Lista de obras - Samia Khoury - Dominio Público Uruguay

A critical role for the programmed death ligand 1 in fetomaternal tolerance

artículo científico publicado en 2005

A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis

artículo científico publicado en 2010

A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis.

artículo científico publicado en 2010

A tale of two STAT6 knock out mice in the induction of experimental autoimmune encephalomyelitis

artículo científico publicado en 2008

Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis

scientific article published on 17 August 2009

An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity

artículo científico publicado en 2012

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

artículo científico publicado en 2008

Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis

artículo científico publicado en 1996

Assessment by flow cytometry of intracellular cytokine production in the peripheral blood cells of renal transplant recipients

artículo científico publicado en 2004

Biomarkers

Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis.

artículo científico publicado en 2011

CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis

artículo científico publicado en 2010

CTLA-4 is required for the induction of high dose oral tolerance.

artículo científico publicado en 1998

CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial.

artículo científico publicado en 2008

Cerebral pseudoatrophy or real atrophy after therapy in multiple sclerosis

artículo científico publicado en 2010

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis

artículo científico publicado en 2013

Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo

article

Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus

artículo científico publicado en 2013

Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis.

artículo científico publicado en 2007

Consensus guidelines for the diagnosis and treatment of multiple sclerosis

scientific article published on 22 April 2013

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

artículo científico publicado en 2003

Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents

scientific article published on 01 March 2019

Cyclophosphamide modulates CD4+ T cells into a T helper type 2 phenotype and reverses increased IFN-gamma production of CD8+ T cells in secondary progressive multiple sclerosis

artículo científico publicado en 2004

Cytokine shifts and tolerance in experimental autoimmune encephalomyelitis

artículo científico publicado en 2003

Cytokines in multiple sclerosis: from bench to bedside

artículo científico publicado en 2005

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

artículo científico publicado en 2008

Daclizumab in treatment of multiple sclerosis patients

artículo científico publicado en 2009

Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis

artículo científico publicado en 2009

Development, psychometric properties, and pilot norms of the first Arabic indigenous memory test: The Verbal Memory Arabic Test (VMAT)

scientific article published on 22 June 2020

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

artículo científico publicado en 2007

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

artículo científico publicado en 2004

Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis

artículo científico publicado en 2008

Effect of vitamin D replacement on immunological biomarkers in patients with multiple sclerosis

artículo científico publicado en 2017

Efficacy and safety of natalizumab extended interval dosing

Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration

artículo científico publicado en 2007

Erratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cells

scholarly article published in Nature Immunology

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex

artículo científico publicado en 2004

Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy

artículo científico publicado en 2018

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

artículo científico publicado en 2012

HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study

article

IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+) T cells via CD40-CD40 ligand interactions

artículo científico publicado en 2002

IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2.

scientific article published on 19 August 2013

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

scientific journal article

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

scholarly article

Immune deviation following pulse cyclophosphamide/methylprednisolone treatment of multiple sclerosis: Increased interleukin-4 production and associated eosinophilia

article

Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis.

artículo científico publicado en 2011

Immunopathogenesis of multiple sclerosis

Immunotherapy for neurological diseases

scientific article published on 04 June 2008

In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity

artículo científico

In vivo mechanisms of acquired thymic tolerance

artículo científico publicado en 1997

Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study.

artículo científico publicado en 2009

Increased Th17 response to myelin peptides in pediatric MS.

artículo científico publicado en 2012

Increased leptin and A-FABP levels in relapsing and progressive forms of MS

artículo científico publicado en 2013

Increased percentage of IL-12+ monocytes in the blood correlates with the presence of active MRI lesions in MS

artículo científico publicado en 2001

Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies

artículo científico publicado en 2006

Interferon-beta treatment alters peripheral blood monocytes chemokine production in MS patients

scientific article published on 01 May 2002

Kappa light chains in spinal fluid for diagnosing multiple sclerosis

artículo científico publicado en 1994

Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability.

artículo científico publicado en 2005

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

artículo científico publicado en 2009

MECHANISMS OF INDIRECT ALLORECOGNITION

artículo científico publicado en 1998

Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study

artículo científico publicado en 2011

Mechanisms of oral tolerance by MHC peptides

artículo científico publicado en 1996

Medication Treatment in Multiple Sclerosis

Medulla Oblongata Volume: A Biomarker of Spinal Cord Damage and Disability in Multiple Sclerosis: Fig 1

artículo científico publicado en 2008

Modulating co-stimulation

artículo científico publicado en 2007

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

artículo científico publicado en 2011

Multiple Sclerosis

Multiple sclerosis: what have we learned from magnetic resonance imaging studies?

artículo científico publicado en 1998

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

artículo científico publicado en 2004

Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions

scientific article published on 01 March 2003

Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells.

artículo científico publicado en 2009

Neural stem cell biology may be well suited for improving brain tumor therapies.

artículo científico publicado en 2003

Neural stem cells and the future treatment of neurological diseases: raising the standard

artículo científico publicado en 2008

No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50

artículo científico publicado en 2013

Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development

artículo científico publicado en 2011

Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells

artículo científico publicado en 2012

One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis

artículo científico publicado en 2011

Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells

artículo científico publicado en 2009

Oral administration of myelin induces antigen-specific TGF-beta 1 secreting T cells in patients with multiple sclerosis

artículo científico publicado en 1997

Oral administration of myelin induces antigen-specific TGF-beta 1-secreting T cells in multiple sclerosis patients

artículo científico publicado en 1997

Oral salbutamol decreases IL-12 in patients with secondary progressive multiple sclerosis.

artículo científico publicado en 2001

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, ⬇️

artículo científico publicado el 1 de noviembre de 1992

Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis

artículo científico publicado en 2008

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis

scientific article published on 22 September 2007

Persistent inflammation alters the function of the endogenous brain stem cell compartment

artículo científico publicado en 2008

Plasticity of Ly-6C(hi) myeloid cells in T cell regulation

artículo científico publicado en 2011

Population structure and HLA DRB1 1501 in the response of subjects with multiple sclerosis to first-line treatments

scientific article published on 27 November 2010

Potential application of tregitopes as immunomodulating agents in multiple sclerosis

artículo científico

Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale.

artículo científico publicado en 2008

Predicting short-term disability in multiple sclerosis

artículo científico publicado en 2007

Progressive Multiple Sclerosis

artículo científico publicado en 2020

Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models.

artículo científico publicado en 2006

Pulse cyclophosphamide plus methylprednisolone induces myelin-antigen-specific IL-4-secreting T cells in multiple sclerosis patients

artículo científico publicado en 1998

Rate of brain atrophy in benign vs early multiple sclerosis.

artículo científico publicado en 2009

Regulatory functions of CD8+CD28– T cells in an autoimmune disease model

artículo científico publicado en 2003

Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.

artículo científico publicado en 2011

Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells

artículo científico publicado en 2012

Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis

artículo científico publicado en 2003

SARS-CoV-2 and Multiple Sclerosis: Not all immune depleting DMTs are equal or bad

scientific article published on 08 May 2020

Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study

artículo científico publicado en 2018

Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters

artículo científico publicado en 2006

Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage

artículo científico publicado en 2000

Sex influences in autoimmune disease

artículo científico publicado en 2013

Smoking and disease progression in multiple sclerosis

artículo científico publicado en 2009

Stem cells: cross-talk and developmental programs

artículo científico publicado en 2004

Subventricular zone microglia transcriptional networks

artículo científico publicado en 2010

T cell costimulatory blockade as a novel immune intervention in autoimmune diseases

artículo científico publicado en 2001

T cell costimulatory pathways: blockade for autoimmunity

artículo científico publicado en 2003

TGF-beta induces IL-9 production from human Th17 cells.

artículo científico publicado en 2010

Th17 and Treg balance in systemic sclerosis

artículo científico publicado en 2011

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

artículo científico publicado en 2005

The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice

scientific journal article

The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis

artículo científico publicado en 2012

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

artículo científico publicado en 2003

The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis

artículo científico publicado en 2011

The roles of the new negative T cell costimulatory pathways in regulating autoimmunity

artículo científico publicado en 2004

Therapeutic strategies in multiple sclerosis

artículo científico publicado en 2011

Therapeutic strategies to prevent neurodegeneration and promote regeneration in multiple sclerosis.

artículo científico publicado en 2005

Three-year open protocol continuation study of oral tolerization with myelin antigens in multiple sclerosis and design of a phase III pivotal trial

artículo científico publicado en 1996

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

artículo científico publicado en 2005

Type17 T-cells in central nervous system autoimmunity and tumors.

artículo científico publicado en 2012

Lista de obras de Samia Khoury

A critical role for the programmed death ligand 1 in fetomaternal tolerance

A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis

A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis.

A tale of two STAT6 knock out mice in the induction of experimental autoimmune encephalomyelitis

Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis

An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis

Assessment by flow cytometry of intracellular cytokine production in the peripheral blood cells of renal transplant recipients

Biomarkers

Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis.

CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis

CTLA-4 is required for the induction of high dose oral tolerance.

CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial.

Cerebral pseudoatrophy or real atrophy after therapy in multiple sclerosis

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis

Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo

Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus

Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis.

Consensus guidelines for the diagnosis and treatment of multiple sclerosis

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents

Cyclophosphamide modulates CD4+ T cells into a T helper type 2 phenotype and reverses increased IFN-gamma production of CD8+ T cells in secondary progressive multiple sclerosis

Cytokine shifts and tolerance in experimental autoimmune encephalomyelitis

Cytokines in multiple sclerosis: from bench to bedside

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

Daclizumab in treatment of multiple sclerosis patients

Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis

Development, psychometric properties, and pilot norms of the first Arabic indigenous memory test: The Verbal Memory Arabic Test (VMAT)

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis

Effect of vitamin D replacement on immunological biomarkers in patients with multiple sclerosis

Efficacy and safety of natalizumab extended interval dosing

Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration

Erratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cells

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex

Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study

IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+) T cells via CD40-CD40 ligand interactions

IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2.

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

Immune deviation following pulse cyclophosphamide/methylprednisolone treatment of multiple sclerosis: Increased interleukin-4 production and associated eosinophilia

Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis.

Immunopathogenesis of multiple sclerosis

Immunotherapy for neurological diseases

In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity

In vivo mechanisms of acquired thymic tolerance

Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study.

Increased Th17 response to myelin peptides in pediatric MS.

Increased leptin and A-FABP levels in relapsing and progressive forms of MS

Increased percentage of IL-12+ monocytes in the blood correlates with the presence of active MRI lesions in MS

Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies

Interferon-beta treatment alters peripheral blood monocytes chemokine production in MS patients

Kappa light chains in spinal fluid for diagnosing multiple sclerosis

Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability.

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

MECHANISMS OF INDIRECT ALLORECOGNITION

Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study

Mechanisms of oral tolerance by MHC peptides

Medication Treatment in Multiple Sclerosis

Medulla Oblongata Volume: A Biomarker of Spinal Cord Damage and Disability in Multiple Sclerosis: Fig 1

Modulating co-stimulation

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

Multiple Sclerosis

Multiple sclerosis: what have we learned from magnetic resonance imaging studies?

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions

Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells.

Neural stem cell biology may be well suited for improving brain tumor therapies.

Neural stem cells and the future treatment of neurological diseases: raising the standard

No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50

Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development

Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells

One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis

Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells

Oral administration of myelin induces antigen-specific TGF-beta 1 secreting T cells in patients with multiple sclerosis