Lista de obras - Mario Schiffer - Dominio Público Uruguay

"Zebrafishing" for novel genes relevant to the glomerular filtration barrier

artículo científico publicado en 2013

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

artículo científico publicado en 2018

A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis

artículo científico publicado en 2004

A pocket guide to identify patients at risk for chronic kidney disease after liver transplantation

artículo científico publicado en 2015

ABO-incompatible renal transplantation: From saline flushes to antigen-specific immunoadsorption-Tools to overcome the barrier

artículo científico publicado en 2011

ADAMTS13--marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis

Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases.

artículo científico publicado en 2018

Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis

artículo científico publicado en 2008

Adherence to Immunosuppressive Medication Following Organ Transplantation

artículo científico publicado en 2018

An anti-phospholipase A2 receptor quantitative immunoassay and epitope analysis in membranous nephropathy reveals different antigenic domains of the receptor

artículo científico publicado en 2013

Antiphospholipase A₂ receptor autoantibodies: a comparison of three different immunoassays for the diagnosis of idiopathic membranous nephropathy

artículo científico publicado en 2014

Apoptosis in podocytes induced by TGF-beta and Smad7

artículo científico publicado en 2001

Assessment of Use and Preferences Regarding Internet-Based Health Care Delivery: Cross-Sectional Questionnaire Study.

artículo científico publicado en 2019

B-cell-attracting chemokine CXCL13 as a marker of disease activity and renal involvement in systemic lupus erythematosus (SLE).

artículo científico publicado en 2009

Back to the future: extended dialysis for treatment of acute kidney injury in the intensive care unit.

artículo científico publicado en 2010

Biopsy-diagnosed renal disease in patients after transplantation of other organs and tissues

artículo científico publicado en 2010

Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats

artículo científico publicado en 2011

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

scientific journal article

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

artículo científico publicado en 2012

CD2AP regulates SUMOylation of CIN85 in podocytes

artículo científico publicado en 2011

CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.

artículo científico publicado en 2007

CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes

artículo científico publicado en 2010

CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease.

artículo científico publicado en 2018

CXCL13 as a Novel Marker for Diagnosis and Disease Monitoring in Pediatric PTLD

CXCL13 as a new biomarker of systemic lupus erythematosus and lupus nephritis - from bench to bedside?

artículo científico publicado en 2015

Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model

scientific article published on 27 November 2019

Chemokine CXCL13 as a New Systemic Biomarker for B-Cell Involvement in Acute T Cell-Mediated Kidney Allograft Rejection.

artículo científico publicado en 2019

Chronic rejection: Differences and similarities in various solid organ transplants

artículo científico publicado en 2016

Circulating Angiopoietin-2 levels predict mortality in kidney transplant recipients: a 4-year prospective case-cohort study.

artículo científico publicado en 2014

Circulating factors cause proteinuria in parabiotic zebrafish

scientific article published on 08 March 2019

Circulating microRNAs in patients with Shiga-Toxin-producing E. coli O104:H4 induced hemolytic uremic syndrome

artículo científico publicado en 2012

Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans

artículo científico publicado en 2010

Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series

artículo científico publicado en 2011

Corticosteroid-resistant nephrotic syndrome with focal and segmental glomerulosclerosis : an update of treatment options for children

artículo científico publicado en 2008

Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.

artículo científico publicado en 2013

Deficits in sialylation impair podocyte maturation

artículo científico publicado en 2012

Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo.

artículo científico

Diminished met signaling in podocytes contributes to the development of podocytopenia in transplant glomerulopathy

artículo científico publicado en 2011

Dominant PAX2 mutations may cause steroid-resistant nephrotic syndrome and FSGS in children

artículo científico publicado en 2019

Dyadic Coping of Kidney Transplant Recipients and Their Partners: Sex and Role Differences

artículo científico publicado en 2019

Elevation of serum CXCL13 in SLE as well as in sepsis ⬇️

artículo científico publicado el 15 de noviembre de 2010

Erythropoietin prevents diabetes-induced podocyte damage.

artículo científico publicado en 2008

FERMT2 links cortical actin structures, plasma membrane tension and focal adhesion function to stabilize podocyte morphology.

artículo científico publicado en 2018

Fokal-segmentale Glomerulosklerose (FSGS)

Genomic strategies for diabetic nephropathy

artículo científico publicado en 2003

Glomerular epithelial cells in the urine: what has to be done to make them worthwhile?

artículo científico publicado en 2008

Glomerular expression of transforming growth factor-beta (TGF-beta) isoforms in mice lacking CD2-associated protein

artículo científico publicado en 2005

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

artículo científico publicado en 2006

Going single but not solo with podocytes: potentials, limitations, and pitfalls of single-cell analysis.

artículo científico publicado en 2017

How can you be adherent if you don't know how?

artículo científico publicado en 2016

IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes.

artículo científico publicado en 2006

Identification of cell and disease specific microRNAs in glomerular pathologies.

artículo científico publicado en 2019

Impact of high glucose and transforming growth factor-β on bioenergetic profiles in podocytes.

artículo científico publicado en 2012

Increase of infectious complications in ABO-incompatible kidney transplant recipients--a single centre experience.

artículo científico publicado en 2011

Inhibitory smads and tgf-Beta signaling in glomerular cells

artículo científico publicado en 2002

Kinetics of Rituximab Excretion into Urine and Peritoneal Fluid in Two Patients with Nephrotic Syndrome.

artículo científico publicado en 2017

Knockdown of the hypertension-associated gene NOSTRIN alters glomerular barrier function in zebrafish (Danio rerio).

artículo científico publicado en 2013

Leptin is a coactivator of TGF-beta in unilateral ureteral obstructive kidney disease

artículo científico

Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions

artículo científico publicado en 2005

Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome

artículo científico publicado en 2009

Massive blood transfusion after the first cut in liver transplantation predicts renal outcome and survival

artículo científico publicado en 2014

Moving beyond GWAS and eQTL Analysis to Validated Hits in Chronic Kidney Disease

artículo científico publicado en 2019

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

artículo científico publicado en 2019

Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS

artículo científico publicado en 2014

Nephrogene systemische Fibrose

article published in 2009

Nephrotische Erkrankungen im Fokus - Minimal-Change-Glomerulopathie und fokal segmentale Glomerulosklerose

Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults

artículo científico publicado en 2012

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions

scientific article published on 27 February 2019

Novel regulators of kidney development from the tips of the ureteric bud.

artículo científico

PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia

artículo científico publicado en 2011

PKC-alpha modulates TGF-beta signaling and impairs podocyte survival

artículo científico publicado en 2009

Parietal epithelia cells in the urine as a marker of disease activity in glomerular diseases.

artículo científico publicado en 2008

Pathogenesis and management of hypertension after kidney transplantation

artículo científico

Pathogenetic role of glomerular CXCL13 expression in lupus nephritis

artículo científico publicado en 2014

Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

artículo científico publicado en 2015

Podocalyxin-positive glomerular epithelial cells in urine correlate with a positive outcome in FSGS.

artículo científico publicado en 2012

Podocyte directed therapy of nephrotic syndrome-can we bring the inside out?

artículo científico

Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS

scientific article published on 30 April 2019

Podocytes from the diagnostic and therapeutic point of view

artículo científico publicado en 2017

Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis

artículo científico publicado en 2010

Preeclampsia from a renal point of view: Insides into disease models, biomarkers and therapy

artículo científico publicado en 2014

Rapid screening of glomerular slit diaphragm integrity in larval zebrafish

artículo científico publicado en 2007

Rationale and design of the RIACT-study: a multi-center placebo controlled double blind study to test the efficacy of RItuximab in Acute Cellular tubulointerstitial rejection with B-cell infiltrates in renal Transplant patients: study protocol for a

artículo científico publicado en 2012

Removal of focal segmental glomerulosclerosis (FSGS) factor suPAR using CytoSorb

artículo científico publicado en 2017

Renal co-morbidity after solid organ transplantation

Renal comorbidity after solid organ and stem cell transplantation

artículo científico publicado en 2012

Renal involvement in preeclampsia: similarities to VEGF ablation therapy

artículo científico publicado en 2010

Reply

Role of protein kinase C in podocytes and development of glomerular damage in diabetic nephropathy

artículo científico publicado en 2014

SUMOylation determines turnover and localization of nephrin at the plasma membrane.

artículo científico publicado en 2014

Serum leptin and ghrelin correlate with disease activity in ANCA-associated vasculitis

Serum neutrophil gelatinase-associated lipocalin (NGAL) in patients with Shiga toxin mediated haemolytic uraemic syndrome (STEC-HUS).

artículo científico publicado en 2013

Serum with phospholipase A2 receptor autoantibodies interferes with podocyte adhesion to collagen.

artículo científico publicado en 2014

Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition

scholarly article by Lena Schiffer et al published 1 July 2003 in Journal of Immunology

TGF-β/BMP pathways and the podocyte

artículo científico

TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes

scientific article published on 13 August 2009

The ADF/Cofilin-Pathway and Actin Dynamics in Podocyte Injury

artículo científico publicado en 2011

The Tie2 receptor antagonist angiopoietin 2 facilitates vascular inflammation in systemic lupus erythematosus

artículo científico publicado en 2008

The balance of autocrine VEGF-A and VEGF-C determines podocyte survival

artículo científico publicado en 2009

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

artículo científico publicado en 2012

The podocyte as a direct target of immunosuppressive agents

article published in 2010

The podocyte power-plant disaster and its contribution to glomerulopathy

artículo científico publicado en 2014

The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression

artículo científico publicado en 2022

The role of metabolic and haemodynamic factors in podocyte injury in diabetes

scientific article published on March 2011

The spread of resistance to imidacloprid is restricted by thermotolerance in natural populations of Drosophila melanogaster

scientific article published on 18 March 2019

Transforming Growth Factor Beta Signal Transduction in the Kidney

Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial

artículo científico publicado en 2011

Tyrosine Phosphorylation of CD2AP Affects Stability of the Slit Diaphragm Complex

scientific article published on 24 June 2019

Tyrosine phosphatase SHP-2 is a regulator of p27(Kip1) tyrosine phosphorylation

artículo científico publicado en 2008

Urinary NGAL Ratio Is Not a Sensitive Biomarker for Monitoring Acute Tubular Injury in Kidney Transplant Patients: NGAL and ATI in Renal Transplant Patients

artículo científico publicado en 2012

Urinary excretion of IGFBP-1 and -3 correlates with disease activity and differentiates focal segmental glomerulosclerosis and minimal change disease

Urinary podocyte excretion as a marker for preeclampsia.

artículo científico publicado en 2007

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

artículo científico publicado en 2012

Zinc-α2-Glycoprotein Exerts Antifibrotic Effects in Kidney and Heart

artículo científico publicado en 2015

[Impact of Emotion Regulation and Emotional Arousal on Quality of Life and Adherence of Couples after Kidney Transplantation].

artículo científico publicado en 2018

[Minimal change disease and focal segmental glomerulosclerosis]

artículo científico publicado en 2019

[Transplant Surgeon Meets Nephrologist: Important Nephrological Aspects Before and After Kidney or Liver Transplantation]

artículo científico publicado en 2015

aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation

artículo científico publicado en 2013

Lista de obras de Mario Schiffer

"Zebrafishing" for novel genes relevant to the glomerular filtration barrier

A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes.

A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis

A pocket guide to identify patients at risk for chronic kidney disease after liver transplantation

ABO-incompatible renal transplantation: From saline flushes to antigen-specific immunoadsorption-Tools to overcome the barrier

ADAMTS13--marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis

Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases.

Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis

Adherence to Immunosuppressive Medication Following Organ Transplantation

An anti-phospholipase A2 receptor quantitative immunoassay and epitope analysis in membranous nephropathy reveals different antigenic domains of the receptor

Antiphospholipase A₂ receptor autoantibodies: a comparison of three different immunoassays for the diagnosis of idiopathic membranous nephropathy

Apoptosis in podocytes induced by TGF-beta and Smad7

Assessment of Use and Preferences Regarding Internet-Based Health Care Delivery: Cross-Sectional Questionnaire Study.

B-cell-attracting chemokine CXCL13 as a marker of disease activity and renal involvement in systemic lupus erythematosus (SLE).

Back to the future: extended dialysis for treatment of acute kidney injury in the intensive care unit.

Biopsy-diagnosed renal disease in patients after transplantation of other organs and tissues

Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

CD2AP regulates SUMOylation of CIN85 in podocytes

CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.

CIN85/RukL is a novel binding partner of nephrin and podocin and mediates slit diaphragm turnover in podocytes

CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease.

CXCL13 as a Novel Marker for Diagnosis and Disease Monitoring in Pediatric PTLD

CXCL13 as a new biomarker of systemic lupus erythematosus and lupus nephritis - from bench to bedside?

Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model

Chemokine CXCL13 as a New Systemic Biomarker for B-Cell Involvement in Acute T Cell-Mediated Kidney Allograft Rejection.

Chronic rejection: Differences and similarities in various solid organ transplants

Circulating Angiopoietin-2 levels predict mortality in kidney transplant recipients: a 4-year prospective case-cohort study.

Circulating factors cause proteinuria in parabiotic zebrafish

Circulating microRNAs in patients with Shiga-Toxin-producing E. coli O104:H4 induced hemolytic uremic syndrome

Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans

Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series

Corticosteroid-resistant nephrotic syndrome with focal and segmental glomerulosclerosis : an update of treatment options for children

Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.

Deficits in sialylation impair podocyte maturation

Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo.

Diminished met signaling in podocytes contributes to the development of podocytopenia in transplant glomerulopathy

Dominant PAX2 mutations may cause steroid-resistant nephrotic syndrome and FSGS in children

Dyadic Coping of Kidney Transplant Recipients and Their Partners: Sex and Role Differences

Elevation of serum CXCL13 in SLE as well as in sepsis ⬇️

Erythropoietin prevents diabetes-induced podocyte damage.

FERMT2 links cortical actin structures, plasma membrane tension and focal adhesion function to stabilize podocyte morphology.

Fokal-segmentale Glomerulosklerose (FSGS)

Genomic strategies for diabetic nephropathy

Glomerular epithelial cells in the urine: what has to be done to make them worthwhile?

Glomerular expression of transforming growth factor-beta (TGF-beta) isoforms in mice lacking CD2-associated protein

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

Going single but not solo with podocytes: potentials, limitations, and pitfalls of single-cell analysis.

How can you be adherent if you don't know how?

IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes.

Identification of cell and disease specific microRNAs in glomerular pathologies.

Impact of high glucose and transforming growth factor-β on bioenergetic profiles in podocytes.

Increase of infectious complications in ABO-incompatible kidney transplant recipients--a single centre experience.

Inhibitory smads and tgf-Beta signaling in glomerular cells

Kinetics of Rituximab Excretion into Urine and Peritoneal Fluid in Two Patients with Nephrotic Syndrome.

Knockdown of the hypertension-associated gene NOSTRIN alters glomerular barrier function in zebrafish (Danio rerio).

Leptin is a coactivator of TGF-beta in unilateral ureteral obstructive kidney disease

Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions

Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome

Massive blood transfusion after the first cut in liver transplantation predicts renal outcome and survival

Moving beyond GWAS and eQTL Analysis to Validated Hits in Chronic Kidney Disease

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS

Nephrogene systemische Fibrose

Nephrotische Erkrankungen im Fokus - Minimal-Change-Glomerulopathie und fokal segmentale Glomerulosklerose

Neurologic manifestations of E coli infection-induced hemolytic-uremic syndrome in adults

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions

Novel regulators of kidney development from the tips of the ureteric bud.

PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia

PKC-alpha modulates TGF-beta signaling and impairs podocyte survival

Parietal epithelia cells in the urine as a marker of disease activity in glomerular diseases.

Pathogenesis and management of hypertension after kidney transplantation

Pathogenetic role of glomerular CXCL13 expression in lupus nephritis

Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

Podocalyxin-positive glomerular epithelial cells in urine correlate with a positive outcome in FSGS.

Podocyte directed therapy of nephrotic syndrome-can we bring the inside out?

Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS

Podocytes from the diagnostic and therapeutic point of view