Lista de obras - Brian D Evavold - Dominio Público Uruguay

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells

scientific article published on 13 December 2019

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery

artículo científico publicado en 2019

A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets.

artículo científico publicado en 2005

A unique unresponsive CD4+ T cell phenotype post TCR antagonism

artículo científico publicado en 2009

Accessory cell function of Th2 clones

artículo científico publicado en 1989

Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling.

artículo científico publicado en 2014

Accumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells

artículo científico publicado en 2014

Amelioration of established experimental autoimmune encephalomyelitis by an MHC anchor-substituted variant of proteolipid protein 139-151.

artículo científico publicado en 2005

An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis

scientific article published on 01 February 2004

Antigenicity of passively acquired major histocompatibility antigens on T cells

artículo científico publicado en 1988

CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection

artículo científico publicado en 2018

CD43 modulates severity and onset of experimental autoimmune encephalomyelitis

artículo científico publicado en 2003

CD8+ T cell responses to a viral escape mutant epitope: active suppression via altered SHP-1 activity

artículo científico publicado en 2009

CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments ⬇️

artículo científico publicado el 5 de enero de 2012

Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.

artículo científico publicado en 2017

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas

scientific article published on 01 January 1992

Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.

artículo científico publicado en 2016

Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.

artículo científico publicado en 2017

Cutting Edge: Resident Memory CD8 T Cells Express High-Affinity TCRs

artículo científico publicado en 2015

Cutting edge: dependence of TCR antagonism on Src homology 2 domain-containing protein tyrosine phosphatase activity

artículo científico publicado en 2003

Cutting edge: dueling TCRs: peptide antagonism of CD4+ T cells with dual antigen specificities.

artículo científico publicado en 1999

DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity

artículo científico publicado en 2016

DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope

scientific article published on 01 May 2000

Defining the parameters necessary for T-cell recognition of ligands that vary in potency.

artículo científico publicado en 2004

Degenerate recognition of T cell epitopes: impact of T cell receptor reserve and stability of peptide:MHC complexes.

artículo científico publicado en 2004

Delayed antigen presentation by epidermal Langerhans cells to cloned T h1 and T h2 cells.

artículo científico publicado en 1990

Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells

artículo científico publicado en 2013

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.

artículo científico publicado en 2018

Direct activation of murine resting T cells by con A or anti-CD3 Ig.

artículo científico publicado en 1989

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

scientific article published on 21 August 2019

Dissection of the Hb(64-76) determinant reveals that the T cell receptor may have the capacity to differentially signal.

artículo científico publicado en 1992

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.

artículo científico publicado en 2017

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

scientific journal article

Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire

artículo científico publicado en 2013

Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells.

artículo científico publicado en 2015

High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses ⬇️

artículo científico publicado el 10 de enero de 2011

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

scientific article published on 01 September 2020

Identification of T cell clones without the need for sequencing.

artículo científico publicado en 2015

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

scientific article published in Nature

Induction of anergy by antibody blockade of TCR in myelin oligodendrocyte glycoprotein-specific cells

artículo científico publicado en 2008

Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network

artículo científico publicado en 2013

Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters

artículo científico publicado en 2012

Kinetics of MHC-CD8 interaction at the T cell membrane.

artículo científico publicado en 2007

Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen

artículo científico publicado en 2008

Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics

artículo científico publicado en 2012

Low-Affinity Memory CD8+ T Cells Mediate Robust Heterologous Immunity.

artículo científico publicado en 2016

Low-affinity CD4+ T cells are major responders in the primary immune response

scientific article published on 15 December 2016

Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response

artículo científico publicado en 2015

MHC Bias by T Cell Receptors: Genetic Evidence for MHC and TCR Coevolution.

artículo científico publicado en 2016

MHC variant peptide-mediated anergy of encephalitogenic T cells requires SHP-1.

artículo científico publicado en 2008

Modification of peptide interaction with MHC creates TCR partial agonists

artículo científico publicado en 2004

Modulation of MOG 37-50-specific CD8+ T cell activation and expansion by CD43

artículo científico publicado en 2006

Modulation of T cell development by an endogenous altered peptide ligand

artículo científico publicado en 1995

NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease

artículo científico publicado en 2017

Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE.

artículo científico publicado en 2009

Peptide immunization elicits polyomavirus-specific MHC class ib-restricted CD8 T cells in MHC class ia allogeneic mice.

artículo científico publicado en 2013

Persistence of peptide-induced CD4+ T cell anergy in vitro

artículo científico publicado en 1998

Pillars article: separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science. 1991. 252: 1308-1310.

artículo científico publicado en 2011

Production of IL-2 and IFN by TH2 clones

scientific article published on 01 May 1989

Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread

artículo científico publicado en 2014

Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions.

artículo científico publicado en 2016

Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55.

artículo científico publicado en 2003

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation.

artículo científico publicado en 2016

Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease

artículo científico publicado en 2015

Self-reactive human CD4 T cell clones form unusual immunological synapses

artículo científico publicado en 2012

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

artículo científico publicado en 1991

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides

scientific article published on 01 April 1993

Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands

artículo científico publicado en 1995

Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

scientific article published on 01 January 2005

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response.

artículo científico publicado en 2016

Stimulation of peripheral blood T cells by an activated T-cell line: a novel human autologous T-T lymphocyte reaction

artículo científico publicado en 1991

Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis

artículo científico publicado en 2012

T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103+ Memory Status of CD8 T Cells in the Brain.

artículo científico publicado en 2018

T cell inducing determinants contain a hierarchy of residues contacting the T cell receptor

artículo científico publicado el 1 de julio de 1991

T cell recognition of weak ligands: roles of signaling, receptor number, and affinity

artículo científico publicado en 2011

T helper 2 (Th2) but not Th1 clones co-stimulate resting T cells in the presence of anti-CD3 monoclonal antibody

scientific article published on 01 January 1989

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

artículo científico publicado en 2014

TCR antagonism by peptide requires high TCR expression

scientific article published on 01 August 2008

TCR reserve: a novel principle of CD4 T cell activation by weak ligands

artículo científico publicado en 2003

Targeted loss of SHP1 in murine thymocytes dampens TCR signaling late in selection

artículo científico publicado en 2016

Targeting transcriptional coregulator OCA-B/Pou2af1 blocks activated autoreactive T cells in the pancreas and type 1 diabetes

scientific article published on 01 March 2021

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

artículo científico publicado en 2010

The processing and presentation of the self-antigen hemoglobin. Self-reactivity can be limited by antigen availability and costimulator expression

scientific article published on 01 November 1991

The syngeneic T-T lymphocyte reaction (STTLR). I. Induction of primary T anti-T cell proliferative responses in T cell cultures stimulated with self- and antigen-reactive T cells.

artículo científico publicado en 1986

Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

artículo científico publicado en 1993

Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.

artículo científico publicado en 2009

Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination ⬇️

artículo científico publicado el 20 de enero de 2011

Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses

artículo científico publicado en 2016

Lista de obras de Brian D Evavold

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery

A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets.

A unique unresponsive CD4+ T cell phenotype post TCR antagonism

Accessory cell function of Th2 clones

Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling.

Accumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells

Amelioration of established experimental autoimmune encephalomyelitis by an MHC anchor-substituted variant of proteolipid protein 139-151.

An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis

Antigenicity of passively acquired major histocompatibility antigens on T cells

CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection

CD43 modulates severity and onset of experimental autoimmune encephalomyelitis

CD8+ T cell responses to a viral escape mutant epitope: active suppression via altered SHP-1 activity

CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments ⬇️

Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas

Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.

Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.

Cutting Edge: Resident Memory CD8 T Cells Express High-Affinity TCRs

Cutting edge: dependence of TCR antagonism on Src homology 2 domain-containing protein tyrosine phosphatase activity

Cutting edge: dueling TCRs: peptide antagonism of CD4+ T cells with dual antigen specificities.

DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity

DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope

Defining the parameters necessary for T-cell recognition of ligands that vary in potency.

Degenerate recognition of T cell epitopes: impact of T cell receptor reserve and stability of peptide:MHC complexes.

Delayed antigen presentation by epidermal Langerhans cells to cloned T h1 and T h2 cells.

Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.

Direct activation of murine resting T cells by con A or anti-CD3 Ig.

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

Dissection of the Hb(64-76) determinant reveals that the T cell receptor may have the capacity to differentially signal.

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire

Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells.

High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses ⬇️

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

Identification of T cell clones without the need for sequencing.

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

Induction of anergy by antibody blockade of TCR in myelin oligodendrocyte glycoprotein-specific cells

Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network

Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters

Kinetics of MHC-CD8 interaction at the T cell membrane.

Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen

Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics

Low-Affinity Memory CD8+ T Cells Mediate Robust Heterologous Immunity.

Low-affinity CD4+ T cells are major responders in the primary immune response

Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response

MHC Bias by T Cell Receptors: Genetic Evidence for MHC and TCR Coevolution.

MHC variant peptide-mediated anergy of encephalitogenic T cells requires SHP-1.

Modification of peptide interaction with MHC creates TCR partial agonists

Modulation of MOG 37-50-specific CD8+ T cell activation and expansion by CD43

Modulation of T cell development by an endogenous altered peptide ligand

NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease

Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE.

Peptide immunization elicits polyomavirus-specific MHC class ib-restricted CD8 T cells in MHC class ia allogeneic mice.

Persistence of peptide-induced CD4+ T cell anergy in vitro

Pillars article: separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science. 1991. 252: 1308-1310.

Production of IL-2 and IFN by TH2 clones

Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread

Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions.

Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55.

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation.

Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease

Self-reactive human CD4 T cell clones form unusual immunological synapses

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides

Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands

Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response.

Stimulation of peripheral blood T cells by an activated T-cell line: a novel human autologous T-T lymphocyte reaction

Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis

T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103+ Memory Status of CD8 T Cells in the Brain.

T cell inducing determinants contain a hierarchy of residues contacting the T cell receptor

T cell recognition of weak ligands: roles of signaling, receptor number, and affinity

T helper 2 (Th2) but not Th1 clones co-stimulate resting T cells in the presence of anti-CD3 monoclonal antibody

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

TCR antagonism by peptide requires high TCR expression

TCR reserve: a novel principle of CD4 T cell activation by weak ligands