico publicado en 2014

A Versatile and Robust Serine Protease Inhibitor Scaffold from Actinia tenebrosa

scientific article published on 12 December 2019

A comprehensive portrait of the venom of the giant red bull ant, , reveals a hyperdiverse hymenopteran toxin gene family

article

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

artículo científico publicado en 2014

A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a

artículo científico publicado en 2011

A model genetic system for testing the in vivo function of peptide toxins.

artículo científico publicado en 2006

A non-uniformly sampled 4D HCC(CO)NH-TOCSY experiment processed using maximum entropy for rapid protein sidechain assignment

artículo científico publicado en 2010

A pain-causing and paralytic ant venom glycopeptide

artículo científico publicado en 2021

A process of convergent amplification and tissue-specific expression dominates the evolution of toxin and toxin-like genes in sea anemones

artículo científico publicado en 2019

A proteomics and transcriptomics investigation of the venom from the barychelid spider Trittame loki (brush-foot trapdoor)

artículo científico publicado en 2013

A proton n.m.r. study of iminodipeptide transport and hydrolysis in the human erythrocyte. Possible physiological roles for the coupled system

artículo científico publicado en 1984

A rational nomenclature for naming peptide toxins from spiders and other venomous animals

artículo científico publicado en 2008

A selective naV1.1 activator with potential for treatment of dravet syndrome epilepsy

scientific article published on 23 April 2020

A sequence similarity between proteins involved in initiation and termination of bacterial chromosome replication

artículo científico publicado en 1991

A spider-venom peptide with multi-target activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome

scientific article published on 17 August 2020

Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of NaV1.7.

artículo científico publicado en 2020

Animal toxins - Nature's evolutionary-refined toolkit for basic research and drug discovery

artículo científico publicado en 2020

Aphicidal efficacy of scorpion- and spider-derived neurotoxins

artículo científico publicado en 2013

Application of progress curve analysis to in situ enzyme kinetics using 1H NMR spectroscopy

artículo científico publicado en 1986

ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures

artículo científico publicado en 2011

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins.

artículo científico publicado en 2017

ArachnoServer: a database of protein toxins from spiders

artículo científico publicado en 2009

Artificial septal targeting of Bacillus subtilis cell division proteins in Escherichia coli: an interspecies approach to the study of protein-protein interactions in multiprotein complexes

scientific journal article

Assimilation of alpha-glutamyl-peptides by human erythrocytes. A possible means of glutamate supply for glutathione synthesis

artículo científico publicado en 1985

Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators

scientific article published on 21 September 2020

Australian funnel-web spiders: master insecticide chemists.

artículo científico publicado en 2004

Backbone and side chain NMR assignments of Geobacillus stearothermophilus ZapA allow identification of residues that mediate the interaction of ZapA with FtsZ.

artículo científico publicado en 2015

Backbone and side-chain 1H, 15N and 13C assignments for the cis conformer of the beta domain of the bacterial cell division protein DivIB.

artículo científico publicado en 2005

Backbone and side-chain 1H, 15N, and 13C assignments for chick cofilin

artículo científico publicado en 2002

Backbone and side-chain 1H, 15N, and 13C assignments for the beta domain of the bacterial cell division protein DivIB.

artículo científico publicado en 2005

Backbone and side-chain 1H, 15N, and 13C assignments for the topological specificity domain of the MinE cell division protein

scientific article published on 01 April 1999

Backbone dynamics of the c-Jun leucine zipper: 15N NMR relaxation studies

artículo científico publicado en 1996

Bimodal Imaging of Mouse Peripheral Nerves with Chlorin Tracers

artículo científico publicado en 2021

Buzz Kill: Function and Proteomic Composition of Venom from the Giant Assassin Fly (Diptera: Asilidae)

article

Calculation of symmetric multimer structures from NMR data using a priori knowledge of the monomer structure, co-monomer restraints, and interface mapping: The case of leucine zippers.

artículo científico publicado en 1996

Can we resolve the taxonomic bias in spider venom research?

scientific article published on 02 January 2019

Centipede venom: recent discoveries and current state of knowledge

artículo científico publicado en 2015

Centipede venoms as a source of drug leads.

artículo científico publicado en 2016

Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica.

artículo científico publicado en 2016

Characterization of peptide fluxes into human erythrocytes. A proton-n.m.r. study

artículo científico publicado en 1990

Chemical punch packed in venoms makes centipedes excellent predators

artículo científico publicado en 2012

Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3.

artículo científico publicado en 2009

Chemical synthesis and structure of the prokineticin Bv8

artículo científico publicado en 2010

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

artículo científico publicado en 2014

Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (centipedes)

artículo científico publicado en 2014

Cloning and activity of a novel α-latrotoxin from red-back spider venom

artículo científico publicado en 2012

Cloning, expression, and spectroscopic studies of the Jun leucine zipper domain.

artículo científico publicado en 1994

Combination of Ambiguous and Unambiguous Data in the Restraint-driven Docking of Flexible Peptides with HADDOCK: The Binding of the Spider Toxin PcTx1 to the Acid Sensing Ion Channel (ASIC) 1a.

artículo científico publicado en 2015

Comparison of the peptidome and insecticidal activity of venom from a taxonomically diverse group of theraphosid spiders

artículo científico publicado en 2009

Conformation of sarafotoxin-6b in aqueous solution determined by NMR spectroscopy and distance geometry.

artículo científico publicado en 1991

Construction of a hypervirulent and specific mycoinsecticide for locust control.

artículo científico publicado en 2014

Correction: Molecular Evolution of Vertebrate Neurotrophins: Co-Option of the Highly Conserved Nerve Growth Factor Gene into the Advanced Snake Venom Arsenalf.

artículo científico publicado en 2013

Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.

artículo científico publicado en 2017

Crouching Tiger, Hidden Protein: Searching for Insecticidal Toxins in Venom of the Red Tiger Assassin Bug (<i>Havinthus rufovarius</i>)

artículo científico publicado en 2020

Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3

artículo científico publicado en 2012

Cyclization of peptides by using selenolanthionine bridges.

artículo científico publicado en 2012

Deadly Proteomes: a Practical Guide to Proteotranscriptomics of Animal Venoms

artículo científico publicado en 2020

Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data

artículo científico publicado en 2016

Determination of the solution structure of a platelet-adhesion peptide of von Willebrand factor

scientific article published on 01 November 1992

Determination of the structure of symmetric coiled-coil proteins from NMR data: application of the leucine zipper proteins Jun and GCN4.

artículo científico publicado en 1993

Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms

artículo científico publicado en 2019

Development of a rational nomenclature for naming peptide and protein toxins from sea anemones.

artículo científico publicado en 2012

Development of a sensitive peptide-based immunoassay: application to detection of the Jun and Fos oncoproteins.

artículo científico publicado en 1996

Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains.

artículo científico publicado en 2012

Differential evolution and neofunctionalization of snake venom metalloprotease domains

artículo científico publicado en 2012

Differential hydrolysis of erythrocyte and mitochondrial membrane phospholipids by two phospholipase A2 isoenzymes (NK-PLA2-I and NK-PLA2-II) from the venom of the Indian monocled cobra Naja kaouthia

artículo científico publicado en 2004

Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins

artículo científico publicado en 2018

Direct NMR evidence that prolidase is specific for the trans isomer of imidodipeptide substrates.

artículo científico publicado en 1986

Direct visualization of disulfide bonds through diselenide proxies using 77Se NMR spectroscopy

artículo científico publicado en 2009

Discovery and characterisation of novel peptides from Amazonian stinging ant venoms with antiparasitic activity

artículo científico publicado en 2020

Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge

artículo científico publicado en 2000

Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

artículo científico publicado en 2017

Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models

artículo científico publicado en 2013

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

artículo científico publicado en 2014

Division site placement in E.coli: mutations that prevent formation of the MinE ring lead to loss of the normal midcell arrest of growth of polar MinD membrane domains

artículo científico publicado en 2002

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?

artículo científico publicado en 2013

Domain architecture and structure of the bacterial cell division protein DivIB

artículo científico publicado en 2006

Dracula's children: molecular evolution of vampire bat venom.

artículo científico publicado en 2013

Efficient Enzymatic Ligation of Inhibitor Cystine Knot Spider Venom Peptides: Using Sortase A To Form Double-Knottins That Probe Voltage-Gated Sodium Channel NaV1.7.

scientific article published on 12 September 2018

Enkephalin degradation by human erythrocytes and hemolysates studied using 1H NMR spectroscopy.

artículo científico publicado en 1985

Entomo-venomics: The evolution, biology and biochemistry of insect venoms

scientific article published on 26 September 2018

Erratum: Corrigendum: Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy

article

Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides

article

Evidence from artificial septal targeting and site-directed mutagenesis that residues in the extracytoplasmic β domain of DivIB mediate its interaction with the divisomal transpeptidase PBP 2B

scientific journal article

Fifteen years of NaV 1.7 as an analgesic target: why has excellent in vitropharmacology not translated into in vivo analgesic efficacy?

artículo científico publicado en 2020

Fluorescence Imaging of Peripheral Nerves by a Nav1.7-Targeted Inhibitor Cystine Knot Peptide

scientific article published on 08 November 2019

Fluorescence labeling of a NaV1.7-targeted peptide for near-infrared nerve visualization

artículo científico publicado en 2020

From foe to friend: using animal toxins to investigate ion channel function

artículo científico publicado en 2015

From kinetics to imaging: an NMR odyssey--a festschrift symposium in honour of Philip William Kuchel

artículo científico publicado en 2013

Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms

artículo científico publicado en 2013

Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3.

artículo científico publicado en 2012

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6.

artículo científico publicado en 2014

Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a

artículo científico publicado en 2001

Fusion to snowdrop lectin magnifies the oral activity of insecticidal ω-Hexatoxin-Hv1a peptide by enabling its delivery to the central nervous system

artículo científico publicado en 2012

Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes

artículo científico publicado en 2018

Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family

Giant fish-killing water bug reveals ancient and dynamic venom evolution in Heteroptera.

artículo científico publicado en 2018

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation

artículo científico publicado en 2018

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.

artículo científico publicado en 2018

Harvesting Venom Toxins from Assassin Bugs and Other Heteropteran Insects

artículo científico publicado en 2018

Heterodimeric Insecticidal Peptide Provides New Insights into the Molecular and Functional Diversity of Ant Venoms

scientific article published on 06 October 2020

High resolution 1H NMR study of the solution structure of the S4 segment of the sodium channel protein

artículo científico publicado en 1989

High resolution NMR solution structure of the leucine zipper domain of the c-Jun homodimer

artículo científico publicado en 1996

Histidine kinases as antimicrobial targets: prospects and pitfalls.

artículo científico publicado en 2007

Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens

artículo científico publicado en 2015

Identification and Functional Characterization of Sugarcane Invertase Inhibitor (ShINH1): A Potential Candidate for Reducing Pre- and Post-harvest Loss of Sucrose in Sugarcane.

artículo científico publicado en 2018

Improved efficacy of an arthropod toxin expressing fungus against insecticide-resistant malaria-vector mosquitoes

artículo científico publicado en 2017

Inhibition and active-site modelling of prolidase.

artículo científico publicado en 1989

Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.

artículo científico publicado en 2017

Insect-Active Toxins with Promiscuous Pharmacology from the African Theraphosid Spider Monocentropus balfouri

artículo científico publicado en 2017

Insecticidal activity of a recombinant knottin peptide from Loxosceles intermedia venom and recognition of these peptides as a conserved family in the genus.

artículo científico publicado en 2016

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain

artículo científico publicado en 2011

Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.

artículo científico publicado en 2016

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

artículo científico publicado en 2014

Involvement of the N-finger in the self-association of GATA-1.

artículo científico publicado en 1998

Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus

artículo científico publicado en 2016

Isolation and pharmacological characterisation of delta-atracotoxin-Hv1b, a vertebrate-selective sodium channel toxin

artículo científico publicado en 2000

Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1.

artículo científico publicado en 2000

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula

artículo científico publicado en 2013

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix

artículo científico publicado en 2016

Isolation, synthesis and characterization of ω-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type Cav channels

artículo científico publicado en 2014

It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant Myrmecia pilosula

artículo científico publicado en 2020

Key residues characteristic of GATA N-fingers are recognized by FOG.

artículo científico publicado en 1998

Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function

artículo científico publicado en 2012

Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination

artículo científico publicado en 2011

Macromolecular NMR spectroscopy for the non‐spectroscopist ⬇️

artículo científico publicado el 28 de enero de 2011

Managing local swelling following intratumoral electro-chemo-gene therapy

artículo científico publicado en 2014

Mapping the MinE site involved in interaction with the MinD division site selection protein of Escherichia coli

artículo científico publicado en 2003

Mapping the Phosphoinositide-Binding Site on Chick Cofilin Explains How PIP2 Regulates the Cofilin-Actin Interaction

artículo científico publicado en 2006

Measuring macromolecular diffusion using heteronuclear multiple-quantum pulsed-field-gradient NMR.

artículo científico publicado en 1997

Measuring protein self-association using pulsed-field-gradient NMR spectroscopy: application to myosin light chain 2

artículo científico publicado en 1995

Melt With This Kiss: Paralyzing and Liquefying Venom of The Assassin Bug Pristhesancus plagipennis (Hemiptera: Reduviidae).

artículo científico publicado en 2017

Membrane localization of MinD is mediated by a C-terminal motif that is conserved across eubacteria, archaea, and chloroplasts

artículo científico publicado en 2002

Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating

artículo científico publicado en 2016

Missiles of Mass Disruption: Composition and Glandular Origin of Venom Used as a Projectile Defensive Weapon by the Assassin Bug Platymeris rhadamanthus

artículo científico publicado en 2019

Modulation of insect Ca(v) channels by peptidic spider toxins.

artículo científico publicado en 2006

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus.

artículo científico publicado en 2017

Molecular basis of the interaction between gating modifier spider toxins and the voltage sensor of voltage-gated ion channels.

scientific article published on 28 September 2016

Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami

artículo científico publicado en 2016

Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid-sensing ion channel 1a.

artículo científico publicado en 2015

Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenalf

artículo científico publicado en 2013

Molecular phylogeny and evolution of the proteins encoded by coleoid (cuttlefish, octopus, and squid) posterior venom glands

artículo científico publicado en 2013

Monitoring metabolic reactions in erythrocytes using NMR spectroscopy

scientific article published on 01 January 1984

Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts

artículo científico publicado en 2014

Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target NaV1.7.

artículo científico publicado en 2020

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy

artículo científico publicado en 2014

NMR methods for determining disulfide-bond connectivities

artículo científico publicado en 2010

NMR methods for measuring membrane transport

artículo científico publicado en 1994

NMR spectroscopy and X-ray crystallography provide complementary information on the structure and dynamics of leucine zippers

artículo científico publicado en 1996

NMR structure and dynamics of inhibitory repeat domain variant 12, a plant protease inhibitor from Capsicum annuum, and its structural relationship to other plant protease inhibitors

scientific article published on 30 April 2019

NaV1.1 inhibition can reduce visceral hypersensitivity

artículo científico publicado en 2018

No evidence for bradykinin hydrolysis in human erythrocyte suspensions: 1H NMR studies

artículo científico publicado en 1987

No evidence of high capacity alpha-glutamyl-dipeptide transport into human erythrocytes

artículo científico publicado en 1987

No gain, no pain: NaV1.7 as an analgesic target

artículo científico publicado en 2014

Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target

artículo científico publicado en 2018

Nuclear magnetic resonance characterization of the Jun leucine zipper domain: unusual properties of coiled-coil interfacial polar residues

artículo científico publicado en 1995

Olfactory bulb targeted QD bioconjugate and Kv1.3 blocking peptide improve metabolic health in obese male mice

scientific article published on 25 September 2020

On the venom system of centipedes (Chilopoda), a neglected group of venomous animals

scientific article published on 19 January 2011

Orally active acaricidal peptide toxins from spider venom.

artículo científico publicado en 2005

PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold

article

PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a.

artículo científico publicado en 2015

Peptide toxins that selectively target insect Na(V) and Ca(V) channels

artículo científico publicado en 2008

Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation - Suggestion of a Binding Mode at the α7 nAChR

artículo científico publicado en 2019

Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a

artículo científico publicado en 2017

Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases

artículo científico publicado en 2011

Positioning of the MinE binding site on the MinD surface suggests a plausible mechanism for activation of the Escherichia coli MinD ATPase during division site selection

artículo científico publicado en 2004

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.

artículo científico publicado en 2017

Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraint

artículo científico publicado en 2015

Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli.

artículo científico publicado en 2013

Proteomics and deep sequencing comparison of seasonally active venom glands in the platypus reveals novel venom peptides and distinct expression profiles.

artículo científico publicado en 2012

Proton NMR spectroscopic studies of dipeptidase in human erythrocytes

artículo científico publicado en 1983

Quantitation of metabolites of isolated chicken enterocytes using NMR spectroscopy

artículo científico publicado en 1989

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.

artículo científico publicado en 2015

Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers

artículo científico publicado en 2012

Regulation of RhoGEF activity by intramolecular and intermolecular SH3 domain interactions

artículo científico publicado en 2006

Reorganization of terminator DNA upon binding replication terminator protein: implications for the functional replication fork arrest complex.

artículo científico publicado en 1997

Revisiting venom of the sea anemone Stichodactyla haddoni: Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus.

artículo científico publicado en 2017

Role of interfacial hydrophobic residues in the stabilization of the leucine zipper structures of the transcription factors c-Fos and c-Jun

artículo científico publicado en 2001

Role of the PAS sensor domains in the Bacillus subtilis sporulation kinase KinA.

artículo científico publicado en 2013

Role of the structurally disordered N- and C-terminal residues in the Janus-faced atracotoxins

artículo científico publicado en 2002

SVM-based prediction of propeptide cleavage sites in spider toxins identifies toxin innovation in an Australian tarantula.

artículo científico publicado en 2013

Safe and effective treatment of spontaneous neoplasms with interleukin 12 electro-chemo-gene therapy

artículo científico publicado en 2015

Safety and efficacy of tumor-targeted interleukin 12 gene therapy in treated and non-treated, metastatic lesions

artículo científico publicado en 2015

Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function

artículo científico publicado en 2002

Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels

artículo científico publicado en 2004

Sea Anemone Toxins: A Structural Overview ⬇️

artículo científico publicado en 2019

Selective Na1.1 activation rescues Dravet syndrome mice from seizures and premature death

article published in the Proceedings of the National Academy of Sciences of the United States of America

Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury

artículo científico publicado en 2016

Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain

scientific journal article

Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain

scientific article published in Nature Communications

Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach

artículo científico publicado en 2015

Site-Specific pKa Determination of Selenocysteine Residues in Selenovasopressin by Using 77Se NMR Spectroscopy

artículo científico publicado en 2011

Site-directed mutants of RTP of Bacillus subtilis and the mechanism of replication fork arrest.

artículo científico publicado en 1999

Solution structure of endothelin-3 determined using NMR spectroscopy ⬇️

artículo científico publicado el 23 de junio de 1992

Spectroscopic identification of a dinuclear metal centre in manganese(II)-activated aminopeptidase P from Escherichia coli: implications for human prolidase

artículo científico publicado en 1998

Spider venomics: implications for drug discovery.

artículo científico publicado en 2014

Spider-venom peptides as bioinsecticides

artículo científico publicado en 2012

Spider-venom peptides as therapeutics.

artículo científico publicado en 2010

Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads.

artículo científico

Spider-venom peptides: structure, pharmacology, and potential for control of insect pests.

artículo científico publicado en 2012

Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles.

artículo científico publicado en 2013

Structural and biochemical studies of human galanin: NMR evidence for nascent helical structures in aqueous solution.

artículo científico publicado en 1995

Structural and molecular diversification of the Anguimorpha lizard mandibular venom gland system in the arboreal species Abronia graminea

artículo científico publicado en 2012

Structural basis for the modulation of voltage-gated sodium channels by animal toxins

artículo científico publicado en 2018

Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom

artículo científico publicado en 2019

Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene

scientific article published on 12 May 2020

Structure and mechanism of action of Sda, an inhibitor of the histidine kinases that regulate initiation of sporulation in Bacillus subtilis

artículo científico publicado en 2004

Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state

artículo científico publicado en 2009

Structure-function studies of omega-atracotoxin, a potent antagonist of insect voltage-gated calcium channels

artículo científico publicado en 1999

Studies of rat brain metabolism using proton nuclear magnetic resonance: spectral assignments and monitoring of prolidase, acetylcholinesterase, and glutaminase.

artículo científico publicado en 1984

Tandem use of selective insecticides and natural enemies for effective, reduced-risk pest management

scholarly article by Margaret C Hardy et al published March 2010 in Biological Control

The Bacillus subtilis DNA replication terminator.

artículo científico publicado en 1996

The Bacillus subtilis cell division proteins FtsL and DivIC are intrinsically unstable and do not interact with one another in the absence of other septasomal components.

artículo científico publicado en 2002

The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin ω-Hexatoxin-Hv1a

artículo científico publicado en 2015

The Generation of1H-NMR-Detectable Mobile Lipid in Stimulated Lymphocytes: Relationship to Cellular Activation, the Cell Cycle, and Phosphatidylcholine-Specific Phospholipase C ⬇️

artículo científico publicado el 29 de octubre de 1997

The Janus-faced atracotoxins are specific blockers of invertebrate K(Ca) channels.

artículo científico publicado en 2008

The MinD membrane targeting sequence is a transplantable lipid-binding helix

artículo científico publicado en 2003

The North American Society of Toxinology establishes formal affiliation with Toxicon.

artículo científico publicado en 2017

The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation

artículo científico publicado en 2011

The Structure of the KinA-Sda Complex Suggests an Allosteric Mechanism of Histidine Kinase Inhibition

artículo científico publicado en 2007

The Use of Imaging Mass Spectrometry to Study Peptide Toxin Distribution in Australian Sea Anemones

artículo científico publicado en 2017

The Vps4 C-terminal helix is a critical determinant for assembly and ATPase activity and has elements conserved in other members of the meiotic clade of AAA ATPases

artículo científico publicado en 2008

The antiproliferative profile of a linear octopus-derived peptide in melanoma of BRAF-mutation

scientific article published on 01 April 2020

The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro

scientific article published on 19 May 2019

The assassin bug Pristhesancus plagipennis produces two distinct venoms in separate gland lumens

artículo científico publicado en 2018

The assimilation of tri- and tetrapeptides by human erythrocytes.

artículo científico publicado en 1985

The dimerization and topological specificity functions of MinE reside in a structurally autonomous C-terminal domain.

artículo científico publicado en 1999

The dimerization function of MinC resides in a structurally autonomous C-terminal domain

artículo científico publicado en 2001

The divisomal protein DivIB contains multiple epitopes that mediate its recruitment to incipient division sites.

artículo científico publicado en 2008

The future of venoms-based drug discovery: an interview with Glenn King

artículo científico publicado en 2014

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels

artículo científico publicado en 2013

The insecticidal potential of venom peptides

artículo científico

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

artículo científico publicado en 2015

The lethal toxin from Australian funnel-web spiders is encoded by an intronless gene

artículo científico publicado en 2012

The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype- and species-dependent: Importance of interactions at the channel subunit interface and potential for engineering selective analogues

artículo científico publicado en 2019

The omega-atracotoxins: selective blockers of insect M-LVA and HVA calcium channels

artículo científico publicado en 2007

The relationship between hetero-oligomer formation and function of the topological specificity domain of the Escherichia coli MinE protein

artículo científico publicado en 1998

The solution structure of sarafotoxin-c. Implications for ligand recognition by endothelin receptors

artículo científico publicado en 1994

The solution structure of the leucine zipper motif of the Jun oncoprotein homodimer

artículo científico publicado en 1993

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

artículo científico publicado en 2010

The structure of versutoxin (delta-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel

artículo científico publicado en 1997

The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.

artículo científico publicado en 2017

The tale of a resting gland: transcriptome of a replete venom gland from the scorpion Hottentotta judaicus

artículo científico publicado en 2011

The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms

artículo científico publicado en 2009

The unusual conformation of cross-strand disulfide bonds is critical to the stability of β-hairpin peptides

scientific article published on 16 October 2019

The venom optimization hypothesis revisited.

artículo científico publicado en 2012

The wonderful world of spiders: preface to the special Toxicon issue on spider venoms.

artículo científico publicado en 2004

Theoretical and practical aspects of NMR studies of cells

artículo científico publicado en 1994

Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula

artículo científico publicado en 2015

Toxin delivery by the coat protein of an aphid-vectored plant virus provides plant resistance to aphids

artículo científico publicado en 2013

Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides

artículo científico publicado en 2016

Two for the Price of One: Heterobivalent Ligand Design Targeting Two Binding Sites on Voltage-Gated Sodium Channels Slows Ligand Dissociation and Enhances Potency

artículo científico publicado en 2020

Tying pest insects in knots: the deployment of spider-venom-derived knottins as bioinsecticides

scientific article published on 31 May 2019

Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores

artículo científico publicado en 2014

Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif

artículo científico publicado en 2011

Unravelling the complex venom landscapes of lethal Australian funnel-web spiders (Hexathelidae: Atracinae) using LC-MALDI-TOF mass spectrometry.

artículo científico publicado en 2013

Venom Peptides with Dual Modulatory Activity on the Voltage-Gated Sodium Channel NaV1.1 Provide Novel Leads for Development of Antiepileptic Drugs

scientific article published on 25 November 2019

Venom Profiling of a Population of the Theraphosid Spider Phlogius crassipes Reveals Continuous Ontogenetic Changes from Juveniles through Adulthood

artículo científico publicado en 2017

Venom landscapes: mining the complexity of spider venoms via a combined cDNA and mass spectrometric approach

artículo científico publicado en 2006

Venom of the Red-Bellied Black Snake Pseudechis porphyriacus Shows Immunosuppressive Potential

artículo científico publicado en 2020

Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery

artículo científico publicado en 2017

Venom-derived modulators of epilepsy-related ion channels

artículo científico publicado en 2020

Venomics as a drug discovery platform

artículo científico publicado en 2009

Venomics: a new paradigm for natural products-based drug discovery.

scientific article published on 24 February 2010

Venoms as a platform for human drugs: translating toxins into therapeutics

artículo científico

Venoms for all occasions: The functional toxin profiles of different anatomical regions in sea anemones are related to their ecological function

artículo científico publicado en 2021

Venoms of Heteropteran Insects: A Treasure Trove of Diverse Pharmacological Toolkits

artículo científico publicado en 2016

Venoms to the rescue

artículo científico publicado en 2018

Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies

artículo científico publicado en 2019

Weaponization of a Hormone: Convergent Recruitment of Hyperglycemic Hormone into the Venom of Arthropod Predators

artículo científico publicado en 2015

Were arachnids the first to use combinatorial peptide libraries?

artículo científico publicado en 2005

Widespread convergence in toxin resistance by predictable molecular evolution

artículo científico publicado en 2015

Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels.

artículo científico publicado en 2015

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

scientific article published on 11 July 2019

Zipping up transcription factors: Rational design of anti-Jun and anti-Fos peptides

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda